-
1
-
-
0016248430
-
Comparative cytogenetic study after treatment of mouse spermatogonia with mitomycin C
-
Adler, I.-D. (1974) Comparative Cytogenetic Study After Treatment of Mouse Spermatogonia with Mitomycin C, Mutation Res., 23, 369-379.
-
(1974)
Mutation Res.
, vol.23
, pp. 369-379
-
-
Adler, I.-D.1
-
2
-
-
0028122271
-
Mutagenicity and carcinogenicity of topoisomerase-interactive agents
-
Anderson, R.D. and N.A. Berger (1994) Mutagenicity and Carcinogenicity of Topoisomerase-interactive Agents, Mutation Res., 309, 109-142.
-
(1994)
Mutation Res.
, vol.309
, pp. 109-142
-
-
Anderson, R.D.1
Berger, N.A.2
-
3
-
-
0001086027
-
Structure and synthesis of distamycin A
-
Arcamone, F., S. Penco, P. Orezzi, V. Nicolella and A. Pirelli (1964) Structure and Synthesis of Distamycin A, Nature, 203, 1064-1065.
-
(1964)
Nature
, vol.203
, pp. 1064-1065
-
-
Arcamone, F.1
Penco, S.2
Orezzi, P.3
Nicolella, V.4
Pirelli, A.5
-
4
-
-
0024523215
-
Synthesis, DNA-binding properties, and antitumor activity of novel distamycin derivatives
-
Arcamone, F.M., F. Animati, B. Barbiere, E. Configliacchi, R. D'Alessio, C. Geroni, F.C. Giuliani, E. Lazzari, M. Menozzi, N. Mongelli, S. Penco and M.A. Verini (1989) Synthesis, DNA-binding Properties, and Antitumor Activity of Novel Distamycin Derivatives, J. Med. Chem., 32, 774-778.
-
(1989)
J. Med. Chem.
, vol.32
, pp. 774-778
-
-
Arcamone, F.M.1
Animati, F.2
Barbiere, B.3
Configliacchi, E.4
Alessio, R.5
Geroni, C.6
Giuliani, F.C.7
Lazzari, E.8
Menozzi, M.9
Mongelli, N.10
Penco, S.11
Verini, M.A.12
-
5
-
-
0015377787
-
Studies on tomaymycin, a new antibiotic I. Isolation and properties of tomaymycin
-
Arima, K., M. Kohsaka, G. Tamura, H. Imanaka and H. Sakai (1972) Studies on Tomaymycin, a New Antibiotic I. Isolation and Properties of Tomaymycin, J. Antibiot., 25, 437-444.
-
(1972)
J. Antibiot.
, vol.25
, pp. 437-444
-
-
Arima, K.1
Kohsaka, M.2
Tamura, G.3
Imanaka, H.4
Sakai, H.5
-
6
-
-
0015631176
-
Potential antitumour agents. 13. Bisquaternary salts
-
Atwell, G.J. and B.F. Cain (1973) Potential Antitumour Agents. 13. Bisquaternary Salts, J. Med. Chem., 16, 673-678.
-
(1973)
J. Med. Chem.
, vol.16
, pp. 673-678
-
-
Atwell, G.J.1
Cain, B.F.2
-
7
-
-
0029006937
-
Synthesis, DNA interaction and biological activity of DNA minor groove targeted polybenzamide-linked nitrogen mustards
-
Atwell, G.J., B.M. Yaghi, P.R. Turner, M. Boyd, C. O'Connor, L.R. Ferguson, B.C. Baguley and W.A. Denny (1995) Synthesis, DNA Interaction and Biological Activity of DNA Minor Groove Targeted Polybenzamide-linked Nitrogen Mustards, Bioorg. Med. Chem., 3, 679-691.
-
(1995)
Bioorg. Med. Chem.
, vol.3
, pp. 679-691
-
-
Atwell, G.J.1
Yaghi, B.M.2
Turner, P.R.3
Boyd, M.4
Connor, C.5
Ferguson, L.R.6
Baguley, B.C.7
Denny, W.A.8
-
8
-
-
0020321719
-
Nonintercalative DNA-binding antitumour compounds
-
Baguley, B.C. (1982) Nonintercalative DNA-binding Antitumour Compounds, Mol. Cell. Biochem., 43, 167-181.
-
(1982)
Mol. Cell. Biochem.
, vol.43
, pp. 167-181
-
-
Baguley, B.C.1
-
9
-
-
0027271948
-
Effect of site specifically located mitomycin C-DNA adducts on in vitro DNA synthesis by DNA polymerases
-
Basu, A.K., C.J. Hanrahan, S.A. Malia, S. Kumar, R. Bizanek and M. Tomasz (1993) Effect of Site Specifically Located Mitomycin C-DNA Adducts on in vitro DNA Synthesis by DNA Polymerases, Biochemistry, 32, 4708-4718.
-
(1993)
Biochemistry
, vol.32
, pp. 4708-4718
-
-
Basu, A.K.1
Hanrahan, C.J.2
Malia, S.A.3
Kumar, S.4
Bizanek, R.5
Tomasz, M.6
-
10
-
-
4143063050
-
Convenient routes to substituted benzimidazoles and imidazolo[4,5-b] pyridines using nitrobenzene as oxidant
-
Bathini, Y. and J.W. Lown (1990) Convenient Routes to Substituted Benzimidazoles and Imidazolo[4,5-b] Pyridines Using Nitrobenzene as Oxidant, Synthetic Communications, 20, 955-963.
-
(1990)
Synthetic Communications
, vol.20
, pp. 955-963
-
-
Bathini, Y.1
Lown, J.W.2
-
11
-
-
0025016314
-
Molecular recognition between ligands and nucleic acids: Novel pyridine-and benzoxazole-containing agents related to hoechst 33258 that exhibit altered DNA sequence specificity deduced from footprinting analysis and spectroscopic studies
-
Bathini, Y., K.E. Rao, R.G. Shea and J.W. Lown (1990) Molecular Recognition Between Ligands and Nucleic Acids: Novel Pyridine-and Benzoxazole-Containing Agents Related to Hoechst 33258 That Exhibit Altered DNA Sequence Specificity Deduced from Footprinting Analysis and Spectroscopic Studies, Chem. Res. Toxicol., 3, 268-280.
-
(1990)
Chem. Res. Toxicol.
, vol.3
, pp. 268-280
-
-
Bathini, Y.1
Rao, K.E.2
Shea, R.G.3
Lown, J.W.4
-
12
-
-
0026585888
-
Effects of analogs of the DNA minor groove binder hoechst 33258 on topoisomerase II and I mediated activities
-
Beerman, T.A., M.M. McHugh, R. Sigmund, J.W. Lown, K.E. Rao and Y. Bathini (1992) Effects of Analogs of the DNA Minor Groove Binder Hoechst 33258 on Topoisomerase II and I Mediated Activities, Biochim. Biophys. Acta, 1131, 53-61.
-
(1992)
Biochim. Biophys. Acta
, vol.1131
, pp. 53-61
-
-
Beerman, T.A.1
McHugh, M.M.2
Sigmund, R.3
Lown, J.W.4
Rao, K.E.5
Bathini, Y.6
-
13
-
-
0026675702
-
Lethality, DNA alkylation, and cell cycle effects of adozelesin (U-73975) on rodent and human cells
-
Bhuyan, B.K., K.S. Smith, E.G. Adams, G.L. Petzold and J.P. McGovren (1992) Lethality, DNA Alkylation, and Cell Cycle Effects of Adozelesin (U-73975) on Rodent and Human Cells, Cancer Res., 52, 5687-5692.
-
(1992)
Cancer Res.
, vol.52
, pp. 5687-5692
-
-
Bhuyan, B.K.1
Smith, K.S.2
Adams, E.G.3
Petzold, G.L.4
McGovren, J.P.5
-
14
-
-
0025350619
-
Antineoplastic drugs in 1990: A review (Part II)
-
Black, D.J. and R.B. Livingston (1990) Antineoplastic Drugs in 1990: A Review (Part II), Drugs, 39, 652-673.
-
(1990)
Drugs
, vol.39
, pp. 652-673
-
-
Black, D.J.1
Livingston, R.B.2
-
15
-
-
0028809915
-
Second definitive test of proposed models for the origin of the CC-1065 and duocarmycin DNA alkylation selectivity
-
Boger, D.L. and D.S. Johnson (1995) Second Definitive Test of Proposed Models for the Origin of the CC-1065 and Duocarmycin DNA Alkylation Selectivity, J. Am. Chem. Soc., 117, 1443-1444.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 1443-1444
-
-
Boger, D.L.1
Johnson, D.S.2
-
16
-
-
0025900895
-
+-CC-1065 DNA alkylation; key studies demonstrating a noncovalent binding selectivity contribution to the alkylation selectivity
-
Boger, D.L., S.A. Munk and H. Zarrinmayeh (1991) +-CC-1065 DNA Alkylation; Key Studies Demonstrating a Noncovalent Binding Selectivity Contribution to the Alkylation Selectivity, J. Am. Chem. Soc., 113, 3980-3983.
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 3980-3983
-
-
Boger, D.L.1
Munk, S.A.2
Zarrinmayeh, H.3
-
17
-
-
0022881706
-
Characterisation of a DNA repair domain containing the dihydrofolate reductase gene in CHO cells
-
Bohr, V.A., D.S. Okumoto, L. Ho and P.C. Hanawalt (1986) Characterisation of a DNA Repair Domain Containing the Dihydrofolate Reductase Gene in CHO Cells, J. Biol. Chem., 261, 1666-1672.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 1666-1672
-
-
Bohr, V.A.1
Okumoto, D.S.2
Ho, L.3
Hanawalt, P.C.4
-
18
-
-
0023584574
-
Heterogeneous DNA damage and repair in the mammalian genome
-
Bohr, V.A., D.H. Phillips and P.C. Hanawalt (1987) Heterogeneous DNA Damage and Repair in the Mammalian Genome, Cancer Res., 47, 6426-6436.
-
(1987)
Cancer Res.
, vol.47
, pp. 6426-6436
-
-
Bohr, V.A.1
Phillips, D.H.2
Hanawalt, P.C.3
-
19
-
-
0025189585
-
Second cancers and other late side effects of cancer treatment
-
Boivin, J.-F. (1990) Second Cancers and Other Late Side Effects of Cancer Treatment, Cancer, 65, 770-775.
-
(1990)
Cancer
, vol.65
, pp. 770-775
-
-
Boivin, J.-F.1
-
20
-
-
0000507030
-
Rational design of a highly efficient irreversible DNA interstrand cross-linking agent based on the pyrrolobenzodiazepine ring system
-
Bose, D.S., A.S. Thompson, J. Ching, J.A. Hartley, M.D. Berardini, T.C. Jenkins, S. Neidle, L.H. Hurley and D.E. Thurston (1992) Rational Design of a Highly Efficient Irreversible DNA Interstrand Cross-Linking Agent Based on the Pyrrolobenzodiazepine Ring System, J. Am. Chem. Soc., 114, 4939-4941.
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 4939-4941
-
-
Bose, D.S.1
Thompson, A.S.2
Ching, J.3
Hartley, J.A.4
Berardini, M.D.5
Jenkins, T.C.6
Neidle, S.7
Hurley, L.H.8
Thurston, D.E.9
-
21
-
-
0027432789
-
Poly(ADP-ribose) polymerase can bind melphalan damaged DNA
-
Bramson, J., J. Prevost, A. Malapetsa, A.J. Noe, G.G. Poirier, S. DesNoyers, M. Alaoui-Jamali and L. Panasci (1993) Poly(ADP-ribose) Polymerase Can Bind Melphalan Damaged DNA, Cancer Res., 53, 5370-5373.
-
(1993)
Cancer Res.
, vol.53
, pp. 5370-5373
-
-
Bramson, J.1
Prevost, J.2
Malapetsa, A.3
Noe, A.J.4
Poirier, G.G.5
DesNoyers, S.6
Alaoui-Jamali, M.7
Panasci, L.8
-
22
-
-
0027994197
-
Modulation of transcription factor-DNA interactions by anticancer drugs
-
Broggini, M. and M. D'Incalci (1994) Modulation of Transcription Factor-DNA Interactions by Anticancer Drugs, AntiCancer Drug Des., 9, 373-387.
-
(1994)
Anticancer Drug Des.
, vol.9
, pp. 373-387
-
-
Broggini, M.1
Incalci, M.2
-
23
-
-
0028889093
-
DNA sequence-specific adenine alkylation by the novel antitumour drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin
-
Broggini, M., H.M. Coley, N. Mongelli, E. Presenti, M.D. Wyatt, J.A. Hartley and M. Dincalci (1995) DNA Sequence-specific Adenine Alkylation by the Novel Antitumour Drug Tallimustine (FCE 24517), A Benzoyl Nitrogen Mustard Derivative of Distamycin, Nucleic Acids Res., 23, 81-87.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 81-87
-
-
Broggini, M.1
Coley, H.M.2
Mongelli, N.3
Presenti, E.4
Wyatt, M.D.5
Hartley, J.A.6
Dincalci, M.7
-
24
-
-
0025272657
-
Crystal structure of a berenil-dodecanucleotide complex: The role of water in sequence specific ligand binding
-
Brown, D.G., M.R. Sanderson, J.V. Skelly, T.C. Jenkins, T. Brown, E. Garmann, D.I. Stuart and S. Neidle (1990) Crystal Structure of a Berenil-Dodecanucleotide Complex: The Role of Water in Sequence Specific Ligand Binding, EMBO J., 9, 1329-1334.
-
(1990)
EMBO J.
, vol.9
, pp. 1329-1334
-
-
Brown, D.G.1
Sanderson, M.R.2
Skelly, J.V.3
Jenkins, T.C.4
Brown, T.5
Garmann, E.6
Stuart, D.I.7
Neidle, S.8
-
25
-
-
0023115514
-
Specific activation of transcription initiation by the sequence-specific DNA-binding agents distamycin A and netropsin
-
Bruzik, J.P., D.T. Auble and P.L. de Haseth (1987) Specific Activation of Transcription Initiation by the Sequence-specific DNA-binding Agents Distamycin A and Netropsin, Biochemistry, 26, 950-956.
-
(1987)
Biochemistry
, vol.26
, pp. 950-956
-
-
Bruzik, J.P.1
Auble, D.T.2
De Haseth, P.L.3
-
26
-
-
0028641303
-
Detection of sequence-specific antitumor alkylating agent DNA damage from cells treated in culture and from a patient
-
Bubley, G.J., G.K. Ogata, N.P. Dupuis and B.A. Teicher (1994) Detection of Sequence-specific Antitumor Alkylating Agent DNA Damage from Cells Treated in Culture and from a Patient, Cancer Res., 54, 6325-6329.
-
(1994)
Cancer Res.
, vol.54
, pp. 6325-6329
-
-
Bubley, G.J.1
Ogata, G.K.2
Dupuis, N.P.3
Teicher, B.A.4
-
27
-
-
0016233526
-
Effects of daunomycin and anthramycin on electrocardiogram and mitochondrial metabolism of the rat heart
-
Cargill, C., E. Bachmann and G. Zbinden (1974) Effects of Daunomycin and Anthramycin on Electrocardiogram and Mitochondrial Metabolism of the Rat Heart, J. Natl. Cancer. Inst., 53, 481-486.
