Retinoic acid receptor and retinoid X receptor alterations in lung cancer precursor lesions

Cancer Research

Volumn 60, Issue 11, 2000, Pages 2869-2875

  Martinet, Nadine ^a   Alla, François ^b   Farré, Guillaume ^a   Labib, Taonfika ^a   Drouot, Hèlène ^a   Vidili, Reynald ^a   Picard, Evelyne ^a   Gaube, Marie Pierre ^c   Le Faou, Danielle ^a   Siat, Joëlle ^a   Borelly, Jacques ^a   Vermylen, Phillippe ^d   Bazarbachi, Taha ^a   Vignaud, Jean Michel ^a   Martinet, Yves ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

^b Service d'Epidemiologie   (France)

^c UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^d Oncology Jules Bordet Center   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR;

ARTICLE; CANCER SURGERY; CIGARETTE SMOKING; CLINICAL ARTICLE; CONTROLLED STUDY; GENE LOCUS; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG CANCER; LUNG SURGERY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

ALLELES; BRONCHI; CARCINOMA IN SITU; EPITHELIUM; FEMALE; GENOTYPE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MESOTHELIOMA; MICROSATELLITE REPEATS; PRECANCEROUS CONDITIONS; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; SMOKING; TRANSCRIPTION FACTORS;

