Constitutive lysosomal targeting and degradation of bovine endothelin- converting enzyme-1a mediated by novel signals in its alternatively spliced cytoplasmic tail

Journal of Biological Chemistry

Volumn 274, Issue 3, 1999, Pages 1509-1518

  Emoto, Noriaki ^a   Nurhantari, Yudha ^a   Alimsardjono, Haryanto ^a   Xie, Jian ^b   Yamada, Takahisa ^b   Yanagisawa, Masashi ^b   Matsuo, Masafumi ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN; ENDOTHELIN CONVERTING ENZYME; ENDOTHELIN CONVERTING ENZYME INHIBITOR;

ANIMAL CELL; ARTICLE; CATTLE; CELL MEMBRANE PERMEABILITY; CELLULAR DISTRIBUTION; CONGESTIVE HEART FAILURE; ENZYME ACTIVITY; ENZYME LOCALIZATION; ESSENTIAL HYPERTENSION; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; RESTENOSIS; TARGET CELL;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; ASPARTIC ENDOPEPTIDASES; CATTLE; CHO CELLS; CRICETINAE; CYTOPLASM; DNA MUTATIONAL ANALYSIS; ENDOTHELIN-1; LYSOSOMES; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH; PROTEIN SORTING SIGNALS; TRANSFECTION;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0033556165     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.3.1509     Document Type: Article

References (39)

