Comparative survival analysis of p53 gene mutations and protein accumulation in colorectal cancer

Oncology

Volumn 55, Issue 3, 1998, Pages 249-257

  Caldes, Trinidad ^b   Iniesta, Pilar ^a   Vega, Francisco J ^a   De Juan, Carmen ^a   Lopez, Jose A ^b   Diaz Rubio, Eduardo ^b   Fernandez, Cristina ^b   Cerdan, Javier ^b   Balibrea, Jose L ^b   Benito, Manuel ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b HOSPITAL CLÍNICO SAN CARLOS   (Spain)

Author keywords

Colorectal cancer; p53 mutations; p53 protein accumulation; Prognostic factors

Indexed keywords

MONOCLONAL ANTIBODY; PROTEIN P53;

ADULT; ARTICLE; CANCER SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; DNA SEQUENCE; EXON; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MISSENSE MUTATION; POINT MUTATION; PRIORITY JOURNAL; PROGNOSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROGNOSIS; SURVIVAL ANALYSIS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0031968966     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000011859     Document Type: Article

References (50)

1. Wiggers T, Arends JW, Schutte B, Volovics L, Bosman FT: A multivariate analysis of pathologic prognostic indicators in large bowel cancer. Cancer 1988;61:386-395.
2. Lane DP, Crawford LV: T antigen is found to a host protein in SV 40-transformed cells. Nature 1979;278:261-263.
3. Kern SE, Kinzler KW, Bruskin A, Jaroz D, Friedman P, Prives C, Vogelstein B: Identification of p53 as a sequence-specific DNA-binding protein. Science 1991;252:1708-1711.
4. Muleris M, Salmon RJ, Zafrani B, Girodet J, Dutrillaux B: Consistent deficiencies of chromosome 18 and the short arm of choromosome 17 in eleven cases of human large bowel cancer: A possible recessive determinism. Ann Genet 1985;28:206-213.
5. Vogelstein B, Fearon ER, Kern SE, Hamilton SR, Presinger AC, Nakamura Y, White R: Allelo type of colorectal carcinomas. Science 1989;244:207-211.
6. Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P: Mutations in the p53 gene occur in diverse human tumor types. Nature 1989;342:705-708.
7. Hollstein M, Sidransky D, Vogelstein B, Harris CC: p53 mutations in human cancers. Science 1989;244:207-211.
8. Top B, Mooi WJ, Klaver SG, Boerrignter L, Wisman P, Elbers HR, Visser S, Rodenhuis S: Comparative analysis of p53 gene mutations and protein accumulation in human non-small-cell lung cancer. Int J Cancer 1995;64:83-91.
9. Levine AJ, Momand J, Finlay CA: The p53 tumor suppressor gene. Nature 1991;351:453-456.
10. Bartek J, Bartkova J, Vojtesek B, Staskova Z, Lukas J, Rejthar A, Kovarik J, Midgley CA, Gannon JV, Lane DP: Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies. Oncogene 1991;6:1699-1703.
11. Porter PL, Gown AM, Kramp SG, Coltrera MD: Widespread p53 overexpression in human malignant tumors. Am J Pathol 1992;140: 145-153.
12. Kohler MF, Berdruck A, Davidoff AM, Humphrey PA, Dodge RK, Iglehart JD, Soper JT, Clarke-Pearson DL, Bast RC Jr, Marks JR: Overexpression and mutation of p53 in endometrial carcinoma. Cancer Res 1992;52:1622-1627.
13. Maestro R, Dolcetti R, Gasparoto D, Doglioni C, Pelucchi S, Barzan L, Grandi E, Boiocchi M: High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx. Oncogene 1992;7:1159-1166.
14. Marks JR, Davidoff AM, Kerns BJ, Humphrey PA, Pence JC, Dodge RK, Clarke-Pearson DL, Iglehart JD, Bast RC Jr, Berchuck A: Overexpression and mutation of p53 in epithelial ovarian cancer. Cancer Res 1991;51:2979-2984.
