Rates of glutathione synthesis in lung subcompartments of mice and monkeys: Possible role in species and site selective injury

Journal of Pharmacology and Experimental Therapeutics

Volumn 277, Issue 3, 1996, Pages 1402-1409

  Duan, Xiuzhen ^a,c   Plopper, Charles ^a,b   Brennan, Patricia ^a   Buckpitt, Alan ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; GLUTATHIONE; MALEIC ACID DIETHYL ESTER; XENOBIOTIC AGENT;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BRONCHIOLE; CONTROLLED STUDY; LUNG TOXICITY; MALE; MOUSE; NONHUMAN; PARENCHYMA; PRIORITY JOURNAL; RHESUS MONKEY; SPECIES DIFFERENCE; TRACHEA;

ANIMALS; EPITHELIUM; GLUTATHIONE; LUNG; MACACA; MALE; MICE; MICE, INBRED STRAINS; TRACHEA;

EID: 0030438478     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. ADAMSON, G. M. AND HARMAN, A. W.: Comparison of the susceptibility of hepatocytes from postnatal and adult mice to hepatotoxins. Biochem. Pharmacol. 37:4183-4190, 1988.
2. BAI, C., BEOWN, L. AND JONES, D.: Glutathione transport by type II cells in perfused rat lung. Am. J. Physiol. 267: L447-455, 1994.
3. BEIERSCHMITT, W. P., BRADY, J. T., BARTOLONE, J. B., WYAND, D. S., KHAIRALLAH, E. A. AND COHEN, S. D.: Selective protein arylation and the age dependency of acetaminophen hepatotoxicity in mice. Toxicol. Appl. Pharmacol. 98: 517-529, 1989.
4. BERGGREN, M., DAWSON, J. AND MOLDEUS, P.: Glutathione biosynthesis in the isolated perfused rat lung: Utilization of extracellular glutathione. FEBS Lett. 7: 189-192, 1984.
5. BOYD, M. R.: Biological mechanisms in chemical induced lung injury: Role of metabolic activation. CRC Crit. Rev. Toxicol. 7:103-176, 1980.
6. BROWN, L., BAI, C. AND JONES, D.: Glutathione protection from alveolar type II cells from fetal and neonatal rabbits. Am. J. Physiol. 262: L305-312, 1992.
7. CHICHESTER, C., BUCKPITT, A. AND PLOPPER, C.: Glutathione pools in isolated murine Clara cells: Effects of naphthalene. Toxicologist 14:180, 1994.
8. DUAN, X., BUCKPITT, A. AND PLOPPER, C.: Variation in antioxidant enzyme activities in anatomic subcompartments of the rat and rhesus monkey lung. Toxicol. Appl. Pharmacol. 123: 73-82, 1993.
9. FAHEY, R. AND NEWTON, G.: Determination of low-molecular weight thiols using monobromobimane fluorescent labelling and high performance liquid chromatography. In Methods of Enzymology, vol 143, ed. by W. Jakoby and O. Griffith, pp. 85-96, Academic Press, New York, 1987.
10. HAGEN, T., BROWN, L., JONES, D.: Protection against paraquat induced injury by exogenous GSH in pulmonary alveolar type II cells. Biochem. Pharmacol. 35: 4537-4542, 1986.
11. HORTON, J. K., MEREDITH, M. J. AND BEND, J. R.: Glutathione biosynthesis from sulfur-containing amino acids in enriched populations of Clara and type II cells and macrophages freshly isolated from rabbit lung. J. Pharmcol. Exp. Ther. 240: 376-380, 1987.
12. Hu, S. C., BEN-JEBBIA, A. AND ULTMAN, J. S.: Longitudinal distribution of ozone absorption in the lung: Quiet respiration in healthy subjects. J. Appl. Physiol. 73:1655-1661, 1992.
13. JOSHI, U. M., DUMAS, M. AND MEHENDALE, H. M.: Glutathione turnover in perfused rabbit lung. Effect of external glutathione. Biochem. Pharmacol. 35: 3412-3414, 1986.
14. JOSHI, U. M., KODAVANTI, P. R. MEHENDALE, H. M.: Glutathione metabolism and utilization of external thiols by cigarette smoke-challenged, isolated rat and rabbit lungs. Toxicol. Appl. Pharmacol. 96: 524-325, 1988.
15. KANEKAL, S., PLOPPER, C., MORIN, D. AND BUCKPITT, A. R.: Metabolic activation and bronchiolar Clara cell necrosis from naphthalene in the isolated perfused mouse lung. J. Pharmacol. Exp. Ther. 262: 428-437, 1990.
16. KANEKAL, S., PLOPPER, C. G., MORIN, D. AND BUCKPITT, A. R.: Metabolism and cytotoxicity of naphthalene oxide in the isolated perfused mouse lung. J. Pharmacol. Exp. Ther. 256: 391-401, 1991.
