Ligand-mediated induction of thymidylate synthase occurs by enzyme stabilization: Implications for autoregulation of translation

Journal of Biological Chemistry

Volumn 274, Issue 18, 1999, Pages 12544-12547

  Kitchens, Maria E ^a   Forsthoefel, Antonia M ^a   Rafique, Zubaid ^a   Spencer, H Trent ^a,b   Berger, Franklin G ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b South Carolina Cancer Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLOXURIDINE; FLOXURIDINE PHOSPHATE; FLUOROURACIL; LIGAND; THYMIDINE PHOSPHATE; THYMIDYLATE SYNTHASE; THYMIDYLATE SYNTHASE INHIBITOR;

ANIMAL CELL; ARTICLE; AUTOREGULATION; COLON TUMOR; CONTROLLED STUDY; DRUG TARGETING; ENZYME INDUCTION; ENZYME STABILITY; ENZYME SUBSTRATE; HAMSTER; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RNA TRANSLATION; TRANSLATION REGULATION; TUMOR CELL LINE;

BASE SEQUENCE; DNA PRIMERS; ENZYME STABILITY; FLOXURIDINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LIGANDS; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; THYMIDYLATE SYNTHASE; TUMOR CELLS, CULTURED;

ANIMALIA; CRICETINAE;

EID: 0033617219     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.18.12544     Document Type: Article

References (22)

1. Carreras, C. W., and Santi, D. V. (1995) Annu. Rev. Biochem. 64, 721-762
2. Ardalan, B., Cooney, D., and Macdonald, J. S. (1980) Adv. Pharmacol. Chemother. 17, 289-321
3. Heidelberger, C., Danenberg, P. V., and Moran, R. G. (1982) Adv. Enzymol. Relat. Areas Mol. Biol. 54, 57-119
4. Takemura, Y., and Jackman, A. L. (1996) Anti-Cancer Drugs 8, 3-16
5. Touroutoglou, N., and Pazdur, R. (1996) Clin. Cancer Res. 2, 227-243
6. Spears, C. P., Shahinian, A. H., Moran, R. G., Heidelberger, C., and Corbett, T. H. (1982) Cancer Res. 42, 450-456
7. Keyomarsi, K., and Moran, R. G. (1988) J. Biol. Chem. 263, 14402-14409
8. Swain, S. M., Lippman, M. E., Egan, E. F., Drake, J. C., Steinberg, S. M., and Allegra, C. J. (1989) J. Clin. Oncol. 7, 890-899
9. Chu, E., Koeller, D. M., Casey, J. L., Drake, J. C., Chabner, B. A., Elwood, P. C., Zinn, S., and Allegra, C. J. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 8977-8981
10. Chu, E., Koeller, D. M., Johnston, P. G., Zinn, S., and Allegra, C. J. (1993) Mol.. Pharmacol. 43, 527-533
11. Chu, E., Koeller, D., Koeller, D. M., Drake, J. C., Takimoto, C. H., Maley, G. F., Maley, F., and Allegra, C. J. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 517-521
12. Keyomarsi, K., Samet, J., Molnar, G., and Pardee, A. B. (1993) J. Biol. Chem. 268, 15142-15149
13. Chu, E., and Allegra, C. J. (1996) Bioessays 18, 191-198
14. Sonenberg, N. (1988) Prog. Nucleic Acid Res. Mol. Biol. 35, 173-207
15. Abdel Moshen, A.-W., Aull, J. L., Payne, D. M., and Daron, H. H. (1995) Biochemistry 34, 1669-1677
16. Cisneros, R. J., and Dunlap, R. B. (1990) Anal. Biochem. 186, 202-208
17. Reilly, R. T., Forsthoefel, A. M., and Berger, F. G. (1997) Arch. Biochem. Biophys. 342, 338-343
18. Palacios, R., Palmiter, R. D., and Schimke, R. T. (1972) J. Biol. Chem. 247, 2316-2321
19. Johannes, G. J., and Berger, F. G. (1992) J. Biol. Chem. 267, 10108-10115
20. Barbour, K. W., Hoganson, D. K., Berger, S. H., and Berger, F. G. (1992) Mol. Pharmacol. 42, 242-248
21. Nussbaum, R. L., Walmsley, R. M., Lesko, J. G., Airhart, S. D., and Ledbetter, D. H. (1985) Am. J. Hum. Genet. 37, 1192-1205
22. Washtien, W. L. (1984) Mol. Pharmacol. 25, 171-177