Fluoride ion-mediated intramolecular aldol cyclization of 7-(t-butyldimethylsiloxy)-7-octenal

Chemistry Letters

Volumn , Issue 8, 2000, Pages 932-933

  Hachiya, Iwao ^a   Kobayashi, Nobutaka ^a   Kijima, Hiroyuki ^a   Pudhom, Khanitha ^a   Mukaiyama, Teruaki ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034337671     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.2000.932     Document Type: Article

References (25)

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24. 4. The organic solvents were evaporated under reduced pressure and the crude product was purified by thin-layer chromatography on silica gel (hexane/ethyl acetate = 6/1) to afford 7a-α (12.6 mg, 6.7%), 7a-β (62.7 mg, 33.4%) in two steps from 5a. 6a-β′ was acetylated according to the above method to afford 7a-β′ (72.4 mg, 38.6%) in two steps from 5a.
25. No attempts have been made to optimize this reaction. Configuration assignment was not made.