Ionization characteristics and chemical influences of aspartic acid residue 158 of papain and caricain determined by structure-related kinetic and computational techniques: Multiple electrostatic modulators of active-centre chemistry

Biochemical Journal

Volumn 351, Issue 3, 2000, Pages 723-733

  Noble, M A ^a   Gul, S ^a   Verma, C S ^a   Brocklehurst, K ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

4 chloro 7 nitrobenzofurazan; Cysteine proteinases; Poisson Boltzmann equation; Reactivity probe

Indexed keywords

4 CHLORO 7 NITROBENZOFURAZAN; ASPARTIC ACID; CYSTEINE PROTEINASE; PAPAIN;

ARTICLE; CHEMICAL REACTION KINETICS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; IONIZATION; NONHUMAN; PHYTOCHEMISTRY; PKA; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ASPARTIC ACID; BINDING SITES; CATALYTIC DOMAIN; COMPUTER SIMULATION; CYSTEINE ENDOPEPTIDASES; ELECTROSTATICS; IONS; KINETICS; MODELS, MOLECULAR; PAPAIN; PLANT PROTEINS; PROTEIN CONFORMATION;

EID: 0034329614     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3510723     Document Type: Article

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