Targeted gene disruption of murine CD7

International Immunology

Volumn 9, Issue 12, 1997, Pages 1875-1883

  Bonilla, Francisco A ^a,b   Kokron, Cristina M ^a   Swinton, Paul ^a   Geha, Raif S ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Knockout mice; NK cells; T lymphocytes

Indexed keywords

CD7 ANTIGEN;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CALCIUM TRANSPORT; CYTOKINE RELEASE; GENE DISRUPTION; IMMUNE DEFICIENCY; IMMUNIZATION; LYMPHOCYTE PROLIFERATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN; T LYMPHOCYTE; THYMUS;

ANIMALS; ANTIGENS, CD7; BONE MARROW; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; ISOANTIGENS; KILLER CELLS, NATURAL; LYMPH NODES; LYMPHOCYTE SUBSETS; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MITOGENS; SPLEEN; T-LYMPHOCYTES; THYMUS GLAND;

EID: 0031441347     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/9.12.1875     Document Type: Article

References (44)

1. Sanchez, M. J., Meunch, M. O., Roncarolo, M. G., Lanier, L. L. and Phillips, J. H. 1994. Identification of a common T/natural killer cell progenitor in human fetal thymus. J. Exp. Med. 180:569.
2. - T cells represent a subset of normal human blood lymphocytes. J. Immunol. 150:2081.
3. Grumayer, E. R., Griesinger, F., Hummell, D. S., Brunning, R. D. and Kersey, J. H. 1991. Identification of novel B-lineage cells in human fetal bone marrow that coexpress CD7. Blood 77:64.
4. Barcena, A., Meunch, M. O., Galy, A. H. M., Cupp, J., Roncarolo, M. G., Phillips, J. H. and Spits, H, 1993. Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T- and myeloid-cell development. Blood 82:3401.
5. Rincon, M., Tugores, A. and Lopez-Botet, M. 1992. Cyclic AMP and calcium regulate at a transcriptional level the expression of the CD7 leukocyte differentiation antigen. J. Biol. Chem. 267:18026.
6. Morishima, Y., Kobayashe, M., Yang, S. Y., Collins, N. H., Hoffmann, M. K. and Dupont, B. 1982. Functionally different T lymphocyte subpopulations determined by their sensitivity to complement-dependent cell lysis with the monoclonal antibody 4A. J. Immunol. 129:1091.
7. Ware, R. E. and Haynes, B. F. 1993. T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms. Int. Immunol. 5:179.
8. Jung, L. K. L. and Fu, S. M. 1988. Effect of tumor promoter 12-O-tetradecanoyl-phorbol 13-acetate on CD7 expression by T lineage cells. Eur J. Immunol. 18:711.
9. Shimizu, Y., van Seventer, G. A., Ennis, E., Newman, W., Horgan, K. J. and Shaw, S. 1992. Crosslinking of the T cell-specific accessory molecules CD7 and CD28 modulates T cell adhesion. J. Exp. Med. 175:577.
10. Carrel, S., Salvi, S., Rafti, F., Favrot, M., Rapin, C. and Sekaly, R. P. 1991. Direct involvement of CD7 (gp40) in activation of TcR γ/δ T cells. Eur. J. Immunol. 21:1195.
11. Carrera, A., Rincon, M., Sanchez-Madrid, F., Lopez-Botet, M. and de Landazuri, M. O. 1988. Triggering of co-mitogenic signals in T cell proliferation by anti-LFA-1 (CD18, CD11a) LFA-3, and CD7 monoclonal antibodies. J. Immunol. 141:1919.
12. Rabinowich, H., Lin, W., Herberman, R. B. and Whiteside, T. L. 1994. Signaling via CD7 molecules on human NK cells. Induction of tyrosine phosphorylation and β1 integrin-mediated adhesion to fibronectin. J. Immunol. 153:3504.
13. Rabinowich, H., Pricop, L., Herberman, R. B. and Whiteside, T. L. 1994. Expression and function of CD7 molecule on human natural killer cells, J. Immunol. 152:517.
14. Lazarovits, A. I., Osman, N., Le Feuvre, C., Ley, S. C. and Crumpton, M. J. 1994. CD7 is associated with CDS and CD45 on human T cells. J. Immunol. 153:3956.
15. Chan, A. S. H., Reynolds, P. J. and Shimizu, Y 1994. Tyrosine kinase activity associated with the CD7 antigen: correlation with regulation of T cell integrin function. Eur. J. Immunol. 24:2602.
16. Ward, S. G., Parry, R., Le Feuvre, C., Sansom, D. M., Westwick, J. and Lazarovits, A. I. 1995. Antibody ligation of CD7 leads to association with phosphoinositide 3-kinase and phosphatidylinositol 3,4,5-triphosphate formation in T lymphocytes. Eur. J. Immunol. 25:502.
17. Lee, D. M., Patel, D. D., Pendergast, A. M. and Haynes, B. F. 1996. Functional association of CD7 with phosphatidylinositol 3-kinase: interaction via a YEDM motif. Int. Immunol. 8:1195.
18. Chatila, T. and Geha, R. S. 1988. Phosphorylation of T cell membrane proteins by activators of protein kinase C. J. Immunol. 140:4308.
