Genetic characterization of transactivation of the human T-cell leukemia virus type 1 promoter: Binding of tax to tax-responsive element 1 is mediated by the cyclic AMP-responsive members of the CREB/ATF family of transcription factors

Molecular and Cellular Biology

Volumn 16, Issue 5, 1996, Pages 2174-2182

  Bantignies, Frédéric ^a   Rousset, Raphaël ^a   Desbois, Christelle ^a   Jalinot, Pierre ^a  

^a UNIVERSITÉ DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; TAX PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN T CELL LEUKEMIA VIRUS 1; PRIORITY JOURNAL; PROMOTER REGION; SACCHAROMYCES CEREVISIAE; TRANSACTIVATION;

ACTIVATING TRANSCRIPTION FACTORS; AMINO ACID SEQUENCE; ANIMALS; BETA-GALACTOSIDASE; BLOOD PROTEINS; CLONING, MOLECULAR; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYTOCHROME C GROUP; CYTOCHROMES C; DNA, COMPLEMENTARY; FUNGAL PROTEINS; GENE PRODUCTS, TAX; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; LYMPHOCYTES; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RATS; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EUKARYOTA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN T-LYMPHOTROPIC VIRUS 1; SACCHAROMYCES CEREVISIAE;

EID: 0029880355     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.5.2174     Document Type: Article

References (61)