-
(1974)
J. Natl. Cancer. Inst.
, vol.53
, pp. 481-486
-
-
Cargill, C.1
Bachmann, E.2
Zbinden, G.3
-
28
-
-
0028303604
-
Inhibition of the in vitro integration of moloney murine leukemia virus DNA by the DNA minor groove binder netropsin
-
Carteau, S., J.F. Mouscadet, H. Goulaouic, F. Subra and C. Auclair (1994) Inhibition of the in vitro Integration of Moloney Murine Leukemia Virus DNA by the DNA Minor Groove Binder Netropsin, Biochem. Pharmacol., 47, 1821-1826.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 1821-1826
-
-
Carteau, S.1
Mouscadet, J.F.2
Goulaouic, H.3
Subra, F.4
Auclair, C.5
-
29
-
-
0013834225
-
Distamycin A, a new antiviral antibiotic
-
Cassaza, A.M., A. Fioretti, M. Ghione, M. Soldati and M.A. Verini (1965) Distamycin A, A New Antiviral Antibiotic, Antimicrob. Agents. Chemother., 5, 593-598.
-
(1965)
Antimicrob. Agents. Chemother.
, vol.5
, pp. 593-598
-
-
Cassaza, A.M.1
Fioretti, A.2
Ghione, M.3
Soldati, M.4
Verini, M.A.5
-
30
-
-
0028268380
-
Unusual structures of the tandem repetitive DNA sequences located at human centromeres
-
Catasti, P., G. Gupta, A.E. Garcia, R. Ratliff, L. Hong, P. Yau, R.K. Moyzis and E.M. Bradbury (1994) Unusual Structures of the Tandem Repetitive DNA Sequences Located at Human Centromeres, Biochemistry, 33, 3819-3830.
-
(1994)
Biochemistry
, vol.33
, pp. 3819-3830
-
-
Catasti, P.1
Gupta, G.2
Garcia, A.E.3
Ratliff, R.4
Hong, L.5
Yau, P.6
Moyzis, R.K.7
Bradbury, E.M.8
-
31
-
-
0011845637
-
Inhibitors of DNA synthesis in RNA tumour viruses: Biological implications and their mode of action
-
Chandra, P., L.K. Steel, U. Ebener, M. Woltersdorf, H. Laube and G. Will (1976) Inhibitors of DNA Synthesis in RNA Tumour Viruses: Biological Implications and their Mode of Action, Prog. Mol. Subcell. Biol., 4, 167-226.
-
(1976)
Prog. Mol. Subcell. Biol.
, vol.4
, pp. 167-226
-
-
Chandra, P.1
Steel, L.K.2
Ebener, U.3
Woltersdorf, M.4
Laube, H.5
Will, G.6
-
32
-
-
0026482586
-
Clastogenic and aneuploidogenic effects of cigarette smoke condensate, mitomycin C and vincristine sulfate
-
Channarayappa, J. Nath and T. Ong (1992) Clastogenic and Aneuploidogenic Effects of Cigarette Smoke Condensate, Mitomycin C and Vincristine Sulfate, Mutagenesis, 7, 457-460.
-
(1992)
Mutagenesis
, vol.7
, pp. 457-460
-
-
Channarayappa1
Nath, J.2
Ong, T.3
-
33
-
-
0027250617
-
Crystal structure of yeast TATA-binding protein and model for interaction with DNA
-
Chasman, D.I., K.M. Flaherty, P.A. Sharp and R.D. Kornberg (1993) Crystal Structure of Yeast TATA-binding Protein and Model for Interaction with DNA, Proc. Natl. Acad. Sci. USA, 90, 8174-8178.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8174-8178
-
-
Chasman, D.I.1
Flaherty, K.M.2
Sharp, P.A.3
Kornberg, R.D.4
-
34
-
-
0002869463
-
Covalent crosslinks and monofunctional adducts of mitomycin C in the minor grooveof DNA: Effects on DNA conformation and dynamics
-
M.H. Sarma and R.H. Sarma (Eds.), Adenine Press, New York
-
Chawla, A.K., R. Lipman and M. Tomasz, Covalent Crosslinks and Monofunctional Adducts of Mitomycin C in the Minor Grooveof DNA: Effects on DNA Conformation and Dynamics. In M.H. Sarma and R.H. Sarma (Eds.), Structure and Expression, Vol. 2, DNA and Its Drug Complexes Edn., Adenine Press, New York, 1987, pp. 305-316.
-
(1987)
Structure and Expression, Vol. 2, DNA and Its Drug Complexes Edn.
, vol.2
, pp. 305-316
-
-
Chawla, A.K.1
Lipman, R.2
Tomasz, M.3
-
35
-
-
0026769202
-
2-dimensional NMR studies of d(GGTTAATGCGGT)-d(ACCGCATTAACC) complexed with the minor groove binding drug SN-6999
-
Chen, S.M., W. Leupin, M. Rance and W.J. Chazin (1992) 2-Dimensional NMR Studies of d(GGTTAATGCGGT)-d(ACCGCATTAACC) complexed with the Minor Groove Binding Drug SN-6999, Biochemistry, 31, 4406-4413.
-
(1992)
Biochemistry
, vol.31
, pp. 4406-4413
-
-
Chen, S.M.1
Leupin, W.2
Rance, M.3
Chazin, W.J.4
-
36
-
-
0027411980
-
A new mammalian DNA topoisomerase I poison 33342: Cytotoxicity and drug resistance in human cell cultures
-
Chen, A.Y., C. Yu, A. Bodley, L.F. Peng and L.F. Liu (1993a) A New Mammalian DNA Topoisomerase I Poison 33342: Cytotoxicity and Drug Resistance in Human Cell Cultures, Cancer Res., 53, 1332-1337.
-
(1993)
Cancer Res.
, vol.53
, pp. 1332-1337
-
-
Chen, A.Y.1
Yu, C.2
Bodley, A.3
Peng, L.F.4
Liu, L.F.5
-
37
-
-
0027202339
-
DNA minor groove-binding ligands: A different class of mammalian DNA topoisomerase I inhibitors
-
Chen, A.Y., C. Yu, B. Gatto and L.F. Liu (1993b) DNA Minor Groove-binding Ligands: A Different Class of Mammalian DNA Topoisomerase I Inhibitors, Proc. Natl. Acad. Sci. USA, 90, 8131-8135.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8131-8135
-
-
Chen, A.Y.1
Yu, C.2
Gatto, B.3
Liu, L.F.4
-
38
-
-
0028206145
-
Effects of minor groove binding drugs on the interaction of TATA box binding protein and TFIIA with DNA
-
Chiang, S.Y., J. Welch, F.J. Rauscher 3rd. and T.A. Beerman (1994) Effects of Minor Groove Binding Drugs on the Interaction of TATA Box Binding Protein and TFIIA with DNA, Biochemistry, 33, 7033-7040.
-
(1994)
Biochemistry
, vol.33
, pp. 7033-7040
-
-
Chiang, S.Y.1
Welch, J.2
Rauscher, F.J.3
Beerman, T.A.4
-
39
-
-
0023494886
-
A bifurcated hydrogen-bonded conformation in the d(A · T) base pairs of the DNA dodecamer d(CGCAAATTTGCG) and its complex with distamycin
-
Coll, M., C.A. Frederick, A.H.-J. Wang and A. Rich (1987) A Bifurcated Hydrogen-bonded Conformation in the d(A · T) Base Pairs of the DNA Dodecamer d(CGCAAATTTGCG) and its Complex with Distamycin, Proc. Natl. Acad. Sci. USA, 84, 8385-8390.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 8385-8390
-
-
Coll, M.1
Frederick, C.A.2
Wang, A.H.-J.3
Rich, A.4
-
40
-
-
0016773949
-
Mechanisms of chromosome banding. VIII. Hoechst 33258-DNA interaction
-
Comings, D.E. (1975) Mechanisms of Chromosome Banding. VIII. Hoechst 33258-DNA Interaction, Chromosoms, 52, 229-243.
-
(1975)
Chromosoms
, vol.52
, pp. 229-243
-
-
Comings, D.E.1
-
41
-
-
0027197725
-
General initiation factors for RNA polymerase II
-
Conaway, R.C. and J.W. Conaway (1993) General Initiation Factors for RNA Polymerase II, Annu. Rev. Biochem., 62, 161-190.
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 161-190
-
-
Conaway, R.C.1
Conaway, J.W.2
-
42
-
-
0026641021
-
Pentamidine isethionate is negative in tests for microbial mutagenicity and chromosomal breakage in vitro
-
Connor, T.H. and Z. Trizna (1992) Pentamidine Isethionate is Negative in Tests for Microbial Mutagenicity and Chromosomal Breakage in vitro, Toxicol. Lett., 63, 69-74.
-
(1992)
Toxicol. Lett.
, vol.63
, pp. 69-74
-
-
Connor, T.H.1
Trizna, Z.2
-
44
-
-
0028942808
-
Analysis of van der Waals and electrostatic contributions of minor groove binding benzimidazoles with DNA
-
Czarny, A., D.W. Boykin, A.A. Wood, C.M. Nunn, S. Neidle, M. Zhao and W.D. Wilson (1995) Analysis of van der Waals and Electrostatic Contributions of Minor Groove Binding Benzimidazoles with DNA, J. Am. Chem. Soc., 117, 4716-4717.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 4716-4717
-
-
Czarny, A.1
Boykin, D.W.2
Wood, A.A.3
Nunn, C.M.4
Neidle, S.5
Zhao, M.6
Wilson, W.D.7
-
45
-
-
0023128722
-
Dominant mutation in mouse cells associated with resistance to hoechst 33258 dye but sensitivity to ultraviolet light and DNA base-damaging compounds
-
Debenham, P.G. and M.B.T. Webb (1986) Dominant Mutation in Mouse Cells Associated With Resistance to Hoechst 33258 Dye But Sensitivity to Ultraviolet Light and DNA Base-Damaging Compounds, Somat. Cell Mol. Genet., 13, 21-32.
-
(1986)
Somat. Cell Mol. Genet.
, vol.13
, pp. 21-32
-
-
Debenham, P.G.1
Webb, M.B.T.2
-
46
-
-
0023774712
-
New directions in the design of anticancer drugs
-
Denny, W.A. (1988) New Directions in the Design of Anticancer Drugs, Drug Des. Delivery, 3, 99-124.
-
(1988)
Drug Des. Delivery
, vol.3
, pp. 99-124
-
-
Denny, W.A.1
-
47
-
-
0018757383
-
Potential antitumor agents. 29. Quantitative structure-activity relationships for the antileukemic bisquaternary ammonium heterocycles
-
Denny, W.A., G.J. Atwell, B.C. Baguley and B.F. Cain (1979) Potential Antitumor Agents. 29. Quantitative Structure-Activity Relationships for the Antileukemic Bisquaternary Ammonium Heterocycles, J. Med. Chem., 22, 134-150.
-
(1979)
J. Med. Chem.
, vol.22
, pp. 134-150
-
-
Denny, W.A.1
Atwell, G.J.2
Baguley, B.C.3
Cain, B.F.4
-
48
-
-
0022693818
-
Design of sequence-specific DNA-binding molecules
-
Dervan, P.B. (1986) Design of Sequence-specific DNA-binding Molecules, Science, 232, 464-471.
-
(1986)
Science
, vol.232
, pp. 464-471
-
-
Dervan, P.B.1
-
49
-
-
84958869520
-
Analysis of induced mutagenesis in mammalian cells, using a simian virus 40-based shuttle vector
-
R.E. Moses and W.C. Summers (Eds.), Washington DC
-
Dixon, K., E. Roilides, R. Miskin and A.S. Levine, Analysis of Induced Mutagenesis in Mammalian Cells, Using a Simian Virus 40-Based Shuttle Vector. In R.E. Moses and W.C. Summers (Eds.), DNA Replication and Mutagenesis, American Society for Microbiology, Washington DC, 1988, pp. 472-478.
-
(1988)
DNA Replication and Mutagenesis, American Society for Microbiology
, pp. 472-478
-
-
Dixon, K.1
Roilides, E.2
Miskin, R.3
Levine, A.S.4
-
50
-
-
0026597269
-
Distamycin-induced inhibition of homeodomain-DNA complexes
-
Dorn, A., M. Affolter, M. Muller, W.J. Gehring and W. Leupin (1992) Distamycin-induced Inhibition of Homeodomain-DNA Complexes, EMBO J., 11, 279-286.
-
(1992)
EMBO J.
, vol.11
, pp. 279-286
-
-
Dorn, A.1
Affolter, M.2
Muller, M.3
Gehring, W.J.4
Leupin, W.5
-
51
-
-
0017620351
-
The selective inhibition of viral DNA synthesis by chemotherapeutic agents: An indicator of clinical usefulness
-
Drach, J.C. and C. Shipman Jr. (1977) The Selective Inhibition of Viral DNA Synthesis by Chemotherapeutic Agents: An Indicator of Clinical Usefulness, Ann. NY Acad. Sci., 284, 396-409.
-
(1977)
Ann. NY Acad. Sci.
, vol.284
, pp. 396-409
-
-
Drach, J.C.1
Shipman C., Jr.2
-
52
-
-
0020376811
-
Molecular lesions involved in the induction of sister-chromatid exchange
-
Duncan, A.M. and H.J. Evans (1982) Molecular Lesions Involved in the Induction of Sister-Chromatid Exchange, Mutation Res., 105, 423-427.
-
(1982)
Mutation Res.
, vol.105
, pp. 423-427
-
-
Duncan, A.M.1
Evans, H.J.2
-
53
-
-
0020441497
-
Cytotoxicity, mutagenicity and DNA damage by hoechst 33342
-
Durand, R.E. and P.L. Olive (1982) Cytotoxicity, Mutagenicity and DNA Damage by Hoechst 33342, J. Histochem. Cytochem., 30, 111-116.
-
(1982)
J. Histochem. Cytochem.
, vol.30
, pp. 111-116
-
-
Durand, R.E.1
Olive, P.L.2
-
54
-
-
0026707681
-
Crystal structure of a pentamidine-oligonucleotide complex: Implications for DNA binding properties
-
Edwards, K.J., T.C. Jenkins and S. Neidle (1992) Crystal Structure of a Pentamidine-oligonucleotide Complex: Implications for DNA Binding Properties, Biochemistry, 31, 7104-7109.
-
(1992)
Biochemistry
, vol.31
, pp. 7104-7109
-
-
Edwards, K.J.1
Jenkins, T.C.2
Neidle, S.3
-
55
-
-
0017715266
-
Dominant lethal mutations in male mice
-
Ehling, U.H. (1977) Dominant Lethal Mutations in Male Mice, Arch. Toxicol., 38, 1-11.
-
(1977)
Arch. Toxicol.