1. Yanagisawa, M., Kurihara, H., Kimura, S., Tomobe, Y., Kobayashi, M., Mitsui, Y., Yazaki, Y., Goto, K., and Masaki, T. (1988) Nature 332, 411-415
2. Inoue, A., Yanagisawa, M., Kimura, S., Kasuya, Y., Miyauchi, T., Goto, K., and Masaki, T. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 2863-2867
3. Arai, H., Hori, S., Aramori, I., Ohkubo, H., and Nakanishi, S. (1990) Nature 348, 730-732
4. Sakurai, T., Yanagisawa, M., Takuwa, Y., Miyazaki, H., Kimura, S., Goto, K., and Masaki, T. (1990) Nature 348, 732-735
5. Clozel, M., Breu, V., Burri, K., Cassai, J. M., Fischli, W., Gray, G. A., Hirth, G., Loffler, B. M., Muller, M., Neidhart, W., and Ramuz, H. (1993) Nature 365, 759-761
6. Kiowski, W., Sutsch, G., Hunziker, P., Muller, P., Kim, J., Oechslin, E., Schmitt, R., Jones, R., and Bertel, O. (1995) Lancet 346, 732-736
7. Sakai, S., Miyauchi, T., Kobayashi, M., Yamaguchi, I., Goto, K., and Sugishita, Y. (1996) Nature 384, 353-355
8. Minamino, T., Kurihara, H., Takahashi, M., Shimada, K., Maemura, K., Oda, H., Ishikawa, T., Uchiyama, T., Tanzawa, K., and Yazaki, Y. (1997) Circulation 95, 221-230
9. Krum, H., Viskoper, R. J., Lacourciere, Y., Budde, M., and Charlon, V. (1998) N. Engl. J. Med. 338, 784-790
10. Kurihara, Y., Kurihara, H., Suzuki, H., Kodama, T., Maemura, K., Nagai, R., Oda, H., Kuwaki, T., Cao, W. H., Kamada, N., Jishage, K., Ouchi, Y., Azuma, S., Toyoda, Y., Ishikawa, T., Kumada, M., and Yazaki, Y. (1994) Nature 368, 703-710
11. Baynash, A. G., Hosoda, K., Giaid, A., Richardson, J. A., Emoto, N., Hammer, R. E., and Yanagisawa, M. (1994) Cell 79, 1277-1285
12. Hosoda, K., Hammer, R. E., Richardson, J. A., Baynash, A. G., Cheung, J. C., Giaid, A., and Yanagisawa, M. (1994) Cell 79, 1267-1276
13. Clouthier, D. E., Hosoda, K., Richardson, J A., Williams, S. C., Yanagisawa, H., Kuwaki, T., Kumada, M., Hammer, R. E., and Yanagisawa, M. (1998) Development 125, 813-824
14. Xu, D., Emoto, N., Giaid, A., Slaughter, C., Raw, S., de Wit, D., and Yanagisawa, M. (1994) Cell 78, 473-485
15. Shimada, K., Takahashi, M., and Tanzawa, K. (1994) J. Biol. Chem. 269, 18275-18278
16. Emoto, N., and Yanagisawa, M. (1995) J. Biol. Chem. 270, 15262-15268
17. Takahashi, M., Fukuda, K., Shimada, K., Barnes, K., Turner, A. J., Ikeda, M., Koike, H., Yamamoto, Y., and Tanzawa, K. (1995) Biochem. J. 311, 657-665
18. Barnes, K., Shimada, K., Takahashi, M., Tanzawa, K., and Turner, A. J. (1996) J. Cell Sci. 109, 919-928
19. Yanagisawa, H., Yanagisawa, M., Kapur, R. P., Richardson, J. A., Williams, S. C., Clouthier, D. E., de Wit, D., Emoto, N., and Hammer, R. E. (1998) Development 125, 825-836
20. Gui, G., Xu, D., Emoto, N., and Yanagisawa, M. (1993) J. Cardiovasc. Pharmacol. 22, S53-S56
21. Schweizer, A., Valdenaire, O., Nelbock, P., Deuschle, U., Dumas Milne Edwards, J. B., Stumpf, J. G., and Loffler, B. M. (1997) Biochem. J. 328, 871-877
22. Harrison, V. J., Barnes, K., Turner, A. J., Wood, E., Corder, R., and Vane, J. R. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 6344-6348
23. Barnes, K., Brown, C., and Turner, A. J. (1998) Hypertension 31, 3-9
24. Shimada, K., Takahashi, M., Ikeda, M., and Tanzawa, K. (1995) FEBS Lett. 371, 140-144
25. Barnes, K., Walkden, B. J., Wilkinson, T. C., and Turner, A. J. (1997) J. Neurochem. 68, 570-577
26. Matsumura, Y., Hisaki, K., Takaoka, M., and Morimoto, S. (1990) Eur. J. Pharmacol. 185, 103-106
27. Ikegawa, R., Matsumura, Y., Tsukahara, Y., Takaoka, M., and Morimoto, S. (1990) Biochem. Biophys. Res. Commun. 171, 669-675
28. Schmidt, M., Kroger, B., Jacob, E., Seulberger, H., Subkowski, T., Otter, R., Meyer, T., Schmalzing, G., and Hillen, H. (1994) FEBS Lett. 356, 238-243
29. Valdenaire, O., Rohrbacher, E., and Mattei, M. G. (1995) J. Biol. Chem. 270, 29794-29798
30. Luoh, S. M., Di Marco, F., Levin, N., Armanini, M., Xie, M. H., Nelson, C., Bennett, G. L., Williams, M., Spencer, S. A., Gurney, A., and de Sauvage, F. J. (1997) J. Mol. Endocrinol. 18, 77-85
31. Casteels, K. M., Mathieu, C., Waer, M., Valckx, D., Overbergh, L., Laureys, J. M., and Bouillon, R. (1998) Endocrinology 139, 95-102
32. Sakamoto, A., Yanagisawa, M., Sawamura, T., Enoki, T., Ohtani, T., Sakurai, T., Nakao, K., Toyo-oka, T., and Masaki, T. (1993) J. Biol. Chem. 268, 8547-8553
33. Hemsen, A., Ahlborg, G., Ottosson-Seeberger, A., and Lundberg, J. M. (1995) Regul. Pept. 55, 287-297
34. Suzuki, N., Matsumoto, H., Kitada, C., Kimura, S., Miyauchi, T., and Fujino, M. (1990) J. Immunol. Methods 127, 165-170
35. Pelham, H. R., and Munro, S. (1993) Cell 75, 603-605
36. Green, S. A., Setiadi, H., McEver, R. P., and Kelly, R. B. (1994) J. Cell Biol. 124, 435-448
37. Blagoveshchenskaya, A. D., Norcott, J. P., and Cutler, D. F. (1998) J. Biol. Chem. 273, 2729-2737
38. Setiadi, H., Disdier, M., Green, S. A., Canfield, W. M., and McEver, R. P. (1995) J. Biol. Chem. 270, 26818-26826
39. Turner, A. J., and Tanzawa, K. (1997) FASEB J. 11, 355-364