메뉴 건너뛰기




Volumn 403, Issue 6769, 2000, Pages 544-549

Motor disorder in Huntington's disease begins as a dysfunction in error feedback control

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CLINICAL FEATURE; FEEDBACK SYSTEM; GENETIC ANALYSIS; HUMAN; HUNTINGTON CHOREA; MOTOR CONTROL; MOTOR NERVE CONDUCTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

EID: 0034598808     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35000576     Document Type: Article
Times cited : (299)

References (29)
  • 2
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72, 971-983 (1993).
    • (1993) Cell , vol.72 , pp. 971-983
  • 3
    • 0031037349 scopus 로고    scopus 로고
    • Longitudinal change in basal ganglia volume in patients with Huntington's disease
    • Aylward, E. H. et al. Longitudinal change in basal ganglia volume in patients with Huntington's disease. Neurology 48, 394-399 (1997).
    • (1997) Neurology , vol.48 , pp. 394-399
    • Aylward, E.H.1
  • 4
    • 0030447557 scopus 로고    scopus 로고
    • Basal ganglia volume and proximity to onset in presymptomatic Huntington disease
    • Aylward, E. H. et al. Basal ganglia volume and proximity to onset in presymptomatic Huntington disease. Arch Neurol. 53, 1293-1296 (1996).
    • (1996) Arch Neurol. , vol.53 , pp. 1293-1296
    • Aylward, E.H.1
  • 5
    • 0021722327 scopus 로고
    • Clinical correlates of dementia and disability in Huntington's disease
    • Brandt, J. et al. Clinical correlates of dementia and disability in Huntington's disease. J. Clin. Neuropsychol. 6, 401-412 (1984).
    • (1984) J. Clin. Neuropsychol. , vol.6 , pp. 401-412
    • Brandt, J.1
  • 6
    • 0028270380 scopus 로고
    • Adaptive representation of dynamics during learning of a motor task
    • Shadmehr, R. & Mussa-Ivaldi, F. A. Adaptive representation of dynamics during learning of a motor task. J. Neurosci. 14, 3208-3224 (1994).
    • (1994) J. Neurosci. , vol.14 , pp. 3208-3224
    • Shadmehr, R.1    Mussa-Ivaldi, F.A.2
  • 7
    • 0027488969 scopus 로고
    • Inverse-dynamics model eye movement control by Purkinje cells in the cerebellum
    • Shidara, M., Kawano, K., Gomi, H. & Kawato, M. Inverse-dynamics model eye movement control by Purkinje cells in the cerebellum. Nature 365, 50-52 (1993).
    • (1993) Nature , vol.365 , pp. 50-52
    • Shidara, M.1    Kawano, K.2    Gomi, H.3    Kawato, M.4
  • 8
    • 0033162942 scopus 로고    scopus 로고
    • Computational nature of human adaptive control during learning of reaching movements in force fields
    • Bhushan, N. & Shadmehr, R. Computational nature of human adaptive control during learning of reaching movements in force fields. Biol. Cybern. 81, 39-60 (1999).
    • (1999) Biol. Cybern. , vol.81 , pp. 39-60
    • Bhushan, N.1    Shadmehr, R.2
  • 9
    • 0031022919 scopus 로고    scopus 로고
    • Functional stages in the formation of human long-term motor memory
    • Shadmehr, R. & Brashers-Krug, T. Functional stages in the formation of human long-term motor memory. J. Neurosci. 17, 409-419 (1997).
    • (1997) J. Neurosci. , vol.17 , pp. 409-419
    • Shadmehr, R.1    Brashers-Krug, T.2
  • 10
    • 0022417008 scopus 로고
    • The coordination of arm movements: An experimentally confirmed mathematical model
    • Flash, T. & Hogan, N. The coordination of arm movements: an experimentally confirmed mathematical model. J. Neurosci, 5, 1688-1703 (1985).
    • (1985) J. Neurosci , vol.5 , pp. 1688-1703
    • Flash, T.1    Hogan, N.2
  • 11
    • 0022474508 scopus 로고
    • Manual tracking of visual targets by trained monkeys
