31P NMR studies of creatine kinase flux in M-creatine kinase-deficient mouse heart

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 275, Issue 4 44-4, 1998, Pages

  Van Borsten, Ferdi A ^a   Nederhoff, Marcel G J ^a,b   Nicolay, Klaas ^b   Van Echteld, Gees J A ^b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

Author keywords

Energy metabolism; Enzyme kinetics; Magnetic resonance spectroscopy; Phosphocreatine; Transgenic mice

Indexed keywords

CREATINE KINASE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; DIAGNOSTIC AGENT; ISOENZYME; PHOSPHORUS;

ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; ENERGY METABOLISM; ENZYME DEFICIENCY; ENZYME KINETICS; HEART FUNCTION; HEART PERFORMANCE; HYDROLYSIS; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; ANIMAL; C57BL MOUSE; ENZYMOLOGY; GENETICS; HEART MUSCLE; HEART RATE; IN VITRO STUDY; METABOLISM; MOUSE MUTANT;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; CREATINE KINASE; HEART RATE; ISOENZYMES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIUM; PHOSPHOCREATINE; PHOSPHORUS;

EID: 33750860447     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1998.275.4.h1191     Document Type: Article

References (41)

1. Askenasy, N., M. Tassini, A. Vivi, and G. Navon. Intracellular volume measurement and detection of edema: multinuclear NMR studies of intact rat hearts during normothermic ischemia. Magn. Reson. Med. 33: 515-520, 1995.
2. Balaban, R. S., H. L. Kantor, L. A. Katz, and R. W. Briggs. Relation between work and phosphate metabolite in the in vivo paced mammalian heart. Science 232:1121-1123, 1986.
3. Bernt, E., H. U. Bergmeyer, and H. Moellering. Creatine. In: Methods of Enzymatic Analysis. New York: Academic, 1974, p. 1772-1776.
4. 31P NMR surface coil studies in brain, heart and skeletal muscle of the living rat. Biochemistry 26:6083-6090, 1987.
5. 31P NMR magnetization transfer study. J. Biol. Chem. 260:3512-3517, 1985.
6. Brindle, K. M. NMR methods for measuring enzyme kinetics. Prog. NMR Spectroscopy 20:257-293, 1988.
7. 31P NMR magnetization-transfer measurements of ATP turnover during steady-state isometric muscle contraction in the rat hind limb in vivo. Biochemistry 28:4887-4893, 1989.
8. 31P NMR measurements of myocardial pH in vivo. Biochem. Biophys. Res. Commun. 151: 70-77, 1988.
9. Chance, B., J. S. Leigh, B. J. Clark, J. Maris, J. Kent, S. Nioka, and D. Smith. Control of oxidative metabolism and oxygen delivery in human skeletal muscle: a steady state analysis of the work/energy cost transfer function. Proc. Natl. Acad. Sci. USA 82:8384-8388, 1985.
10. Eijgelshoven, M. H. J., J. H. G. M. Van Beek, I. Mottet, M. G. J. Nederhoff, C. J. A. Van Echteld, and N. Westerhof. Cardiac high-energy phosphates adapt faster than oxygen consumption to changes in heart rate. Circ. Res. 75: 751-759, 1994.
11. Forsen, F., and R. A. Hoffman. Study of moderately rapid chemical exchange reactions by means of nuclear magnetic double resonance. J. Chem. Phys. 39:2892-2901, 1963.
12. From, A. H. L., S. D. Zimmer, S. P. Michurski, P. Mohanakrishnan, V. K. Ulstad, W. J. Thoma, and K. Ugurbil. Regulation of the oxidative phosphorylation rate in the intact cell. Biochemistry 29:3731-3743, 1990.
13. 31P NMR kinetics study of cardiac metabolism under mild hypoxia. J. Magn. Reson. 106:212-219, 1995.
14. Hearse, D. J., S. M. Humphrey, A. B. T. J. Boink, and T. J. C. Ruigrok. The calcium paradox: metabolic, electrophysiological, contractile and ultrastructural characteristics in four species. Eur. J. Cardiol. 7:241-256, 1978.
15. Jacobus, W. E., and V. A. Saks. Creatine kinase of heart mitochondria. Changes in its kinetic properties induced by coupling to oxidative phosphorylation. Arch. Biochem. Biophys. 219:167-178, 1982.
16. Jeffrey, F. M. H., and C. R. Malloy. Respiratory control and substrate effects in the working heart. Biochem. J. 287:117-123, 1992.
17. 31P NMR and NADH fluorescence study. FEBS Lett. 221: 270-276, 1987.
18. Katz, L. A., J. A, Swain, M. A. Portman, and R. S. Balaban. Relation between phosphate metabolites and oxygen consumption of heart in vivo. Am. J. Physiol. 256 (Heart Circ. Physiol. 25): H265-H274, 1989.
