Glutamate and γ-aminobutyric acid content and release of synaptosomes from temporal lobe epilepsy patients

Journal of Neuroscience Research

Volumn 60, Issue 5, 2000, Pages 686-695

  Hoogland, G ^a   Hens, J J H ^a   De Wit, M ^a   Van Veelen, C W M ^b   Van Huffelen, A C ^b   Gispen, W H ^a   De Graan, P N E ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Calcium; GABA; Glutamate; Synaptosomes; Temporal lobe epilepsy (TLE)

Indexed keywords

4 AMINOBUTYRIC ACID; CALCIUM; GLUTAMIC ACID;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CALCIUM CELL LEVEL; HUMAN; HUMAN TISSUE; NONHUMAN; PRIORITY JOURNAL; TEMPORAL LOBE EPILEPSY;

EID: 0034214090     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(20000601)60:5<686::AID-JNR14>3.0.CO;2-P     Document Type: Article

References (59)

1. Aas JE, Berg-Johnsen J, Hegstad E, Laake JH, Langmoen IA, Ottersen OP. 1993. Redistribution of glutamate and glutamine in slices of human neocortex exposed to combined hypoxia and glucose deprivation in vitro. J Cereb Blood Flow Metab 13:503-515.
2. Aird RB, Masland RL, Woodbury DM. 1984. The epilepsies, a critical review. New York: Raven Press.
3. Babb TL, Brown WJ. 1986. Neuronal, dendritic, and vascular profiles of human temporal lobe epilepsy correlated with cellular physiology in vivo. Adv Neurol 44:949-966.
4. Babb TL, Pretorius JK, Kupfer WR, Crandall PH. 1989. Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus. J Neurosci 9:2562-2574.
5. Bekenstein JW, Lothman EW. 1993. Dormancy of inhibitory interneurons in a model of temporal lobe epilepsy. Science 259:97-100.
6. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
7. Carlson H, Ronne Engstrom E, Ungerstedt U, Hillered L. 1992. Seizure related elevations of extracellular amino acids in human focal epilepsy. Neurosci Lett 140:30-32, 1992.
8. Debets RM, van Veelen CW, van Huffelen AC, van Emde Boas W. 1991. Presurgical evaluation of patients with intractable partial epilepsy: the Dutch epilepsy surgery program. Acta Neurol Belgium 91:125-140.
9. Do KQ, Klancnik JM, Gahwiler B, Perschak H, Wieser HG, Cuenod M. 1991. Release of excitatory aminoacids: animal studies and epileptic foci studies in humans. In: Meldrum BS, Moroni F, Simon RP, Woods JH, editors. Excitatory amino acids. New York: Raven Press. p 677-685.
10. Dunkley PR, Heath JW, Harrison SM, Jarvie PE, Glenfield PJ, Rostas JA. 1988. A rapid Percoll gradient procedure for isolation of synaptosomes directly from an S1 fraction: homogeneity and morphology of subcellular fractions. Brain Res 441:59-71.
11. During MJ, Spencer DD. 1993. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet 341:1607-1610.
12. During MJ, Ryder KM, Spencer DD. 1995. Hippocampal GABA transporter function in temporal-lobe epilepsy. Nature 376:174-177.
13. Engel J Jr. 1992. Experimental animal models of epilepsy: classification and relevance to human epileptic phenomena. Epilepsy Res Suppl 8:9-20.
14. +-evoked release of L-glutamate in entorhinal kindled rats. Brain Res 442:368-372.
15. Glass M, Dragunow M. 1995. Neurochemical and morphological changes associated with human epilepsy. Brain Res Brain Res Rev 21:29-41.
16. Griffin WS, Yeralan O, Sheng JG, Boop FA, Mrak RE, Rovnaghi CR, Burnett BA, Feoktistova A, Van Eldik LJ. 1995. Overexpression of the neurotrophic cytokine S100 beta in human temporal lobe epilepsy. J Neurochem 65:228-233.
17. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
