Synthesis of optically active TAN-67, a highly selective delta opioid receptor agonist, and investigation of its pharmacological properties

Drug Design and Discovery

Volumn 17, Issue 4, 2000, Pages 325-330

  Fujii, H ^a   Kawai, K ^a   Kawamura, K ^a   Mizusuna, A ^a   Onoda, Y ^a   Murachi, M ^a   Tanaka, T ^a   Endoh, T ^a   Nagase, H ^a  

^a TORAY INDUSTRIES INC   (Japan)

Author keywords

agonist; (+)TAN 67; ( )TAN 67; Analgesics; Hyperalgesia; Opioid; Optical resolution

Indexed keywords

1,2,3,4,4A,5,12,12AALPHA OCTAHYDRO 4AALPHA (3 HYDROXYPHENYL) 2 METHYLQUINOLINO[2,3 G]ISOQUINOLINE; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; ISOQUINOLINE DERIVATIVE; TARTARIC ACID DERIVATIVE;

AGONIST; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BIOASSAY; CONTROLLED STUDY; CRYSTALLIZATION; DRUG POTENCY; DRUG PURITY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; EXPERIMENTAL TEST; HYPERALGESIA; IC 50; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OPTICAL RESOLUTION; PHYSICAL CHEMISTRY; RACEMIC MIXTURE; VAS DEFERENS;

ANALGESICS; ANIMALS; MALE; MICE; QUINOLINES; RECEPTORS, OPIOID, DELTA; VAS DEFERENS;

EID: 0034551754     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

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