17. LASH, L., HAGEN, T. M. AND JONES, D. P.: Exogenous glutathione protects intestinal epithelial cells from oxidative injury. Proc. Natl. Acad. Sci. U.S.A. 83: 4641-4645, 1986.
18. LAUTERBURG, B. H., VAISHNAV, Y., STILLWELL W. G., MITCHELL J. R.: The effects of age and glutathione depletion on hepatic glutathione turnover in vivo determined by acetaminophen probe analysis. J. Pharmacol. Exp. Ther. 213: 54-58, 1980.
19. LOWRY, O. H., ROSEBROUGH, N. J., FARR, A. L. AND RANDALL, R. J.: Protein measurement with the Folin-phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
20. NIKULA, K., WILSON, D. W., DUNGWOKTH, D. AND PLOPPER, C. G.: In vitro evidence of cellular adaptation to ozone toxicity in the rat trachea. Toxicol. Appl. Pharmacol. 93: 394-402, 1988a.
21. O'BRIEN, K A. F., SUVERKROPP, C., KANEKAL, S., PLOPPER, C. G. AND BUCKPITT, A. R.: Tolerance to multiple doses of the pulmonary toxicant, naphthalene. Toxicol. Appl. Pharmacol. 99: 487-500, 1989.
22. PEACOCK, M. D., SCHENK, D. A., LAWRENCE, R. A., MORGAN, J. A. AND JENKINSON, S. G.: Elimination of glutathione-induced protection from hyperbaric hyperoxia by acivicin. J. Appl. Physiol. 76:1279-1284, 1994.
23. PICKETT, C. B.: Glutathione S-transferases: Gene structure, regulation, and biological function. Ann. Rev. Biochem. 58: 743-764, 1989.
24. PINKERTON, K., GHEHR, P. AND CRAPO, J.: Architecture and cellular composition of the air-blood barrier. In Comparative Biology of the Normal Lung, ed. by R. A. Parent, pp. 121-128, CRC Press, Boca Raton, FL, 1991.
25. PLOPPER, C. G.: Pulmonary bronchiolar epithelial cytotoxicity: microanatomical considerations. In Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells, ed. by T. E. Gram, Pergamon Press, Ltd, 1993.
26. PLOPPER, C. G., CHANG, A., PANG, A. AND BUCKPITT, A.: Use of microdissected airways to define metabolism and cytotoxicity in murine bronchiolar epithelium. Exp. Lung Res. 17: 181-196, 1991a.
27. PLOPPER, C. G., HARKEMA, J., LAST, J., PINKERTON, K., TYLER, W., STGEORGE, J., WONG, V., NISHIO, S., WEIR, A., DUNGWORTH, D., BARRY, B. AND HYDE, D.: The respiratory system of nonhuman primates responds more to ambient concentrations of ozone than does that of rats. In Trophospheric Ozone and the Environment, ed. by R. Bergland, D. Lawson and D. McKee, pp. 137-150. Air and Waste Management Association, Pittsburg, PA, 1991b.
28. PLOPPER, C. G., MACKLIN, J., NISHIO, S., HYDE, D. AND BUCKPITT, A.: Relationship of cytochrome P450 activity to Clara cell cytotoxicity. III. Morphometric comparisons of changes in the epithelial populations of terminal bronchioles and lobar bronchi in mice, hamsters and rats after parenteral administration of naphthalene. Lab. Invest. 67: 553-565, 1992.
29. PLOPPER, C., WEIR, A., NISHIO, S., CHANG, A., VOIT, M., PHILPOT, R. AND BUCKPITT, A.: Elevated susceptibility to 4-ipomeanol cytotoxicity in immature Clara cells of neonatal rabbits. J. Pharmacol. Exp. Ther. 269: 867-880, 1994.
30. POTTER, D. W. AND TRAN, T. B.: Apparent rate of glutathione turnover in rat tissues. Toxicol. Appl. Pharmacol. 120:186-192, 1993.
31. REED, D. J.: Glutathione: Toxicological implications. Annual Review of Pharmacology and Toxicology, ed. R. George, A. Cho and T. Blaschke, pp. 603-631, Annual Review Inc., Palo Alto, CA, 1990.
32. SERABJIT-SINGH, C. J., WOLF, C. R., PHILPOT, R. M. AND PLOPPER, C. G.: Cytochrome P450: Localization in rabbit lung, Science 207: 1469-1470, 1980.
33. STEPHENS, R. J., SLOAN, M. F., EVANS, M. J. AND FREEMAN, G.: Early response of lungs to low levels of ozone. Am. J. Pathol. 74: 31-44, 1974.
34. SUN, J. D., PICKRELL, J. A., HARKEMA, J. A., MCLAULIN, S. I., HAHN, F. F. AND HENDERSON, R. P.: Effects of buthionine sulfoximine on the development of ozone-induced pulmonary fibrosis. Exp. Mol. Path. 49: 254-266, 1988.
35. WEBER, C. A., DUNCAN, C. A., LYONS, M. J. AND JENKINSON, S. G.: Depletion of tissue glutathione with diethyl maleate enhances hyperbaric oxygen toxicity. Am. J. Physiol. 258: L308-L312, 1990.