5-Azacytidine- and Hoechst-induced aneuploidy in Indian muntjac

Mutation Research-Genetic Toxicology and Environmental Mutagenesis

Volumn 466, Issue 1, 2000, Pages 79-86

  Vig, Baldev K ^a   Hallett, William H ^a  

^a UNIVERSITY OF NEVADA   (United States)

Author keywords

5 Azacytidine; Aneuploidy; Hoechst; Indian muntjac

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL;

ANEUPLOIDY; ARTICLE; CHROMOSOME ABERRATION; CYTOGENETICS; HETEROCHROMATIN; MITOSIS; NONHUMAN; PRIORITY JOURNAL; Y CHROMOSOME;

ANEUPLOIDY; ANIMALS; AZACITIDINE; BISBENZIMIDE; CELLS, CULTURED; CHROMOSOME ABERRATIONS; KARYOTYPING; MALE; MUNTJACS; Y CHROMOSOME;

MUNTIACUS MUNTJAK;

EID: 0034599052     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(00)00006-1     Document Type: Article

References (21)

1. [1] R.C. Allshire, E.R. Nimmo, K. Ekwall, J.P. Javarzet, G. Cranston, Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation, Genes Dev. 9 (1995) 218-233.
2. [2] B.K. Vig, Sequence of centromere separation: role of centromeric heterochromatin, Genetics 102 (1982) 795-806.
3. [3] I. Hilwig, A. Gropp, Decondensation of constitutive heterochromatin in L cell chromosomes by a benzimidazole compound (Hoechst 33258), Exp. Cell. Res. 81 (1973) 474-477.
4. [4] B.A. Hamkalo, K. Lundgren, M.Z. Radic, M. Saghbini. Molecular features of heterochromatin condensation, in: B.K. Vig (Ed.), Chromosome Segregation and Aneuploidy, Sponger-Verlag-NATO ASI Series H: Cell Biology, Vol. 72, 1993, pp. 151-164.
5. [5] P.R. Turner, W.A. Denny, The mutagenic propertes of DNA minor groove binding ligands, Mutat. Res. 355 (1996) 141-169.
6. [6] B.K. Vig, M. Willcourt, Decondensation of pericentric heterochromatin alters the sequence of centromere separation in mouse cells, Chromosoma 107 (1998) 417-423.
7. [7] J.B. Mailhes, D. Young, S.N. London, Postovulatory oocyte ageing and aneuploidy, Biol. Reprod. 58 (1998) 1206-1210.
8. [8] D. Cimini, C. Tanzarella, F. Degrassi, Effects of 5-azacytidine on the centromeric region of human fibroblasts studied by CREST staining and in situ hybridization on cytokinesis-blocked cells, Cytogenet. Cell Genet. 72 (1996) 219-224.
9. [9] P. Van Hummelen, A. Deleener, P. Vanparys, M. Kirsch-Volders, Discrimination of aneuploidogens from clastogens by C-banding, DNA and area measurements of micronuclei from mouse bone marrow, Mutat. Res. 271 (1992) 13-28.
10. [10] H. Stopper, C. Korber, D. Schiffmann, W.J. Caspary, Cell-cycle dependent micronucleus formation and mitotic disturbances induced by 5-azacytidine in mammalian cells, Mutat. Res. 300 (1993) 165-177.
11. [11] H.M. Foss, C.J. Roberts, K.M. Claeys, E.U. Selker, Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation, Science 262 (1993) 1737-1741.
12. [12] F.K. Zimmermann, I. Scheel, Genetic effects of 5-azacytidine in Saccharomyces cerevisiae, Mutat. Res. 139 (1984) 21-24.
13. 2 chromosome, Mutagenesis 13 (1998) 33-37.
14. [14] D. Latour, B.K. Vig, E.M. Finze, N. Paweletz, The centromeres of the Indian muntjac: evidence for the existence of multiple centromeres, Mutat. Res. 356 (1996) 187-195.
15. [15] M. Lopez, B.K. Vig, Sequence of centromere separation: effect of 5-azacytidine-induced epigenetic alterations (Unpublished).
16. [16] B.K. Vig, Centromere: a candidate for face lift, Mol. Environ. Mutagen. 32 (1998) 197-199.
17. [17] B.K. Vig, N. Paweletz, D. Schroeter, Review: the centromere-kinetochore complex in cancer, Cancer J. 6 (1993) 243-252.
18. [18] P.H. Fitzgerald, Premature centromere division and aneuploidy, in: B.K. Vig, A.A. Sandberg (Eds.), Aneuploidy, Part A. Liss, New York, 1987, pp. 249-264.
19. [19] R. Angell, First meiotic division non-disjunction in human oocytes, Am. J. Human Genet. 61 (1997) 23-32.
20. [20] J. de la Torre, V. Goyanes, J. Gosalvez, Discontinuous undercondensation of centromeric heterochromatin in mouse: evidence in Hoechst 33258-treated cells, Cytogenet. Cell Genet. 54 (1990) 55-57.
21. [21] J.L. Fernandez, V. Goyanez, C. Lopez-Fernandez, J. Gosalvez, Human α-satellite DNA are not susceptible to under-condensation after 5-azacytidine treatment, Cytogenet. Cell Genet. 65 (1994) 92-94.