p53 protein accumulation and p53 gene mutation in colorectal cancer

Pathology and Oncology Research

Volumn 6, Issue 4, 2000, Pages 275-279

  Nasierowska Guttmejer, Anna ^a   Trzeciak, Lech ^b   Nowacki, Marek P ^a   Ostrowski, Jerzy ^a,b  

^a INSTITUTE OF ONCOLOGY   (Poland)

^b MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

Author keywords

Colorectal cancer; Immunohistochemical studies; Molecular biology; p53 gene; p53 protein

Indexed keywords

BIOTIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY DO7; PROTEIN P53; STREPTAVIDIN; UNCLASSIFIED DRUG;

APPARATUS; ARTICLE; CANCER CLASSIFICATION; CANCER GRADING; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; FLUORESCENCE; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR GENETICS; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; TUMOR LOCALIZATION;

EID: 0034470209     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03187331     Document Type: Article

References (29)

1. The p53 network
2. An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
3. Association of p53 gene and protein alterations with metastases in colorectal cancer
4. TP53 and long-term prognosis in colorectal cancer: Mutation in the L3 zinc-binding domain predict poor survival
5. The clinical significance of p53 aberrations in human tumors
6. Comparative survival analysis of p53 gene mutation and protein accumulation in colorectal cancer
7. A study of stabilization of p53 protein versus point mutation in colorectal carcinoma
8. Comparison of p53 gene mutation and protein overexpression in colorectal cancer
9. Definition of a consensus binding site for p53
10. p53 point mutation and survival in colorectal cancer patients
11. Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
12. p53 in tumor pathology: Can we trust immunohistochemistry?-revisited!
13. Association of p53 mutations with short survival in colorectal cancer
14. p53 gene mutations in early colorectal carcinoma, de novo vs adenoma-carcinoma sequence
15. p53 mutations in human cancers
16. A new classification of rectal cancer
17. Immunohistochemical study of p53 expression in microwave-fixed, parrafin-embedded sections of colorectal carcinoma and adenoma
18. p53, the cellular gatekeeper for growth and division
19. Tumor suppressor genes and the practice of surgical pathology
20. Protein p53 accumulation and proliferative activity in adenomas and early carcinoma of the colorectum
21. Posttranslational regulation of the 54K cellular tumor antigen in normal and transformed cells
22. The p53 pathway
23. Clinical and pathological associations with p53 tumor-suppressor gene mutations and expression of p21WAFI/Cip1 in colorectal carcinoma
24. Prognostic significance of p53 overexpression and mutation in colorectal adenocarcinomas
25. Accumulation of p53 in relation to long-term prognosis in colorectal carcinoma
26. Significance of serum p53 antibody detection on chemosensitivity assay in human colorectal cancer
27. p53 protein in colorectal cancer: Clinicopathological correlation and prognosis significance
28. p53 analysis in diagnostic pathology. Biologic implications and possible clinical applications