15. Thor AD, Moore DH II, Edgerton SM, Kawasaki ES, Reihsaus E, Lynch HT, Marcus JN, Schwartz L, Chen LC, Mayall BH: Accumulation of p53 tumor suppressor gene protein: An independent marker of prognosis in breast cancers. J Natl Cancer Inst 1992;84:845-855.
16. Silvestrini R, Benini E, Daidone MG, Veneroni S, Boracchi P, Cappelletti V, DiFronzo G, Veronesi U: p53 as an independent prognostic marker in lymph node negative breast cancer patients. J Natl Cancer Inst 1993;85:965-970.
17. Barton CM, Staddon SL, Hughes CM, Hall PA, O'Sullivan C, Kloppel G, Theis B, Russell RC, Neoptolemos J, Williamson RC: Abnormalities of the p53 tumor suppressor gene in human pancreatic cancer. Br J Cancer 1991;64:1076-1082.
18. Crook T, Wrede D, Tidy JA, Mason WP, Evan DJ, Vousdn KH: Clone p53 mutation in primary cervical cancer: Association with human papillomavirus negative tumors. Lancet 1992; 339:1070-1073.
19. Kohler MF, Kerns BJM, Humphrey PA, Marks JR, Bast RCJ, Berchuck A: Mutation and overexpression of p53 in early-stage epithelial ovarian cancer. Obstet Gynecol 1993;81:643-650.
20. Villuendas R, Piris MA, Algara P, Sánchez-Beato M, Sánchez-Verde L, Martinez JC, Orradre JL, Garcia P, López C, Martinez P: Expression of p53 protein in Non-Hodgkin's lymphomas is not always dependent on p53 gene mutations. Blood 1993;82:3151-3156.
21. Dix B, Robbins P, Carello S, House A, Iacopetta B: Comparison of p53 gene mutation and protein overexpression in colorectal carcinomas. Br J Cancer 1994;70:585-590.
22. Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howly PM: The E6 oncoprotein encoded by human papilloma virus types 16 and 18 promoted the degradation of p53. Cell 1990; 63:1129-1133.
23. Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B: Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 1992;358:80-85.
24. Orita M, Iwahana H, Kanazawa H, Hayashi K, Sekiya T: Detection of polymorphisms of human DNA by gel electrophoresis as single strand conformation polymorphisms. Proc Natl Acad Sci USA 1989;86:2766-2770.
25. Orita M, Suzuki Y, Sekiya T, Hayashi K: Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 1989;5:874-879.
26. Morson BC, Sobin LH: Histological typing of intestinal tumors. International histological classification of tumors. Geneva, WHO, 1976, vol 15.
27. Dukes CE: The classification of cancer of the rectum. J Pathol Bacteriol 1932;35:323-332.
28. Blin N, Stafford DW: A general method for isolation of high molecular weight DNA from eukaryotes. Nucleic Acids Res 1976;3:2303-2308.
29. Hsu SM, Raine L, Fanger H: The use of avidine-biotin-peroxidase complex (ABC) in immunoperoxidase technique: A comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981;29:577-580.
30. Sanger F, Nicklen S, Coulson AR: DNA sequencing with chain terminating inhibitors. Proc Natl Acad Sci USA 1977;74:5463-5467.
31. Kaplan EL, Meir P: Nonparametric estimation from incomplete observation. J Am Stat Assoc 1958;53:457-481.
32. Cox DR: Regression models and life tables. J R Stat Soc 1972;34:197-220.
33. Iniesta P, Caldes T, Vega FJ, López JA, Diaz-Rubio E, Cerdán J, Torres A, Balibrea JL, Benito M: Prevalence of p53 overexpression or mutations, but not K-ras mutations, in recurrent patients affected by colorectal carcinoma. Int J Oncol 1995;7:1319-1325.
