Growth hormone (GH) replacement is not justified for all adults with GH deficiency

Journal of Clinical Endocrinology and Metabolism

Volumn 85, Issue 3, 2000, Pages 937-939

  Shalet, S M ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN C;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DRUG COST; FRACTURE; GROWTH HORMONE DEFICIENCY; HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; HYPOPITUITARISM; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; QUALITY OF LIFE; RISK ASSESSMENT;

EID: 0034453009     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.85.3.6487-2     Document Type: Article

References (28)

1. The effects of treatment with recombinant growth hormone on body composition and metabolism in adults with growth hormone deficiency
2. Body composition in adult growth hormone deficient men, assessed by anthropometry and bioimpedance analysis
3. Long-term follow-up of hypopituitary patients treated with human growth hormone
4. Growth hormone treatment improves serum lipids and lipoproteins in adults with growth hormone deficiency
5. High fibrinogen and plasminogen activator inhibitor activity in growth hormone deficient adults
6. Growth hormone deficient adults are insulin resistant
7. Left ventricular function in young adults with childhood and adulthood onset growth hormone deficiency
8. Growth hormone and the cardiovascular system
9. Detection of premature atherosclerosis by high-resolution ultrasonography in symptom-free hypopituitary adults
10. Premature mortality due to cardiovascular disease in hypopituitarism
11. Increased cerebrovascular mortality in patients with hypopituitarism
12. Long-term growth hormone treatment increases bone mineral content and density in patients with adult-onset growth hormone deficiency
13. Growth hormone status in adults treated for acute lymphoblastic leukaemia in childhood
14. Diagnosis of growth hormone deficiency in adults
15. Increased mortality in hypopituitarism is not due to an increase in vascular mortality
16. Growth hormone treatment of growth hormone deficient adults results in a marked increase in Lp(a) and HDL cholesterol concentrations
17. Cardiovascular risk factors in growth hormone deficient adults
18. Normal bone mineral density in patients with adult onset GH deficiency
19. Elderly patients with organic growth hormone (GH) deficiency are not osteopenic
20. Characteristics of adults who wish to enter a trial of growth hormone replacement
21. Factors influencing the desire for long term growth hormone replacement in adults
22. Decreased psychological well-being in adult patients with growth hormone deficiency
23. Quality of life assessment of adults with growth hormone deficiency. Implications for drug therapy
24. Dose titration and patient selection increases the efficacy of GH replacement in severely GHD adults
25. Optimizing growth hormone replacement therapy by dose titration in hypopituitary adults
26. Effects of physiological growth hormone (GH) therapy on cognition and quality of life in patients with adult onset GH deficiency
27. Beneficial effects of growth hormone treatment in GH-deficient adults
28. The effects of treatment with recombinant human growth hormone on body composition in adults with growth hormone deficiency