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Volumn 115, Issue 6, 2000, Pages 1059-1064

Elimination of CD4+ T cells enhances anti-tumor effect of locally secreted interleukin-12 on B16 mouse melanoma and induces vitiligo-like coat color alteration

Author keywords

CD8 positive T lymphocyte; Cytokine; Gene therapy; Th1; Th2

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 12;

EID: 0034526326     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.00156.x     Document Type: Article
Times cited : (62)

References (48)
  • 3
    • 0023682494 scopus 로고
    • Cyclophosphamide (Cy) -facilitated adoptive immunotherapy of a Cy-resistant tumour. Evidence that Cy permits the expression of adoptive T-cell mediated immunity by removing supressor T cells rather than by reducing tumour burden
    • (1988) Immunology , vol.65 , pp. 87-92
    • Awwad, M.1    North, R.J.2
  • 4
    • 0024255820 scopus 로고
    • Immunologically mediated regression of a murine lymphcma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity
    • (1988) J Exp Med , vol.168 , pp. 2193-2206
    • Awwad, M.1    North, R.J.2
  • 5
    • 0025246123 scopus 로고
    • Radiosensitive barrier to T-cell-mediated adoptive immunotherapy of established tumors
    • (1990) Cancer Res , vol.50 , pp. 2228-2233
    • Awwad, M.1    North, R.J.2
  • 10
    • 0023269443 scopus 로고
    • Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH 1 clones
    • (1987) J Immunol , vol.138 , pp. 3688-3694
    • Cher, D.J.1    Mosmann, T.R.2
  • 12
    • 0023916449 scopus 로고
    • Adoptive immunotherapy of syngeneic murine leukemia is enhanced by the combination of recombinant IFN-gamma and a tumor-specific cytotoxic T cell clone
    • (1988) J Immunol , vol.140 , pp. 2853-2857
    • De Graaf, P.W.1    Horak, E.2    Bookman, M.A.3
  • 14
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF) -producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
    • (1999) J Exp Med , vol.190 , pp. 355-366
    • Van Elsas, A.1    Hurwitz, A.A.2    Allison, J.P.3
  • 20
  • 30
    • 0022972367 scopus 로고
    • Radiation-induced, immunologically-mediated regression of an established tumor as an example of successful therapeutic immunomanipulation. Preferential elimination of suppressor T cells allows sustained production of effector T cells
    • (1986) J Exp Med , vol.164 , pp. 1652-1666
    • North, R.J.1
  • 31
    • 0025179982 scopus 로고
    • Elimination of cycling CD4+ suppressor T cells with an antimitotic drug releases non-cycling CD8+ T cells to cause regression of an advanced lymphoma
    • (1990) Immunology , vol.71 , pp. 90-95
    • North, R.J.1    Awwad, M.2
  • 32
    • 0021248368 scopus 로고
    • Generation and decay of the immune response to a progressive fibrosarcoma. 1. Ly-1+2-supressor T cells down-regulate the generation of Ly-1-2+ effector T cells
    • (1984) J Exp Med , vol.159 , pp. 1295-1311
    • North, R.J.1    Burssuker, I.2
  • 33
    • 0021909490 scopus 로고
    • Ly-1+2-supressor T cells down-regulate the generation of Ly-1-2+ effector T cells during progressive growth of P 815 mastocytoma
    • (1985) Immunology , vol.54 , pp. 47-56
    • North, R.J.1    Dye, E.S.2
  • 37
    • 0029813303 scopus 로고    scopus 로고
    • Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery
    • (1996) J Virol , vol.70 , pp. 6119-6125
    • Petmer, T.M.1    Roberts, T.R.2    Haynes, J.R.3
  • 43
    • 0019989719 scopus 로고
    • Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV 40 early region promoter
    • (1982) J Mol Appl Genet , vol.1 , pp. 327-341
    • Southern, P.J.1    Berg, S.2
  • 46
    • 0028043326 scopus 로고
    • Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in generation of T-helper cells type 1 and cytotoxic lymphocytes
    • (1994) Blood , vol.84 , pp. 4008-4027
    • Trinchieri, G.1
  • 47
    • 0029913787 scopus 로고    scopus 로고
    • T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: Interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (IL) 4/IL-10-producing (Th2) negative regulatory CD4+ T cells
    • (1996) J Exp Med , vol.183 , pp. 1001-1012
    • Xu, H.1    Dilulio, N.A.2    Fairchild, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.