, vol.38
, pp. 1-11
-
-
Ehling, U.H.1
-
56
-
-
0002920175
-
Pharmacology of anticancer drugs
-
I.F. Tannock and R.P. Hill (Eds.), McGraw-Hill, New York
-
Erlichman, C., Pharmacology of Anticancer Drugs, In I.F. Tannock and R.P. Hill (Eds.), The Basic Science of Oncology, 2nd Edn., McGraw-Hill, New York, 1992, pp. 317-337.
-
(1992)
The Basic Science of Oncology, 2nd Edn.
, pp. 317-337
-
-
Erlichman, C.1
-
57
-
-
0026653984
-
Different effectiveness of 4-nitroquinoline-1-oxide, mitomycin C and ethyl methanesulfonate to induce lesions in DNA leading to sister chromatid exchange throughout successive cell cycles in Chinese hamster ovary cells
-
Escalza, P., P. Daza, J. Pinero and F. Cortes (1992) Different Effectiveness of 4-Nitroquinoline-1-Oxide, Mitomycin C and Ethyl Methanesulfonate to Induce Lesions in DNA Leading to Sister Chromatid Exchange Throughout Successive Cell Cycles in Chinese Hamster Ovary Cells, Mutagenesis, 7, 137-140.
-
(1992)
Mutagenesis
, vol.7
, pp. 137-140
-
-
Escalza, P.1
Daza, P.2
Pinero, J.3
Cortes, F.4
-
58
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E.R. and B. Vogelstein (1990) A Genetic Model for Colorectal Tumorigenesis, Cell, 61, 759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
59
-
-
0021084596
-
Induction of petite mutants in yeast by non-intercalative DNA-binding antitumour agents
-
Ferguson, L.F. and B.C. Baguley (1983) Induction of Petite Mutants in Yeast by Non-intercalative DNA-binding Antitumour Agents, Eur. J. Cancer. Clin. Oncol., 19, 1575-1583.
-
(1983)
Eur. J. Cancer. Clin. Oncol.
, vol.19
, pp. 1575-1583
-
-
Ferguson, L.F.1
Baguley, B.C.2
-
60
-
-
0028661136
-
Topoisomerase II enzymes and mutagenicity
-
Ferguson, L.R. and B.C. Baguley (1994) Topoisomerase II Enzymes and Mutagenicity, Environ. Mol. Mutagen., 24, 245-267.
-
(1994)
Environ. Mol. Mutagen.
, vol.24
, pp. 245-267
-
-
Ferguson, L.R.1
Baguley, B.C.2
-
61
-
-
0026799775
-
Induction of the cytoplasmic 'petite' mutation by chemical and physical agents in saccharomyces cerevisiae
-
Ferguson, L.R. and R.C. von Borstel (1992) Induction of the Cytoplasmic 'Petite' Mutation by Chemical and Physical Agents in Saccharomyces cerevisiae. Mutation Res., 265, 103-148.
-
(1992)
Mutation Res.
, vol.265
, pp. 103-148
-
-
Ferguson, L.R.1
Von Borstel, R.C.2
-
62
-
-
0029043115
-
Microbial mutagenic effects of the DNA minor groove binder pibenzimol (hoechst 33258) and a series of mustard analogues
-
Ferguson, L.R. and W.A. Denny (1995) Microbial Mutagenic Effects of the DNA Minor Groove Binder Pibenzimol (Hoechst 33258) and a Series of Mustard Analogues, Mutation Res., 329, 19-27.
-
(1995)
Mutation Res.
, vol.329
, pp. 19-27
-
-
Ferguson, L.R.1
Denny, W.A.2
-
63
-
-
0023931027
-
Microbial mutagenicity of chlorambucil, its half-mustard and mitomycin C: A modified screening strategy for genetic toxicology of bisalkylating anti-tumour drugs
-
Ferguson, L.R., B.D. Palmer and W.A. Denny (1988) Microbial Mutagenicity of Chlorambucil, its Half-Mustard and Mitomycin C: A Modified Screening Strategy for Genetic Toxicology of Bisalkylating Anti-tumour Drugs, Anti-Cancer Drug Des., 3, 67-76.
-
(1988)
Anti-Cancer Drug Des.
, vol.3
, pp. 67-76
-
-
Ferguson, L.R.1
Palmer, B.D.2
Denny, W.A.3
-
64
-
-
0000381728
-
Netropsin a new antibiotic produced by a Streptomyces
-
Finlay, A.C., F.A. Hochstein, B.A. Sobin and F.X. Murphy (1951) Netropsin a New Antibiotic Produced by a Streptomyces, J. Am. Chem. Soc., 73, 341-343.
-
(1951)
J. Am. Chem. Soc.
, vol.73
, pp. 341-343
-
-
Finlay, A.C.1
Hochstein, F.A.2
Sobin, B.A.3
Murphy, F.X.4
-
65
-
-
0024241772
-
The chemistry of DNA modification by antitumour antibiotics
-
Fisher, J.F. and P.A. Aristoff (1988) The Chemistry of DNA Modification by Antitumour Antibiotics, Prog. Drug Res., 32, 411-498.
-
(1988)
Prog. Drug Res.
, vol.32
, pp. 411-498
-
-
Fisher, J.F.1
Aristoff, P.A.2
-
66
-
-
0020958194
-
The genetic activity of anthramycin, tomaymycin and sibiromycin in bacterial forward-and reverse-mutation assays and in the mouse bone-marrow micronucleus test
-
Gairola, C., H. Thomas, S.L. Szeinbach and W.C. Lubawy (1983) The Genetic Activity of Anthramycin, Tomaymycin and Sibiromycin in Bacterial Forward-and Reverse-mutation Assays and in the Mouse Bone-marrow Micronucleus Test, J. Appl. Toxicol., 3, 317-320.
-
(1983)
J. Appl. Toxicol.
, vol.3
, pp. 317-320
-
-
Gairola, C.1
Thomas, H.2
Szeinbach, S.L.3
Lubawy, W.C.4
-
67
-
-
0028211441
-
DNA-binding activity and biological effects of aromatic polyamidines
-
Gambari, R. and C. Nastruzzi (1994) DNA-Binding Activity and Biological Effects of Aromatic Polyamidines, Biochem. Pharmacol., 47, 599-610.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 599-610
-
-
Gambari, R.1
Nastruzzi, C.2
-
68
-
-
0027484589
-
Minor groove binding of SN 6999 to an alkylated DNA: Molecular structure of d(CGC[e6G]AATTCGCG)/SN 6999 complex
-
Gao, Y.-G., M. Siriram, W.A. Denny and H.-J. Wang (1993) Minor Groove Binding of SN 6999 to an Alkylated DNA: Molecular Structure of d(CGC[e6G]AATTCGCG)/SN 6999 Complex, Biochemistry, 32, 9639-9648.
-
(1993)
Biochemistry
, vol.32
, pp. 9639-9648
-
-
Gao, Y.-G.1
Siriram, M.2
Denny, W.A.3
Wang, H.-J.4
-
69
-
-
0016426616
-
Replication of mitochondrial DNA. Selective inhibition of the H-strand synthesis in isolated mitochondria by sibiromycin
-
Cause, G.G.J. and S.M. Dolgilevich (1975) Replication of Mitochondrial DNA. Selective Inhibition of the H-strand Synthesis in Isolated Mitochondria by Sibiromycin, Biochim. Biophys. Acta, 383, 9-15.
-
(1975)
Biochim. Biophys. Acta
, vol.383
, pp. 9-15
-
-
Cause, G.G.J.1
Dolgilevich, S.M.2
-
70
-
-
0014601819
-
Production of the antibiotic sibiromycin by the Streptosporangium sibiricum sp. nov. culture
-
Gause, G.F., T.P. Preobrazhenskaia, L.P. Ivanitskaia and M.A. Sveshnikova (1969) [Production of the Antibiotic Sibiromycin by the Streptosporangium sibiricum sp. nov. culture], Antibiotiki., 14, 963-969.
-
(1969)
Antibiotiki.
, vol.14
, pp. 963-969
-
-
Gause, G.F.1
Preobrazhenskaia, T.P.2
Ivanitskaia, L.P.3
Sveshnikova, M.A.4
-
71
-
-
0001060019
-
The biological actions and therapeutic applications of b-chloroethylamines and sulphides
-
Gilman, A. and F.S. Phillips (1946) The Biological Actions and Therapeutic Applications of b-Chloroethylamines and Sulphides, Science, 103, 409-415.
-
(1946)
Science
, vol.103
, pp. 409-415
-
-
Gilman, A.1
Phillips, F.S.2
-
72
-
-
0027497789
-
Selective toxicity to malaria parasites by non-intercalating DNA-binding ligands
-
Ginsburg, H., E. Nissani, M. Krugliak and D.H. Williamson (1993) Selective Toxicity to Malaria Parasites by Non-intercalating DNA-binding Ligands, Mol. Biochem. Parasitol., 58, 7-15.
-
(1993)
Mol. Biochem. Parasitol.
, vol.58
, pp. 7-15
-
-
Ginsburg, H.1
Nissani, E.2
Krugliak, M.3
Williamson, D.H.4
-
73
-
-
0016261596
-
The reaction of anthramycin with DNA. 3. Properties of the complex
-
Glaubiger, D., K.W. Kohn and E. Charney (1974) The Reaction of Anthramycin with DNA. 3. Properties of the Complex, Biochim. Biophys. Acta, 361, 303-311.
-
(1974)
Biochim. Biophys. Acta
, vol.361
, pp. 303-311
-
-
Glaubiger, D.1
Kohn, K.W.2
Charney, E.3
-
74
-
-
0025986543
-
32P-end-labelled DNA of N-alkyl-N-nitrosoureas linked to minor groove binding lexitropsins
-
I.K. O'Neill, J. Chen and H. Bartsch (Eds.), IARC Scientific Publications
-
32P-end-labelled DNA of N-alkyl-N-nitrosoureas Linked to Minor Groove Binding Lexitropsins. In I.K. O'Neill, J. Chen and H. Bartsch (Eds.), Relevance To Human Cancers of N-Nitroso Compounds, Tobacco and Mycotoxins, IARC Scientific Publications, 1991, pp. 439-442.
-
(1991)
Relevance To Human Cancers of N-Nitroso Compounds, Tobacco and Mycotoxins
, pp. 439-442
-
-
Gold, B.1
Church, K.M.2
Wurdeman, R.L.3
Zhang, Y.4
Chen, F.X.5
-
75
-
-
0026531137
-
Highly conserved repetitive DNA sequences are present at human centromeres
-
Grady, D.L., R.L. Ratliff, D.L. Robinson, E.C. McCanlies, J. Meyne and R.K. Moyzis (1992) Highly Conserved Repetitive DNA Sequences are Present at Human Centromeres, Proc. Natl. Acad. Sci. USA, 89, 1695-1699.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 1695-1699
-
-
Grady, D.L.1
Ratliff, R.L.2
Robinson, D.L.3
McCanlies, E.C.4
Meyne, J.5
Moyzis, R.K.6
-
76
-
-
33751157540
-
DNA-directed alkylating agents. 6. Synthesis and antitumor activity of DNA minor groove targeted aniline mustard analogues of pibenzimol (hoechst 33258)
-
Gravatt, G.L., B.C. Baguley, W.R. Wilson and W.A. Denny (1994) DNA-Directed Alkylating Agents. 6. Synthesis and Antitumor Activity of DNA Minor Groove Targeted Aniline Mustard Analogues of Pibenzimol (Hoechst 33258), J. Med. Chem., 37, 4338-4345.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 4338-4345
-
-
Gravatt, G.L.1
Baguley, B.C.2
Wilson, W.R.3
Denny, W.A.4
-
77
-
-
0021255897
-
The reaction of anthramycin with DNA. Proton and carbon nuclear magnetic resonance studies on the structure of the anthramycin-DNA adduct
-
Graves, D.E., C. Pattaroni, B.S. Krishnan, J.M. Ostrander, L.H. Hurley and T.R. Krugh (1984) The Reaction of Anthramycin with DNA. Proton and Carbon Nuclear Magnetic Resonance Studies on the Structure of the Anthramycin-DNA Adduct, J. Biol. Chem., 259, 8202-8209.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 8202-8209
-
-
Graves, D.E.1
Pattaroni, C.2
Krishnan, B.S.3
Ostrander, J.M.4
Hurley, L.H.5
Krugh, T.R.6
-
78
-
-
0022310074
-
2 adduct from one-and two-dimensional proton NMR experiments in solution
-
2 Adduct from One-and Two-dimensional Proton NMR Experiments in Solution, Biochemistry, 24, 7573-7581.
-
(1985)
Biochemistry
, vol.24
, pp. 7573-7581
-
-
Graves, D.E.1
Stone, M.P.2
Krugh, T.R.3
-
79
-
-
0023058994
-
Visualization of the bent helix in kinetoplast DNA by electron microscopy
-
Griffith, J., M. Bleyman, C.A. Rauch, P.A. Kitchin and PT. Englund (1986) Visualization of the Bent Helix in Kinetoplast DNA by Electron Microscopy, Cell, 46, 717-724.
-
(1986)
Cell
, vol.46
, pp. 717-724
-
-
Griffith, J.1
Bleyman, M.2
Rauch, C.A.3
Kitchin, P.A.4
Englund, P.T.5
-
80
-
-
0028938202
-
Design, synthesis, DNA sequence preferential alkylation and biological evaluation of N-mustard derivatives of hoechst 33258 analogues
-
Gupta, R., H. Wang, L. Huang and J.W. Lown (1995) Design, Synthesis, DNA Sequence Preferential Alkylation and Biological Evaluation of N-Mustard Derivatives of Hoechst 33258 Analogues, Anti-Cancer Drug Des., 10, 25-41.
-
(1995)
Anti-cancer Drug Des.
, vol.10
, pp. 25-41
-
-
Gupta, R.1
Wang, H.2
Huang, L.3
Lown, J.W.4
-
81
-
-
0018239716
-
CC-1065 (NSC-298223) a new antitumour antibiotic, production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganisms
-
Hanka, L.J., A. Dietz, S.A. Gerpheide, S.L. Kuentzel and D.G. Martin (1978) CC-1065 (NSC-298223) a New Antitumour Antibiotic, Production, in vitro Biological Activity, Microbiological Assays and Taxonomy of the Producing Microorganisms, J. Antibiot., 31, 1211-1217.
-
(1978)
J. Antibiot.
, vol.31
, pp. 1211-1217
-
-
Hanka, L.J.1
Dietz, A.2
Gerpheide, S.A.3
Kuentzel, S.L.4
Martin, D.G.5
-
82
-
-
0018164896
-
Pathways of DNA repair in yeast treated with the pyrrolo[1,4]benzodiazepine antitumour antibiotics
-
Hannan, M.A. and L.H. Hurley (1978) Pathways of DNA Repair in Yeast Treated with the Pyrrolo[1,4]benzodiazepine Antitumour Antibiotics, J. Antibiot., 31, 911-913.
-
(1978)
J. Antibiot.
, vol.31
, pp. 911-913
-
-
Hannan, M.A.1
Hurley, L.H.2
-
83
-
-
0018122398
-
Mutagenic and recombinogenic effects of the antitumour antibiotic anthramycin
-
Hannan, M.A., L.H. Hurley and C. Gairola (1978) Mutagenic and Recombinogenic Effects of the Antitumour Antibiotic Anthramycin, Cancer Res., 38, 2795-2799.
