Oxygen, homeostasis, and metabolic regulation

Advances in Experimental Medicine and Biology

Volumn 475, Issue , 2000, Pages 311-335

  Hochachka, P W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE KINASE; CREATINE PHOSPHATE; OXYGEN;

CELL FUNCTION; CONCENTRATION RESPONSE; CONFERENCE PAPER; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; GASTROCNEMIUS MUSCLE; HEART MUSCLE OXYGEN CONSUMPTION; HOMEOSTASIS; HUMAN; HUMAN TISSUE; METABOLIC RATE; METABOLIC REGULATION; METABOLITE; OXYGEN CONSUMPTION; OXYGEN TISSUE LEVEL; PRIORITY JOURNAL; REACTION ANALYSIS; REACTION TIME; THERMODYNAMICS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CREATINE; CREATINE KINASE; HOMEOSTASIS; HUMANS; MUSCLES; OXYGEN; PHOSPHOCREATINE; RESEARCH DESIGN; SIGNAL TRANSDUCTION;

EID: 0034465719     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (79)

1. 31P magnetic resource spectroscopy of the soleus and gastrocnemius in sherpas during graded calf muscle exercise and recovery
2. Modelling the effects of hypoxia on ATP turnover in exercising muscle
3. Regulation of oxidative phosphorylation in the mammalian cell
4. The rationalization of high enzyme concentrations in metabolic pathways such as glycolysis
5. Where is the glycolytic complex? A cricial evaluation of the present data from muscle tissue
6. The force-velocity relationship of the ATP-dependent actin-myosin sliding causing cytoplasmic streaming in algal cells studied using a centrifuge microscope
7. Glycolysis is independent of oxygenation state in stimulated human skeletal muscle in vivo
8. Regulation of VO2max. Do current biochemical hypothesis fit in vivo data?
9. Role of glycolysis in adenylate depletion and repletion during work and recovery in teleost white muscle
10. Metabolic changes in skeletal muscle and blood in greyhounds during 800 m track sprint
11. Regulation of oxidative phosphorylation in the intact cell
12. O2 gradients from sarcolemma to cell interior in red muscle at maximal VO2
13. Myoglobin saturation in free-diving Weddell seals
14. Effect of acidosis on control of respiration in skeletal muscle
15. The residual dipolar coupling of the Cr/PCr methyl resonance in resting human medial gastrocnemius muscle
16. Animal plasma membrane energization by chemiosmotic H+ V ATPase control
17. Oxygen - A key regulatory metabolite in metabolic defense against hypoxia
18. Two research paths for probing the roles of oxygen in metabolic regulation
19. Regulation of ATP turnover over broad dynamic muscle work ranges
20. Cellular metabolic homeostasis during large scale change in ATP turnover rates in muscles
21. Does muscle creatine phosphokinase have access to the total pool of phosphocreatine + creatine
22. Limits and constraints in the scaling of oxidative and glycolytic enzymes in homeotherms
23. Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack
24. 31P Magnetic resonance spectroscopy of the sherpa heart: A PCr/ATP signature of metabolic defense against hypobaric hypoxia
25. Role of actomyosin ATPase in metabolic regulation during intense exercise
26. Integrating metabolic pathway fluxes with gene-to-enzyme expression rates
27. The role of O2 in regulating tissue respiration in dog muscle working in situ
28. Human muscle performance and PCr hydrolysis with varied inspired oxygen fractions: A 31P MRS study
29. Effect of gradual reduction in 02 delivery on intracellular homeostasis in contracting skeletal muscle
30. The pattern and mechanism of mitochondrial transport in axons
31. 02 Transport and its interaction with metabolism, a systems view of aerobic capacity
32. Molelcular motors: Structural adaptations to cellular functions
33. Creatine kinase knockout mice - What is the phenotype: Heart
34. Creatine kinase knockout mice - What is the phenotype: Skeletal muscle
35. 1H NMR studies of sarcoplasmic oxygenation in the red cell perfused rat heart
36. Diffusivity of myoglobin in intact
37. Determinants of the translational mobility of a small solute in cell cytoplasm
38. Control of glucose utilization in working perfused rat heart
39. The era of pathway quantification
40. Disassembly of actin filaments leads to increased rate and frequency of mitochondrial movements along microtubules
41. Effect of exercise on the creatine resonances in 1H MR spectra of human skeletal muscle
42. Regulation of oxygen consumption in fast- and slow-twitch muscle
43. Actin- and microtubule-dependent organelle motors: Interrelationships between the two motility systems
44. The role of Ca++ transport and matrix Ca in signal transduction in mammalian tissues
45. Unconventional myosins in cell movement, membrane traffic, and signal transduction
46. Myoglobin desaturation with exercise intensity in human gastrocnemius muscle
47. Evidence for an insulin substrate 1 independent insulin signaling pathway that mediates insulin responsive glucose transporter (GLUT4) translocation
48. Adenylate concentrations in Chara: Variability, effects of inhibitors, and relationship to protoplasmic streaming
49. Myoglobin 02 desaturation during exercise. Evidence of limited 02 transport
50. Changes in the contents of adenine nucleotides and intermediates of glycolysis and the citric acid cycle in flight muscle of the locust upon flight and the relationship to the control of the cycle
51. The regulation of ammonia uptake in Chara australis
52. Dynamics, structure, and function are coupled in the mitochondrial matrix
53. Actin-based organelle movement
54. Honeybee flight muscle phosphoglucoseisomerase: Matching enzyme capacities to flux requirements at a near-equilibrium reaction
55. Energy metabolism, enzymatic flux capacities, and metabolic flux rates in flying honeybees
56. Relationships between enzymatic flux capacities and metabolic flux rates: Nonequilibrium reactions in muscle glycolysis
57. Hummingbird flight: Sustaining the highest mass-specific metabolic rates among vertebrates
58. Photoregulation of cytoplasmic streaming: Cell biological dissection of signal transduction pathway
59. Design of the oxygen and substrate pathways. I. Model and strategy to test symmorphosis in a network structure
60. A control analysis exploration of the role of ATP utilization in glycolytic-flux control and glycolytic-metabolite concentration regulation
61. Comparative analysis of NMR and NIRS measurements of intracellular P02 in human skeletal muscle
62. 1H-MRS evaluation of the phosphocreatine-creatine (PCr/Cr) pool in human muscle
63. 31P NMR studies ofcreatine kinase flux in M-creatine kinase-deficient mouse heart
64. Some new aspects of creatine kinase (CK): Compartmentation, structure, function, and regulation for cellular mitochondrial bioenergetics and physiology
65. Intracellular compartmentation, structure, and function of creatine kinase isozymes in tissues with high and fluctuating energy demands: The 'phosphocreatine circuit' for cellular energy homeostasis
66. Myoglobin and hemoglobin rotational diffusion in the cell
67. Metabolic compartmentation in living cells: Structural association of aldolase
68. Locust flight metabolism studied in vivo with 31P NMR spectroscopy
69. The concept of symmorphosis: A testable hypothesis of structure-function relationships
70. What determines the metabolic rate of vertebrate cells
71. Diffusion theory, the cell, and the synapse
72. Flight muscle function in Drosophila requires colocalization of glycolytic enzymes
73. Cytoplasmic motility reflects phagocytic activity in alveolar macrophages from dog lungs