Accumulation of p53 in relation to long-term prognosis in colorectal carcinoma

European Journal of Gastroenterology and Hepatology

Volumn 9, Issue 2, 1997, Pages 183-186

  Starzynska, Teresa ^a   Bromley, Mike ^d   Marlicz, Krzysztof ^a   Roberts, Stephen A ^c   Ucinski, Michal ^b   Stern, Peter L ^d,e  

^a POMERANIAN MEDICAL UNIVERSITY   (Poland)

^b Department of Oncological Surgery ^*  (Poland)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d CHRISTIE HOSPITAL   (United Kingdom)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Colorectal cancer; p53 accumulation; Prognosis

Indexed keywords

PROTEIN P53; RABBIT ANTISERUM;

AGED; ARTICLE; CANCER RECURRENCE; CANCER SURVIVAL; COLORECTAL CANCER; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RETROSPECTIVE STUDY;

EID: 0031054531     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199702000-00014     Document Type: Article

References (27)

1. Cancer Statistics 1993. Ca Cancer J Clin 1993; 43:1.
2. Ahlgren JD, Macdonald JS: Gastrointestinal Oncology. Philadelphia: JB Lippincott; 1992.
3. Krook JE, Moertel CG, Gunderson LL, et al.: Effective adjuvant surgical therapy for high-risk rectal carcinoma. N Engl J Med 1991, 324:709-715.
4. Moerteel CG, Fleming TR, MacDonald JS, et al.: Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma. N Engl J Med 1990, 322:352-358.
5. Lane DP: Mutations of the p53 gene and accumulation of the p53 protein: common steps found in the majority of human cancers. In Accomplishments in Cancer Research. Edited by Foriner JG, Rhodes JE. Philadelphia: JB Lippincott; 1990:252-266.
6. Lane DP: The regulation of p53 function. Int J Cancer 1994, 57:623-627.
7. Lane DP: On the expression of the p53 protein in human cancer. Mol Biol Rep 1994, 19:23-29.
8. Bartek J, Bartkowa J, Vojtesek B, et al.: Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies. Oncogene 1991, 6:1699-1703.
9. Fonseca L, Yonemura Y, De Aretxabala X, et al.: p53 detection as a prognostic factor in early gastric cancer. Oncology 1994, 51:485-490.
10. Oiwa S, Maehara Y, Ohno S, et al.: Growth pattern and p53 overexpression in patients with early gastric cancer. Cancer 1995, 75:1454-1459.
11. Starzynska T, Markiewski M, Domagala W, et al.: The clinical significance of p53 accumulation in gastric carcinoma. Cancer 1996, 77:2005-2012.
12. Thor AD, Moore II DH, Edgerton SM, et al.: Accumulation of p53 tumor suppressor gene protein: an independent marker of prognosis in breast cancers. J Natl Cancer Inst 1992, 84:845-855.
13. Allred DC, Clark CM, Elledge R, et al.: Association of p53 protein expression with tumour cell proliferation rate and clinical outcome in node-negative breast cancer. J Natl Cancer Inst 1993, 85:200-206.
14. Remvicos Y, Tominaga O, Hammel P, et al.: Increased p53 protein content of colorectal tumours correlates with poor survival. Br J Cancer 1992, 66:758-764.
15. Zeng BZ-S, Sarkis AS, Zhang Z-F, et al.: p53 nuclear overexpression: an independent predictor of survival in lymph node-positive colorectal cancer patients. J Clin Oncol 1994, 12:2043-2050.
16. Bell SM, Scott N, Cross D, et al.: Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer. Gastroenterology 1993, 104:57-64.
17. Scott NP, Sagar P, Steward J, et al.: p53 in colorectal cancer: clinicopathological correlation and prognostic significance. Br J Cancer 1991, 63:317-319.
18. Sun X-F, Carstensen JM, Zhang H, et al.: Prognostic significance of cytoplasmic p53 oncoprotein in colorectal adenocarcinoma. Lancet 1992, 340:1369-1373.
19. Sun X-F, Carstensen JM, Stal O, et al.: Prognostic significance of p53 expression in relation to DNA ploidy in colorectal adenocarcinoma. Virchows Archiv A Pathol Anat 1993, 423:443-448.
20. Bosari S, Viale G, Bossi P, et al.: Cyoplasmatic accumulation of p53 protein: an independent prognostic indicator in colorectal adenocarcinomas. J Natl Cancer Inst 1994, 86:681-687.
21. Yamaguchi A., Kurosaka Y, Fushida S, et al.: Expression of p53 protein in colorectal cancer and its relationship to short-term prognosis. Cancer 1992, 70:2778-2784.
22. Yamaguchi A., Nakagawara G, Kurosaka Y, et al.: p53 immunoreaction in endoscopic specimens of colorectal cancer, and its prognostic significance. Br J Cancer 1993, 68:399-402.
23. Starzynska T, Bromley M, Ghosh A, et al.: Prognostic significance of p53 overexpression in gastric and colorectal carcinoma. Br J Cancer 1992, 66:558-562.
24. Dukes CE: The classification of cancer of the rectum. J Pathol Bacteriol 1932, 35:1489-1494.
25. Peto R, Pike MC, Armitage P, et al.: Design and analysis of randomised clinical trials requiring prolonged observation of each patient. I. Introduction and design. Br J Cancer 1976, 34:585-612.
26. Peto R, Pike MC, Armitage P, et al.: Design and analysis of randomised clinical trials requiring prolonged observation of each patient. II. Analysis and examples. Br J Cancer 1977, 35:1-39.
27. Fielding LP, Henson DE: Multiple prognostic factors and outcome analysis in patients with cancer. Cancer 1993, 71:2426-2429.