-
(1978)
Cancer Res.
, vol.38
, pp. 2795-2799
-
-
Hannan, M.A.1
Hurley, L.H.2
Gairola, C.3
-
84
-
-
0022880961
-
Genotoxicity of the antitumour antibiotic CC-1065
-
Harbach, P.R., R.J. Trzos, J.H. Mazurek, D.M. Zimmer, G.L. Petzold and B.K. Bhuyan (1986) Genotoxicity of the Antitumour Antibiotic CC-1065, Mutagenesis, 1, 407-410.
-
(1986)
Mutagenesis
, vol.1
, pp. 407-410
-
-
Harbach, P.R.1
Trzos, R.J.2
Mazurek, J.H.3
Zimmer, D.M.4
Petzold, G.L.5
Bhuyan, B.K.6
-
85
-
-
0023915706
-
Mutagenicity of the antitumour antibiotic CC-1065 and its analogues in mammalian (V79) cells and bacteria
-
Harbach, P.R., D.M. Zimmer, J.H. Mazurek and B.K. Bhuyan (1988) Mutagenicity of the Antitumour Antibiotic CC-1065 and Its Analogues in Mammalian (V79) Cells and Bacteria, Cancer Res., 48, 32-36.
-
(1988)
Cancer Res.
, vol.48
, pp. 32-36
-
-
Harbach, P.R.1
Zimmer, D.M.2
Mazurek, J.H.3
Bhuyan, B.K.4
-
86
-
-
0023678944
-
Distamycin A-inducible fragile sites and cancer proneness
-
Hari, T., E. Takahashi, T. Ishihara, M. Minamihisamatsu, Y. Kaneko and M. Murata (1988) Distamycin A-Inducible Fragile Sites and Cancer Proneness, Cancer. Genet. Cytogenet., 34, 177-187.
-
(1988)
Cancer. Genet. Cytogenet.
, vol.34
, pp. 177-187
-
-
Hari, T.1
Takahashi, E.2
Ishihara, T.3
Minamihisamatsu, M.4
Kaneko, Y.5
Murata, M.6
-
87
-
-
0028149725
-
Probing the importance of the second chloroethyl arm of a benzoic acid mustard derivative of an imidazole-containing analogue of distamycin
-
Hartley, J.A., M.D. Wyatt, B.J. Garbiras, C. Richter and M. Lee (1994) Probing the Importance of the Second Chloroethyl Arm of a Benzoic Acid Mustard Derivative of an Imidazole-Containing Analogue of Distamycin, Bioorg. Med. Chem. Lett., 4, 2421-2424.
-
(1994)
Bioorg. Med. Chem. Lett.
, vol.4
, pp. 2421-2424
-
-
Hartley, J.A.1
Wyatt, M.D.2
Garbiras, B.J.3
Richter, C.4
Lee, M.5
-
88
-
-
78651034294
-
Mitomycin, a new antibiotic from Streptomyces
-
Hata, T., Y. Sano, R. Sugawara, A. Matsumae, K. Kanamori, T. Shima and T. Hoshi (1956) Mitomycin, A New Antibiotic From Streptomyces, J. Antibiotics Ser. A., 9, 141-146.
-
(1956)
J. Antibiotics Ser. A.
, vol.9
, pp. 141-146
-
-
Hata, T.1
Sano, Y.2
Sugawara, R.3
Matsumae, A.4
Kanamori, K.5
Shima, T.6
Hoshi, T.7
-
89
-
-
0023730287
-
Minireview: Rare and polymorphic fragile sites and cancer
-
Hecht, F. (1988) Minireview: Rare and Polymorphic Fragile Sites and Cancer, Cancer. Genet. Cytogenet., 34, 195-199.
-
(1988)
Cancer. Genet. Cytogenet.
, vol.34
, pp. 195-199
-
-
Hecht, F.1
-
90
-
-
0023676618
-
Nature of distamycin A-inducible fragile sites, cancer
-
Hori, T., E. Takahashi and M. Murata (1988) Nature of Distamycin A-inducible Fragile Sites, Cancer. Genet. Cytogenet., 34, 189-194.
-
(1988)
Genet. Cytogenet.
, vol.34
, pp. 189-194
-
-
Hori, T.1
Takahashi, E.2
Murata, M.3
-
91
-
-
0019417193
-
The fragile site at 16q22, distamycin a, and the normal pachytene structure of chromosome 16: Some possible inter-relationships, cytogenet
-
Hungerford, D.A. (1981) The Fragile Site at 16q22, Distamycin A, and the Normal Pachytene Structure of chromosome 16: Some possible Inter-relationships, Cytogenet. Cell. Genet., 30, 63-64.
-
(1981)
Cell. Genet.
, vol.30
, pp. 63-64
-
-
Hungerford, D.A.1
-
92
-
-
33845376321
-
Covalent binding of antitumour antibiotics in the minor groove of DNA. Mechanism of action of CC-1065 and the pyrrolo[1,4]benzodiazepmes
-
Hurley, L.H. and D.R. Needham-VanDevanter (1986) Covalent Binding of Antitumour Antibiotics in the minor Groove of DNA. Mechanism of Action of CC-1065 and the Pyrrolo[1,4]benzodiazepmes, Acc. Chem. Res., 19, 230-237.
-
(1986)
Acc. Chem. Res.
, vol.19
, pp. 230-237
-
-
Hurley, L.H.1
Needham-VanDevanter, D.R.2
-
93
-
-
0018568879
-
Proposed structure of the anthramycin-DNA adduct
-
Hurley, L.H. and R. Petrusek (1979) Proposed Structure of the Anthramycin-DNA Adduct, Nature, 282, 529-531.
-
(1979)
Nature
, vol.282
, pp. 529-531
-
-
Hurley, L.H.1
Petrusek, R.2
-
94
-
-
0021272759
-
Pyrrolo[1,4]benzodiazepine antitumour antibiotics: Chemistry, interaction with DNA and biological implications
-
Hurley, L.H. and D.E. Thurston (1984) Pyrrolo[1,4]benzodiazepine Antitumour Antibiotics: Chemistry, Interaction with DNA and Biological Implications, Pharm. Res., 52-58.
-
(1984)
Pharm. Res.
, pp. 52-58
-
-
Hurley, L.H.1
Thurston, D.E.2
-
95
-
-
0017581166
-
Pyrrolo[1,4]benzodiazepine antitumor antibiotics. In vitro interaction of anthramycin, sibiromycin and tomaymycin with DNA using specifically radiolabelled molecules
-
Hurley, L.H., C. Gairola and M. Zmijewski (1977) Pyrrolo[1,4]benzodiazepine Antitumor Antibiotics. In vitro Interaction of Anthramycin, Sibiromycin and Tomaymycin with DNA using Specifically Radiolabelled Molecules, Biochim. Biophys. Acta, 475, 521-535.
-
(1977)
Biochim. Biophys. Acta
, vol.475
, pp. 521-535
-
-
Hurley, L.H.1
Gairola, C.2
Zmijewski, M.3
-
96
-
-
0018786144
-
DNA binding, induction of unscheduled DNA synthesis, and excision of anthramycin from DNA in normal and repair-deficient human fibroblasts
-
Hurley, L.H., C. Chandler, T.F. Garner, R. Petrusek and S.G. Zimmer (1979) DNA Binding, Induction of Unscheduled DNA Synthesis, and Excision of Anthramycin from DNA in Normal and Repair-deficient Human Fibroblasts, J. Biol. Chem., 254, 605-608.
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 605-608
-
-
Hurley, L.H.1
Chandler, C.2
Garner, T.F.3
Petrusek, R.4
Zimmer, S.G.5
-
97
-
-
0024290406
-
Molecular basis for sequence-specific Dna alkylation by CC-1065
-
Hurley, L.H., C.S. Lee, J.P. McGovren, M.A. Warpehoski, M.A. Mitchell, R.C. Kelly and P.A. Aristoff (1988) Molecular Basis for Sequence-specific Dna Alkylation by CC-1065, Biochemistry, 27, 3886-3892.
-
(1988)
Biochemistry
, vol.27
, pp. 3886-3892
-
-
Hurley, L.H.1
Lee, C.S.2
McGovren, J.P.3
Warpehoski, M.A.4
Mitchell, M.A.5
Kelly, R.C.6
Aristoff, P.A.7
-
98
-
-
0022994116
-
Depletion of nicotinamide adenine dinucleotide in normal and xeroderma pigmentosum fibroblast cells by the antitumour drug CC-1065
-
Jacobson, M.K. and D. Twehous (1986) Depletion of Nicotinamide Adenine Dinucleotide in Normal and Xeroderma Pigmentosum Fibroblast Cells by the Antitumour Drug CC-1065, Biochemistry, 25, 5929-5932.
-
(1986)
Biochemistry
, vol.25
, pp. 5929-5932
-
-
Jacobson, M.K.1
Twehous, D.2
-
99
-
-
0021173386
-
Morphological and cytogenetic studies of dominant lethality induced by mitomycin C and cyclophosphamide in female germ cells
-
Jacquet, P. and P. Pire (1984) Morphological and Cytogenetic Studies of Dominant Lethality Induced by Mitomycin C and Cyclophosphamide in Female Germ Cells, Mutation Res., 128, 181-194.
-
(1984)
Mutation Res.
, vol.128
, pp. 181-194
-
-
Jacquet, P.1
Pire, P.2
-
100
-
-
0011845642
-
-
Jensch, H. (1958), Med. Chem., 6, 134-169.
-
(1958)
Med. Chem.
, vol.6
, pp. 134-169
-
-
Jensch, H.1
-
101
-
-
0028952484
-
Mitomycin C-induced distortions of DNA at minor alkylation sites
-
Jolles, B. and A. Laigle (1995) Mitomycin C-induced Distortions of DNA at Minor Alkylation Sites, Chem. Biol. Interactions, 94, 215-224.
-
(1995)
Chem. Biol. Interactions
, vol.94
, pp. 215-224
-
-
Jolles, B.1
Laigle, A.2
-
102
-
-
0028041126
-
Genetic analysis of mitomycin C hypersensitive Chinese hamster cell mutants
-
Jones, N.J. (1994) Genetic Analysis of Mitomycin C Hypersensitive Chinese Hamster Cell Mutants, Mutagenesis, 9, 477-482.
-
(1994)
Mutagenesis
, vol.9
, pp. 477-482
-
-
Jones, N.J.1
-
103
-
-
0024820573
-
Specific inhibition of DNA binding to nuclear scaffolds and histone H1 by distamycin. The role of oligo(dA)-oligo(dT) tracts
-
Kas, E., E. Izaurralde and U.K. Laemmli (1989) Specific Inhibition of DNA Binding to Nuclear Scaffolds and Histone H1 by Distamycin. The Role of Oligo(dA)-oligo(dT) Tracts, J. Mol. Biol., 210, 587-599.
-
(1989)
J. Mol. Biol.
, vol.210
, pp. 587-599
-
-
Kas, E.1
Izaurralde, E.2
Laemmli, U.K.3
-
104
-
-
0027504913
-
Crystal structure of a yeast TBP/TATA-box complex
-
Kim, Y., J.H. Geiger, S. Hahn and P.B. Sigler (1993) Crystal Structure of a Yeast TBP/TATA-box Complex, Nature, 365, 512-520.
-
(1993)
Nature
, vol.365
, pp. 512-520
-
-
Kim, Y.1
Geiger, J.H.2
Hahn, S.3
Sigler, P.B.4
-
105
-
-
0027171122
-
Correlation of DNA sequence specificity of anthramycin and tomaymycin with reaction kinetics and bending of DNA
-
Kizu, R., P.H. Draves and L.H. Hurley (1993) Correlation of DNA Sequence Specificity of Anthramycin and Tomaymycin with Reaction Kinetics and Bending of DNA, Biochemistry, 32, 8712-8722.
-
(1993)
Biochemistry
, vol.32
, pp. 8712-8722
-
-
Kizu, R.1
Draves, P.H.2
Hurley, L.H.3
-
106
-
-
0028131645
-
Crystal structure of a covalent DNA-drug adduct: Anthramycin bound to CCAACGTTGG and a molecular explanation of specificity
-
Kopka, M.L., D.S. Goodsell, I. Baikalov, K. Grzeskowiak, D. Cascio and R.E. Dickerson (1994) Crystal Structure of a Covalent DNA-drug Adduct: Anthramycin Bound to CCAACGTTGG and a Molecular Explanation of Specificity, Biochemistry, 33, 13593-13610.
-
(1994)
Biochemistry
, vol.33
, pp. 13593-13610
-
-
Kopka, M.L.1
Goodsell, D.S.2
Baikalov, I.3
Grzeskowiak, K.4
Cascio, D.5
Dickerson, R.E.6
-
107
-
-
0025970948
-
Phase II study of pibenzimol in pancreatic cancer - A southwest oncology group study
-
Kraut, E., T. Fleming, M. Segal, J. Neidhart, B.C. Behrens and J. MacDonald (1991) Phase II Study of Pibenzimol in Pancreatic Cancer - A Southwest Oncology Group Study, Invest. New Drugs, 9, 95-96.
-
(1991)
Invest. New Drugs
, vol.9
, pp. 95-96
-
-
Kraut, E.1
Fleming, T.2
Segal, M.3
Neidhart, J.4
Behrens, B.C.5
MacDonald, J.6
-
108
-
-
0024581890
-
Use of the cytokinesis-block method for the analysis of micronuclei in V79 chinese hamster lung cells: Results with mitomycin C and cyclophosphamide
-
Krishna, G., M.L. Kropko and J.C. Theiss (1989) Use of the Cytokinesis-Block Method for the Analysis of Micronuclei in V79 Chinese Hamster Lung Cells: Results with Mitomycin C and Cyclophosphamide, Mutation Res., 222, 63-69.
-
(1989)
Mutation Res.
, vol.222
, pp. 63-69
-
-
Krishna, G.1
Kropko, M.L.2
Theiss, J.C.3
-
109
-
-
0006828126
-
Novel DNA groove binding alkylators: Design, synthesis, and biological evaluation
-
Krowicki, K., J. Balzarini, E. De-Clercq, R.A. Newman and J.W. Lown (1988a) Novel DNA Groove Binding Alkylators: Design, Synthesis, and Biological Evaluation, J. Med. Chem., 31, 341-345.
-
(1988)
J. Med. Chem.
, vol.31
, pp. 341-345
-
-
Krowicki, K.1
Balzarini, J.2
De-Clercq, E.3
Newman, R.A.4
Lown, J.W.5
-
110
-
-
0005783685
-
Molecular recognition between oligopeptides and nucleic acids-rational design of sequence specific DNA binding agents
-
R.H. Sarma and M.H. Sarma (Eds.), Adenine Press, New York
-
Krowicki, K., M. Lee, J.A. Hartley, B. Ward, K. Kissinger, A. Skorobogaty, J.C. Dabrowiak and J.W. Lown (1988b) Molecular Recognition Between Oligopeptides and Nucleic Acids-Rational Design of Sequence Specific DNA Binding Agents. In R.H. Sarma and M.H. Sarma (Eds.), Structure and Expression (DNA and Its Drug Complexes), Vol. 2, Adenine Press, New York, pp. 251-271.
