S-methyl-N,N-diethylthiocarbamate sulfoxide and S-methyl-N,N-diethylthiocarbamate sulfone, two candidates for the active metabolite of disulfiram

Alcoholism: Clinical and Experimental Research

Volumn 20, Issue 3, 1996, Pages 595-600

  Mays, Dennis C ^a,b   Nelson, Albert N ^a   Lam Holt, Jennifer ^a   Fauq, Abdul H ^a   Lipsky, James J ^a,b  

^a Division of Clinical Pharmacology   (United States)

^b MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

Aldehyde Dehydrogenase; Disulfiram; Disulfiram Ethanol Reaction; Enzyme Inactivation

Indexed keywords

ALDEHYDE DEHYDROGENASE; DIETHYLDITHIOCARBAMIC ACID METHYL ESTER; DISULFIRAM;

ALCOHOLISM; ANIMAL EXPERIMENT; ARTICLE; AVERSION THERAPY; CONCENTRATION RESPONSE; DRUG CONFORMATION; DRUG EFFECT; DRUG METABOLISM; ENZYME INACTIVATION; LIVER MICROSOME METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ALCOHOL DETERRENTS; ALDEHYDE DEHYDROGENASE; ANIMALS; BIOTRANSFORMATION; DISULFIRAM; DITIOCARB; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUTATHIONE; LIVER; MALE; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029924629     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1996.tb01099.x     Document Type: Article

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