34. Kikuchi-Yanoshita R, Konishi M, Ito S, Seki M, Tanaka K, Maeda Y, Iino H, Fukayama M, Koike M, Mori T: Genetic changes of both p53 alleles associated with the conversion from colorectal adenoma to early carcinoma in familial adenomatous polyposis and non-familial adenomatous polyposis patients. Cancer Res 1992;52:3965-3971.
35. Vanden Ber FM, Tiggers AJ Schipper MEI, Den Hartogjager FCA, Kroe WGM, Walbomers JMM: Expression of the nuclear oncogene p53 in colon tumors. J Pathol 1989;157:193-199.
36. Baas IO, Mulder JWR, Offerhaus GJA, Vogelstein B, Hamilton SR: An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms. J Pathol 1994;172:5-12.
37. Bourdon JC, D'Errico A, Paterlini P, Grigioni W, May E, Debuire E: p53 protein accumulation in European hepatocellular carcinoma is not always dependent on p53 gene mutation. Gastroenterology 1995;108:1176-1182.
38. Moll UM, Rion G, Levine AJ: Two distinct mechanisms alter p53 in breast cancer: Mutation and nuclear exclusion. Proc Natl Acad Sci USA 1992;89:7262-7268.
39. Caron de Fromentel C, Soussi T: TP53 tumor suppressor gene: A model for investigating human mutagenesis. Genes Chromosomes Cancer 1992;4:1-15.
40. Oliner JD, Pietenpol JA, Thiagalingam S, Gyuris J, Kinzler KW, Vogelstein B: Oncoprotein MDM2 conceals the activation domain of tumor suppressor p53. Nature 1993;362:857-860.
41. Momand J, Zambetti GP, Olson DC, George D, Levine AJ: The mdm2 oncogene product forms a complex with the protein and inhibits p53 mediated transactivation. Cell 1992;69: 1237-1245.
42. Horio Y, Takahashi T, Kuroishi T, Hibi K, Suyama M, Niimi T, Shimokata K, Yamakawa K, Makamura Y, Ueda R: Prognostic significance of p53 mutations and 3p deletions in primary resected non-small cell lung cancer. Cancer Res 1993;53:1-4.
43. Mazars R, Spinardi L, Bencheikh M, Simony-Lafontaine J, Jeanteur P, Theillet C: p53 mutations occur in aggressive breast cancer. Cancer Res 1992;52:3918-3923.
44. Marchetti A, Buttita F, Merlo G, Diella F, Pellegrini S, Pepe S, Macchiarini P, Chella A, Angeletti CA, Callahan R: p53 alterations in non-small-cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes. Cancer Res 1993;53:2846-2851.
45. Allred DC, Clark GH, Elledge R, Fuqura SAW, Brown RW, Chamnes GC, Osborne CK, Mc Guire WL: Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J Natl Cancer Inst 1993;85:200-206.
46. Remvikos Y, Tominaga O, Hammel P, Laurent-Puig P, Salmon RJ, Dutrillaux B, Thomas G: Increased p53 protein content of colorectal tumors correlates with poor survival. Br J Cancer 1992;66:758-764.
47. Starzynska T, Bromley M, Ghohsh A, Sterm PL: Prognostic significance of p53 overexpression in gastric and colorectal cancer. Br J Cancer 1992;66:558-562.
48. Bell SM, Scott N, Cross D, Sagar P, Lewis FA, Blair GE, Taylor GR, Dixon MF, Quirke P: Prognostic value of p53 overexpression and cKi-ras gene mutations in colorectal cancer. Gastroenterology 1993;104:57-64.
49. Scott NP, Sagar P, Stewart J, Blair GE, Dixon MF, Quieke P: p53 in colorectal cancer: Clinicopathological correlations and prognosis significance. Br J Cancer 1991;63:317-319.
50. Hamelin R, Laurent-Puig P, Oeschwang S, Jego N, Asselain B, Remvikos Y, Girodet J, Salmon RJ, Thomas G: Association of p53 mutations with short survival in colorectal cancer. Gastroenterology 1994;106:42-48.