-
(1988)
Structure and Expression (DNA and Its Drug Complexes)
, vol.2
, pp. 251-271
-
-
Krowicki, K.1
M, L.2
Hartley, J.A.3
Ward, B.4
Kissinger, K.5
Skorobogaty, A.6
Dabrowiak, J.C.7
Lown, J.W.8
-
111
-
-
0026568179
-
Calf thymus DNA binding/bonding properties of CC-1065 and analogs as related to their biological activities and toxicities
-
Krueger, W.C. and M.D. Prairie (1992) Calf Thymus DNA Binding/Bonding Properties of CC-1065 and Analogs as Related to their Biological Activities and Toxicities, Chem. Biol. Interactions, 82, 31-46.
-
(1992)
Chem. Biol. Interactions
, vol.82
, pp. 31-46
-
-
Krueger, W.C.1
Prairie, M.D.2
-
112
-
-
0022577219
-
The base substitution fidelity of eukaryotic DNA polymerases
-
Kunkel, T.A. and P.S. Alexander (1986) The Base Substitution Fidelity of Eukaryotic DNA Polymerases, J. Biol. Chem., 261, 160-166.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 160-166
-
-
Kunkel, T.A.1
Alexander, P.S.2
-
113
-
-
0018382242
-
Induction of high frequencies of endoreduplication in mammalian cell cultures with 33258 hoechst and rubidazone
-
Kusyk, C.J. and T.C. Hsu (1979) Induction of High Frequencies of Endoreduplication in Mammalian Cell Cultures with 33258 Hoechst and Rubidazone, Cytogenet. Cell. Genet., 23, 39-43.
-
(1979)
Cytogenet. Cell. Genet.
, vol.23
, pp. 39-43
-
-
Kusyk, C.J.1
Hsu, T.C.2
-
114
-
-
0016720309
-
Induclion by alkylaling agents of sister chromatid exchanges and chromatid breaks in faconi's anemia
-
Latt, S.A., G. Stetten, L.A. Juergens, G.R. Buchanan and P.S. Gerald (1975) Induclion by Alkylaling Agents of Sister Chromatid Exchanges and Chromatid Breaks in Faconi's Anemia, Proc. Natl. Acad. Sci. USA, 72, 4066-4070.
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.72
, pp. 4066-4070
-
-
Latt, S.A.1
Stetten, G.2
Juergens, L.A.3
Buchanan, G.R.4
Gerald, P.S.5
-
115
-
-
0022620716
-
Chromosomal fragile sites and cancer-specific rearrangements
-
Le Beau, M.M. (1986) Chromosomal Fragile Sites and Cancer-Specific Rearrangements, Blood, 67, 607-608.
-
(1986)
Blood
, vol.67
, pp. 607-608
-
-
Le Beau, M.M.1
-
116
-
-
0026026533
-
Determination of the structural features of (+)-CC-1065 that are responsible for bending and winding of DNA
-
Lee, C.S., D. Sun, R. Kizu and L.H. Hurley (1991a) Determination of the Structural Features of (+)-CC-1065 that are Responsible for Bending and Winding of DNA, Chem. Res. Toxicol., 4, 203-213.
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 203-213
-
-
Lee, C.S.1
Sun, D.2
Kizu, R.3
Hurley, L.H.4
-
117
-
-
0000538873
-
Synthesis and DNA binding properties of a purine analog of bisbenzimide
-
Lee, M., P.H. Spotts, J. Eckert, C. Walker and J.A. Nobles (1991b) Synthesis and DNA Binding Properties of a Purine Analog of Bisbenzimide, Heterocycles, 32, 2093-2097.
-
(1991)
Heterocycles
, vol.32
, pp. 2093-2097
-
-
Lee, M.1
Spotts, P.H.2
Eckert, J.3
Walker, C.4
Nobles, J.A.5
-
118
-
-
0028143541
-
GC sequence specific recognition by an N-formamido, C-terminus-modified and imidazole-containing analogue of netropsin
-
Lee, M., C.S. Preti, E. Vinson, M.D. Wyatt and J.A. Hartley (1994) GC Sequence Specific Recognition by an N-formamido, C-terminus-modified and Imidazole-containing Analogue of Netropsin, J. Med. Chem., 37, 4073-4075.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 4073-4075
-
-
Lee, M.1
Preti, C.S.2
Vinson, E.3
Wyatt, M.D.4
Hartley, J.A.5
-
119
-
-
0013852032
-
Isolation and characterization of anthramycin, a new antitumour antibiotic
-
Leimgruber, W., V. Stefanovic, F. Schenker, A. Karr and J. Berger (1965) Isolation and Characterization of Anthramycin, a New Antitumour Antibiotic, J. Am. Chem. Soc., 87, 5791-5793.
-
(1965)
J. Am. Chem. Soc.
, vol.87
, pp. 5791-5793
-
-
Leimgruber, W.1
Stefanovic, V.2
Schenker, F.3
Karr, A.4
Berger, J.5
-
120
-
-
0022973816
-
2 and a minor groove binding drug
-
2 and a Minor Groove Binding Drug, Biochemistry, 25, 5902-5910.
-
(1986)
Biochemistry
, vol.25
, pp. 5902-5910
-
-
Leupin, W.1
Chazin, W.J.2
Hyberts, S.3
Denny, W.A.4
Stewart, G.M.5
Wüthrich, K.6
-
121
-
-
0026546246
-
Activation of the gadd153 promoter by genotoxic agents: A rapid and specific response to DNA damage
-
Leuthy, J.D. and N.J. Holbrook (1992) Activation of the gadd153 Promoter by Genotoxic Agents: A Rapid and Specific Response to DNA Damage, Cancer Res., 52, 5-10.
-
(1992)
Cancer Res.
, vol.52
, pp. 5-10
-
-
Leuthy, J.D.1
Holbrook, N.J.2
-
122
-
-
0025753312
-
Adozelesin, a selected lead among cyclopropylpyrroloindole analogs of the DNA-binding antibiotic, CC-1065
-
Li, L.H., R.C. Kelly, M.A. Warpehoski, J.P. McGovren, I. Gebhard and T.F. DeKoning (1991) Adozelesin, a Selected Lead Among Cyclopropylpyrroloindole Analogs of the DNA-Binding Antibiotic, CC-1065, Invest. New Drugs, 9, 137-148.
-
(1991)
Invest. New Drugs
, vol.9
, pp. 137-148
-
-
Li, L.H.1
Kelly, R.C.2
Warpehoski, M.A.3
McGovren, J.P.4
Gebhard, I.5
Dekoning, T.F.6
-
123
-
-
0026786973
-
Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue
-
Li, L.H., T.F. DeKoning, R.C. Kelly, W.C. Krueger, J.P. McGovren, G.E. Padbury, G.L. Petzold, T.L. Wallace, R.J. Ouding, M.D. Prairie and I. Gebhard (1992) Cytotoxicity and Antitumor Activity of Carzelesin, a Prodrug Cyclopropylpyrroloindole Analogue, Cancer Res., 52, 4904-4913.
-
(1992)
Cancer Res.
, vol.52
, pp. 4904-4913
-
-
Li, L.H.1
DeKoning, T.F.2
Kelly, R.C.3
Krueger, W.C.4
McGovren, J.P.5
Padbury, G.E.6
Petzold, G.L.7
Wallace, T.L.8
Ouding, R.J.9
Prairie, M.D.10
Gebhard, I.11
-
124
-
-
0025837986
-
Structure of the (+)-CC-1065-DNA adduct: Critical role of ordered water molecules and implications for involvement of phosphate catalysis in the covalent reaction
-
Lin, C.H., J.M. Beale and L.H. Hurley (1991) Structure of the (+)-CC-1065-DNA Adduct: Critical Role of Ordered Water Molecules and Implications for Involvement of Phosphate Catalysis in the Covalent Reaction, Biochemistry, 30, 3597-3602.
-
(1991)
Biochemistry
, vol.30
, pp. 3597-3602
-
-
Lin, C.H.1
Beale, J.M.2
Hurley, L.H.3
-
125
-
-
84910686808
-
Molecular analysis of mutations at the tk and HGPRT loci in human cells
-
M.M. Moore, D.M. Demarini, F.J. de Serres and K.R. Tindall (Eds.), Cold Spring Harbour Laboratory, New York
-
Little, J.B., D.W. Yandell and H.L. Liber, Molecular Analysis of Mutations at the tk and HGPRT Loci in Human Cells. In M.M. Moore, D.M. Demarini, F.J. de Serres and K.R. Tindall (Eds.), Mammalian Cell Mutagenesis, Cold Spring Harbour Laboratory, New York, 1987, pp. 225-236.
-
(1987)
Mammalian Cell Mutagenesis
, pp. 225-236
-
-
Little, J.B.1
Yandell, D.W.2
Liber, H.L.3
-
126
-
-
0016182453
-
Basisch substituierte 2,6-bis-benzimidazotderivate, eine neue chemotherapeutisch aktive korperklasse
-
Loewe, V.H. and J. Urbanietz (1974) Basisch Substituierte 2,6-Bis-benzimidazotderivate, eine Neue Chemotherapeutisch Aktive Korperklasse, Arzneimittel-Forschung (Drug Research), 24, 1927-1933.
-
(1974)
Arzneimittel-Forschung (Drug Research)
, vol.24
, pp. 1927-1933
-
-
Loewe, V.H.1
Urbanietz, J.2
-
127
-
-
0023008677
-
Echinomycin and distamycin induce rotation of nucleosome core DNA
-
Low, C.M., H.R. Drew and M.J. Waring (1986) Echinomycin and Distamycin Induce Rotation of Nucleosome Core DNA, Nucleic Acids Res., 14, 6785-6801.
-
(1986)
Nucleic Acids Res.
, vol.14
, pp. 6785-6801
-
-
Low, C.M.1
Drew, H.R.2
Waring, M.J.3
-
128
-
-
0022858456
-
Molecular recognition between oligopeptides and nucleic acids: Novel imidazole-containing oligopeptides related to netropsin that exhibit altered DNA sequence specificity
-
Lown, J.W., K. Krowicki, U.G. Bhat, A. Skorobogaty, B. Ward and J.C. Dabrowiak (1986) Molecular Recognition Between Oligopeptides and Nucleic Acids: Novel Imidazole-containing Oligopeptides Related to Netropsin that Exhibit Altered DNA Sequence Specificity, Biochemistry, 25, 7408-7416.
-
(1986)
Biochemistry
, vol.25
, pp. 7408-7416
-
-
Lown, J.W.1
Krowicki, K.2
Bhat, U.G.3
Skorobogaty, A.4
Ward, B.5
Dabrowiak, J.C.6
-
129
-
-
0028270722
-
Effects of pentamidine isethionate on Saccharomyces cerevisiae, antimicrob
-
Ludewig, G., J.M. Williams, Y. Li and C. Staben (1994) Effects of Pentamidine Isethionate on Saccharomyces cerevisiae, Antimicrob, Agents. Chemother., 38, 1123-1128.
-
(1994)
Agents. Chemother.
, vol.38
, pp. 1123-1128
-
-
Ludewig, G.1
Williams, J.M.2
Li, Y.3
Staben, C.4
-
130
-
-
0021041116
-
Determinazione dell'attivita mutagena e genotossica dell'antibiotico distamicina A
-
Mazza, G., C. Mondello, F. Nuzzo (1983) Determinazione Dell'attivita Mutagena e Genotossica Dell'antibiotico Distamicina A, G. Ital. Chemioter., 30, 39-52.
-
(1983)
G. Ital. Chemioter.
, vol.30
, pp. 39-52
-
-
Mazza, G.1
Mondello, C.2
Nuzzo, F.3
-
131
-
-
0026685873
-
Efficacy of engineering controls in reducing occupational exposure to aerosolized pentamidine
-
McDiarmid, M.A., J. Schaefer, C.L. Richard, R.E. Chaisson and B.S. Tepper (1992) Efficacy of Engineering Controls in Reducing Occupational Exposure to Aerosolized Pentamidine, Chest, 102, 1764-1766.
-
(1992)
Chest
, vol.102
, pp. 1764-1766
-
-
McDiarmid, M.A.1
Schaefer, J.2
Richard, C.L.3
Chaisson, R.E.4
Tepper, B.S.5
-
132
-
-
0021319952
-
Preliminary toxicity studies with the DNA-binding antibiotic CC-1065
-
McGovren, J.P., G.L. Clarke, E.A. Pratt and T.F. DeKoning (1984) Preliminary Toxicity Studies with the DNA-Binding Antibiotic CC-1065, J. Antibiot., 37, 63-70.
-
(1984)
J. Antibiot.
, vol.37
, pp. 63-70
-
-
McGovren, J.P.1
Clarke, G.L.2
Pratt, E.A.3
DeKoning, T.F.4
-
133
-
-
0027978310
-
CC-1065 bonding to intracellular and purified SV40 DNA: Site specificity and functional effects
-
McHugh, M.M., J.M. Woynarowski, M.A. Mitchell, L.S. Gawron, K.L. Weiland and T.A. Beerman (1994) CC-1065 Bonding to Intracellular and Purified SV40 DNA: Site Specificity and Functional Effects, Biochemistry, 33, 9158-9168.
-
(1994)
Biochemistry
, vol.33
, pp. 9158-9168
-
-
McHugh, M.M.1
Woynarowski, J.M.2
Mitchell, M.A.3
Gawron, L.S.4
Weiland, K.L.5
Beerman, T.A.6
-
134
-
-
0020042917
-
Damaging effects of fourteen chemotherapeutic drugs on mouse testis cells
-
Meistrich, M.L., M. Finch, M.F. da Cunha, U. Hacker and W.W. Au (1982) Damaging Effects of Fourteen Chemotherapeutic Drugs on Mouse Testis Cells, Cancer Res., 42, 122-131.
-
(1982)
Cancer Res.
, vol.42
, pp. 122-131
-
-
Meistrich, M.L.1
Finch, M.2
Da Cunha, M.F.3
Hacker, U.4
Au, W.W.5
-
135
-
-
0016529992
-
Accessibility of the minor groove of DNA in chromatin to the binding of antibiotics netropsin and distamycin A
-
Melnikova, A.F., A.S. Zasedatelev, A.M. Kolchinsky, G.V. Gursky, A.L. Zhuze, S.L. Grochovsky and A.D. Mirzabekov (1975) Accessibility of the Minor Groove of DNA in Chromatin to the Binding of Antibiotics Netropsin and Distamycin A, Mol. Biol. Reports, 2, 135-142.
-
(1975)
Mol. Biol. Reports
, vol.2
, pp. 135-142
-
-
Melnikova, A.F.1
Zasedatelev, A.S.2
Kolchinsky, A.M.3
Gursky, G.V.4
Zhuze, A.L.5
Grochovsky, S.L.6
Mirzabekov, A.D.7
-
136
-
-
0028950853
-
Is polyploidy an important genotoxic lesion?
