DNA damage recognition and nucleotide excision repair in mammalian cells

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 65, Issue , 2000, Pages 173-182

  Wood, R D ^a   Araujo S J ^a   Ariza, R R ^a   Batty, D P ^a   Biggerstaff, M ^a   Evans, E ^a   Gaillard, P H ^a   Gunz, D ^a   Koberle B ^a   Kuraoka, I ^a   Moggs, J G ^a   Sandall, J K ^a   Shivji, M K K ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NUCLEOTIDE; PROTEIN; RNA POLYMERASE II; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP C PROTEIN; XPE PROTEIN; TRANSCRIPTION FACTOR;

CELL CYCLE; CONFERENCE PAPER; DNA ADDUCT; DNA BINDING; DNA CROSS LINKING; DNA DAMAGE; DNA REPAIR; DNA STRUCTURE; EXCISION REPAIR; GENE TRANSLOCATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS; ARTICLE; EXPERIMENTAL MODEL; MAMMAL CELL; MOLECULAR RECOGNITION; PROTEIN SYNTHESIS; ULTRAVIOLET RADIATION; ANIMAL; GENETICS; MAMMAL; METABOLISM; REVIEW;

MAMMALIA;

ANIMAL; DNA; DNA DAMAGE; DNA REPAIR; HUMAN; MAMMALS; TRANSCRIPTION FACTORS;

EID: 0034437982     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2000.65.173     Document Type: Conference Paper

References (75)

