Intracellular Ca2+ dynamics during spontaneous and evoked activity of leech heart interneurons: Low-threshold Ca currents and graded synaptic transmission

Journal of Neuroscience

Volumn 20, Issue 13, 2000, Pages 4930-4943

  Ivanov, Andrei I ^a   Calabrese, Ronald L ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

Ca currents; Ca Orange; Graded synaptic transmission; Intracellular Ca2+; Leech heart interneurons; Spatial and temporal pattern of changes in intracellular Ca2+

Indexed keywords

CALCIUM CHANNEL; CADMIUM; CALCIUM; TETRYLAMMONIUM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; EVOKED RESPONSE; FLUORESCENCE; HEART; INTERNEURON; ION CURRENT; LEECH; MEMBRANE CONDUCTANCE; MEMBRANE POTENTIAL; NERVE CELL NETWORK; NEUROTRANSMITTER RELEASE; NONHUMAN; OSCILLATORY POTENTIAL; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; ANIMAL; DRUG EFFECT; ELECTROSTIMULATION; GANGLION; IN VITRO STUDY; INNERVATION; KINETICS; PATCH CLAMP; PHYSIOLOGY;

ANIMALS; CADMIUM; CALCIUM; CALCIUM CHANNELS; ELECTRIC STIMULATION; EVOKED POTENTIALS; GANGLIA, INVERTEBRATE; HEART; INTERNEURONS; KINETICS; LEECHES; PATCH-CLAMP TECHNIQUES; SYNAPTIC TRANSMISSION; TETRAETHYLAMMONIUM;

EID: 0034214880     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-13-04930.2000     Document Type: Article

References (43)

