The novel immunosuppressant FTY720 induces peripheral lymphodepletion of both T- and B-cells in cynomolgus monkeys when given alone, with Cyclosporine Neoral® or with RAD

Transplant Immunology

Volumn 8, Issue 3, 2000, Pages 177-187

  Quesniaux, Valerie F J ^a,b   Menninger, Klaus ^a   Kunkler, Adrien ^a   Vedrine, Corinne ^a   Bernhard, Mario ^a   Hedinger, Rene ^a   Kraus, Gerolf ^a   Schuurman, Henk Jan ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b CDTA   (France)

Author keywords

Cyclosporine Neoral ; Cynomolgus monkeys; FTY720; RAD

Indexed keywords

CYCLOSPORIN A; EVEROLIMUS; FINGOLIMOD;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BLOOD PRESSURE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG TOLERABILITY; HEART RATE; HEMATOLOGICAL PARAMETERS; IMMUNOPHENOTYPING; KIDNEY FUNCTION; LEUKOCYTE DIFFERENTIAL COUNT; LIVER FUNCTION; LYMPHOCYTE DEPLETION; MALE; MONKEY; MONKEY DISEASE; NONHUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE; TRANSPLANTATION;

ADMINISTRATION, ORAL; ANIMALS; B-LYMPHOCYTES; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; MACACA FASCICULARIS; PROPYLENE GLYCOLS; SIROLIMUS; SPHINGOSINE; T-LYMPHOCYTES; TRANSPLANTATION IMMUNOLOGY;

EID: 0034532250     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0966-3274(00)00025-3     Document Type: Article

References (24)

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