18. Hamberger A, Nystrom B, Silfvenius H. 1992. Extra- and intracellular amino acids in the CNS of patients with epilepsy and other neurological disorders. Epilepsy Res Suppl 8:375-381.
19. Haugstad TS, Hegstad E, Langmoen IA. 1992. Calcium dependent release of gamma-aminobutyric acid (GABA) from human cerebral cortex. Neurosci Lett 141:61-64.
20. Hegstad E, Haugstad TS, Hauglie Haussen E, Langmoen IA. 1992. Calcium-dependent release of glutamate from human cerebral cortex. Brain Res 585:340-342.
21. Heinemann U, Konnerth A, Pumain R, Wadman WJ. 1986. Extracellular calcium and potassium concentration changes in chronic epileptic brain tissue. Adv Neurol 44:641-661.
22. Heizmann CW, Braun K. 1992. Changes in Ca(2+)-binding proteins in human neurodegenerative disorders. Trends Neurosci 15:259-264.
23. Hoogland G, Blomenrohr M, Dijstelbloem H, de Wit M, Spierenburg HA, van Veelen CW, van Rijen PC, van Huffelen AC, Gispen WH, de Graan PN. 1999. Characterization of neocortical and hippocampal synaptosomes from temporal lobe epilepsy patients. Brain Res 837:55-66.
24. Johansen FF. 1993. Interneurons in rat hippocampus after cerebral ischemia. Morphometric, functional, and therapeutic investigations. Acta Neurol Scand Suppl 150:1-32.
25. Kamphuis W, Huisman E, Wadman WJ, Heizmann CW, Lopes da Silva FH. 1989. Kindling induced changes in parvalbumin immunoreactivity in rat hippocampus and its relation to long-term decrease in GABA-immunoreactivity. Brain Res 479:23-34.
26. Kamphuis W, Huisman E, Dreijer AM, Ghijsen WE, Verhage M, Lopes da Silva FH. 1990. Kindling increases the K(+)-evoked Ca2(+)-dependent release of endogenous GABA in area CA1 of rat hippocampus. Brain Res 511:63-70.
27. Kaura S, Bradford HF, Young AM, Croucher MJ, Hughes PD. 1995. Effect of amygdaloid kindling on the content and release of amino acids from the amygdaloid complex: in vivo and in vitro studies. J Neurochem 65:1240-1249.
28. Kay AR, Wong RK. 1986. Isolation of neurons suitable for patch-clamping from adult mammalian central nervous systems. J Neurosci Methods 16:227-238.
29. Liebowitz NR, Pedley TA, Cutler RW. 1977. Release of gamma-aminobutyric acid from hippocampal slices of the rat following generalized seizures induced by daily electrical stimulation of entorhinal cortex. Brain Res 138:369-373.
30. Lleu PL, Labiner D, Weinand M, Huxtable RJ. 1994. Neuroactive amino acids in synaptosomes from focal and nonfocal temporal lobe tissue of patients with intractable complex partial seizures. Adv Exp Med Biol 359:435-443.
31. Mattson MP, Rychlik B, Chu C, Christakos S. 1991. Evidence for calcium-reducing and excito-protective roles for the calcium-binding protein calbindin-D28k in cultured hippocampal neurons. Neuron 6:41-51.
32. Meldrum BS. 1986. Cell damage in epilepsy and the role of calcium in cytotoxicity. Adv Neurol 44:849-855.
33. Meldrum BS. 1991. Excitotoxicity and epileptic brain damage. Epilepsy Res 10:55-61.
34. Meldrum BS. 1995. Neurotransmission in epilepsy. Epilepsia 36:S30-S35.
35. Miller HP, Levey AI, Rothstein JD, Tzingounis AV, Conn PJ. 1997. Alterations in glutamate transporter protein levels in kindling-induced epilepsy. J Neurochem 68:1564-1570.
36. Mody I, Otis TS, Staley KJ, Kohr G. 1992. The balance between excitation and inhibition in dentate granule cells and its role in epilepsy. Epilepsy Res Suppl 9:331-339.
37. Nagy AK, Houser CR, Delgado Escueta AV. 1990. Synaptosomal ATPase activities in temporal cortex and hippocampal formation of humans with focal epilepsy. Brain Res 529:192-201.