19. Cerny, J., Stockinger, H. and Horejsi, V. 1996. Noncovalent associations of T lymphocyte surface proteins. Eur. J. Immunol. 26:2335.
20. Jung, L. K. L., Fu, S. M., Hara, T., Kapoor, N. and Good, R. A. 1986. Defective expression of T cell-associated glycoprotein in severe combined immunodeficiency. J. Clin. Invest. 77:940.
21. Scnanberg, L. E., Fleenor, D. E., Kurtzberg, J., Haynes, B. F. and Kaufman, R. E. 1991. Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene. Proc. Natl Acad. Sci. USA 88:603.
22. Yoshikawa, K., Seto, M., Ueda, R., Obata, Y., Notake, K., Yokochi, T. and Takahashi, T. 1991. Molecular cloning of the gene coding for the human T cell differentiation antigen CD7. Immunogenetics 33:352.
23. Yoshikawa, K., Seto, M., Ueda, R., Obata, Y., Aoki, S. and Takahashi, T. 1995. Molecular cloning of the gene coding for the mouse T-cell antigen CD7. Immunogenetics 41:159.
24. Lee, D. M., Watson, M. L. and Seldin, M. F. 1994. Mouse CD7 maps to chromosome 11. Immunogenetics 39:289.
25. Songyang, Z., Shoelson, S. E., Chaudhuri, M., Gish, G., Pawson, T., Haser, W. G., King, F., Roberts, T., Ratnofsky, S., Lechleider, R. J., Neel, B. G., Birge, R. B., Fajardo, J. E., Chou, M. M., Hanafusa, H., Schaffhausen, B. and Cantley, L. C. 1993. SH2 domains recognize specific phosphotyrosine sequences. Cell 72:767.
26. Yoshikawa, K., Seto, M., Ueda, R., Obata, Y., Fukatsu, H., Segawa, A. and Takahashi, T. 1993. Isolation and characterization of mouse CD7 cDNA. Immunogenetics 37:114.
27. Schanberg, L. E., Lee, D. M., Fleenor, D. E., Ware, R. E., Patel, D. D., Haynes, B. F. and Kaufman, R. E. 1995. Characterization of human CD7 transgenic mice. J. Immunol. 155:2407.
28. Tybulewicz, V. L. J., Crawford, C. E., Jackson, P. K., Bronson, R. T. and Mulligan, R. C. 1991. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 65:1153.
29. Li, E., Bestor, T. H. and Jaenisch, R. 1992. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell. 69:915.
30. Current Protocols on CD-ROM. 1997. Current Protocols in Immunology. ISBN 0-471-30661-4. John Wiley, Chichester.
31. Kiessling, R., Klein, E. and Wigzell, H. 1975. 'Natural' killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype Eur. J. Immunol. 5:112.
32. Moore, T. A., von Freeden-Jeffry, U., Murray, R. and Zlotnik, A. 1996. Inhibition of γδ T cell development and early thymocyte maturation in IL-7 -/- mice. J. Immunol. 157:2366.
33. Ybarrondo, B., Lazetic, S., Alaverdi, N., Gillette, L. and Shih, C 1997. The monoclonal antibody DX5 is specific for a pan NK cell surface marker. J. Allergy Clin. Immunol. 99:S293 (Abstr.).
34. Kokron, C. M., Bonilla, F. A., Oettgen, H. C. Ramesh, N., Geha, R. S. and Pandolfi, F. 1997. Searching for genes involved in the pathogenesis of primary immunodeficiency diseases: lessons from mouse knockouts. J. Clin. Immunol. 17:109.
35. Emara, M. and Carroll, R. G. 1992. Signal transduction through crosslinking CD7 and IgM-Fc receptors that inhibits T-cell proliferation. Hum. Immunol. 34:181.
36. Emara, M. and Sanfilippo, F. 1992. The inhibition of T cell proliferative responses by crosslinking CD7 and IgM-Fc receptors. Cell. Immunol. 144:143.
37. Lazarovits, A. I. and Karsh, J. 1988. A monoclonal antibody, 7G5 (CD7), induces modulation of Tp40 and inhibits proliferation in the allogeneic and autologous mixed lymphocyte reactions. Transplant. Proc. 20:1253.
38. Lazarovits, A. I. and Karsh, J. 1989. Modulation of CD7 is associated with inhibition of T cell proliferation in response to tetanus toxoid and phytohemagglutinin. Transplant. Proc. 21:3325.
39. Miyazaki, T., Dierich, A., Benoist, C. and Mathis, D. 1996. Independent modes of natural killing in mice lacking Lag3. Science 272:405.
40. Moll, M., Reinhold, U., Kukel, S., Abken, H., Muller, R., Oltermann, I. and Kreysel, H.-W 1994 CD7-negative helper T cells accumulate in inflammatory skin lesions. J. Invest. Dermatol. 102:328.
41. Lazarovits, A. I. and Karsh, J. 1988. Decreased expression of CD7 occurs in rheumatoid arthritis. Clin. Exp. Immunol. 72:470.
42. - T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J. Clin. Invest. 97:2027.
43. Tarakhovsky, A., Muller, W. and Rajewsky, K. 1994. Lymphocyte populations and immune responses in CD5-deficient mice. Eur. J. Immunol. 24:1678.
44. Tarakhovsky, A., Kanner, S. B., Hombach, J., Ledbetter, J. A., Muller, W., Killeen, N. and Rajewsky, K. 1995. A role for CD5 in TCR-mediated signal transduction and thymocyte selection. Science 269:535.