Triggering receptors involved in natural killer cell-mediated cytotoxicity against choriocarcinoma cell lines

Human Immunology

Volumn 61, Issue 11, 2000, Pages 1055-1058

  Sivori, Simona ^a   Parolini, Silvia ^b   Marcenaro, Emanuela ^a   Millo, Romano ^a   Bottino, Cristina ^c   Moretta, Alessandro ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

Natural cytotoxicity; Triggering receptors; Trophoblast

Indexed keywords

HLA ANTIGEN CLASS 1; HLA E ANTIGEN; HLA G ANTIGEN; INTERLEUKIN 2; LIGAND; PROTEIN P44; RECEPTOR; TRIGGERING RECEPTOR; UNCLASSIFIED DRUG;

ANTIGEN RECOGNITION; CANCER CELL CULTURE; CELL SURFACE; CHORIOCARCINOMA; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; PRIORITY JOURNAL; TROPHOBLAST;

ANTIBODIES, MONOCLONAL; CHORIOCARCINOMA; CYTOTOXICITY TESTS, IMMUNOLOGIC; CYTOTOXICITY, IMMUNOLOGIC; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; INTERLEUKIN-2; KILLER CELLS, NATURAL; RECEPTORS, IMMUNOLOGIC; TUMOR CELLS, CULTURED;

EID: 0034501884     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(00)00201-9     Document Type: Conference Paper

References (19)

1. Evidence for the expression of HLA-C class I mRNA and protein by human first trimester trophoblast
2. Immunology: Keeping mother at bay
3. On the nature and function of human uterine granular lymphocytes
4. Human trophoblast and JEG choriocarcinoma cells are sensitive to lysis by IL-2-stimulated decidual NK cells
5. Cytotoxic activity against trophoblast and choriocarcinoma cells of large granular lymphocytes from human early pregnancy decidua
6. The CD94/NKG2-A inhibitory receptor complex is involved in natural killer cell-mediated recognition of cells expressing HLA-G1
7. HLA-G recognition by human natural killer cells: Involvement of CD94 both as inhibitory and as activating receptor complex
8. CD94/ NKG2 is the predominant inhibitory receptor involved in recognition for HLA-G by decidual and peripheral blood NK cells
9. The α1 domain of HLA-G1 and HLA-G2 inhibits cytotoxicity induced by natural killer cells: Is HLA-G the public ligand for natural killer cell inhibitory receptors?
10. Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis
11. A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells
12. Inhibitory receptors sensing Hla-G1 molecules in pregnancy: Decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, a novel HLA-G1-specific receptor
13. Trophoblast cell line resistance to NK lysis mainly involves an HLA class I-independent mechanism
14. The "natural cytotoxicity receptors" which trigger the NK-mediated cytolysis: Elusive no more
15. NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells is involved in non-MHC restricted tumor cell lysis
16. NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily
17. The JAR cell line, continuous human multi hormone production and controls
18. Isolation of hormone producing clonal lines of human choriocarcinoma
19. Human trophoblast cell resistance to decidual NK lysis is due to lack of NK target structure