Unique and redundant functions of SR proteins, a conserved family of splicing factors, in Caenorhabditis elegans development

Mechanisms of Development

Volumn 95, Issue 1-2, 2000, Pages 67-76

  Kawano, Taizo ^a   Fujita, Masaki ^a   Sakamoto, Hiroshi ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

Caenorhabditis elegans; Embryogenesis; Germ cell development; RNA interference; Somatic gonad; Spermatogenesis; Splicing; SR protein

Indexed keywords

ARGININE; MESSENGER RNA; RNA; RNA BINDING PROTEIN; SERINE; SR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; CELL NUCLEUS; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE ISOLATION; GENETIC CODE; GERM CELL; GONAD; METAZOON; MICROSCOPY; MORPHOLOGY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FAMILY; REPORTER GENE; RNA SPLICING; SOMATIC CELL; SPERMATOGENESIS;

ANIMALS; CAENORHABDITIS ELEGANS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; RNA SPLICING; RNA-BINDING PROTEINS;

CAENORHABDITIS ELEGANS; METAZOA;

EID: 0034235347     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(00)00339-7     Document Type: Article

References (36)

1. Birney E., Kumar S., Krainer A.R. Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors. Nucleic Acids Res. 21:1993;5803-5816.
2. Blelloch R., Kimble J. Control of organ shape by a secreted metalloprotease in the nematode Caenorhabditis elegans. Nature. 399:1999;586-590.
3. Blelloch R., Newman C., Kimble J. Control of cell migration during Caenorhabditis elegans development. Curr. Opin. Cell. Biol. 11:1999;608-613.
4. Brenner S. The genetics of Caenorhabditis elegans. Genetics. 77:1974;71-94.
5. Burd C.G., Dreyfuss G. Conserved structures and diversity of functions of RNA-binding proteins. Science. 265:1994;615-621.
6. Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 391:1998;806-811.
7. Fu X.D. Specific commitment of different pre-mRNAs to splicing by single SR proteins. Nature. 365:1993;82-85.
8. Fu X.D. The superfamily of arginine/serine-rich splicing factors. RNA. 1:1995;663-680.
9. Fu X.D., Mayeda A., Maniatis T., Krainer A.R. General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5′ and 3′ splice site selection. Proc. Natl. Acad. Sci. USA. 89:1992;11224-11228.
10. Graham P.L., Kimble J. The mog-1 gene is required for the switch from spermatogenesis to oogenesis in Caenorhabditis elegans. Genetics. 133:1993;919-931.
11. Graham P.L., Schedl T., Kimble J. More mog genes that influence the switch from spermatogenesis to oogenesis in the hermaphrodite germ line of Caenorhabditis elegans. Dev. Genet. 14:1993;471-484.
12. Hodgkin J. Genetics. Riddle D.L., Blumenthal T., Meyer B.J., Priess J.R. C. elegans. 1997;881-1048 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
13. Hodgkin J.A., Brenner S. Mutations causing transformation of sexual phenotype in the nematode Caenorhabditis elegans. Genetics. 86:1977;275-287.
14. Kim Y.J., Zuo P., Manley J.L., Baker B.S. The Drosophila RNA-binding protein RBP1 is localized to transcriptionally active sites of chromosomes and shows a functional similarity to human splicing factor ASF/SF2. Genes Dev. 6:1992;2569-2579.
15. L'Hernault S.W., Arduengo P.M. Mutation of a putative sperm membrane protein in Caenorhabditis elegans prevents sperm differentiation but not its associated meiotic divisions. J. Cell Biol. 119:1992;55-68.
16. L'Hernault S.W., Shakes D.C., Ward S. Developmental genetics of chromosome I spermatogenesis-defective mutants in the nematode Caenorhabditis elegans. Genetics. 120:1988;435-452.
17. Lynch K.W., Maniatis T. Synergistic interactions between two distinct elements of a regulated splicing enhancer. Genes Dev. 9:1995;284-293.
18. Machaca K., L'Hernault S.W. The Caenorhabditis elegans spe-5 gene is required for morphogenesis of a sperm-specific organelle and is associated with an inherent cold-sensitive phenotype. Genetics. 146:1997;567-581.
19. Manley J.L., Tacke R. SR proteins and splicing control. Genes Dev. 10:1996;1569-1579.
20. Mayeda A., Zahler A.M., Krainer A.R., Roth M.B. Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing. Proc. Natl. Acad. Sci. USA. 89:1992;1301-1304.
21. Mello C., Fire A. DNA transformation. Epstein H.F., Shakes D.C. Methods in Cell Biology. 1995;451-482 Academic Press, San Diego, CA.
22. Ramchatesingh J., Zahler A.M., Neugebauer K.M., Roth M.B., Cooper T.A. A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer. Mol. Cell. Biol. 15:1995;4898-4907.
23. Ring H.Z., Lis J.T. The SR protein B52/SRp55 is essential for Drosophila development. Mol. Cell. Biol. 14:1994;7499-7506.
24. Schedl T. Developmental genetics of the germ line. Riddle D.L., Blumenthal T., Meyer B.J., Priess J.R. C. elegans. 1997;241-269 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
25. Screaton G.R., Cáceres J.F., Mayeda A., Bell M.V., Plebanski M., Jackson D.G., Bell J.I., Krainer A.R. Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. EMBO J. 14:1995;4336-4349.
26. Staknis D., Reed R. SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex. Mol. Cell. Biol. 14:1994;7670-7682.
27. Sun Q., Mayeda A., Hampson R.K., Krainer A.R., Rottman F.M. General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer. Genes Dev. 7:1993;2598-2608.
28. Tacke R., Manley J.L. Determinants of SR protein specificity. Curr. Opin. Cell. Biol. 11:1999;358-362.
29. Wang J., Manley J.L. Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways. RNA. 1:1995;335-346.
30. Wang J., Takagaki Y., Manley J.L. Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability. Genes Dev. 10:1996;2588-2599.
31. Ward S., Argon Y., Nelson G.A. Sperm morphogenesis in wild-type and fertilization-defective mutants of Caenorhabditis elegans. J. Cell Biol. 91:1981;26-44.
32. Wu J.Y., Maniatis T. Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell. 75:1993;1061-1070.
33. Zahler A.M., Lane W.S., Stolk J.A., Roth M.B. SR proteins: a conserved family of pre-mRNA splicing factors. Genes Dev. 6:1992;837-847.
34. Zahler A.M., Neugebauer K.M., Lane W.S., Roth M.B. Distinct functions of SR proteins in alternative pre-mRNA splicing. Science. 260:1993;219-222.
35. Zorio D.A., Cheng N.N., Blumenthal T., Spieth J. Operons as a common form of chromosomal organization in C. elegans. Nature. 372:1994;270-272.
36. Zhang B., Gallegos M., Puoti A., Durkin E., Fields S., Kimble J., Wickens M.P. A conserved RNA-binding protein that regulates sexual fates in the C. elegans hermaphrodite germ line. Nature. 390:1997;477-484.