    • Miall, R. C., Weir, D. J. & Stein, J. F. Manual tracking of visual targets by trained monkeys. Behav. Brain Res. 20, 185-201 (1986).
    • (1986) Behav. Brain Res. , vol.20 , pp. 185-201
    • Miall, R.C.1    Weir, D.J.2    Stein, J.F.3
  • 12
    • 0028964255 scopus 로고
    • Are arm trajectories planned in kinematic or dynamic coordinates? An adaptation study
    • Wolpert, D. M., Ghahramani, Z. & Jordan, M. I. Are arm trajectories planned in kinematic or dynamic coordinates? An adaptation study. Exp. Brain Res. 103, 460-470 (1995).
    • (1995) Exp. Brain Res. , vol.103 , pp. 460-470
    • Wolpert, D.M.1    Ghahramani, Z.2    Jordan, M.I.3
  • 13
    • 0025098759 scopus 로고
    • Kinesthetic control of a multijoint movement sequence
    • Cordo, P. J. Kinesthetic control of a multijoint movement sequence. J. Neurophysiol. 63, 161-172 (1990).
    • (1990) J. Neurophysiol. , vol.63 , pp. 161-172
    • Cordo, P.J.1
  • 14
    • 0022115986 scopus 로고
    • Kinematic features of unrestrained vertical arm movements
    • Atkeson, C. G. & Hollerbach, J. M. Kinematic features of unrestrained vertical arm movements. J. Neurosci. 59, 2318-2330 (1985).
    • (1985) J. Neurosci. , vol.59 , pp. 2318-2330
    • Atkeson, C.G.1    Hollerbach, J.M.2
  • 15
    • 0026725551 scopus 로고
    • Motor responses evoked by magnetic brain stimulation in Huntington's disease
    • Meyer, B. U. et at. Motor responses evoked by magnetic brain stimulation in Huntington's Disease. Electroencephalogr Clin. Neurophysiol. 85, 197-208 (1992).
    • (1992) Electroencephalogr Clin. Neurophysiol. , vol.85 , pp. 197-208
    • Meyer, B.U.1
  • 16
    • 0021946101 scopus 로고
    • Long-loop reflexes in small hand muscles studied in normal subjects and in patients with Huntington's disease
    • Noth, J., Podoll, K. & Friedemann, H. H. Long-loop reflexes in small hand muscles studied in normal subjects and in patients with Huntington's Disease. Brain 108, 65-80 (1985).
    • (1985) Brain , vol.108 , pp. 65-80
    • Noth, J.1    Podoll, K.2    Friedemann, H.H.3
  • 17
    • 0027388933 scopus 로고
    • Comparison of somatosensory evoked potentials with striatal glucose consumption measured by positron emission tomography in the early diagnosis of Huntington's disease
    • Kuwert, T. et al. Comparison of somatosensory evoked potentials with striatal glucose consumption measured by positron emission tomography in the early diagnosis of Huntington's Disease. Mov. Disord. 8, 98-106 (1993).
    • (1993) Mov. Disord. , vol.8 , pp. 98-106
    • Kuwert, T.1
  • 18
    • 0027401152 scopus 로고
    • Absence of frontal somatosensory evoked potentials in Huntington's disease
    • Topper, R., Schwarz, M., Podoll, K., Domges, F. & Noth, J. Absence of frontal somatosensory evoked potentials in Huntington's Disease. Brain 116, 87-101 (1993).
    • (1993) Brain , vol.116 , pp. 87-101
    • Topper, R.1    Schwarz, M.2    Podoll, K.3    Domges, F.4    Noth, J.5
  • 19
    • 0029006808 scopus 로고
    • Cognitive scores in carriers of Huntington's disease gene compared to noncarriers
    • Foroud, T. et al. Cognitive scores in carriers of Huntington's disease gene compared to noncarriers. Ann. Neurol. 37, 657-664 (1995).
    • (1995) Ann. Neurol. , vol.37 , pp. 657-664
    • Foroud, T.1
  • 20
    • 0030782259 scopus 로고    scopus 로고
    • Early cognitive and motor symptoms in identified carriers of the gene for Huntington disease
    • de Boo, G. M. et al. Early cognitive and motor symptoms in identified carriers of the gene for Huntington disease. Arch. Neurol. 54, 1353-1357 (1997).
