Suppression of bleomycin-induced increased production of nitric oxide and NF-kB activation by treatment with taurine and niacin

Advances in Experimental Medicine and Biology

Volumn 483, Issue , 2000, Pages 545-561

  Giri, S N ^a   Gurujeyalakshmi, G ^a   Wang, Y ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BLEOMYCIN; DNA BINDING PROTEIN; HYDROXYPROLINE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; NICOTINIC ACID; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, MOUSE; OXIDIZING AGENT; TAURINE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; DRUG EFFECT; GENETICS; IMMUNOLOGY; LUNG; MALE; METABOLISM; MOUSE;

ANIMALS; ANTIOXIDANTS; BLEOMYCIN; DNA-BINDING PROTEINS; HYDROXYPROLINE; I-KAPPA B PROTEINS; INTERLEUKIN-1; LUNG; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; NIACIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDANTS; TAURINE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034585405     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (32)

1. Crouch, E., 1990 Pathobiology of pulmonary fibrosis. Am J Physiol 259: 159-184.
2. Clark, J.G., Overton, J.E., Marino, B.A., Uitto, J. and Starcher, B.C., 1980 Collagen synthesis in bleomycin-induced pulmonary fibrosis in hamsters. J Lab Clin Med 96: 943-953.
3. Caspary W.J., Lanzo, D.A., and Niriak, C., 1982, Effect of deoxyribonucleic acid on the production of reduced oxygen by bleomycin and iron. Biochemistry 21: 334-338.
4. Sugiura, Y. and Kikuchi, T., 1978, Formation of superoxide and hydroxy radicals in iron (II)-bleomycin-oxygen system: Electron spin resonance detection by spin tapping. J Antibiot 31: 1310-1312.
5. Phan, S.H. and Kunkel, S.L., 1992, Lung cytokine production in bleomycin-induced pulmonary fibrosis. Exp Lung Res 18: 29-43.
6. Piguet, P.F., Collart, M.A., Grau, G.E., Kapanchi, Y. and Vassali, P., 1989, Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J Exp Med 170: 655-663.
7. Scheule, R.K., Perkins, R.C., Hamilton, R. and Holian, A., 1992, Bleomycin stimulation of cytokine secretion by the human alveolar macrophages. Am J Physiol 262: 386-L391.
8. Smith, R.E., Strieter, R.M., Phan, S.H. and Kunkel, S.L., 1996, C-C Chemokines: Novel mediators of the profibrotic inflammatory response to bleomycin challenge. Am J Respir Cell Mol Biol 15: 693-702.
9. Kobsik, L., Bredt, D.S., Lowenstein, C.J., Drazen, J., Gaston, B., Sugarbaker, D. and Stamler, J., 1993, Nitric oxide synthase in human and rat lung: Immunocytochemical and histochemical localization. Am J Respir Cell Mol Biol 9: 371-377.
10. Sessa, W.C., Harrison, Luthin, D.R., Pollock, J.S., Lynch, K.R., 1993, Genomic analysis and expression patterns reveal distinct genes for endothelial and brain nitric oxide synthase. Hypertension 21: 934-938.
11. Sherman, M., Aberhard, E.E., Wong, V.Z., Griscavge, J.M., and Ignarro, L.J., 1993, Pyrrolidine dithiocarbonate inhibits induction of rat nitric oxide synthase in rat alveolar macrophages. Biochem Biophys Res Commun 191: 1301-1308.
12. Huot, A.E. and Hacker, M.P., 1990, Role of reactive nitrogen intermediate production in alveolar macrophage-mediated cytostatic activity induced by bleomycin lung damage in rats. Cancer Res 50: 7863-7866.
13. Blackwell, T.S. and Christman, W.W., 1997, The role of nuclear factor-kB in cytokine gene regulation. Am J Respir Cell Mol Biol 17: 3-9.
