In vitro and in vivo efficacy of acid-sensitive transferrin and albumin doxorubicin conjugates in a human xenograft panel and in the MDA-MB-435 mamma carcinoma model

Journal of Drug Targeting

Volumn 8, Issue 5, 2000, Pages 305-318

  Kratz, F ^a   Roth, T ^a   Fichiner, I ^a   Schumacher, P ^a   Fiebig, H H ^a   Unger, C ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Doxorubicin; Drug protein conjugates; Human serum albumin; Human serum transferrin; In vitro and in vivo activity

Indexed keywords

ACID; ALBUMIN DOXORUBICIN; ANTINEOPLASTIC AGENT; CHLORAMBUCIL; DAUNORUBICIN; DOXORUBICIN; DOXORUBICIN DERIVATIVE; HYDRAZONE DERIVATIVE; METHOTREXATE; TRANSFERRIN DOXORUBICIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER MODEL; CHEMICAL BOND; CLONOGENIC ASSAY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CONJUGATION; DRUG EFFICACY; DRUG SCREENING; DRUG SENSITIVITY; DRUG STABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LETHALITY; MORTALITY; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; TOXICITY; TUMOR XENOGRAFT; WEIGHT REDUCTION;

EID: 0034470325     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611860008997908     Document Type: Article

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