Adenosine- and 2-chloro-adenosine-induced cytopathic effects on myoblastic cells and myotubes: Involvement of different intracellular mechanisms

Neuromuscular Disorders

Volumn 10, Issue 6, 2000, Pages 436-446

  Ceruti, Stefania ^a   Giammarioli, Anna Maria ^b   Camurri, Alessandra ^a   Falzano, Loredana ^b   Rufini, Stefano ^c   Frank, Claudio ^b   Fiorentini, Carla ^b   Malorni, Walter ^b   Abbracchio, Maria P ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Adenosine; Apoptosis; Myogenic cells

Indexed keywords

2 CHLOROADENOSINE; 5 IODOTUBERCIDIN; ADENOSINE; HOMOCYSTEINE; S ADENOSYLHOMOCYSTEINE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; CYTOTOXICITY; HUMAN; HUMAN CELL; MYOBLAST; MYOTUBE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

2-CHLOROADENOSINE; ACETYLCYSTEINE; ADENOSINE; ADENOSINE KINASE; ANIMALS; APOPTOSIS; CELL ADHESION; CELL LINE; CYTOSKELETON; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; HOMOCYSTEINE; INTRACELLULAR FLUID; MICE; MICROFILAMENTS; MICROSCOPY, ELECTRON, SCANNING; MUSCLE, SKELETAL; REACTIVE OXYGEN SPECIES; RECEPTORS, PURINERGIC P1; THIOINOSINE; TUBERCIDIN;

EID: 0034255910     PISSN: 09608966     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-8966(00)00118-8     Document Type: Article

References (38)