1. Adya, N., and C.-Z. Giam. 1995. Distinct regions in human T-cell lymphotropic virus type I Tax mediate interactions with activator protein CREB and basal transcription factors. J. Virol. 69:1834-1841.
2. Adya, N., L.-J. Zhao, W. Huang, I. Boros, and C.-Z. Giam. 1994. Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB. Proc. Natl. Acad. Sci USA 91:5642-5646
3. Alexandre, C., and B. Verrier. 1991. Four regulatory elements in the human c-fos promoter mediate transactivation by HTLV-I Tax protein Oncogene 6:543-551.
4. Anderson, M. G., and W. S. Dynan. 1994. Quantitative studies of the effect of HTLV-I Tax protein on CREB protein-DNA binding. Nucleic Acids Res 22:3194-3201
5. Ballard, D. W., E. Böhnlein, J. W. Lowenthal, Y. Wano, B. R. Franza, and W. C. Greene. 1988. HTLV-I Tax induces cellular proteins that activate the kB element in the IL-2 receptor a gene Science 241:1652-1655.
6. Béraud, C., G. Lombard-Platet, Y. Michal, and P. Jalinot. 1991 Binding of the HTLV-I Tax1 transactivator to the inducible 21 bp enhancer is mediated by the cellular factor HEB1. EMBO J 10:3795-3803.
7. Berkowitz, L. A., and M. Z. Gilman. 1990 Two distinct forms of active transcription factor CREB (cAMP response element binding protein). Proc. Natl Acad Sci. USA 87:5258-5262.
8. Boeke, J. D., F. LaCroute, and G. R. Fink. 1986 A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast; 5′-fluoro-orotic acid resistance Mol. Gen Genet 197:345-346
9. Brady, J., K.-T. Jeang, J. Duvall, and G. Khoury. 1987. Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeat. J. Virol. 61:2175-2181.
10. Brauweiler, A., P. Garl, A. A. Franklin, H. A. Giebler, and J. K. Nyborg. 1995. A molecular mechanism for human T-cell leukemia virus latency and Tax transactivation. J. Biol Chem. 270:12814-12822.
11. Breeden, L., and K. Nasmyth. 1985. Regulation of the yeast HO gene. Cold Spring Harbor Symp. Quant Biol. 50:643-650
12. Cao, Q. P., S. Pitt, J. Leszyk, and E. F. Baril. 1994. DNA-dependent ATPase from HeLa cells is related to human Ku autoantigen. Biochemistry 33:8548-8557
13. Caron, C., R. Rousset, C. Béraud, V. Moncollin, J.-M. Egly, and P. Jalinot. 1993 Functional and biochemical interaction of the HTLV-I Tax1 transactivator with TBP. EMBO J 12:4269-4278.
14. Chan, J. Y. C., M. I. Lerman, B. S. Prabhakar, O. Isozaki, P. Santisteban, R. C. Kuppers, E. L. Oates, A. L. Notkins, and L. D. Kohn. 1989 Cloning and characterization of a cDNA that encodes a 70-kDa novel human thyroid autoantigen. J. Biol. Chem. 264:3651-3654.
15. Chevray, P. M., and D. Nathans. 1992. Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of jun Proc. Natl Acad. Sci. USA 89:5789-5793.
16. Crenon, I., C. Béraud, P. Simard, J. Montagne, P. Veschambre, and P. Jalinot. 1993 The transcriptionally active factors mediating the effect of the HTLV-I Tax transactivator on the IL-2Ra kB enhancer include the product of the c-rel proto-oncogene. Oncogene 8:867-875.
17. de Groot, R. P., J. den Hertog, J. R. Vandenheede, J. Goris, and P. Sassone-Corsi. 1993. Multiple and cooperative phosphorylation events regulate the CREM activator function. EMBO J. 12:3903-3911.
18. Durfee, T., K. Becherer, P.-L. Chen, S.-H. Yeh, Y. Yang, A. E. Kilburn, W.-H. Lee, and S. J. Elledge. 1993. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit Genes Dev. 7:555-569.
19. Felber, B. K., H. Paskalis, C. Kleinman-Ewing, F. Wong-Staal, and G. N. Paslakis. 1985 The pX protein of HTLV-I is a transcriptional activator of its long terminal repeats. Science 229:675-679.
20. Foulkes, N. S., E. Borrelli, and P. Sassone-Corsi. 1991. CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription. Cell 64:739-749.
21. Franklin, A. A., M. F. Kubik, M. N. Uittenbogaard, A. Brauweiler, P. Utaisincharoen, M.-A. H. Matthews, W. S. Dynan, J. P. Hoëffler, and J. K. Nynorg. 1993. Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB). J. Biol. Chem. 268:21225-21231.
22. 1 protein of human T-cell leukemia virus type I. Proc. Natl. Acad. Sci. USA 85:8526-8530.
23. Fujii, M., H. Tsuchiya, T. Chuhjo, T. Akizawa, and M. Seiki. 1992. Interaction of HTLV-I Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes. Genes Dev 6:2066-2076.
24. Fujimoto, T., J.-I. Fujisawa, and M. Yoshida. 1994. Novel isoforms of human cyclic AMP-responsive element modulator (hCREM) mRNA. J. Biochem. 115:298-303
25. Fujisawa, J.-I., M. Seiki, T. Kiyokawa, and M. Yoshida. 1985. Functional activation of the long terminal repeat of human T-cell leukemia virus type I by a trans-acting factor. Proc. Natl. Acad. Sci. USA 82:2277-2281.
26. tax) of human T-cell leukemia virus type I that is distinct from cyclic AMP- and 12-O-tetradecanoylphorbol-13-acetate-responsive elements. J. Virol. 63:3234-3239.
27. Genersch, E., C. Eckerskorn, F. Lottspeich, C. Herzog, K. Kühn, and E. Pöschl. 1995. Purification of the sequence-specific transcription factor CTCBF, involved in the control of human collagen IV genes: subunits with homology to Ku antigen. EMBO J. 14:791-800.
28. Gietz, D., A. St. Jean, R. A. Woods, and R. H. Schiestl. 1992. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20:1425.
29. Gonzales, G. A., K. K. Yamamoto, W. H. Fischer, D. Karr, P. Menzel, W. Biggs III, W. W. Vale, and M. R. Montminy. 1989. A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence Nature (London) 337:749-752
30. Guarente, L. 1983. Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol. 101:181-191.