38. Nicholls DG, Sihra TS. 1986. Synaptosomes possess an exocytotic pool of glutamate. Nature 321:772-773.
39. Perry TL, Hansen S. 1981. Amino acid abnormalities in epileptogenic foci. Neurology 31:872-876.
40. Petroff OA, Pleban LA, Spencer DD. 1995. Symbiosis between in vivo and in vitro NMR spectroscopy: the creatine, N-acetylaspartate, glutamate, and GABA content of the epileptic human brain. Magn Reson Imaging 13:1197-1211.
41. Pollen DA, Trachtenberg MC. 1970. Neuroglia: gliosis and focal epilepsy. Science 167:1252-1253.
42. Ronne Engstrom E, Hillered L, Flink R, Spannare B, Ungerstedt U, Carlson H. 1992. Intracerebral microdialysis of extracellular amino acids in the human epileptic focus. J Cereb Blood Flow Metab 12:873-876.
43. Rothstein JD, Dykes Hoberg M, Pardo CA, Bristol LA, Jin L, Kunel RW, Kanai Y, Hediger MA, Wang Y, Schielke JP, Welty DF. 1996. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 16:675-686.
44. Sarantis M, Attwell D. 1990. Glutamate uptake in mammalian retinal glia is voltage- and potassium-dependent. Brain Res 516:322-325.
45. Sayer RJ, Brown AM, Schwindt PC, Crill WE. 1993. Calcium currents in accutely isolated human neocortical neurons. J Neurophysiol 69:1596-1606.
46. Sherwin AL, Van Gelder NM. 1986. Amino acid and catecholamine markers of metabolic abnormalities in human focal epilepsy. Adv Neurol 44:1011-1032.
47. Sherwin A, Quesney F, Gauthier S, Olivier A, Robitaille Y, McQuaid P, Harvey C, van Gelder N. 1984. Enzyme changes in actively spiking areas of human epileptic cerebral cortex. Neurology 34:927-933.
48. Sherwin A, Robitaille Y, Quesney F, Olivier A, Villemure J, Leblanc R, Feindel W, Andermann E, Gotman J, Andermann F, et al. 1988. Excitatory amino acids are elevated in human epileptic cerebral cortex. Neurology 38:920-923.
49. Sloviter RS. 1991. Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: the "dormant basket cell" hypothesis and its possible relevance to temporal lobe epilepsy. Hippocampus 1:41-66.
50. Sloviter RS, Sollas AL, Barbaro NM, Laxer KD. 1991. Calcium-binding protein (calbindin-D28K) and parvalbumin immunocytochemistry in the normal and epileptic human hippocampus. J Comp Neurol 308:381-396.
51. Swanson TH. 1995. The pathophysiology of human mesial temporal lobe epilepsy. J Clin Neurophysiol 12:2-22.
52. Szatkowski M, Barbour B, Attwell D. 1990. Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake. Nature 348:443-446.
53. Tanaka K, Watase K, Manabe T, Yamada K, Watanabe M, Takahashi K, Iwama H, Nishikawa T, Ichihara N, Kikuchi T, Okuyama S, Kawashima N, Hori S, Takimoto M, Wada K. 1997. Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science 276:1699-1702.
54. Van Gelder NM, Sherwin AL, Rasmussen T. 1972. Amino acid content of epileptogenic human brain: focal versus surrounding regions. Brain Res 40:385-393.
55. 2+ homeostasis and synaptosomal preparation. J Neurochem 51:1667-1674.
56. 2+-dependent regulation of presynaptic stimulus-secretion coupling. J Neurochem 53:1188-1194.
57. 2+-dependent transmitter release. Progr Neurobiol 42:539-574.
58. Wilson CL, Maidment NT, Shomer MH, Behnke EJ, Ackerson L, Fried I, Engel J. 1996. Comparison of seizure related amino acid release in human epileptic hippocampus versus a chronic, kainate rat model of hippocampal epilepsy. Epilepsy Res 26:245-254.
59. Wyler AR, Dohan FC, Schweitzer JB, Berry AD. 1992. A grading system for mesial temporal pathology (hippocampal sclerosis) from anterior temporal lobectomy. J Epilepsy 5:220-225.