Saturated BLAST: An automated multiple intermediate sequence search used to detect distant homology

Bioinformatics

Volumn 16, Issue 12, 2000, Pages 1105-1110

  Li, Weizhong ^a   Pio, Frederic ^b   Pawłowski, Krzysztof ^c   Godzik, Adam ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SIMON FRASER UNIVERSITY   (Canada)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; PROTEIN;

ALGORITHM; AMINO ACID SEQUENCE; ARTICLE; AUTOMATION; COMPUTER GRAPHICS; COMPUTER INTERFACE; COMPUTER PROGRAM; COMPUTER SYSTEM; CONTROLLED STUDY; DATA ANALYSIS; DATA BASE; GENE; GENETIC PROCEDURES; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; TECHNIQUE; TIME;

EID: 0034491129     PISSN: 13674803     EISSN: 13674811     Source Type: Journal    
DOI: 10.1093/bioinformatics/16.12.1105     Document Type: Article

References (21)

1. Local alignment statistics
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4. Hidden Markov models
5. Maximum discrimination hidden Markov models of sequence consensus
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7. Profile analysis: Detection of distantly related proteins
8. Superior performance in protein homology detection with the blocks database servers
9. Multiple sequence alignment with Clustal X
10. Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes
11. Hidden Markov models for detecting remote protein homologies
12. Hidden Markov models in computational biology. Applications to protein modeling
13. Predicting protein three-dimensional structure
14. SCOP: A structural classification of proteins database for the investigation of sequences and structures
15. Intermediate sequences increase the detection of homology between sequences
16. Sequence comparisons using multiple sequences detect three times as many remote homologues as pairwise methods
17. Improved tools for biological sequence comparison
18. Comparison of sequence profiles. Strategies for structural predictions using sequence information
19. Combining sensitive database searches with multiple intermediates to detect distant homologues
20. Protein structure alignment by incremental combinatorial extension (CE) of the optimal path
21. Identification of common molecular subsequences