Mutagenesis of Glu403 to Cys in rabbit neutral endopeptidase-24.11 (neprilysin) creates a disulphide-linked homodimer: Analogy with endothelin-converting enzyme

Biochemical Journal

Volumn 327, Issue 3, 1997, Pages 925-929

  Hoang, Mien V ^a   Sansom, Clare E ^a   Turner, Anthony J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 CARBOXYPROPANOYL ALANYL ALANYL LEUCINE 4 NITROANILIDE; 3-CARBOXYPROPANOYL-ALANYL-ALANYL-LEUCINE-4-NITROANILIDE; ASPARTIC PROTEINASE; CYSTINE; DISULFIDE; ENDOTHELIN CONVERTING ENZYME; ENDOTHELIN-CONVERTING ENZYME 1; ENKEPHALIN[2 ALANINE 5 LEUCINE]; GLUTAMIC ACID; GLYCOPEPTIDE; MEMBRANE METALLOENDOPEPTIDASE; METALLOPROTEINASE; OLIGOPEPTIDE; PHOSPHORAMIDON; PROTEINASE INHIBITOR; THIORPHAN; COMPLEMENTARY DNA; CYSTEINE; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE];

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; ARTICLE; BIOSYNTHESIS; CELL STRAIN COS1; CHEMISTRY; COMPARATIVE STUDY; DIMERIZATION; GENETICS; HUMAN; IMMUNOBLOTTING; KINETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; RABBIT; RAT; SITE DIRECTED MUTAGENESIS; ANIMAL CELL; CELL MEMBRANE; CONTROLLED STUDY; DISULFIDE BOND; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; GENETIC TRANSFECTION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ASPARTIC ENDOPEPTIDASES; COS CELLS; CYSTINE; DIMERIZATION; DISULFIDES; ENKEPHALIN, LEUCINE-2-ALANINE; GLUTAMIC ACID; GLYCOPEPTIDES; HUMANS; IMMUNOBLOTTING; KINETICS; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEPRILYSIN; OLIGOPEPTIDES; PROTEASE INHIBITORS; PROTEIN CONFORMATION; RABBITS; RATS; THIORPHAN;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0030713349     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3270925     Document Type: Article

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