-
Mitchell, I.G., T.R. Lambert, M. Burden, J. Sunderland, R.L. Porter and J.B. Carlton (1995) Is Polyploidy an Important Genotoxic Lesion?, Mutagenesis, 10, 79-83.
-
(1995)
Mutagenesis
, vol.10
, pp. 79-83
-
-
Mitchell, I.G.1
Lambert, T.R.2
Burden, M.3
Sunderland, J.4
Porter, R.L.5
Carlton, J.B.6
-
137
-
-
0027451862
-
In vitro mutagenesis induced by CC-1065 and adozelesin DNA alkylation in a transgenic mouse model
-
Monroe, T.J. and M.A. Mitchell (1993) In vitro Mutagenesis Induced by CC-1065 and Adozelesin DNA Alkylation in a Transgenic Mouse Model, Cancer Res., 53, 5690-5696.
-
(1993)
Cancer Res.
, vol.53
, pp. 5690-5696
-
-
Monroe, T.J.1
Mitchell, M.A.2
-
138
-
-
0024434477
-
Offspring from inseminations with mammalian sperm stained with hoechst 33342, either with or without flow cytometry
-
Morrel, J.M. and D.W. Dresser (1989) Offspring from Inseminations With Mammalian Sperm Stained With Hoechst 33342, Either With or Without Flow Cytometry, Mutation Res., 224, 177-183.
-
(1989)
Mutation Res.
, vol.224
, pp. 177-183
-
-
Morrel, J.M.1
Dresser, D.W.2
-
139
-
-
0023158528
-
Heritable fragile sites and cancer: Fra(16)(q22) in lymphocytes of an acute nonlymphocytic leukemia patient with inv(16)(p13q22)
-
Murata, M., E. Takahashi, T. Ishihara, M. Minamihisamatsu, T. Takagi, Y. Kaneko and T. Hori (1987) Heritable Fragile Sites and Cancer: Fra(16)(q22) in Lymphocytes of an Acute Nonlymphocytic Leukemia Patient with inv(16)(p13q22), Cancer. Genet. Cytogenet., 25, 81-86.
-
(1987)
Cancer. Genet. Cytogenet.
, vol.25
, pp. 81-86
-
-
Murata, M.1
Takahashi, E.2
Ishihara, T.3
Minamihisamatsu, M.4
Takagi, T.5
Kaneko, Y.6
Hori, T.7
-
140
-
-
0015113862
-
Histological study of dog organs under the effect of sibiromycin
-
Muraveiskaia, V.S. (1971) [Histological Study of Dog Organs Under the Effect of Sibiromycin], Antibiotiki., 16, 810-816.
-
(1971)
Antibiotiki.
, vol.16
, pp. 810-816
-
-
Muraveiskaia, V.S.1
-
141
-
-
0000102949
-
Poly(ADP-ribose) polymerase: A molecular nick-sensor
-
Murcia, G. and J. Murcia (1994) Poly(ADP-ribose) Polymerase: A Molecular Nick-sensor, TIBS, 19, 172-176.
-
(1994)
TIBS
, vol.19
, pp. 172-176
-
-
Murcia, G.1
Murcia, J.2
-
142
-
-
0028355768
-
Ultraviolet light-induced cleavage of DNA in the presence of iodohoechst 33258: The sequence specificity of the reaction
-
Murray, V. and R.F. Martin (1994) Ultraviolet Light-induced Cleavage of DNA in the Presence of IodoHoechst 33258: The Sequence Specificity of the Reaction, Nucleic Acids Res., 22, 506-513.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 506-513
-
-
Murray, V.1
Martin, R.F.2
-
143
-
-
0026473090
-
A comparison of the rates of reaction and function of UVRB in UVRABC-and UVRAB-mediated anthramycin-N2-guanine-DNA repair
-
Nazimiec, M., L. Grossman and M.S. Tang (1992) A Comparison of the Rates of Reaction and Function of UVRB in UVRABC-and UVRAB-mediated Anthramycin-N2-guanine-DNA Repair, J. Biol. Chem., 267, 24716-24724.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 24716-24724
-
-
Nazimiec, M.1
Grossman, L.2
Tang, M.S.3
-
144
-
-
0028232159
-
The relevance of drug DNA sequence specificity to anti-tumour activity
-
Neidle, S., M.S. Puvvada and D.E. Thurston (1994) The Relevance of Drug DNA Sequence Specificity to Anti-tumour Activity, Eur. J. Cancer, 30A, 567-568.
-
(1994)
Eur. J. Cancer
, vol.30 A
, pp. 567-568
-
-
Neidle, S.1
Puvvada, M.S.2
Thurston, D.E.3
-
145
-
-
0021196009
-
Comparison of 6-thioguanine-resistant mutation and sister chromatid exchanges in Chinese hamster V79 cells with forty chemical and physical agents
-
Nishi, Y., M.M. Hasegawa, M. Taketomi, Y. Ohkawa and N. Inui (1984) Comparison of 6-Thioguanine-Resistant Mutation and Sister Chromatid Exchanges in Chinese Hamster V79 Cells with Forty Chemical and Physical Agents, Cancer Res., 44, 3270-3279.
-
(1984)
Cancer Res.
, vol.44
, pp. 3270-3279
-
-
Nishi, Y.1
Hasegawa, M.M.2
Taketomi, M.3
Ohkawa, Y.4
Inui, N.5
-
146
-
-
0000814811
-
Mitotic inhibition and chromosome damage by mitomycin in human leukocyte cultures
-
Nowell, P.C. (1964) Mitotic Inhibition and Chromosome Damage by Mitomycin in Human Leukocyte Cultures, Exp. Cell Res., 33, 445-449.
-
(1964)
Exp. Cell Res.
, vol.33
, pp. 445-449
-
-
Nowell, P.C.1
-
148
-
-
0025155089
-
The interaction with DNA of wild-type and mutant fushi tarazu homeodomains
-
Percival-Smith, A., M. Muller, M. Affolter and W.J. Gehring (1990) The Interaction with DNA of Wild-type and Mutant Fushi Tarazu Homeodomains, EMBO J., 9, 3967-3974.
-
(1990)
EMBO J.
, vol.9
, pp. 3967-3974
-
-
Percival-Smith, A.1
Muller, M.2
Affolter, M.3
Gehring, W.J.4
-
149
-
-
0025293353
-
Molecular modelling study of changes induced by netropsin binding to nucleosome core particles
-
Perez, J.J. and J. Portugal (1990) Molecular Modelling Study of Changes Induced By Netropsin Binding to Nucleosome Core Particles, Nucleic Acids Res., 18, 3731-3737.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 3731-3737
-
-
Perez, J.J.1
Portugal, J.2
-
150
-
-
0019394787
-
Pyrrol[1,4]benzodiazepine antibiotics. Proposed structures and characteristics of the in vitro deoxyribonucleic acid adducts of anthramycin, tomaymycin, sibiromycin, and neothramycins A and B
-
Petrusek, R.L., G.L. Anderson, T.F. Garner, Q.L. Fannin, D.J. Kaplan, S.G. Zimmer and L.H. Hurley (1981) Pyrrol[1,4]benzodiazepine Antibiotics. Proposed Structures and Characteristics of the in vitro Deoxyribonucleic Acid Adducts of Anthramycin, Tomaymycin, Sibiromycin, and Neothramycins A and B, Biochemistry, 20, 1111-1119.
-
(1981)
Biochemistry
, vol.20
, pp. 1111-1119
-
-
Petrusek, R.L.1
Anderson, G.L.2
Garner, T.F.3
Fannin, Q.L.4
Kaplan, D.J.5
Zimmer, S.G.6
Hurley, L.H.7
-
151
-
-
0020327397
-
Reaction of anthramycin with DNA. Biological consequences of DNA damage in normal and xeroderma pigmentosum cell
-
Petrusek, R.L., E.L. Uhlenhopp, N. Duteau and L.H. Hurley (1982) Reaction of Anthramycin with DNA. Biological Consequences of DNA Damage in Normal and Xeroderma Pigmentosum Cell, J. Biol. Chem., 257, 6207-6216.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 6207-6216
-
-
Petrusek, R.L.1
Uhlenhopp, E.L.2
Duteau, N.3
Hurley, L.H.4
-
152
-
-
0026322735
-
Biological profile of FCE 24517, A novel benzoyl mustard analogue of distamycin A
-
Pezzoni, G., M. Grandi, G. Biasoli, L. Capolongo, D. Ballinari, F.C. Giuliani, B. Barbieri, A. Pastori, E. Presenti, N. Mongelli and F. Spreafico (1991) Biological Profile of FCE 24517, A Novel Benzoyl Mustard Analogue of Distamycin A, Br. J. Cancer, 64, 1047-1050.
-
(1991)
Br. J. Cancer
, vol.64
, pp. 1047-1050
-
-
Pezzoni, G.1
Grandi, M.2
Biasoli, G.3
Capolongo, L.4
Ballinari, D.5
Giuliani, F.C.6
Barbieri, B.7
Pastori, A.8
Presenti, E.9
Mongelli, N.10
Spreafico, F.11
-
153
-
-
0022848443
-
Kinetics and sequence specificity of drug-DNA interactions: An in vitro transcription assay
-
Phillips, D.R. and D.M. Crothers (1986) Kinetics and Sequence Specificity of Drug-DNA Interactions: An in vitro Transcription Assay, Biochemistry, 25, 7355-7362.
-
(1986)
Biochemistry
, vol.25
, pp. 7355-7362
-
-
Phillips, D.R.1
Crothers, D.M.2
-
154
-
-
0026012583
-
Induction of micronuclei in mouse bone marrow cells: An evaluation of nucleoside analogues used in the treatment of AIDS
-
Phillips, M.D., B. Nascimbeni, R.R. Tice and M.D. Shelby (1991) Induction of Micronuclei in Mouse Bone Marrow Cells: An Evaluation of Nucleoside Analogues used in the Treatment of AIDS, Environ. Mol. Mutagen., 18, 168-183.
-
(1991)
Environ. Mol. Mutagen.
, vol.18
, pp. 168-183
-
-
Phillips, M.D.1
Nascimbeni, B.2
Tice, R.R.3
Shelby, M.D.4
-
155
-
-
0027251049
-
Comparison of sequence preference of tomaymycin-and anthramycin-DNA bonding by exonuclease III and lambda exonuclease digestion and UvrABC nuclease incision analysis
-
Pierce, J.R., M. Nazimiec and M.S. Tang (1993) Comparison of Sequence Preference of Tomaymycin-and Anthramycin-DNA Bonding by Exonuclease III and Lambda Exonuclease Digestion and UvrABC Nuclease Incision Analysis, Biochemistry, 32, 7069-7078.
-
(1993)
Biochemistry
, vol.32
, pp. 7069-7078
-
-
Pierce, J.R.1
Nazimiec, M.2
Tang, M.S.3
-
156
-
-
0343319476
-
Fluorescence in situ hybridization with human chromosome-specific libraries: Detection of trisomy 21 and translocations of chromosome 4
-
Pinkel, D., J. Landegent, C. Collins, J. Fuscoe, R. Segraves, J. Lucas and J. Gray (1988) Fluorescence in situ Hybridization with Human Chromosome-Specific Libraries: Detection of Trisomy 21 and Translocations of Chromosome 4, Proc. Natl. Acad. Sci. USA, 85, 9138-9142.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 9138-9142
-
-
Pinkel, D.1
Landegent, J.2
Collins, C.3
Fuscoe, J.4
Segraves, R.5
Lucas, J.6
Gray, J.7
-
157
-
-
0023626977
-
Binding of hoechst 33258 to the minor groove of B-DNA
-
Pjura, P.E., K. Grzeskowiak and R.E. Dickerson (1987) Binding of Hoechst 33258 to the Minor Groove of B-DNA, J. Mol. Biol., 197, 257-271.
-
(1987)
J. Mol. Biol.
, vol.197
, pp. 257-271
-
-
Pjura, P.E.1
Grzeskowiak, K.2
Dickerson, R.E.3
-
158
-
-
0018092617
-
Initial studies on the disposition of quinolinium dibromide (NSC-176319) in mice and rats
-
Plowman, J. and R.H. Adamson (1978) Initial Studies on the Disposition of Quinolinium Dibromide (NSC-176319) in Mice and Rats, Pharmacol., 17, 61-68.
-
(1978)
Pharmacol.
, vol.17
, pp. 61-68
-
-
Plowman, J.1
Adamson, R.H.2
-
159
-
-
0025346021
-
2 phase of the cell cycle
-
2 Phase of the Cell Cycle, Cell Struct. Funct., 15, 151-157.
-
(1990)
Cell Struct. Funct.
, vol.15
, pp. 151-157
-
-
Pool, M.1
Kausch, K.2
Kohler, J.3
Haaf, T.4
Hoehn, H.5
-
160
-
-
0028263354
-
Berenil acts as a poison of eukaryotic topoisomerase II
-
Portugal, J. (1994) Berenil Acts as a Poison of Eukaryotic Topoisomerase II, FEBS Lett., 344, 136-138.
-
(1994)
FEBS Lett.
, vol.344
, pp. 136-138
-
-
Portugal, J.1
-
162
-
-
0023915860
-
Assignment of DNA binding sites for 4′,6-diamidine-2-phenylindole and bisbenzamide (hoechst 33258). A comparative footprinting study
-
Portugal, J. and M.J. Waring (1988) Assignment of DNA Binding Sites for 4′,6-Diamidine-2-Phenylindole and Bisbenzamide (Hoechst 33258). A Comparative Footprinting Study, Biochim. Biophys. Acta, 949, 158-168.
-
(1988)
Biochim. Biophys. Acta
, vol.949
, pp. 158-168
-
-
Portugal, J.1
Waring, M.J.2
-
163
-
-
0018305146
-
Effects of distamycin A on human leukocytes in vitro
-
Prantera, G., S. Pimpinelli and A. Rocchi (1979) Effects of Distamycin A on Human Leukocytes In vitro, Cytogenet. Cell. Genet., 23, 103-107.
-
(1979)
Cytogenet. Cell. Genet.
, vol.23
, pp. 103-107
-
-
Prantera, G.1
Pimpinelli, S.2
Rocchi, A.3
-
164
-
-
0019778591
-
Mammalian in vivo and in vitro cytogenetic assays: A report of the U.S. EPA's gene-tox program
-
Preston, R.J., W. Au, M.A. Bender, J.G. Brewen, A.V. Carrano, J.A. Heddle, A.F. McFee, S. Wolff and J.S. Wassom (1981) Mammalian in vivo and in vitro Cytogenetic Assays: A Report of the U.S. EPA's Gene-Tox Program, Mutation Res., 87, 143-188.
-
(1981)
Mutation Res.
