Early cognitive and motor symptoms in identified carriers of the gene for Huntington disease

Archives of Neurology

Volumn 54, Issue 11, 1997, Pages 1353-1357

  De Boo, Gerly M ^a,b   Tibben, Aad ^b   Lanser, Jan B K ^a   Jennekens Schinkel, Aag ^a,c   Hermans, Jo ^a   Maat Kievit, Anneke ^a   Roos, Raymund A C ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; GENETIC SCREENING; HETEROZYGOTE; HUMAN; HUNTINGTON CHOREA; MALE; MOTOR DYSFUNCTION; PRIORITY JOURNAL; REACTION TIME; SYMPTOMATOLOGY;

EID: 0030782259     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.1997.00550230030012     Document Type: Article

References (25)

1. Gusella JF, Wexler NS, Conneally PM, et al. A polymorphic DNA marker genetically linked to Huntington's disease. Nature. 1983;306:234-239.
2. Roos RAC, Vegter-van der Vlis M, Hermans J, et al. Age at onset in Huntington's disease: effect of line of inheritance and patient's sex. J Med Genet. 1991;28: 515-519.
3. Lyle OE, Gottesman II. Premorbid psychometric indicators of the gene for Huntington's disease. J Consult Clin Psychol. 1977;45:1011-1022.
4. Lyle OE, Gottesman II. Subtle cognitive deficits as 15- to 20-year precursors of Huntington's disease. Adv Neurol. 1979;23:227-238.
5. Cain ED, Shoulson I. Psychiatric syndromes in Huntington's disease. Am J Psychiatry. 1983;140:728-734. B
6. Folstein SE. Huntington's Disease: A Disorder of Families. Baltimore, Md: John Hopkins University Press; 1991.
7. Jason GW, Pajurkova EM, Suchowersky O, et al. Presymptomatic neuropsychological impairment in Huntington's disease. Arch Neurol. 1988;45:769-773.
8. Diamond R, White RF, Myers RH, et al. Evidence of presymptomatic cognitive decline in Huntington's disease. J Clin Exp Neuropsychol. 1992;14:961-975.
9. Strauss ME, Brandt J. Are there neuropsychologic manifestations of the gene for Huntington's disease in asymptomatic, at-risk individuals? Arch Neurol. 1990; 7:905-908.
10. Giordani B, Berent S, Boivin MJ, et al. Longitudinal neuropsychological and genetic linkage analysis of persons at risk for Huntington's disease. Arch Neurol. 1995;52:59-64.
11. Blackmore L, Simpson SA, Crawford JR. Cognitive performance in UK sample of presymptomatic people carrying the gene for Huntington's disease. J Med Genet. 1995;32:358-362.
12. Tibben A, Timman R, Bannink EC, Duivenvoorden HJ. Three-year follow-up after presymptomatic testing for Huntington's disease in tested individuals and partners. Health Psychol. 1997;16:20-35.
13. De Boo GM, Tibben A, Hermans J, Maat-Kievit A, Roos RAC. Clinical assessment of early motor symptoms in Huntington's disease. Mov Disord. In press.
14. Lundervold AJ, Reinvang I. Neuropsychological findings and depressive symptoms in patients with Huntington's disease. Scand J Psychol. 1991;32:275-283.
15. Bamford KA, Caine ED, Kido DK, Plassche WM, Shoulson I. Clinical-pathologic correlation in Huntington's disease: a neuropsychological and computed tomography study. Neurology. 1989;39:796-801.
16. Rothlind JD, Bylsma FW, Peyser C, et al. Cognitive and motor correlates of everyday functioning in early Huntington's disease. J Nerv Ment Dis. 1993;181:194-199.
17. Podoll K, Caspary P, Lange HW, Noth J. Language functions in Huntington's disease. Brain. 1988;111:1475-1503.
18. Stinissen J, Willems PJ, Coetsier P, et al. W.A.I.S. Dutch Adaptation Wechsler Adult Intelligence Scale. Lisse, the Netherlands: Swets & Zeitlinger; 1970.
19. Wechsler D. Wechsler Memory Scale-Revised. New York, NY: Psychological Corp; 1987.
20. Mulder JL, Dekker R, Dekker PH. Verbale Leer en Geheugen Test (Dutch Adaptation of the California Verbal Learning Test). Lisse, the Netherlands: Swets; 1996.
21. Benton AL. The Revised Visual Retention Test. Berne, Switzerland: Verlag Hans Huber; 1981.
22. Stroop JR. Studies of interference in serial verbal reactions. J Exp Psychol. 1935; 18:643-662.
23. Nelson HE. A modified card sorting test sensitive to frontal lobe defects. Cortex. 1976;12:313-324.
24. Brandt J. Cognitive impairments in Huntington's disease: insights into the neuropsychology of the striatum. In: Boller F, and Grafman J, eds. Handbook of Neuropsychology. Amsterdam, the Netherlands: Elsevier Science Publishers; 1991;241-264.
25. Rosenberg NK, Sorensen SA, Christensen A. Neuropsychological characteristics of Huntington's disease carriers: a double blind study. J Med Genet. 1995; 32:600-604.