31. Guarente, L., and T. Mason. 1983. Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site. Cell 32:1279-1286.
32. Hai, T., F. Liu, W. J. Coukos, and M. R. Green. 1989 Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev. 3:2083-2090
33. Hoffman, C. S., and F. Winston. 1987. A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57:267-272.
34. Hummler, E., T. J. Cole, J. A. Blendy, R. Ganss, A. Aguzzi, W. Schmid, F. Beermann, and G. Schütz. 1994. Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors. Proc Natl. Acad. Sci. USA 91:5647-5651
35. x encoded by human T-cell leukemia virus type I. EMBO J. 5:2883-2888.
36. Jeang, K. T., S. G. Widen, O. J. Semmes, and S. H. Wilson. 1990. HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase gene. Science 247:1082-1084.
37. Laoide, B. M., N. S. Foulkes, F. Schlotter, and P. Sassone-Corsi. 1993. The functional versatility of CREM is determined by its modular structure. EMBO J. 12:1179-1191.
38. Leung, K., and G. J. Nabel. 1988. HTLV-I transactivator induces interleukin-2 receptor expression through an NF-κB like factor. Nature (London) 333:776-778.
39. Liu, F., and M. R. Green. 1990 A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein. Nature (London) 61:1217-1224
40. Marriott, S. J., P. F. Lindholm, K. M. Brown, S. D. Gitlin, J. F. Duvall, M. F. Radonovich, and J. N. Brady. 1990 A 36-kilodalton cellular transcription factor mediates an indirect interaction of human T-cell leukemia/lymphoma virus type I Tax1 with a responsive element in the viral long terminal repeat Mol. Cell. Biol. 10:4192-4201.
41. Masquilier, D., N. S. Foulkes, M.-G. Mattei, and P. Sassone-Corsi. 1993. Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript. Cell Growth Differ. 4:931-937
42. Messier, H., T. Fuller, S. Mangal, H. Brickner, S. Igarashi, J. Gaikwad, R. Fotedar, and A. Fotedar. 1993. p70 lupus autoantigen binds the enhancer of the T-cell receptor b-chain gene. Proc. Natl. Acad. Sci. USA 90:2685-2689.
43. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
44. Montagne, J., C. Beraud, I. Crenon, G. Lombard-Platet, L. Gazzolo, A. Sergeant, and P. Jalinot. 1990. Tax1 induction of the HTLV-I 21 bp enhancer requires cooperation between two cellular DNA-binding proteins. EMBO J. 9:957-964.
45. Paca-Uccaralertkun, S., L.-J. Zhao, N. Adya, J. V. Cross, B. R. Cullen, I. M. Boros, and C.-Z. Giam. 1994. In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax. Mol. Cell Biol 14:456-462.
46. Reeves, W. H., and Z. M. Sthoeger. 1989. Molecular cloning of cDNA encoding the p70 (Ku) lupus autoantigen. J. Biol. Chem. 264:5047-5052.
47. Roberts, M. R., Y. Han, A. Fienberg, L. Hunihan, and F. H. Ruddle. 1994. A DNA-binding activity, TRAC, specific for the TRA element of the transferrin receptor gene copurifies with the Ku autoantigen. Proc Natl. Acad. Sci USA 91:6354-6358.
48. Rosen, C. A., J. G. Sodroski, and W. A. Haseltine. 1985. Location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat. Cell 41:813-823.
49. Ruben, S., H. Poteat, T. H. Tan, K. Kawakami, R. Roeder, W. Haseltine, and C. A. Rosen. 1988. Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product. Science 241:89-91.
50. Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in S. cerevisiae. Genetics 122:19-27.
51. Smider, V., W. K. Rathmell, M. R. Lieber, and G. Chu. 1994. Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science 266:288-291.
52. Smith, M. R., and W. C. Greene. 1990. Identification of HTLV-I tax transactivator mutants exhibiting novel transcriptional phenotypes. Genes Dev. 4:1875-1885.
53. Suwa, A., M. Hirakata, Y. Takeda, S. A. Jesch, T. Mimori, and J. A. Hardin. 1994. DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA Proc Natl. Acad. Sci. USA 91:6904-6908.
54. Suzuki, T., J.-I. Fujisawa, M. Toita, and M. Yoshida. 1993. The trans-activator Tax of human T-cell leukemia virus type 1 (HTLV-I) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-I. Proc. Natl. Acad Sci. USA 90:610-614.
55. Suzuki, T., H. Hirai, J.-I. Fujisawa, T. Fujita, and M. Yoshida. 1993. A trans-activator Tax of human T-cell leukemia virus type 1 binds tu NF-kB p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF-kB site and CArG box. Oncogene 8:2391-2397.
56. Uittenbogaard, M. N., A. P. Armstrong, A. Chiaramello, and J. K. Nyborg. 1994. Human T-cell leukemia virus type I Tax protein represses gene expression through the basic helix-loop-helix family of transcription factors. J Biol. Chem. 269:22466-22469.
57. Wagner, S., and M. R. Green. 1993. HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization. Science 262:395-399.
58. Walker, W. H., B. M. Sanborn, and J. F. Habener. 1994. An isoform of transcription factor CREM expressed during spermatogenesis lacks the phosphorylation domain and represses cAMP-induced transcription Proc Natl. Acad. Sci. USA 91:12423-12427
59. Yin, M.-J., E. J. Paulssen, J.-S. Seeler, and R. B. Gaynor. 1995 Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type I Tax and CREB. J. Virol. 69:3420-3432
60. Yoshimura, T., J. Fujisawa, and M. Yoshida. 1990. Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-I: all contain a leucine zipper structure and basic ammo acid domain. EMBO J. 9:2537-2542.
61. Zhao, L.-J., and C.-Z. Giam. 1992. Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to the HTLV-I 21-base-pair repeats by protein-protein interaction Proc Natl. Acad. Sci. USA 89:7070-7074.