, vol.87
, pp. 143-188
-
-
Preston, R.J.1
Au, W.2
Bender, M.A.3
Brewen, J.G.4
Carrano, A.V.5
Heddle, J.A.6
McFee, A.F.7
Wolff, S.8
Wassom, J.S.9
-
165
-
-
0011878020
-
Sequence selectivity in DNA-antitumour drug interactions
-
M.H. Sarma and R.H. Sarma (Eds.), Adenine Press, New York
-
Pullman, B., Sequence Selectivity in DNA-antitumour Drug Interactions. In M.H. Sarma and R.H. Sarma (Eds.), Structure And Expression (DNA and Its Drug Complexes), Vol. 2, Adenine Press, New York, 1988, pp. 237-249.
-
(1988)
Structure and Expression (DNA and Its Drug Complexes)
, vol.2
, pp. 237-249
-
-
Pullman, B.1
-
166
-
-
0025311054
-
Molecular recognition between oligopeptides and nucleic acids: DNA sequence specificity and binding properties of thiazole-lexitropsins incorporating the concepts of base site acceptance and avoidance
-
Rao, K.E., R.G. Shea, B. Yadagiri and J.W. Lown (1990) Molecular Recognition Between Oligopeptides and Nucleic Acids: DNA Sequence Specificity and Binding Properties of Thiazole-Lexitropsins Incorporating the Concepts of Base Site Acceptance and Avoidance, Anti-Cancer Drug Des., 5, 3-20.
-
(1990)
Anti-cancer Drug Des.
, vol.5
, pp. 3-20
-
-
Rao, K.E.1
Shea, R.G.2
Yadagiri, B.3
Lown, J.W.4
-
167
-
-
0022358966
-
Reaction of the antitumour antibiotic CC-1065 with DNA. Location of the site of thermally induced strand breakage and analysis of DNA sequence specificity
-
Reynolds, V.L., I.J. Molineux, D.J. Kaplan, D.H. Swenson and L.H. Hurley (1985) Reaction of the Antitumour Antibiotic CC-1065 with DNA. Location of the Site of Thermally Induced Strand Breakage and Analysis of DNA Sequence Specificity, Biochemistry, 24, 6228-6237.
-
(1985)
Biochemistry
, vol.24
, pp. 6228-6237
-
-
Reynolds, V.L.1
Molineux, I.J.2
Kaplan, D.J.3
Swenson, D.H.4
Hurley, L.H.5
-
168
-
-
0020328989
-
The effect of in vitro distamycin A exposure on metaphase chromosome structure
-
Ronne, M., F.E. Eldridge, R. Thust and O Andersen (1982) The Effect of in vitro Distamycin A Exposure on Metaphase Chromosome Structure, Hereditas, 96, 269-277.
-
(1982)
Hereditas
, vol.96
, pp. 269-277
-
-
Ronne, M.1
Eldridge, F.E.2
Thust, R.3
Andersen, O.4
-
171
-
-
0023902264
-
Therapeutic attack of hypoxic cells of solid tumours: Presidential address
-
Sartorelli, A.C. (1988) Therapeutic Attack of Hypoxic Cells of Solid Tumours: Presidential Address, Cancer Res., 48, 775-778.
-
(1988)
Cancer Res.
, vol.48
, pp. 775-778
-
-
Sartorelli, A.C.1
-
172
-
-
0028610309
-
Mitomycin C: A prototype bioreductive agent
-
Sartorelli, A.C., W.F. Hodnick, M.F. Belcourt, M. Tomasz, B. Haffty, J.J. Fischer and S. Rockwell (1994) Mitomycin C: A Prototype Bioreductive Agent, Oncol. Res., 6, 501-508.
-
(1994)
Oncol. Res.
, vol.6
, pp. 501-508
-
-
Sartorelli, A.C.1
Hodnick, W.F.2
Belcourt, M.F.3
Tomasz, M.4
Haffty, B.5
Fischer, J.J.6
Rockwell, S.7
-
173
-
-
0027905008
-
DNA repair helicase: A component of BTF2 (TFIIH) basic transcription factor
-
Schaeffer, L., R. Roy, S. Humbert, V. Moncollin, W. Vermeulen, J.H.J. Hoejimakers, P. Chambon and J.M. Egly (1993) DNA Repair Helicase: A Component of BTF2 (TFIIH) Basic Transcription Factor, Science, 260, 58-63.
-
(1993)
Science
, vol.260
, pp. 58-63
-
-
Schaeffer, L.1
Roy, R.2
Humbert, S.3
Moncollin, V.4
Vermeulen, W.5
Hoejimakers, J.H.J.6
Chambon, P.7
Egly, J.M.8
-
174
-
-
0023615931
-
The fragile site (17)(p12): Induction by AT-specific DNA-ligands and population cytogenetics
-
Schmid, M., W. Feichtinger, C. Deubelbeiss and E. Weller (1987) The Fragile Site (17)(p12): Induction by AT-specific DNA-Ligands and Population Cytogenetics, Hum. Genet., 77, 118-121.
-
(1987)
Hum. Genet.
, vol.77
, pp. 118-121
-
-
Schmid, M.1
Feichtinger, W.2
Deubelbeiss, C.3
Weller, E.4
-
175
-
-
0018098983
-
Mutagenicity of several classes of antitumor agents to Salmonella typhimurium TA98, TA100 and TA92
-
Seino, Y., M. Nagao, T. Yahagi, A. Hoshi, T. Kawachi and T. Sugimura (1978) Mutagenicity of Several Classes of Antitumor Agents to Salmonella typhimurium TA98, TA100 and TA92, Cancer Res., 38, 2148-2156.
-
(1978)
Cancer Res.
, vol.38
, pp. 2148-2156
-
-
Seino, Y.1
Nagao, M.2
Yahagi, T.3
Hoshi, A.4
Kawachi, T.5
Sugimura, T.6
-
176
-
-
0024293248
-
ABC excinuclease incises both 5′ and 3′ to the CC-1065-DNA adduct and its incision activity is stimulated by DNA helicase II and DNA polymerase I
-
Selby, C.P. and A. Sancar (1988) ABC Excinuclease Incises both 5′ and 3′ to the CC-1065-DNA Adduct and Its Incision Activity is Stimulated by DNA Helicase II and DNA Polymerase I, Biochemistry, 27, 7184-7188.
-
(1988)
Biochemistry
, vol.27
, pp. 7184-7188
-
-
Selby, C.P.1
Sancar, A.2
-
177
-
-
0025858687
-
Noncovalent drug-DNA binding interactions that inhibit and stimulate (A)BC excinuclease
-
Selby, C.P. and A. Sancar (1991) Noncovalent Drug-DNA Binding Interactions That Inhibit and Stimulate (A)BC Excinuclease, Biochemistry, 30, 3841-3849.
-
(1991)
Biochemistry
, vol.30
, pp. 3841-3849
-
-
Selby, C.P.1
Sancar, A.2
-
178
-
-
0027905034
-
Molecular mechanism of transcription-repair coupling
-
Selby, C.P. and A. Sancar (1993) Molecular Mechanism of Transcription-Repair Coupling, Science, 260, 53-58.
-
(1993)
Science
, vol.260
, pp. 53-58
-
-
Selby, C.P.1
Sancar, A.2
-
179
-
-
0028597070
-
Phase I study of the novel distamycin derivative tallimustine (FCE 24517)
-
Sessa, C., O. Pagani, M.G. Zurlo, J. de-Jong, C. Hofmann, M. Lassus, P. Marrari, M. Strolin-Benedetti and F. Cavalli (1994) Phase I Study of the Novel Distamycin Derivative Tallimustine (FCE 24517), Ann. Oncol., 5, 901-907.
-
(1994)
Ann. Oncol.
, vol.5
, pp. 901-907
-
-
Sessa, C.1
Pagani, O.2
Zurlo, M.G.3
De-Jong, J.4
Hofmann, C.5
Lassus, M.6
Marrari, P.7
Strolin-Benedetti, M.8
Cavalli, F.9
-
180
-
-
0028082283
-
Phase I study of adozelesin (U-73,975) in patients with solid tumors
-
Shamdas, G.J., D.S. Alberts, M. Modiano, C. Wiggins, J. Power, D.A. Kasunic, G.L. Elfring and R.H. Earhart (1994) Phase I Study of Adozelesin (U-73,975) in Patients With Solid Tumors, Anticancer. Drugs., 5, 10-14.
-
(1994)
Anticancer. Drugs.
, vol.5
, pp. 10-14
-
-
Shamdas, G.J.1
Alberts, D.S.2
Modiano, M.3
Wiggins, C.4
Power, J.5
Kasunic, D.A.6
Elfring, G.L.7
Earhart, R.H.8
-
181
-
-
0025688249
-
Metabolism of mitomycin C by DT-diaphorase: Role in mitomycin C induced DNA damage and cytotoxicity in human colon carcinoma cells
-
Siegel, D., N.W. Gibson, P.C. Preusch and D. Ross (1990) Metabolism of Mitomycin C by DT-Diaphorase: Role in Mitomycin C Induced DNA Damage and Cytotoxicity in Human Colon Carcinoma Cells, Cancer Res., 50, 7483-7489.
-
(1990)
Cancer Res.
, vol.50
, pp. 7483-7489
-
-
Siegel, D.1
Gibson, N.W.2
Preusch, P.C.3
Ross, D.4
-
182
-
-
0025261213
-
Involvement of DNA topoisomerase II in the selective resistance of a mammalian cell mutant to DNA minor groove ligands: Ligand-induced DNA-protein crosslinking and responses to topoisomerase poisons
-
Smith, P.J., S.M. Bell, A. Dee and H. Sykes (1990) Involvement of DNA Topoisomerase II in the Selective Resistance of a Mammalian Cell Mutant to DNA Minor Groove Ligands: Ligand-induced DNA-protein Crosslinking and Responses to Topoisomerase Poisons, Carcinogenesis, 11, 659-665.
-
(1990)
Carcinogenesis
, vol.11
, pp. 659-665
-
-
Smith, P.J.1
Bell, S.M.2
Dee, A.3
Sykes, H.4
-
184
-
-
0003530492
-
Characterization of the AS52 cell line for use in mammalian cell mutagenesis studies
-
M.M. Moore, D.M. Demarini, F.J. De Serres and K.R. Tindall (Eds.), Cold Spring Harbour Laboratory, New York
-
Stankowski Jr., L.F. and K.R. Tindall, Characterization of the AS52 Cell Line for Use in Mammalian Cell Mutagenesis Studies. In M.M. Moore, D.M. Demarini, F.J. De Serres and K.R. Tindall (Eds.), Mammalian Cell Mutagenesis, Cold Spring Harbour Laboratory, New York, 1987, pp. 71-79.
-
(1987)
Mammalian Cell Mutagenesis
, pp. 71-79
-
-
Stankowski L.F., Jr.1
Tindall, K.R.2
-
185
-
-
0026457950
-
Multistep carcinogenesis: A 1992 perspective
-
Sugimura, T. (1992) Multistep Carcinogenesis: A 1992 Perspective, Science, 258, 603-607.
-
(1992)
Science
, vol.258
, pp. 603-607
-
-
Sugimura, T.1
-
186
-
-
0026572090
-
Effect of the (+)-CC-1065-(N3-adenine)DNA adduct on in vitro DNA synthesis mediated by escherichia coli DNA polymerase
-
Sun, D. and L.H. Hurley (1992a) Effect of the (+)-CC-1065-(N3-adenine)DNA Adduct on in vitro DNA Synthesis Mediated by Escherichia coli DNA Polymerase, Biochemistry, 31, 2822-2829.
-
(1992)
Biochemistry
, vol.31
, pp. 2822-2829
-
-
Sun, D.1
Hurley, L.H.2
-
187
-
-
0026598785
-
Inhibition of T4 DNA ligase activity by (+)-CC-1065: Demonstration of the importance of the stiffening and winding effects of (+)-CC-1065 on DNA
-
Sun, D. and L.H. Hurley (1992b) Inhibition of T4 DNA Ligase Activity by (+)-CC-1065: Demonstration of the Importance of the Stiffening and Winding Effects of (+)-CC-1065 on DNA, Anti-Cancer Drug Des., 7, 15-36.
-
(1992)
Anti-cancer Drug Des.
, vol.7
, pp. 15-36
-
-
Sun, D.1
Hurley, L.H.2
-
188
-
-
0027483691
-
Transcription-coupled DNA repair
-
Sweder, K.S. and P.C. Hanawalt (1993) Transcription-coupled DNA Repair, Science, 262, 439.
-
(1993)
Science
, vol.262
, pp. 439
-
-
Sweder, K.S.1
Hanawalt, P.C.2
-
189
-
-
0027219319
-
Molecular structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor groove binding drug netropsin
-
Tabernero, L., N. Verdaguer, M. Coll, I. Fita, G.A. van-der-Marel, J.H. van-Boom, A. Rich and J. Aymami (1993) Molecular Structure of the A-tract DNA Dodecamer d(CGCAAATTTGCG) Complexed with the Minor Groove Binding Drug Netropsin, Biochemistry, 32, 8403-8410.
-
(1993)
Biochemistry
, vol.32
, pp. 8403-8410
-
-
Tabernero, L.1
Verdaguer, N.2
Coll, M.3
Fita, I.4
Van-Der-Marel, G.A.5
Van-Boom, J.H.6
Rich, A.7
Aymami, J.8
-
190
-
-
0017276429
-
Neothramycins A and B, new antitumour antibiotics
-
Takeuchi, T., M. Miyamoto, M. Ishizuka, H. Naganawa, S. Kondo, M. Hamada and H. Umezawa (1976) Neothramycins A and B, New Antitumour Antibiotics, J. Antibiot., 29, 93-96.
-
(1976)
J. Antibiot.
, vol.29
, pp. 93-96
-
-
Takeuchi, T.1
Miyamoto, M.2
Ishizuka, M.3
Naganawa, H.4
Kondo, S.5
Hamada, M.6
Umezawa, H.7
-
191
-
-
0023846687
-
Recognition and repair of the CC-1065-(N3-adenine)-DNA adduct by the UVRABC nucleases
-
Tang, M-S., C.-S. Lee, R. Doisy, L. Ross, D.R. Needham-VanDevanter and L.H. Hurley (1988) Recognition and Repair of the CC-1065-(N3-Adenine)-DNA Adduct by the UVRABC Nucleases, Biochemistry, 27, 893-901.
-
(1988)
Biochemistry
, vol.27
, pp. 893-901
-
-
Tang, M.-S.1
Lee, C.-S.2
Doisy, R.3
Ross, L.4
Needham-VanDevanter, D.R.5
Hurley, L.H.6
-
192
-
-
0028270470
-
Formation and repair of antitumor antibiotic CC-1065-induced DNA adducts in the adenine phosphoribosyltransferase and amplified dihydrofolate reductase genes of Chinese hamster ovary cells
-
Tang, M.S., M. Qian and A. Pao (1994) Formation and Repair of Antitumor Antibiotic CC-1065-induced DNA Adducts in the Adenine Phosphoribosyltransferase and Amplified Dihydrofolate Reductase Genes of Chinese Hamster Ovary Cells, Biochemistry, 33, 2726-2732.