1. Allen R.T., Hunter W.J., Devendra K.A. Morphological and biochemical characterization and analysis of apoptosis. J Pharmacol Toxicol Methods. 37:1997;215-228.
2. Fredholm B.B., Abbracchio M.P., Burnstock G., et al. Nomenclature and classification of purinoceptors. Pharmacol Rev. 46:1994;143-156.
3. 3 receptor. Pathophysiological significance and therapeutic implications for neurodegenerative disorders. Ann N Y Acad Sci. 825:1997;11-22.
4. Jacobson K.A., Hoffmann C., Cattabeni F., Abbracchio M.P. Adenosine-induced cell death: evidence for receptor-mediated signalling. Apoptosis. 4:1999;197-211.
5. Wakade T.D., Palmer K.C., McCauley R., Przywara D.A., Wakade A.R. Adenosine-induced apoptosis in chick embryonic sympathethic neurons: a new physiological role for adenosine. J Physiol. 488:1995;123-128.
6. Cohen A., Hirschhorn R., Horowitz S.D., et al. Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency. Proc Natl Acad Sci USA. 75:1978;472-476.
7. Rufini S., Rainaldi G., Abbracchio M.P., et al. Actin cytoskeleton as a target for 2-chloro-adenosine: evidence for induction of apoptosis in C2C12 myoblastic cells. Biochem Biophys Res Commun. 238:1997;361-366.
8. Castro-Gago M., Lojo S., Novo I., del Rio R., Pena J., Rodriguez-Segade S. Effects of chronic allopurinol therapy on purine metabolism in Duchenne muscular dystrophy. Biochem Biophys Res Commun. 147:1987;152-157.
9. Camina F., Novo-Rodriguez M.I., Rodriguez-Segade S., Castro-Gago M. Purine and carnitine metabolism in muscle of patients with Duchenne muscular dystrophy. Clin Chim Acta. 243:1995;151-164.
10. Smith J., Fowkes G., Schofild P.N. Programmed cell death in dystrophic (mdx) muscle is inhibited by IGF-II. Cell Death Differ. 2:1995;243-251.
11. Vachon P.H., Loechel F., Xu H., Wewer U.M., Engvall E. Merosin and laminin in myogenesis: specific requirement for merosin in myotube stability and survival. J Cell Biol. 134:1996;1483-1497.
12. Fidzianska A., Goebel H.H., Warlo I. Acute infantile spinal muscular atrophy. Muscle apoptosis as a proposed pathogenetic mechanism. Brain. 113:1990;433-445.
13. Wang J., Walsh K. Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Science. 273:1996;359-361.
14. Bowen D.C., Gordon H., Hall Z.W. Altered glycosaminoglycan chain structure in a variant of the C2 mouse muscle cell line. J Neurochem. 66:1996;2580-2588.
15. Lang T.J., Badea T.C., Wade R., Shin M.L. Sublytic terminal complement attack of myotubes decreases the expression of mRNAs encoding muscle-specific proteins. J Neurochem. 68:1997;1581-1589.
16. Dodds E., Piper T.A., Murphy S.J., Dickson G. Cationic lipids and polymers are able to enhance adenoviral infection of cultured mouse myotubes. J Neurochem. 72:1999;2105-2112.
17. Nadal-Ginard B. Commitment, fusion and biochemical differentiation of a myogenic cell line in the absence of DNA synthesis. Cell. 15:1978;855-864.
18. Lackie J.M., Dow J.A.T. The dictionary of cell biology. 1998;Academic Press, New York.
19. Matarrese P., Giandomenico V., Fiorucci G., et al. Antiproliferative activity of interferon alpha and retinoic acid in SiHa carcinoma cells: the role of cell adhesion. Int J Cancer. 76:1998;531-540.
20. Conti L., Rainaldi G., Matarrese P., et al. The HIV-1 vpr protein acts as a negative regulator of apoptosis in a human lymphoblastoid T cell line: possible implications for the pathogenesis of AIDS. J Exp Med. 187:1998;403-413.
21. Malorni W., Indovina P., Arancia G., Meschini S., Santini M.T. Effects of cesium on in vitro myoblasts differentiation: an electron microscopic study. In Vitro Cell Dev Biol. 26:1990;399-410.
22. Ceruti S., Barbieri D., Veronese E., et al. Different pathways of apoptosis revealed by 2-chloro-adenosine and deoxy-D-ribose in mammalian astroglial cells. J Neurosci Res. 47:1997;372-383.
23. Richter C., Schweizer M., Cossarizza A., Franceschi C. Control of apoptosis by the cellular ATP level. FEBS Lett. 378:1996;107-110.
24. Malorni W., Rivabene R., Santini M.T., Donelli G. N-acetyl-cysteine inhibits apoptosis and decreases viral particles in HIV-chronically infected U937 cells. FEBS Lett. 327:1993;75-78.
25. Ueland P.M. Pharmacological and biochemical aspects of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase. Pharmacol Rev. 34:1982;223-253.
26. Chiang P.K., Gordon R.K., Tal J., et al. S-Adenosylmethionine and methylation. FASEB J. 10:1996;471-480.
27. Rounds S., Yee W.L., Dawicki D.D., Harrington E., Parks N., Cutaia M.V. Mechanism of extracellular ATP- and adenosine-induced apoptosis of cultured pulmonary artery endothelial cells. Am J Physiol. 1040:1998;379-388.
28. Neary J.T., Rathbone M.P., Cattabeni F., Abbracchio M.P., Burnstock G. Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells. Trends Neurosci. 19:1996;13-18.
29. Barbieri D., Abbracchio M.P., Salvioli S., et al. Apoptosis by 2-chloro-2′-deoxy-adenosine and 2-chloro-adenosine in human peripheral blood mononuclear cells. Neurochem Int. 32:1998;493-504.
30. Geiger J.D., Parkinson F.E., Kowaluk E.A. Regulators of endogenous adenosine levels as therapeutic agents. Jacobson K.A., Jarvis M.F. Purinergic approaches in experimental therapeutics. 1997;Wiley Liss, New York.
31. 2+-mediated mechanisms. Biochem J. 304:1994;877-885.
32. Ceruti S., Barbieri D., Malorni W., et al. Different pathways of apoptosis are activated by 2-chloro-adenosine and 2-chloro-2′deoxy-adenosine in human astrocytoma cells. Drug Dev Res. 43:1998;51.
33. Tallmann M.S., Hakimian D. Purine nucleoside analogs: emerging roles in indolent lymphoproliferative disorders. Blood. 86:1995;2463-2474.
34. Seto S., Carrera C.J., Kubota M., Wasson D.B., Carson D.A. Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to non-dividing human lymphocytes. J Clin Invest. 75:1985;377-383.
35. Liu X., Kim C.N., Yang J., Jemmerson R., Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell. 86:1996;147-157.
36. Leoni L.M., Chao Q., Cottam H.B., et al. Induction of an apoptotic program in cell-free extracts by 2-chloro-2′-deoxyadenosine-5′-triphosphate and cytochrome c. Proc Natl Acad Sci USA. 95:1998;9567-9571.
37. Bergmann S., Shatrov V., Ratter F., Schiemann S., Schulze-Osthoff K., Lehmann V. Adenosine and homocysteine together enhance TNF-mediated cytotoxicity but do not alter activation of nuclear factor-KB in L929 cells. J Immunol. 153:1994;1736-1743.
38. Castellani L., Reedy M.C., Gauzzi M.C., Provenzano C., Alema' S., Falcone G. Maintenance of differentiated state in skeletal muscle: activation of v-Src disrupts sarcomeres in quail myotubes. J Cell Biol. 130:1995;871-885.