19. 31P NMR studies of ATP synthesis and hydrolysis kinetics in the intact myocardium. Biochemistry 26: 7501-7510, 1987.
20. Kirkels, J. H., C. J. A. Van Echteld, and T. J. C. Ruigrok. Intracellular magnesium during myocardial ischemia and reperfusion: possible consequences for postischemic recovery. J. Mol. Cell. Cardiol. 21:1209-1218, 1989.
21. Koretsky, A. P. Insights into cellular energy metabolism from transgenic mice. Physiol. Rev. 75: 667-688, 1995.
22. Kupriyanov, V. V., A. Y. Steinschneider, E. K. Ruuge, V. I. Kapel'ko, M. Y. Zueva, V. I. Lakomkin, V. N. Smirnov, and V. A. Saks. Regulation of energy flux through the creatine kinase reaction in vitro and in perfused rat heart. Biochim. Biophys. Ada 805:319-331, 1984.
23. Kushmerick, M. J., and R. A- Meyer. Chemical changes in rat leg muscle by phosphorus nuclear magnetic resonance. Am. J. Physiol. 248 (CellPhysiol. 17): C542-C549, 1985.
24. Lamprecht, W., and I. Trautschold. ATP. In: Methods of Enzymatic Analysis. New York: Academic, 1974, p. 2101-2110.
25. 2+ on the Xeq of the creatine kinase reaction and other phosphate hydrolyses and phosphate transfer reactions. J. Biol. Chem. 254: 6528-6537, 1979.
26. 31P-NMR saturation transfer study of the regulation of creatine kinase in rat heart. Biochim. Biophys. Acta 721: 312-320, 1982.
27. Meyer, R. A., H. L. Sweeney, and M. J. Kushmerick. A simple analysis of the "phosphocreatine shuttle." Am. J. Physiol. 246 (Cell Physiol. 15): C365-C377, 1984.
28. 31P-NMR magnetization transfer study of the isolated ferret heart. Circ. Res. 63:1-15, 1988.
29. Perry, S. B., J. McAuliffe, J. A. Balschi, P. R. Hickey, and J. S. Ingwall. Velocity of the creatine kinase reaction in the neonatal rabbit heart: role of the mitochondrial creatine kinase. Biochemistry 27:2165-2172, 1988.
30. Saks, V.A., G. B. Chernousova, R. Vetter, V. N. Smirnov, and E. I. Chazov. Kinetic properties and the functional role of the particulate MM-isoenzyme of creatine kinase bound to heart muscle myofibrils. FEBS Lett. 262:293-296, 1976.
31. Shoubridge, E. A., J. L. Bland, and G. K. Radda. Regulation of creatine kinase during steady-state isometric twitch contraction in rat skeletal muscle. Biochim. Biophys. Acta 805: 72-78, 1984.
32. 31P NMR signals using the variable projection method and prior knowledge. Magn. Reson. Med. 6: 92-98, 1988.
33. Van Deursen, J., A. Heerschap, F. Oerlemans, W. Ruitenbcek, P. Jap, H. Ter Laak, and B. Wieringa. Skeletal muscles of mice deficient in muscle creatine kinase lack burst activity. Cell 74: 621-631, 1993.
34. Van Deursen, J., W. Ruitenbeek, A. Heerschap, P. Jap, H. Ter Laak, and B. Wieringa. Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression. Proc. Natl. Acad. Sci. USA 91:9091-9095, 1994.
35. 31P-NMR. Biochim. Biophys. Acta 1274:59-66, 1996.
36. Veksler, V. I., A. V. Kuznetsov, K. Anflous, P. Mateo, J. Van Deursen, B. Wieringa, and R. Ventura-CIapier. Muscle creatine kinase-deficient mice. II. Cardiac and skeletal muscles exhibit tissue-specific adaptation of the mitochondrial function. J. Biol. Chem. 270:19921-19929, 1995.
37. Ventura-CIapier, R., A. V. Kuznetsov, A. D'Albis, J. Van Deursen, B. Wieringa, and V. I. Veksler. Muscle creatine kinase-deficient mice. I. Alterations in myofibrillar function. J. Biol. Chem. 270:19914-19920, 1995.
38. Wallimann, T., M. Wyss, D. Brdiczka, K. Nicolay, and H. M. Eppenberger. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the "phosphocreatine circuit" for cellular energy homeostasis. Biochem. J. 281:21-40, 1992.
39. Wyss, M., J. Smeitink, R. A. Wevers, and T. Wallimann. Mitochondrial creatine kinase: a key enzyme of aerobic energy metabolism. Biochim. Biophys. Acta 1102:119-166, 1992.
40. Zahler, R., and J. Ingwall. Estimation of heart mitochondrial creatine kinase flux using magnetization transfer NMR spectroscopy. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H1022-H1028, 1992.
41. Zweier, J. L., and W. E. Jacobus. Substrate-induced alterations of high energy phosphate metabolism and contractile function in the perfused heart. J. Biol. Chem. 262: 8015-8021, 1987.