-
(1994)
Biochemistry
, vol.33
, pp. 2726-2732
-
-
Tang, M.S.1
Qian, M.2
Pao, A.3
-
193
-
-
0028231729
-
Fully automated high-performance liquid chromatographic method for the determination of carzelesin (U-80,244) and metabolites (U-76,073 and U-76,074) in human plasma
-
van-Tellingen, O., E.M. Pels, R.E. Henrar, L.J. Schaaf, G.E. Padbury, J.H. Beijnen and W.J. Nooijen (1994) Fully Automated High-performance Liquid Chromatographic Method for the Determination of Carzelesin (U-80,244) and Metabolites (U-76,073 and U-76,074) in Human Plasma, J. Chromatogr., 652, 51-58.
-
(1994)
J. Chromatogr.
, vol.652
, pp. 51-58
-
-
Van-Tellingen, O.1
Pels, E.M.2
Henrar, R.E.3
Schaaf, L.J.4
Padbury, G.E.5
Beijnen, J.H.6
Nooijen, W.J.7
-
194
-
-
0000290648
-
Refuin: A non-cytotoxic carcinostatic compound proliferated by a thermophilic actinomycete
-
Tendler, M.D. and S. Korman (1963) Refuin: A Non-cytotoxic Carcinostatic Compound Proliferated by a Thermophilic Actinomycete, Nature, 199, 501.
-
(1963)
Nature
, vol.199
, pp. 501
-
-
Tendler, M.D.1
Korman, S.2
-
195
-
-
0025736111
-
New insights in DNA repair: Preferential repair of transcriptionally active DNA
-
Terleth, C., P. Van de Putte and J. Brouwer (1991) New Insights in DNA Repair: Preferential Repair of Transcriptionally Active DNA, Mutagenesis, 6, 103-111.
-
(1991)
Mutagenesis
, vol.6
, pp. 103-111
-
-
Terleth, C.1
Van De Putte, P.2
Brouwer, J.3
-
196
-
-
0019518921
-
Structural modifications induced in Chinese hamster V79-E chromosomes by prfixation treatment in vitro with the AT-specific agents netropsin, distamycin A, and hoechst33258
-
Thust, R. and M. Ronne (1981) Structural Modifications Induced in Chinese Hamster V79-E Chromosomes by Prfixation Treatment In vitro with the AT-Specific Agents Netropsin, Distamycin A, and Hoechst33258, Hereditas, 94, 209-213.
-
(1981)
Hereditas
, vol.94
, pp. 209-213
-
-
Thust, R.1
Ronne, M.2
-
197
-
-
0020327270
-
Localisation of SCEs and their possible relationship to dA.dT-or dG · dC-Clusters, respectively in Chinese hamster V79-E chromosomes
-
Thust, R. and M. Ronne (1982) Localisation of SCEs and their Possible Relationship to dA.dT-or dG · dC-Clusters, Respectively in Chinese Hamster V79-E Chromosomes, Hereditas, 96, 295-298.
-
(1982)
Hereditas
, vol.96
, pp. 295-298
-
-
Thust, R.1
Ronne, M.2
-
198
-
-
0025238627
-
Analogues of 1,5-Bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental pneumocystis carinii pneumonia
-
Tidwell, R.R., S.K. Jones, J.D. Geratz, K.A. Ohemeng, M. Cory and J.E. Hall (1990) Analogues of 1,5-Bis(4-amidinophenoxy)pentane (Pentamidine) in the Treatment of Experimental Pneumocystis carinii Pneumonia, J. Med. Chem., 33, 1252-1257.
-
(1990)
J. Med. Chem.
, vol.33
, pp. 1252-1257
-
-
Tidwell, R.R.1
Jones, S.K.2
Geratz, J.D.3
Ohemeng, K.A.4
Cory, M.5
Hall, J.E.6
-
199
-
-
0011871108
-
Deletion mutations are associated with the differential-induced mutant frequency response of the AS52 and CHO-K1-BH4 cell lines
-
M.M. Moore, D.M. Demarini, F.J. de Serres and K.R. Tindall (Eds.), Cold Spring Harbour Laboratory, New York
-
Tindall, K.R. and L.F. Stankowski Jr., Deletion Mutations are Associated with the Differential-induced Mutant Frequency Response of the AS52 and CHO-K1-BH4 Cell Lines. In M.M. Moore, D.M. Demarini, F.J. de Serres and K.R. Tindall (Eds.), Mammalian Cell Mutagenesis, Cold Spring Harbour Laboratory, New York, 1987, pp. 283-292.
-
(1987)
Mammalian Cell Mutagenesis
, pp. 283-292
-
-
Tindall, K.R.1
Stankowski L.F., Jr.2
-
200
-
-
0023123806
-
Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA
-
Tomasz, M.R., R. Lipman, D. Chowdry, J. Pawlak, G.L. Verdine and K. Nakanishi (1987) Isolation and Structure of a Covalent Cross-link Adduct Between Mitomycin C and DNA, Science, 235, 1204.
-
(1987)
Science
, vol.235
, pp. 1204
-
-
Tomasz, M.R.1
Lipman, R.2
Chowdry, D.3
Pawlak, J.4
Verdine, G.L.5
Nakanishi, K.6
-
201
-
-
0022970672
-
The treatment of bladder cancer by neothramycin
-
Tsugaya, M., H. Washida, N. Hirao, Y. Hachisuka, H. Sakagami and Y. Iwase (1986) The Treatment of Bladder Cancer by Neothramycin, Hinyokika, Kiyo., 32, 1443-1448.
-
(1986)
Hinyokika, Kiyo.
, vol.32
, pp. 1443-1448
-
-
Tsugaya, M.1
Washida, H.2
Hirao, N.3
Hachisuka, Y.4
Sakagami, H.5
Iwase, Y.6
-
202
-
-
0025346326
-
The micronucleus assay as a test for the detection of aneugenic activity
-
Vanparys, P., F. Vermeiren, M. Sysmans and R. Temmerman (1990) The Micronucleus Assay as a Test for the Detection of Aneugenic Activity, Mutation Res., 244, 95-103.
-
(1990)
Mutation Res.
, vol.244
, pp. 95-103
-
-
Vanparys, P.1
Vermeiren, F.2
Sysmans, M.3
Temmerman, R.4
-
203
-
-
0018697844
-
Anthramycin-induced sister-chromatid exchange and caffeine potentiation in the chromosomes of indian muntjac
-
Ved-Brat, S., R.S. Verma and H. Dosik (1979) Anthramycin-induced Sister-chromatid Exchange and Caffeine Potentiation in the Chromosomes of Indian Muntjac, Mutation Res., 63, 325-334.
-
(1979)
Mutation Res.
, vol.63
, pp. 325-334
-
-
Ved-Brat, S.1
Verma, R.S.2
Dosik, H.3
-
204
-
-
0028657069
-
Clinical studies with EO9, a new indoloquinone bioreductive alkylating cytotoxic agent
-
Verweij, J., S. Aamadal, J. Schellens, I. Koier and B. Lund (1994) Clinical Studies with EO9, A New Indoloquinone Bioreductive Alkylating Cytotoxic Agent, Oncol. Res., 6, 519-523.
-
(1994)
Oncol. Res.
, vol.6
, pp. 519-523
-
-
Verweij, J.1
Aamadal, S.2
Schellens, J.3
Koier, I.4
Lund, B.5
-
205
-
-
0022897382
-
Sequence of centromere separation: Kinetochore formation in induced laggards and micronuclei
-
Vig, B.K. and S.E. Swearngin (1986) Sequence of Centromere Separation: Kinetochore Formation in Induced Laggards and Micronuclei, Mutagenesis, 1, 461-465.
-
(1986)
Mutagenesis
, vol.1
, pp. 461-465
-
-
Vig, B.K.1
Swearngin, S.E.2
-
206
-
-
0028361852
-
Preclinical pharmacology of bizelesin, a potent bifunctional analog of the DNA-binding antibiotic CC-1065
-
Walker, D.L., J.M. Reid and M.M. Ames (1994) Preclinical Pharmacology of Bizelesin, a Potent Bifunctional Analog of the DNA-binding Antibiotic CC-1065, Cancer Chemother. Pharmacol., 34, 317-322.
-
(1994)
Cancer Chemother. Pharmacol.
, vol.34
, pp. 317-322
-
-
Walker, D.L.1
Reid, J.M.2
Ames, M.M.3
-
207
-
-
0023709378
-
Recognition of the DNA helix stabilising anthramycin-N2 guanine adduct by UVRABC nuclease
-
Walter, R.B., J. Pierce, R. Case and M.-S. Tang (1988) Recognition of the DNA Helix Stabilising Anthramycin-N2 Guanine Adduct by UVRABC Nuclease, J. Mol. Biol., 203, 939-947.
-
(1988)
J. Mol. Biol.
, vol.203
, pp. 939-947
-
-
Walter, R.B.1
Pierce, J.2
Case, R.3
Tang, M.-S.4
-
208
-
-
0026637636
-
Anti-HIV-I activity of linked lexitropsins
-
Wang, W. and J.W. Lown (1992) Anti-HIV-I Activity of Linked Lexitropsins, J. Med. Chem., 35, 2890-2897.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 2890-2897
-
-
Wang, W.1
Lown, J.W.2
-
209
-
-
0028275002
-
Synthesis, DNA binding, sequence preference and biological evaluation of minor groove-selective N1-alkoxyalkyl-bis-benzimidazoles
-
Wang, H., R. Gupta and J.W. Lown (1994) Synthesis, DNA Binding, Sequence Preference and Biological Evaluation of Minor Groove-Selective N1-alkoxyalkyl-bis-benzimidazoles, Anti-Cancer Drug Des., 9, 153-180.
-
(1994)
Anti-Cancer Drug Des.
, vol.9
, pp. 153-180
-
-
Wang, H.1
Gupta, R.2
Lown, J.W.3
-
210
-
-
0023769588
-
The origins of human cancer: Molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment-twenty-seventh G.H.A. Clowes memorial award lecture
-
Weinstein, I.B. (1988) The Origins of Human Cancer: Molecular Mechanisms of Carcinogenesis and Their Implications for Cancer Prevention and Treatment-Twenty-Seventh G.H.A. Clowes Memorial Award Lecture, Cancer Res., 48, 4135-4143.
-
(1988)
Cancer Res.
, vol.48
, pp. 4135-4143
-
-
Weinstein, I.B.1
-
211
-
-
0025331934
-
Leukemia and cancer chemotherapy
-
Williams, C.J. (1990) Leukemia and Cancer Chemotherapy, Br. Med. J., 301, 73-74.
-
(1990)
Br. Med. J.
, vol.301
, pp. 73-74
-
-
Williams, C.J.1
-
212
-
-
0028296397
-
Transcriptional regulation of differentiation, selective toxicity and ATGCAAAT binding of bisbenzimidazole derivatives in human melanoma cells
-
Wong, S.S.C., R.A. Sturm, J. Michel, X.M. Zhang, P.A.C. Danoy, K. McGregor, J.J. Jacobs, A. Kaushal, Y. Dong, I.S. Dunn and P.G. Parsons (1994) Transcriptional Regulation of Differentiation, Selective Toxicity and ATGCAAAT Binding of Bisbenzimidazole Derivatives in Human Melanoma Cells, Biochem. Pharmacol., 47, 827-837.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 827-837
-
-
Wong, S.S.C.1
Sturm, R.A.2
Michel, J.3
Zhang, X.M.4
Danoy, P.A.C.5
McGregor, K.6
Jacobs, J.J.7
Kaushal, A.8
Dong, Y.9
Dunn, I.S.10
Parsons, P.G.11
-
213
-
-
0025306995
-
DNA breaks and repair in the mouse leukemia L1210 cells exposed to three different types of interstrand DNA cross-linkers
-
Yajima, N.. S. Hochi, N. Miyata, T. Kishi and G. Kawanishi (1990) DNA Breaks and Repair in the Mouse Leukemia L1210 Cells Exposed to Three Different Types of Interstrand DNA Cross-Linkers, Mutation Res., 236, 43-50.
-
(1990)
Mutation Res.
, vol.236
, pp. 43-50
-
-
Yajima, N.1
Hochi, S.2
Miyata, N.3
Kishi, T.4
Kawanishi, G.5
-
214
-
-
0011805657
-
The phthalanilides
-
A.C. Sartorelli and D.G. Johns (Eds.), Springer-Verlag, New York
-
Yesair, D.W. and C.J. Kensler, The Phthalanilides. In A.C. Sartorelli and D.G. Johns (Eds.), Antineoplastic and Immunosuppressive Agents, Vol. 2, Springer-Verlag, New York, 1975, pp. 820-828.
-
(1975)
Antineoplastic and Immunosuppressive Agents
, vol.2
, pp. 820-828
-
-
Yesair, D.W.1
Kensler, C.J.2
-
215
-
-
0027237479
-
Groove and sequence-selective alkylation of DNA by sulfonate esters tethered to lexitropsins
-
Zhang, Y., F.X. Chen, P. Mehta and B. Gold (1993) Groove and Sequence-selective Alkylation of DNA by Sulfonate Esters Tethered to Lexitropsins, Biochemistry, 32, 7954-7965.
-
(1993)
Biochemistry
, vol.32
, pp. 7954-7965
-
-
Zhang, Y.1
Chen, F.X.2
Mehta, P.3
Gold, B.4
-
216
-
-
0038840492
-
The molecular mechanism of interaction of non-intercalative groove binding antitumour drugs with DNA
-
Zimmer, C., G. Luck, G. Burckhardt, K. Krowicki and J.W. Lown (1986) The Molecular Mechanism of Interaction of Non-intercalative Groove Binding Antitumour Drugs with DNA, Pont. Acad. Scienti. Scripta Varia, 70, 339-363.
-
(1986)
Pont. Acad. Scienti. Scripta Varia
, vol.70
, pp. 339-363
-
-
Zimmer, C.1
Luck, G.2
Burckhardt, G.3
Krowicki, K.4
Lown, J.W.5
-
217
-
-
0021267081
-
Testing of chemicals for genetic activity with saccharomyces cerevisiae: A report of the U.S. EPA gene-tox program
-
Zimmerman, F.K., R.C. von Borstel, E.S. von Halle, J.M. Parry, D. Siebert, G. Zetterberg, R. Barale and N. Loprieno (1984) Testing of Chemicals for Genetic Activity with Saccharomyces cerevisiae: A Report of the U.S. EPA Gene-Tox Program, Mutation Res., 133, 199-244.
-
(1984)
Mutation Res.
, vol.133
, pp. 199-244
-
-
Zimmerman, F.K.1
Von Borstel, R.C.2
Von Halle, E.S.3
Parry, J.M.4
Siebert, D.5
Zetterberg, G.6
Barale, R.7
Loprieno, N.8
-
218
-
-
0025947456
-
Polyploid induction as a consequence of topoisomerase inhibition
-
Zucker, R.M., D.J. Adams, K.W. Bair and K.H. Elstein (1991) Polyploid Induction as a Consequence of Topoisomerase Inhibition, Biochem. Pharmacol., 42, 2199-2208.
-
(1991)
Biochem. Pharmacol.
, vol.42
, pp. 2199-2208
-
-
Zucker, R.M.1
Adams, D.J.2
Bair, K.W.3
Elstein, K.H.4
|