14. Bauerle, P.A. and Henkel, T., 1994, Function and activation of NF-kappa B in the immune system. Ann rev Immunol 12: 141-179.
15. Schreck, R., Reiber, P. and Baeuerle, P.A., 1992, Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kB transcription factor and HIV-1. EMBO J 10: 2247-2258.
16. Wang, Q., Giri, S.N., Hyde, D.M. and Li, C., 1991, Amelioration of bleomycin-induced pulmonary fibrosis in hamsters by combined treatment with taurine and niacin. Biochem Pharmacol 42: 1115-1122.
17. Gurujeyalakshmi, G., Iyer, S.N., Hollinger, M.A. and Giri, S.N., 1996, Procollagen gene expression is down-regulated by taurine and niacin at the transcriptional level in the bleomycin hamster model of lung fibrosis. J Pharmacol Exp Therap 227: 1152-1157.
18. Giri, S.N., Hollinger, M.A. and Schiedt, M.J., 1981, The effects of paraquat and superoxide dismutase on pulmonary vascular permeatiblity and edema in mice. Arch Evin Health 36: 149-154.
19. Woessner, Jr., J.F., 1961, The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Anal Biochem 93: 440-444.
20. Ding, A.H., Nathan, C.F. and Stuehr, D.J., 1988, Release of reactive nitrogen intermediates from mouse peritoneal macrophages. J Immunol 141: 2407-2412.
21. 1 mRNA expression by taurine and niacin in the bleomycin hamster model of lung fibrosis. Am J Respir Cell Mol 18: 334-342.
22. Choi, A.M.K., Sylvester, S., Otterbein, L and Holbrook, N.J., 1995 Molecular responses to hyperoxia in vivo: Relationship to increased tolerance in aged rats. Am J Respir Cell Mol Biol 13: 74-82.
23. Gurujeyalakshmi, G., Hollinger, M.A. and Giri, S.N., 1999, Pirfenidone inhibits PDGF isoforms in the bleomycin hamster model of lung fibrosis at the translational level. Am J Physiol 216 (Lung Cell Mol Physiol 20): L311-L318.
24. Paredi, P., Kharitonov, S.A., Loukides, S., Pantelidis, P., DuBois, R.M. and Barnes, P.J., 1999, Exhaled nitric oxide is increased in active fibrosing alveolitis. Chest 115: 1352-1356.
25. Schuller-Levis, G., Quinn, M.R., Wright, C. and Park, E., 1994, Taurine protects against oxidant-induced lung injury: Possible mechanism(s) of action. Adv Exp Med Biol 359: 31-39.
26. Schuller-Levis, G., Gordon, R.E., Park, E., Pendino, K.J. and Laskin, D.L., 1994, Taurine protects rat bronchioles from acute ozone-induced lung inflammation and hyperplasia. Exp Lung Res 21: 877-888.
27. Wang, Q., Giri, S.N., Hyde, D.M. and Nakashima J.M., 1989, Effect of taurine on bleomycin-induced lung fibrosis in hamsters. Proc Soc Exp Biol Med 190: 330-338.
28. Wang, Q., Giri, S.N., Hyde, D.M., Nakamshima, J.M. and Javadi, I., 1990, Niacin attenuates bleomycin-induced lung fibrosis in the hamster. J Biochem Toxicol 5: 13-2239.
29. Brown, O.R., Heitkamp, M. and Song, C.S., 1981, Niacin reduces paraquat toxicity in rats. Science 212: 1510-1512.
30. Leff, J.A., Wilke, C.P., Hypertson, B.M., Shanley, P.F., Beehler, C.J. and Repine, J.E., 1993, Postinsult treatment with N-acetylcysteine decreases IL-1 induced neutrophil influx and lung leak in rats. Am J Physiol 265: L501-L506.
31. Nathens, A.B., Bitar, R., Davreux, C., Mujard, M., Marshall, J.C., Dackiw, A.P.B., Watson, R.W.G. and Rotstein, O.D., 1997, Pyrrolidine dithiocarbamate attenuates endotoxin-induced acute lung injury. Am J Respir Cell Mol Biol 17: 608-616.
32. Lin, Y.L. and Lin J.K., 1997, (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kB. Mol Pharmacol 52: 465-472.