Glutathione deficiency potentiates manganese-induced increases in compounds associated with high-energy phosphate degradation in discrete brain areas of young and aged rats

Aging Clinical and Experimental Research

Volumn 12, Issue 6, 2000, Pages 470-477

  Desole, M S ^a   Serra, P A ^a   Esposito, G ^a   Delogu, M R ^a   Migheli, R ^a   Fresu, L ^a   Rocchitta, G ^a   Miele, M ^a,b  

^a UNIVERSITY OF SASSARI   (Italy)

^b BETHLEM ROYAL HOSPITAL   (United Kingdom)

Author keywords

Aged rats; Brain; Glutathione deficiency; Manganese; Purine catabolism

Indexed keywords

ASCORBIC ACID; BUTHIONINE SULFOXIMINE; GLUTATHIONE; HYPOXANTHINE; INOSINE; MANGANESE; URIC ACID; XANTHINE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN STEM; CONTROLLED STUDY; CORPUS STRIATUM; DEGRADATION; ENERGY CONSUMPTION; ENZYME INHIBITION; INTOXICATION; MALE; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; RAT;

AGING; ANIMALS; ANTIMETABOLITES; ASCORBIC ACID; BRAIN; BUTHIONINE SULFOXIMINE; DEHYDROASCORBIC ACID; DRUG SYNERGISM; ENERGY METABOLISM; GLUTATHIONE; HYPOXANTHINE; INOSINE; MALE; MANGANESE; PHOSPHATES; RATS; RATS, WISTAR; TISSUE DISTRIBUTION; URIC ACID; XANTHINE;

EID: 0034485338     PISSN: 03949532     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03339879     Document Type: Article

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