The neprilysin family in health and disease

Advances in Experimental Medicine and Biology

Volumn 477, Issue , 2000, Pages 229-240

  Turner, A J ^a   Brown, C D ^a   Carson, J A ^a   Barnes, K ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Converting enzyme; Endothelin; Neprilysin; Peptidase; Phosphoramidon

Indexed keywords

ENDOTHELIN CONVERTING ENZYME; MEMBRANE METALLOENDOPEPTIDASE;

BLOOD GROUP KELL SYSTEM; CAENORHABDITIS ELEGANS; CONFERENCE PAPER; DROSOPHILA; ENZYME ACTIVITY; HUMAN; LACTOCOCCUS LACTIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROCESSING; STREPTOCOCCUS PARASANGUINIS;

ACYLATION; ANIMALS; ASPARTIC ENDOPEPTIDASES; BACTERIAL PROTEINS; CAENORHABDITIS ELEGANS; CARDIOVASCULAR DISEASES; DROSOPHILA MELANOGASTER; ENDOTHELINS; HELMINTH PROTEINS; HUMANS; INFLAMMATION; INSECT PROTEINS; KELL BLOOD-GROUP SYSTEM; LACTOCOCCUS LACTIS; MAMMALS; METALLOENDOPEPTIDASES; MULTIGENE FAMILY; NEOPLASM PROTEINS; NEOPLASMS; NEPRILYSIN; NEUROPEPTIDES; ORGAN SPECIFICITY; PAIN; PORPHYROMONAS GINGIVALIS; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); CAENORHABDITIS ELEGANS; LACTOCOCCUS LACTIS; MAMMALIA; PEPO; STREPTOCOCCUS PARASANGUINIS;

EID: 0034471702     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (50)

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11. The N-terminal segment of endothelin-converting enzyme (ECE) contains a di-leucine motif that can redirect neprilysin to an inracellular compartment in Madin-Darby canine kidney (MDCK) cells
12. Amino acid sequence of rabbit kidney neutral endopeptidase-24.11 (enkephalinase) deduced from a complementary DNA
13. Endothelin-converting enzyme-2 is a membranebound, phosphoramidon-sensitive metalloprotease with acidic pH optimum
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15. Streptococcus parasanguis pepO encodes an endopeptidase with structure and activity similar to those of enzymes that modulate peptide receptor signaling in eukaryotic cells
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38. CD10 (CALLA)/neutral endopeptidase 24.11 modulates inflammatory peptide-induced changes in neutrophil morphology, migration and adhesion proteins and is itself regulated by neutrophil activation
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48. XCE, a new member of the endothelin-converting enzyme and neutral endopeptidase family, is preferentially expressed in the CNS
49. Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzymegene