NMDA receptor mediated changes in IGF-II gene expression in the rat brain after injury and the possible role of nitric oxide

Neuropathology and Applied Neurobiology

Volumn 26, Issue 6, 2000, Pages 513-521

  Giannakopoulou, M ^a   Mansour, M ^a   Kazanis, E ^a   Bozas, E ^a   Philpipidis, H ^a   Stylianopoulou, F ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

Brain injury; c fos; IGF II (insulin like growth factor II); MK 801; NO synthase

Indexed keywords

DIZOCILPINE; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SOMATOMEDIN B;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; HEMISPHERE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NEUROPROTECTION; NONHUMAN; ONCOGENE C FOS; PENETRATING TRAUMA; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN INJURIES; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; GENE EXPRESSION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR II; MALE; NEURONS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; TIME FACTORS;

EID: 0034519573     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0305-1846.2000.00286.x     Document Type: Article

References (63)

1. Cell death and control of cell survival in the oligodendrocyte lineage
2. Histochemical localization of IGF-I and IGF-II mRNA in the rat between birth and adulthood
3. Insulin-like growth factor II is induced during wound repair following hypoxic-ischemic injury in the developing rat brain
4. Co-ordinated and cellular specific induction of the components of the IGF/IGFBP axis in the rat brain following hypoxic-ischemic injury
5. At least three neurotransmitter systems mediate a stress-induced increase in c-fos mRNA in different rat brain areas
6. Expression of insulin-like growth factor-1 (IGF-1) and IGF-binding protein 2 (IGF-BP2) in the hippocampus following cytotoxic lesion of the dentate gyrus
7. Differential effects of MK-801 on brain-derived neurotrophic factor mRNA levels in different regions of the rat brain
8. Marked age-dependent neuroprotection by brain-derived neurotrophic factor against neonatal hypoxic-ischemic brain injury
9. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction
10. Hypoxia-ischemia-induced apoptotic cell death correlates with IGF-I mRNA decrease in neonatal rat brain
11. Expression of nitric oxide synthase in the cerebral microvasculature after traumatic brain injury in the rat
12. The insulin-like growth factors
13. The role of the insulin-like growth factors in the central nervous system
14. Nitric oxide synthase: Role as a transmitter/mediator in the brain and endocrine system
15. Hypothalamic derangement in traumatized patients: Growth hormone (GH) and prolactin response to thyrotrophin-releasing hormone and GH-releasing hormone
16. The developing CNS. A scenario for the action of proinsulin, insulin and insulin-like growth factors
17. Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats
18. Induction of Fos in glia-like cells after focal brain injury but not during wallerian degeneration
19. MK-801, an antagonist of NMDA receptors, inhibits injury-induced c-fos protein accumulation in rat brain
20. Patterns of immediate early gene mRNA expression following rodent and human traumatic brain injury
21. Neurotrophins and their receptors in nerve injury and repair
22. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity
23. Mannose 6-phosphate potentiates insuline-like growth factor II effects in cultured human neuroblastoma cells
24. Nitric oxide signaling in the central nervous system
25. Insulin-like growth factor II increases the rate of sciatic nerve regeneration in rats
26. A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury
27. The effects of IGF-1 treatment after hypoxic-ischemic brain injury in adult rats
28. The effects of insulin-like growth factor (IGF) -1, IGF-2, and des-IGF-1 on neuronal loss after hypoxicischemic brain injury in adult rats: Evidence for a role for IGF binding proteins
29. Insulin-like growth factor II (IGF-II) in human brain: Regional distribution of IGF-II and of higher molecular mass forms
30. N-methyl-D-aspartate receptors mediate activation of the c-fos proto-oncogene in a model of brain injury
31. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma
32. Nitric oxide, the enigmatic neuronal messenger: Its role in synaptic plasticity
33. Inducible nitric oxide synthase gene expression in brain following cerebral ischemia
34. 125I]insulin receptor binding sites in the rat hippocampal formation
35. The effect of MK-801 on extracellular neuroactive amino acids in the hippocampus after closed head injury followed by hypoxia in rats
36. Aging-related changes in IGF-II and c-fos gene expression in the rat brain
37. Brain derived neurotrophic factor is increased in cerebrospinal fluid of children suffering from asphyxia
38. Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke
39. Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose
40. The nitric oxide hypothesis of brain aging
41. MK-801 protects the neonatal brain from hypoxia and ischemic damage
42. Nitric oxide synthases: Roles, tolls, and controls
43. Insulin-like growth factor II stimulates motor nerve regeneration
44. Characterization of insulin-like growth factor binding proteins produced in the rat central nervous system
45. Peripherally administered insulin-like growth factor-I preserves hindlimb reflex and spinal cord noradrenergic circuitry following a central nervous system lesion in rats
46. The role of insulin-like growth factors in the nervous system
47. Insulin-like growth factor-1 (IGF-1) improves both neurological motor and cognitive outcome following experimental brain injury
48. Increase of insulin-like growth factor (IGF)-1, IGF binding protein-2 and -4 mRNAs following cerebral contusion
49. Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats
50. Plasma insulin-like growth factor I and IGF binding protein 3 levels in patients with acute cerebral ischemic injury
51. Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury
52. Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice
53. Increase in insulin-like growth factor II receptor within ischemic neurons following focal cerebral infarction
54. Expression of the insulin-like growth factor II gene in the choroid plexus and the leptomeninges of the adult rat central nervous system
55. Administration of nerve growth factor, brain-derived neurotrophic factor and insulin-like growth factor-II protects phosphate-activated glutaminase in the ischemic and reperfused rat retinas
56. βadrenergic receptors mediate a stress-induced decrease in IGF-II mRNA in the rat cerebellum
57. Developmental expression of insulin-like growth factor II receptor immunoreactivity in the rat central nervous system
58. Inducible nitric oxide synthase expression after traumatic brain injury and neuroprotecion with aminoguanidine treatment in rats
59. Spatial and temporal changes in the insulin-like growth factor (IGF) axis indicate autocrine/paracrine actions of IGF-I within wounds of the rat brain
60. Distinct sites of insulin-like growth factor (IGF) -II expression and localization in lesioned rat brain: Possible roles of IGF binding proteins (IGFBPs) in the mediation IGF-II activity
61. The role of the insulin-like growth factor system in the developing brain
62. Upregulation of neuronal nitric oxide synthase and mRNA, and selective sparing of nitric oxide synthase-containing neurons after focal ischemia in rat