Does the polymorphism of cytochrome P-450 2E1 affect the metabolism of N,N-dimethylformamide? Comparison of the half-lives of urinary N-methylformamide

Archives of Toxicology

Volumn 74, Issue 12, 2001, Pages 755-759

  Nomiyama, Tetsuo ^a   Nakashima, Hiroshi ^a   Sano, Yuri ^a   Chen, Li Ling ^a   Tanaka, Shigeru ^b   Miyauchi, Hiroyuki ^c   Yamauchi, Tsuneyuki ^d   Sakurai, Haruhiko ^a   Omae, Kazuyuki ^a  

^a KEIO UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY   (Japan)

^c Association of Industrial Health   (Japan)

^d JAPAN INDUSTRIAL SAFETY AND HEALTH ASSOCIATION   (Japan)

Author keywords

Cytochrome; Genetic polymorphism; Genotype; N,N Dimethylformamide; P450 2E1; Phenotype

Indexed keywords

CYTOCHROME P450; N,N DIMETHYLFORMAMIDE;

ARTICLE; DRUG EXPOSURE; DRUG HALF LIFE; GENETIC POLYMORPHISM; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMIDITY; JAPAN; OCCUPATIONAL EXPOSURE; PHENOTYPE; PRIORITY JOURNAL; URINALYSIS;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, INHALATION; ADULT; BIOTRANSFORMATION; CYTOCHROME P-450 CYP2E1; DIMETHYLFORMAMIDE; DNA; DNA PRIMERS; GENE FREQUENCY; HUMANS; MALE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 0034467648     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040000197     Document Type: Article

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