Conformational analysis of a marine antineoplastic macrolide, bryostatin 10

Tetrahedron

Volumn 52, Issue 7, 1996, Pages 2369-2376

  Kamano, Yoshiaki ^a   Zhang, Hui Ping ^a   Morita, Hiroshi ^b   Itokawa, Hideji ^b   Shirota, Osamu ^c   Pettit, George R ^d   Herald, Delbert L ^d   Herald, Cherry L ^d  

^a KANAGAWA UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^d ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BRYOSTATIN 10; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

EID: 0030046968     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4020(95)01080-7     Document Type: Article

References (15)

1. 37th SYMPOSIUM on THE CHEMISTRY OF NATURAL PRODUCTS, TOKUSHIMA, SYMPOSIUM PAPERS pp 672-677.
2. a) G. R. Pettit, in: "Progress in the Chemistry of Organic Natural Products." Ed. by W. Herz, G. W. Kirby, W. Steglich and Ch. Tamm, Springer-Verlag, New York, 1991, Vol. 57, pp. 153-195;
3. b) G. R. Pettit, F. Gao, D. Sengupta, J. C. Coll, C. L. Herald, D. L. Doubek, J. M. Schmidt, J. R. Van Camp, J. J. Rudloe, and R. A. Nieman, Tetrahedron, 1991, 47, 3601.
4. G. R. Pettit, C. L. Herald, D. L. Doubek, and D. L. Herald, J. Am. Chem. Soc., 1982, 104, 6846.
5. a) G. R. Pettit, D. L. Herald, F. Gao, D. Sengupta, and C. L. Herald, J. Org. Chem., 1991, 56, 1337;
6. b) Structure of bryostatin 2 was showed in Fig. 4.
7. V. J. Hruby and M. E. Hadley, in: " Design and Synthesis of Organic Molecules Based on Molecular Recognition." Ed. by G. Van Binst, Springer-Verlag, Heidelberg, 1986, pp. 269-286.
8. a) G. R. Pettit, Y. Kamano, and C. L. Herald, J. Org. Chem., 1987, 52, 2848;
9. b) Y. Kamano, H.-p. Zhang, A. Hino, M. Yoshida, G. R. Pettit, C. L. Herald, and H. Itokawa, J. Nat. Prod., in press.
10. A. A. Bothner-By, R. L. Stephens, J. Lee, C. D. Warren and R. W. Jeanloz, J. Am. Chem. Soc., 1984, 106, 811.
11. H. Kessler, Angew. Chem., 1982, 94, 509; ibid., int. Ed., 1982, 21, 512.
12. H. Kessler, Angew. Chem., 1982, 94, 509; ibid., int. Ed., 1982, 21, 512.
13. F. Mohamadi, N. G. J. Richards, W. C. Guida, R. Liskamp, M. Lipton, C. Caufield, G. Chang, T. Hendrickson and W. C. Still, J. Comput. Chem., 1990, 11, 440.
14. C. A. G. Haasnoot, F. A. A. M. De Leeuw, C. Altona, Tetrahedron. 1980, 36, 2783.
15. 6b)