Increased type II transforming growth factor-β receptor expression in liver cells during cholesterol challenge

Atherosclerosis

Volumn 152, Issue 1, 2000, Pages 51-57

  Baccante, Giovanna ^a   Mincione, Gabriella ^a   Di Febbo, Concetta ^a   Coppa, Anna ^b   Angelucci, Domenico ^a   Lapenna, Domenico ^a   Cuccurullo, Franco ^a   Colletta, Giulia ^a   Porreca, Ettore ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Atherosclerosis; Cholesterol; Transforming growth factor receptors

Indexed keywords

CHOLESTEROL; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROGENIC DIET; ATHEROSCLEROSIS; CELL STRAIN HEPG2; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK FACTOR;

ANALYSIS OF VARIANCE; ANIMAL; ARTERIOSCLEROSIS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELLS, CULTURED; CHOLESTEROL; COMPARATIVE STUDY; DIET, ATHEROGENIC; HEPATOCYTES; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; PROBABILITY; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; STATISTICS, NONPARAMETRIC; SUPPORT, NON-U.S. GOV'T; UP-REGULATION;

EID: 0034283131     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(99)00449-9     Document Type: Article

References (30)

1. Border W.A., Ruoslahti E. Transforming growth factor-β in disease: the dark side of tissue repair. J. Clin. Invest. 90:1992;1-7.
2. Border W.A., Noble N.A. Transforming growth factor β in tissue fibrosis. New Engl. J. Med. 331:1994;1286-1292.
3. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 362:1993;801-809.
4. Gibbons G.H., Dzau V.J. The emerging concept of vascular remodeling. New Engl. J. Med. 330:1994;1431-1438.
5. Massagué J. Transforming growth factor-beta family. Annu. Rev. Cell Biol. 6:1990;597-641.
6. Dijke P., Miyazono K., Heldin C.H. Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Curr. Opin. Cell Biol. 8:1996;139-145.
7. Graff J.M., Bansal A., Melton D.A. Xenopus MAD proteins transduce distinct subsets of signals for the TGF-β superfamily. Cell. 85:1996;479-487.
8. Lòpez-Candales A., Scott M.J., Wickline S.A. Cholesterol feeding modulates spatial expression of TGF-β1 and β2 in aortas of Watanabe rabbits. Cytokine. 7:1995;554-561.
9. Ross R., Masuda J., Raines E.W., Gown A.M., Katsuda S., Sasahara M. et al. Localization of PDGF-B protein in macrophages in all stages of atherogenesis. Science. 248:1990;1009-1012.
10. Ding G., Pesek-Diamond I., Diamond J.R. Cholesterol, macrophages, and gene expression of TGF-β1 and fibronectin during nephrosis. Am. J. Physiol. 264:1993;577-584.
11. Eddy A.A. Interstitial inflammation and fibrosis in rats with diet-induced hypercholesterolemia. Kidney Int. 50:1996;1139-1149.
12. Moorby C.D., Gherardi E., Dovey L., Godliman C., Bowyer D.E. Transforming growth factor-β1 and interleukin-1β stimulate LDL receptor activity in HepG2 cells. Atherosclerosis. 97:1992;21-28.
13. Nicholson A.C., Hajjar D.P. Transforming growth factor-beta up-regulates low density lipoprotein receptor-mediated cholesterol metabolism in vascular smooth muscle cells. J. Biol. Chem. 267:1992;25982-25987.
14. Breslow J.L. Mouse model of atherosclerosis. Science. 272:1996;685-688.
15. Liao F., Andalibi A., deBeer F.C., Fogelman A.M., Lusis A.J. Genetic control of inflammatory gene induction and NF-kB-like transcription factor activation in response to an atherogenic diet in mice. J. Clin. Invest. 91:1993;2572-2579.
16. Hayashi H., Abdollah S., Qui Y., Cai J., Xu Y.Y., Grinnell B.W. et al. The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. Cell. 89:1997;1165-1173.
17. Javitt N.B. Hep G2 cells as a resource for metabolic studies: lipoprotein, cholesterol, and bile acids. FASEB J. 4:1990;161-168.
18. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocynate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
19. Lin H.Y., Wang X.F., Ng-Eaton E., Weinberg R.A., Lodish H.F. Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell. 68:1992;775-785.
20. Porreca E., Ucchino S., Di Febbo C., Di Bartolomeo N., Angelucci D., Napolitano A.M. et al. Antiproliferative effect of desferrioxamine on vascular smooth muscle cells in vitro and in vivo. Arterioscler. Thromb. 14:1994;294-299.
21. Binsack R., Stegmeier K., Dorge L., Volkl A. Bezafibrate down regulates fibrinogen biosynthesis in human hepatoma HepG2 cells. Eur. J. Clin. Invest. 2:1998;151-163.
22. Turco A., Coppa A., Scarpa S., Palumbo C., Baccheschi G., Colletta G. Overexpression of TbRII receptor in neuroblastoma cells reduces growth rate and induces neuronal differentiate phenotype. Int. J. Cancer. 80:1998;85-91.
23. Càrcamo J., Weis F.M.B., Ventura F., Weiser R., Wrana J.L., Attisano L. et al. Type I receptor specifity growth inhibitory and transcriptional responses to TGF-β and activin. Mol. Cell. Biol. 14:1994;3810-3821.
24. Taipale J., Matikainen S., Hurme M., Keski-Oja J. Induction of transforming growth factor β1 and its receptor expression during myeloid leukemia cell differentiation. Cell Growth Differ. 5:1994;1309-1319.
25. Wells R.C., Yankelev H., Lin H.Y., Lodish H.F. Biosynthesis of the type I and type II TGF-β receptors. Implication for complex formation. J. Biol. Chem. 272:1997;11444-11451.
26. Brown M.S., Goldstein J.L. Lipoprotein receptors in the liver: control signals for plasma cholesterol traffic. J. Clin. Invest. 72:1983;743-747.
27. Carey D.J. Control of growth and differentiation of vascular cells by extracellular matrix proteins. Annu. Rev. Physiol. 53:1991;161-177.
28. Fair D.S., Marlar R.A. Biosynthesis and secretion of factor VII, protein C, protein S, and protein C inhibitor from a human hepatoma cell line. Blood. 67:1986;64-68.
29. Hopkins W.E., Fujii S., Sobel B.E. Synergistic induction of plasminogen activator inhibitor type-1 in HEP G2 cells by thrombin and transforming growth factor-beta. Blood. 79:1992;75-81.
30. Hassan J., Chelucci C., Peschle C., Sorrentino V. Transforming growth factor-β (TGF-β) inhibits expression of fibrinogen and factor VII in a hepatoma cell line. Thromb. Haemost. 67(4):1992;478-483.