EID: 0034214209     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Sundaresan, V., Ganly, P., Hasleton, P., Rudd, R., Sinha, G., and Bleehen, N. M. P53 and chromosome 3 abnormalities, characteristic of malignant lung tumors, are detectable in preinvasive lesions of the bronchus. Oncogene, 7: 1989-1997, 1992.
2. Klein, N., Vignaud, J. M., Sadmi, M., Plenat, F., Borelly, J., Duprez, A., Martinet, Y., and Martinet, N. Squamous metaplasia expression of proto-oncogenes and P53 in lung cancer patients. Lab. Invest., 68: 26-32, 1993.
3. Hammond, W. G., Teplitz, R. L., and Benfield, J. R. Variable regression of experimental bronchial preneoplasia during carcinogenesis. J. Thorac. Cardiovasc. Surg., 101: 800-806, 1991.
4. Martinet, Y., Brambilla, E., Martin, J. P., Martinet, N., and Vignaud, J. M. Les bases biologiques de la prévention du cancer du poumon. Médecine Sciences, 13: 1465-1471, 1997.
5. Mao, L., Lee, J. S., Kurie, J. M., Fan, Y. H., Lippman, S. M., Lee, J. J., Ro, J. Y., Broxson, A., Yu, R., Morice, R. C., Kemp, B. L., Khuri, F. R., Walsh, G. L., Hittelmann, W. N., and Hong, W. F. Clonal genetic alterations in the lungs of current and former smokers. J. Natl. Cancer Inst., 89: 857-862, 1997.
6. Wistuba, I.I., Lam, S., Behrens, C., Virmani, A. K., Fong, K. M., LeRiche, J., Samet, J. M., Srivastava, S , Minna, J. D., and Gazdar, A. F. Molecular damage in the bronchial epithelium of current and former smokers. J. Natl. Cancer Inst., 89: 1366-1373, 1997.
7. Auerbach, O., Hammond, E. C., and Garfinkel, L. Changes in bronchial epithelium in relation to smoking and cancer of the lung. N. Engl. J. Med., 265: 253-267, 1961.
8. Going, J. J., and Laub, R. F. Practical histological microdissection for PCR analysis. J. Pathol., 179: 121-124, 1979.
9. Kishimoto, Y., Sugio, K., Hung, J. Y., Virmani, A. K., McIntre, D. D., Minna, J. D., and Gazdar, F. Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small-cell lung cancers. J. Natl. Cancer Inst., 87: 1224-1291, 1995.
10. Gazdar, A. F., Bader, S., Hung, J., Kishimoto, Y., Sekido, Y., and Sugio, K. Molecular genetic changes found in human lung cancer and its precursor lesions. Cold Spring Harbor Symp. Quant. Biol., 59: 565-572, 1994.
11. Thiberville, L., Payne, P., Vielkinds, J., Leriche, J., Horsman, D., Nouvel, G., Palcic, B., and Lam, S. Evidence of cumulative gene losses with progression of premalignant epithelial lesions to carcinoma of the bronchus. Cancer Res., 55: 5133-5139, 1995.
12. Jetten, A. M. Retinoids, growth factors and the tracheobronchial epithelium. Lab. Invest., 59: 1-4, 1988.
13. Chambon, P. A decade of molecular biology of retinoic acid receptors. FASEB J., 10: 940-954, 1996.
14. Lee, J. S., Lippman, S. M., Benner, S. E., Lee, J. J., Ro, J. Y., Lukeman, J. M., Morice, R. C., Peters, E. J., Pang, A. C., and Pritsche, H. A., Jr. Randomized placebo controlled trial of isotretinoin in chemoprevention of bronchial squamous metaplasia. J. Clin. Oncol., 12: 937-945, 1994.
15. The α-Tocopherol, β-Carotene Cancer Prevention Study Group. The effect of vitamin E and β carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med., 330: 1029-1035, 1996.
16. Houle, B., Leduc, F., and Bradlevy, W. E. Implication of RARβ in epidermoid squamous lung cancer. Genes Chromosomes Cancer, 3: 358-366, 1991.
17. Xc, X. U., Sozzi, G., Lee, J. S., Lee, J. J., Pastorino, U., Pilotti, S., Kurie, J. M., Hong, W. K., and Lotan, R. Suppression of RARβ in NSCLC in vivo: implications for lung cancer development. J. Natl. Cancer Inst., 89: 624-629, 1997.
18. Picard, E., Seguin, C., Monhoven, N., Rochette-Egly, C., Siat, J., Borelly, J., Martinet, Y., Martinet, N., and Vignaud, J. M. Expression of retinoid receptors genes and proteins in non-small-cell lung cancer. J. Natl. Cancer Inst., 91: 59-66, 1999.
19. Virmani, A. K., Fong, K. M., Kodagoda, D., McIntire, D., Hung, J., Tonk, V., Minna, J. D., and Gazdar, A. F. Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types. Genes Chromosomes Cancer, 21: 308-319, 1998.
20. Lawrence, J. A., Merino, M. J., Simpson, J. F., Manrow, R. E., Page, D. L., and Steeg, P. S. A high-risk lesion for invasive breast cancer, ductal carcinoma in situ, exhibits frequent overexpression of retinoid X receptor. Cancer Epidemiol. Biomark. Prev., 7: 29-35, 1998.
21. Wang, Z., Boudjelal, M., Kang, S., and Voorhees, J. J., and Fisher, G. J. Ultraviolet irradiation of human skin causes functional vitamin A deficiency, preventable by all-trans retinoic acid pre-treatment. Nat. Med., 5: 418-422, 1999.
22. Miozzo, M., Sozzi, G., Musso, K., Pilotti, S., Incarbone, M., Pastorino, U., and Pierotti, M. A. Microsatellite alterations in bronchial and sputum specimens of lung cancer patients. Cancer Res., 56: 2285-2288, 1996.
23. Pylkkänen, L., Karjalainen, A., Antilla, S., Vainio, H., and Husgafvel-Pursiainen, K. No evidence of microsatellite instability but frequent loss of heterozygosity in primary resected lung cancer. Environ. Mol. Mutagen., 30: 217-223, 1997.
24. Lerebours, F., Olschwang, S., Thuille, B., Schmitz, A., Fouchet, P., Buecher, B., Martinet, N., Galateau, F., and Thomas, G. Fine deletion mapping of chromosome 8p in non-small-cell lung carcinoma. Int. J. Cancer, 81: 854-858, 1999.
25. Wiest, J. S., Franklin, W. A., Drabkin, H., Gemmill, R., Sidransky, D., and Anderson, M. W. Genetic markers for early detection of lung cancer and outcome measures for response to chemoprevention. J. Cell Biochem., 28/29: 64-73, 1997.
26. Fong, K. M., Biesterveld, E. J., Virmani, A., Wistuba, I., Sekido, Y., Bader, S. A., Ahmadian, M., Ong, S. T., Rassool, F. V., Zimmerman, P. V., Giaccone, G., Gazdar, A. F., and Minna, J. D. FHIT and FRA3B 3p14.2 allele losses are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations. Cancer Res., 57: 2256-2267, 1997.
27. Todd, S., Franklin, W. A., Varella-Garcia, M., Kennedy, T., Hilliker, C. E., Jr., Hahner, L., Anderson, M., Wiest, J. S., Drabkin, H. A., and Gemmill, R. M. Homozygous deletions of human chromosome 3p in lung tumors. Cancer Res., 57: 1344-1352, 1997.
28. Killary, A. M., Wolf, M. E., Giambermardi, T. A., and Naylor, S. L. Definition of a tumor suppressor locus within human chromosome 3p21-p22. Proc. Natl. Acad. Sci. USA, 89: 1721-1729, 1992.
29. Bennett, W. P., Colby, T. V., Travis, W. D., Borkowski, A., Jones, R. T., Lane, D. P., Metcalf, R. A., Samet, J. M., Takeshima, Y., Gu, J. R., Vähäkangas, K. H., Soini, Y., Pääkkǎ, P., Welsh, J. A., Trump, B. F., and Harris, C. C. P53 protein accumulates frequently in early bronchial neoplasia. Cancer Res., 53: 4817-4822, 1993.
30. Sozzi, G., Miozzo, M., Donghi, R., Pilotti, S., Cariani, C. T., Pastorino, U., Della Porta, G., and Pierotti, M. A. Deletions of 17p and p53 mutations in preneoplastic lesions of the lung. Cancer Res., 52: 6079-6082, 1992.
31. Colby, V. Precursor lesions to pulmonary neoplasia. In: C. Brambilla and E. Brambilla (eds.), Lung Tumor, pp. 61-87. New York: M. Dekker, 1999.
32. Fisseler-Eckhoff, A., Erfkamp, S., and Muller, K. M. Cytokeratin expression in preneoplastic lesions and early squamous cell carcinoma of the bronchi. Pathol. Res. Pract., 192: 552-559, 1996.
33. Zhou, J., Mulshine, J. L., Unsworth, E. J., Scott, F. M., Avis, I. M., Vos, M. D., and Treston, A. M. Purification and characterization of a protein that permits early detection of lung cancer. J. Biol. Chem., 271: 10760-10766, 1996.