Cellular consequences upon factor VIIa binding to tissue factor

Haemostasis

Volumn 30, Issue SUPPL. 2, 2000, Pages 41-47

  Siegbahn, Agneta ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Angiogenesis; Cancer metastasis; Cell migration; Coagulation activation; Signal transduction; Tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 7A; ENZYME PRECURSOR; GLYCOPROTEIN; THROMBOPLASTIN;

ADVENTITIA; ANGIOGENESIS; BLOOD CLOTTING; CELL ADHESION; CELL MIGRATION; COMPLEMENT ACTIVATION; CONFERENCE PAPER; ENDOTHELIUM CELL; EXTRAVASCULAR SPACE; HUMAN; METASTASIS; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

EID: 0034459606     PISSN: 03010147     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054162     Document Type: Conference Paper

References (34)

1. Cell biology of tissue factor, the principal initiator of blood coagulation
2. Platelet-derived growth factor-BB and monocyte chemotactic protein-1 induce human peripheral blood monocytes to express tissue factor
3. Cellular interactions in tissue factor expression by blood monocytes
4. CD40 engagement on endothelial cells promotes tissue factor-dependent procoagulant activity
5. CD40 engagement induces monocyte procoagulant activity through an interleukin-10 resistent pathway
6. Coronary thrombosis
7. Anticoagulant effects of 1alpha, 25-dihydroxyvitamin D3 on human myelogenous leukaemia cells and monocytes
8. Cancer procoagulant and tissue factor are differently modulated by all-trans-retinoic acid in acute promyelocytic leukemia cells
9. Induction of differentiation in U-937 and NB4 cells is associated with inhibition of tissue factor production
10. Vascular permeability factor, fibrin, and the pathogenesis of tumor stroma formation
11. Tissue factor in cancer angiogenesis and metastasis
12. Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation
13. Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis
14. Expression of tissue factor correlates with grade of malignancy in human glioma
15. Expression of tissue factor in human stroma correlates with progression to invasive human breast cancer: Paracrine regulation by carcinoma cell-derived members of transforming growth factor β family
16. Tissue factor expression in human colorectal carcinoma. Correlation with hepatic metastasis and impact on prognosis
17. Tissue factor: A new independent prognostic marker in breast cancer
18. Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice
19. Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis
20. Role of tissue factor in metastasis: Functions of the cytoplasmic and extracellular domains of the molecule
21. Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor
22. 2+ signals in J82 cells, transfected COS-1 cells, Madin-Darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor
23. 2+ oscillations in Madin-Darby canine kidney cells only when proteolytically active
24. Signal transduction via the mitogen-activated protein kinase pathway induced by binding of coagulation factor VIIa to tissue factor
25. Coagulation factors VIIa and Xa induce cell signaling leading to up-regulation of the egr-1 gene
26. Binding of FVIIa to tissue factor induces alterations in gene expression in human fibroblast cells: Up-regulation of poly(A) polymerase
27. Enhanced expression of urokinase receptor induced through the tissue factor-factor VIIa pathway in human pancreatic cancer
28. Binding of factor VIIa to tissue factor on keratinocytes induces gene expression
29. Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa tissue factor-induced signal transduction
30. A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280
31. Tissue factor induces migration of cultured aortic smooth muscle cells
32. Binding of factor VIIa to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB stimulated chemotaxis
33. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa
34. Exclusion of known protease activated receptors in factor VIIa-induced signal transduction