1. Allbritton N L, Meyer T, Stryer L (1992) Range of messenger action of calcium ion and inositol 1,4,5-trisphosphatc. Science 258:1812-1815,
2. Angstadt JD, Calahrese RL (1991) Calcium currents and graded synaptic transmission between heart interncurons of the leech. J Neurosci 11:746-759,
3. Arhas EA, Calabresc RL (1987) Ionic conductances underlying the activity of interncurons that control heartbeat in the medicinal leech. J Neurosci 7:3945-3952,
4. Augustine GJ, Adler EM, Charlton M P (1991) The calcium signal for transmitter secretion from presynaptic nerve terminals. Ann NY Acad Sci 635:365-381,
5. Augustine GJ, Adler EM, Charlton MP, Hans M, Swandulla D, Zipser K (1992) Presynaptic calcium signals during ncurotransmitter release: detection with fluorescent indicators and other calcium ehelators. J Physiol (Paris) 86:129-134,
6. Bascai BJ, Wallen P, Lev-Ram V, Grillner S, Tsicn RY (1995) Activity-related calcium dynamics in lamprey motoneurons as revealed by video-rate confocal microscopy. Neuron 14:19-28,
7. Berridgc MJ (1997) Elementary and global aspects of calcium signalling. J Physiol (Lond) 499:291-306,
8. Berridgc MJ (1998) Neuronal calcium signalling. Neuron 21:13-26,
9. Callewaert G, Eilers J, Konnerth A (1996) Axonal calcium entry during fast "sodium" action potentials in rat ccrebellar Purkinje neurones. J Physiol (Lond) 495:641-647,
10. 2+ influx into identified leech neurones. Brain Res 746:285-293,
11. Eberhard M, Erne P (1991) Calcium binding to fluorescent calcium indicators: Calcium Green, Calcium Orange and Calcium Crimson. Biochem Biophys Res Commun 180:209-215,
12. Eilcrs J, Plant T, Konnerth A (1996) Localized calcium signalling and neuronal integration in cerebellar Purkinje neurones. Cell Calcium 20:215-226,
13. Eilcrs J, Callewaert G, Armstrong C, Konnerth A (1995) Calcium signal-ling in a narrow somatic submembrane shell during synaptic activity in cerehcllar Purkinje neurons. Proc Natl Acad Sci USA 92:10272-10276,
14. Fetcho JR, O'Malley DM (1997) Imaging neuronal networks in behaving animals. Curr Opin Ncurobiol 7:832-838,
15. Fetcho JR, Cox KJA, O'Malley DM (1998) Monitoring activity in neuronal populations with single-cell resolution in a behaving vertebrate. HistochemJ 30:153-167,
16. Ghosh A, Greenberg ME (1995) Calcium signalling in neurons: molecular mechanisms and cellular consequences. Science 268:239-247,
17. Haugland RP (1996) Handbook of fluorescent probes and research chemicals, Ed 6. Eugene, OR: Molecular Probes,
18. Heimchen F, Svoboda K, Denk W, Tank DW (1999) In vivo dendritic calcium dynamics in deep layer cortical pyramidal neurons. Nat Neurosci 2:989-996,
19. 2+ transients in hippocampal brain slices during simultaneous current- and voltage-clamp recording. Microsc Res Tech 29:279-289,
20. Katz B, Miledi R (1968) The role of calcium in ncuromuscular facilitation. J Physiol (Lond) 195:481-492,
21. Katz B, Miledi R (1970) Further study of the role of calcium in synaptic transmission. J Physiol (Lond) 207:789-801,
22. Krieger P, Büschgcs A, El Manira A (1999) Calcium channels involved in synaptic transmission from reticulospinal axons in lamprey. J Neurophysiol 81:1699-1705,
23. Lev-Ram V, Miyakawa H, Lasser-Ross N, Ross W (1992) Calcium transients in cerebcllar Purkinje neurons evoked by intraccllular stimulation. J Ncurophysiol 68:1167-1177,
24. Lev-Tov A, O'Donovan MJ (1995) Calcium imaging of motoncuron activity in the en-bloc spinal cord preparation of the neonatal rat. J Neurophysiol 74:1324-1334,
25. Llinás R, Sugimori M, Silver RB (1992) Microdomains of high calcium concentration in a prcsynaptic terminal. Science 256:677-679,
26. 2+ channels in sympathetic neurons. Neuron 1:355-365,
27. Lu J, Dalton IV JF, Stokes DR, Calabrcsc RL (1997) Functional role of Ca~' currents in graded and spike-mediated synaptie transmission between leech heart interneurons. J Neurophysiol 77:1779-1794,
28. Mainen Z, Malinow R, Svoboda K (1999) Synaptic calcium transients in single spines indicate that NMDA receptors arc not saturated. Nature 399:151-155,
29. McClellan AD, McPhcrson D, O'Donovan MJ (1994) Combined retrograde labeling and calcium imaging in spinal cord and brainstem neurons of the lamprey. Brain Res 663:61-68,
30. McPherson D, McClellan AD, O'Donovan MJ (1997) Optical imaging of neuronal activity in tissue labeled hy retrograde transport of Calcium Green Dcxtran. Brain Res Brain Res Protoc 1:157-164,
31. Nichols JG, Baylor DA ( 1968) Specific modalities and receptive fields of sensory neurons in the central nervous system of the leech. J Ncurophysiol 31:740-756,
32. Nohmi M, Hua S-Y, Kuba K (1992) Intracellular calcium dynamics in response to action potentials in bullfrog sympathetic ganglion cells. J Physiol (Lond) 458:171-190,
33. Olsen ØH, Calabrese RL (1996) Activation of intrinsic and synaptic currents in leech heart interneurons by realistic waveforms. J Neurosci 16:4958-4970,
34. Regehr WG, Tank DW (1990) Postsynaptic NMDA receptor-mediated calcium accumulation in hippocampal CA1 pyramidal cell dendritcs. Nature 345:807-810,
35. Rcgchr WG, Tank DW (1994) Dendritic calcium dynamics. Curr Opin Neurobiol 4:373-382,
36. Regehr WG, Connor JA, Tank DW ( 1989) Optical imaging of calcium accumulation in hippocampal pyramidal cells during synaptic activation. Nature 341:533-536,
37. Richardson CM, Dowdall MJ, Green AC, Bowman D (1995) Novel pharmacological sensitivity of the prcsynaptic calcium channels controlling acctylcholinc release in skate electric organ. J Neurochcm 64:944-947,
38. Rohitaillc R, E Adler EM, Charlton M P (1990) Strategic Location of Calcium Channels at transmitter release sites of frog neuromuscular synapses. Neuron 5:773-779,
39. Ross WN, Graubard K (1989) Spatially and temporally resolved calcium concentration changes in oscillating neurons of crab stomatogastric ganglion. Proc Nail Acad Sci USA 86:1679-1683,
40. 2+ and K' currents. Proc Natl Acad Sci USA 77:629-633,
41. Shibuya I, Douglas W W (1992) Calcium channels in rat melanotrophs are permeable to manganese, coball, cadmium, and lantanium, but not to nickel: evidence provided by fluorescence changes in Fura-2 loaded cells. Endocrinology 131:1936-1941,
42. Tolbert LP, Calabrese RL (1985) Anatomical analysis of contacts between identified neurons that control heartbeat in the leech Hirudo mi-dicinalis. Cell Tissue Res 242:257-267,
43. Zucker RS (1989) Short-term synaptic plasticity. Annu Rev Neurosci 12:13-31,