    • (1997) Arch. Neurol. , vol.54 , pp. 1353-1357
    • De Boo, G.M.1
  • 21
    • 0029977215 scopus 로고    scopus 로고
    • Motor changes in presymptomatic Huntington disease gene carriers
    • Siemers, E. et al. Motor changes in presymptomatic Huntington disease gene carriers. Arch. Neurol. 53, 487-492 (1996).
    • (1996) Arch. Neurol. , vol.53 , pp. 487-492
    • Siemers, E.1
  • 22
    • 0027185096 scopus 로고
    • Unimpaired verbal memory and oculomotor control in asymptomatic adults with the genetic marker for Huntington's disease
    • Rothlind, J. C., Brandt, J., Zee, D., Codori, A. M. & Folstein, S. Unimpaired verbal memory and oculomotor control in asymptomatic adults with the genetic marker for Huntington's disease. Arch. Neurol. 50, 799-802 (1993).
    • (1993) Arch. Neurol. , vol.50 , pp. 799-802
    • Rothlind, J.C.1    Brandt, J.2    Zee, D.3    Codori, A.M.4    Folstein, S.5
  • 23
    • 0029059308 scopus 로고
    • Cognitive performance in UK sample of presymptomatic people carrying the gene for Huntington's disease
    • Blackmore, L., Simpson, S. A. & Crawford, J. R. Cognitive performance in UK sample of presymptomatic people carrying the gene for Huntington's disease. J. Med. Genet. 32, 358-362 (1995).
    • (1995) J. Med. Genet. , vol.32 , pp. 358-362
    • Blackmore, L.1    Simpson, S.A.2    Crawford, J.R.3
  • 24
    • 0027441163 scopus 로고
    • Striatal glucose consumption in chorea-free subjects at risk of Huntington's disease
    • Kuwert, T. et al. Striatal glucose consumption in chorea-free subjects at risk of Huntington's disease. J. Neurol. 241, 31-36 (1993).
    • (1993) J. Neurol. , vol.241 , pp. 31-36
    • Kuwert, T.1
  • 25
    • 0023147905 scopus 로고
    • Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's disease
    • Mazziotta, J. C. et al. Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's Disease. N. Engl. J. Med. 316, 357-362 (1987).
    • (1987) N. Engl. J. Med. , vol.316 , pp. 357-362
    • Mazziotta, J.C.1
  • 26
    • 0030967339 scopus 로고    scopus 로고
    • Intact mirror-tracing and impaired rotary-pursuit kill learning in patients with Huntingion's disease: Evidence for dissociable memory systems in skill learning
    • Gabrieli, J. D., Stebbins, G. T., Singh, J. Willingham, D. B. & Goetz, C. G. Intact mirror-tracing and impaired rotary-pursuit kill learning in patients with Huntingion's Disease: Evidence for dissociable memory systems in skill learning. Neuropsychology 11, 272-281 (1997).
    • (1997) Neuropsychology , vol.11 , pp. 272-281
    • Gabrieli, J.D.1    Stebbins, G.T.2    Singh, J.3    Willingham, D.B.4    Goetz, C.G.5
  • 27
    • 0003435427 scopus 로고
    • Winters, J. M. & Woo, S. L. Y. Springer, New York
    • Hogan, N. in Multiple Muscle Systems (eds Winters, J. M. & Woo, S. L. Y.) 149-164 (Springer, New York, 1990).
    • (1990) Multiple Muscle Systems , pp. 149-164
    • Hogan, N.1
  • 28
    • 0030296794 scopus 로고    scopus 로고
    • Forward models for physiologic motor control
    • Miall, R. C. & Wolpert, D. M. Forward models for physiologic motor control. Neur. net. 9, 1265-1279 (1996)
    • (1996) Neur. Net. , vol.9 , pp. 1265-1279
    • Miall, R.C.1    Wolpert, D.M.2
  • 29
    • 0030896968 scopus 로고    scopus 로고
    • A neural substrate of prediction and reward
    • Schultz, W., Dayan, P. & Montague, P. R. A neural substrate of prediction and reward. Science 275, 1593-1599 (1997).
    • (1997) Science , vol.275 , pp. 1593-1599
    • Schultz, W.1    Dayan, P.2    Montague, P.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.