1. Mammalian DNA nucleotide excision repair reconstituted with purified protein components
2. Purification of an ultraviolet-inducible, damage-specific DNA-binding protein from primate cells
3. Reconstitution of damage DNA excision reaction from SV40 minichromosomes with purified nucleotide excision repair proteins
4. Protein complexes in nucleotide excision repair
5. Nucleotide excision repair of DNA with recombinant human proteins: Definition of the minimal set of factors, active forms of TFIIH and modulation by CAK
6. Damage recognition in nucleotide excision repair of DNA
7. Stable binding of human XPC-hHR23B complex to irradiated DNA confers strong discrimination for damaged sites
8. Hepatitis-B virus X protein interferes with cellular DNA repair
9. DNA unwinding produced by site-specific intrastrand crosslinks of the antitumor drug cis-diamminedichloroplatinum(II)
10. UV damage causes uncontrolled DNA breakage in cells from patients with combined features of XPD and Cockayne syndrome
11. Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex
12. Recognition of nonhybridizing base pairs during nucleotide excision repair of DNA
13. Properties of damage-dependent DNA incision by nucleotide excision-repair in human cell-free-extracts
14. Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA
15. Conserved residues of human XPG protein important for nuclease activity and function in nucleotide excision repair
16. The organization of replication and transcription
17. DNA-binding polarity of human replication protein-A positions nucleases in nucleotide excision-repair
18. Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein
19. Mechanism of open complex and dual incision formation by human nucleotide excision repair factors
20. A DNA binding protein from human placenta specific for ultraviolet damaged DNA
21. Characterization of DNA recognition by the human UV-damaged DNA-binding protein
22. Affinity of yeast nucleotide excision repair factor 2, consisting of the Rad4 and Rad23 proteins, for ultraviolet damaged DNA
23. DDB, a putative DNA-repair protein, can function as a transcriptional partner of E2F1
24. Base-pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision-repair enzymes
25. Bipartite substrate discrimination by human nucleotide excision-repair
26. A constitutive damage-specific DNA-binding protein is synthesized at higher levels in UV-irradiated primate cells
27. Interaction of hHR23 with S5a - The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome
28. Action of DNA repair endonuclease ERCC1/XPF in living cells
29. P48 activates a UV-damaged-DNA binding-factor and is defective in xeroderma pigmentosum group-E cells that lack binding activity
30. Preferential binding of yeast Rad4-Rad23 complex to damaged DNA
31. Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA
32. Characterization of a human DNA-damage binding protein implicated in xeroderma pigmentosum E
33. Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage binding protein
34. Contrasting structural impacts induced by cis-syn cyclobutane dimer and (6-4)adduct in DNA duplex decamers: Implication in mutagenesis and repair activity
35. Defective repair of cisplatin-induced DNA damage caused by reduced XPA protein in testicular germ cell tumours
36. Removal of oxygen free-radical induced 5′,8 purine cyclodeoxynucleosides from DNA by the nucleotide excision repair pathway in human cells
37. XPC interacts with both HHR23B and HHR23A in vivo
38. Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23
39. The biology of the (6-4) photoproduct
40. Differential human nucleotide excision repair of paired and mispaired cisplatin-DNA adducts
41. Model for XPC-independent transcription-coupled repair of pyrimidine dimers in humans
42. Reaction-mechanism of human DNA-repair excision nuclease
43. Characterization of reaction intermediates of human excision-repair nuclease
44. Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision-repair systems
45. Enzymology of human nucleotide excision repair
46. The DNA helicase and adenosine-triphosphatase activities of yeast Rad3 protein are inhibited by DNA damage - A potential mechanism for damage-specific recognition
47. Inhibition of Rad3 DNA helicase activity by DNA adducts and abasic sites - Implications for the role of a DNA helicase in damage-specific incision of DNA
48. Mutations specific to the xeroderma pigmentosum group-E DDB(-) phenotype
49. Translocation of a UV-damaged DNA-binding protein into a tight association with chromatin after treatment of mammalian-cells with UV-light
50. Relationship of the xeroderma pigmentosum group E DNA repair defect to the chromatin and DNA binding proteins UV-DDB and replication protein A
51. Xeroderma pigmentosum group-E binding-factor recognizes a broad spectrum of DNA damage
52. Lagging strand DNA synthesis by calf thymus DNA polymerases α, β, δ and ε in the presence of auxiliary proteins
53. Overproduction, purification, and characterization of the XPC subunit of the human DNA-repair excision nuclease
54. In-vitro repair of oxidative DNA-damage by human nucleotide excision-repair system - Possible explanation for neurodegeneration in xeroderma-pigmentosum patients
55. Comparative analysis of binding of human damaged DNA-binding protein (XPE) and Escherichia coli damage recognition protein (UvrA) to the major ultraviolet photoproducts - T[c,s]T, T[t,s]T, T[6-4]T, and T[Dewar]T
56. DNA excision repair
57. Conformation of DNA modified at a d(GG) or a d(AG) site by the antitumor drug cis-diamminedichloroplatinum(II)
58. A relationship between a DNA-repair/recombination nuclease family and archaeal helicases
59. Nucleotide excision repair DNA synthesis by DNA polymerase e in the presence of PCNA, RFC, and RPA
60. Cdn l
61. hHR23B, a human Rad23 homolog, stimulates XPC protein in nucleotide excision-repair in-vitro
62. Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair
63. Two human homologues of Rad23 are functionally interchangeable in complex formation and stimulation of XPC repair activity
64. Negative superhelicity promotes ATP-dependent binding of yeast Rad3 protein to ultraviolet-damaged DNA
65. Electron microscopy of DNA excision repair patches produced by human cell extracts
66. A 127 kDa component of a UV-damaged DNA-binding complex, which is defective in some xeroderma pigmentosum group E patients, is homologous to a slime-mold protein
67. Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis
68. XPC and human homologs of Rad23 - Intracellular-localization and relationship to other nucleotide excision-repair complexes
69. Xeroderma pigmentosum complementation group-C cells remove pyrimidine dimers selectively from the transcribed strand of active genes
70. Order of assembly of human DNA repair excision nuclease
71. The non-catalytic function of XPG protein during dual incision in human nucleotide excision repair
72. TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair
73. DNA repair in eukaryotes
74. Nucleotide excision repair of DNA by mammalian cell extracts and purified proteins
75. The xeroderma pigmentosum group C protein complex XPC-HR23B plays an important role in the recruitment of transcription factor IIH to damaged DNA