Expression and subcellular localization of two isoforms of the survival motor neuron protein in different cell types

Journal of Neuroscience Research

Volumn 62, Issue 3, 2000, Pages 346-356

  La Bella, Vincenzo ^a   Kallenbach, Sacha ^a   Pettmann, Brigitte ^a  

^a AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

Bcl 2; Isoforms; Motoneurons; SMN; Subcellular localization

Indexed keywords

COMPLEMENTARY DNA; ISOPROTEIN; PROTEIN; PROTEIN BCL 2; SURVIVAL MOTOR NEURON PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; DISEASE ASSOCIATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SPINAL MUSCULAR ATROPHY;

3T3 CELLS; ANIMALS; ANTIBODY SPECIFICITY; CELL NUCLEUS; CELLS, CULTURED; COS CELLS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYTOSOL; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICROSCOPY, CONFOCAL; MOLECULAR WEIGHT; MOTOR NEURONS; NERVE TISSUE PROTEINS; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RNA-BINDING PROTEINS; SPINAL CORD; SUBCELLULAR FRACTIONS; TRANSFECTION;

EID: 0034331251     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4547(20001101)62:3<346::AID-JNR4>3.0.CO;2-D     Document Type: Article

References (48)

1. The caveolae membrane system
2. Human autoantibody to a novel protein of the nuclear coiled body: Immunological characterization and cDNA cloning of P80 coilin
3. Immunocytochemical analysis of the coiled body in the cell cycle find during proliferation
4. Cardiotrophin-1 requires LIFRβ to promote survival of mouse motoneurons purified by a novel technique
5. Expression of the SMN gene, the spinal muscular atrophy determining gene, in the mammalian central nervous system
6. Subcellular distribution of survival motor neuron (SMN) protein: Possible involvement in nucleocytoplasmic and dendritic transport
7. Molecular analysis of coiled bodies
8. The distribution of SMN protein complex in human fetal tissues and its alteration in spinal muscular atrophy
9. Un sencillo metodo de coloracion selectiva del reticulo protoplasmatico y sus efectos en los diversos organos nerviosos de vertebrados e invertebrados
10. Identification of caveolin and caveolin-related proteins in the brain
11. Assembly of snRNP-containing coiled bodies is regulated in interphase and mitosis-evidence that the coiled body is a kinetic nuclear structure
12. The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body
13. A monoclonal antibody modulates the interaction of nerve growth factor with PC12 cells
14. Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of Gems
15. Gemin4: A novel component of the SMN complex that is found in both Gems and nucleoli
16. The survival motor neuron protein in spinal muscular atrophy
17. The neurobiology of childhood spinal muscular atrophy
18. Cloning, characterization, and copy number of the murine survival motor neuron gene: Homolog of the spinal muscular atrophy-determining gene
19. The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis
20. Heterogeneity of subcellular localization and electrophoretic mobility of survival motor neuron (SMN) protein in mammalian neural cells and tissues
21. Association of snRNA genes with coiled bodies is mediated by nascent snRNA transcripts
22. Differential SMN2 expression associated with SMA severity
23. Survival motor neuron gene transcript analysis in muscles from spinal muscular atrophy patients
24. A role for polyproline motifs in the spinal muscular atrophy protein SMN
25. Purified embryonic motoneurons
26. A mouse model for spinal muscular atrophy
27. Spinal muscular atrophy
28. Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy
29. Looking at lipid rafts?
30. RNA-cytoskeletal associations
31. Survival motor neuron (SMN) protein in rat is expressed as different molecular forms and is developmentally regulated
32. The coiled body
33. Identification and characterization of a spinal muscular atrophy-determining gene
34. Correlation between severity and SMN protein level in spinal muscular atrophy
35. A novel nuclear structure containing the survival motor neuron protein
36. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins
37. The domain encoded by exon 2 of the survival motor neuron protein mediates nucleic acid binding
38. SMN oligomerization defect correlates with spinal muscular atrophy severity
39. Of coiled bodies, GEMS, and salmon
40. Coiled bodies and GEMS: Janus or Gemini?
41. Association between centromeric deletions of the SMN gene and sporadic adult-onset motor neuron disease
42. Subcellular localization and axonal transport of the survival motor neuron (SMN) protein in the developing rat spinal cord
43. A Novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing
44. Purification and characterization of proteins of heterogenous nuclear ribonucleoprotein complexes by affinity chromatography
45. Dynamic interactions between splicing snRNPs, coiled bodies and nucleoli revealed using snRNP protein fusions to the green fluorescent protein
46. Differential subcellular localization of the survival motor neuron protein in spinal cord and skeletal muscle
47. The survival motor neuron protein interacts with the transactivator FUSE binding protein from human fetal brain
48. An immunohistochemical study of the nerve growth factor receptor in developing rats