Ionic mechanism of electroresponsiveness in cerebellar granule cells implicates the action of a persistent sodium current

Journal of Neurophysiology

Volumn 80, Issue 2, 1998, Pages 493-503

  D'Angelo, Egidio ^a   De Filippi, Giovanna ^a   Rossi, Paola ^a   Taglietti, Vanni ^a  

^a Istituto di Fisiologia Generale   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOPYRIDINE; OMEGA CONOTOXIN GVIA; TETRYLAMMONIUM;

ACTION POTENTIAL; AFTERHYPERPOLARIZATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CALCIUM CURRENT; CELL MEMBRANE DEPOLARIZATION; CEREBELLUM; GRANULAR CELL; MEMBRANE CURRENT; MOSSY FIBER; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SODIUM CURRENT; SPIKE;

EID: 0031812614     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1998.80.2.493     Document Type: Article

References (45)

1. +-dependent theta-like rhythmicity in stellate cells of entorhinal cortex layer II. Nature 342: 175-177, 1989.
2. ALTMAN, J. Postnatal development of the cerebellar cortex in the rat. III. Maturation of the components of the granular layer. J. Comp. Neurol. 145: 465-514, 1972.
3. + current in pyramidal neurons from rat and cat sensorimotor cortex. J. Neurosci. 13: 660-673, 1993.
4. Azouz, R., JENSEN, M. S., AND YAARI, Y. Ionic basis of spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells. J. Physiol. (Lond.) 492: 211-223, 1996.
5. BARDONI, R. AND BELLUZZI, O. Kinetic study and numerical reconstruction of A-type current in granule cells of rat cerebellar slices. J. Neurophysiol. 69: 2222-2231, 1993.
6. + channels of small conductance in cultured rat skeletal muscle. Nature 323: 718-720, 1986.
7. A receptors. J. Physiol. (Lond.) 497: 753-759, 1996.
8. CONNORS, B. W. AND GUTNICK, M. J. Intrinsic firing patterns of diverse neocortical neurons. Trends Neurosci. 13: 99-104, 1990.
9. CONNOR, J. A. AND STEVENS, C. F. Predictions of repetitive firing behaviour from voltage-clamp data on an isolated neuron soma. J. Physiol. (Lond.) 213: 31-53, 1971.
10. CULL-CANDY, S. G., MARSHALL, C. G., AND OGDEN, D. Voltage-activated membrane currents in rat cerebellar granule neurones. J. Physiol. (Lond.) 414: 179-199, 1989.
11. D'ANGELO, E., DE FILIPPI, G., ROSSI, P., AND TAGLIETTI, V. Synaptic excitation of individual rat cerebellar granule cells in situ: evidence for the role of NMDA receptors. J. Physiol. (Lond.) 484: 397-413, 1995.
12. 2+ action potentials in immature rat cerebellar granule cells in situ. J. Neurophysiol. 78: 1631-1642, 1997.
13. D'ANGELO, E., ROSSI, P., DE FILIPPI, G., MAGISTRETTI, J., AND TAGLIETTI, V. The relationship between synaptogenesis and expression of voltage-dependent currents in cerebellar granule cells in situ. J. Physiol. Paris 88: 197-207, 1994.
14. D'ANGELO, E., ROSSI, P., AND TAGLIETTI, V. Different proportions of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor currents at the mossy fibre-granule cell synapse of developing rat cerebellum. Neuroscience 53: 121-130, 1993.
15. EDWARDS, F. A., KONNERTH, A., SAKMANN, B., AND TAKAHASHI, T. A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Pflügers Arch. 414: 600-612, 1989.
16. + channel by stimulation of glutamate phosphoinositide-coupled receptors in cultured cerebellar granule cells. Eur. J. Neurosci. 3: 778-789, 1991.
17. FRIEDMAN, A. AND GUTNICK, M. J. Intracellular calcium and control of burst generation in neurons of guinea-pig neocortex in vitro. Eur. J. Neurosci. 1: 374-381, 1989.
18. GABBIANI, F., MIDTGAARD, J., AND KNOEPFEL, T. Synaptic integration in a model of cerebellar granule cells. J. Neurophysiol. 72: 999-1009, 1994.
19. GUTFREUND, Y., YAROM, Y., AND SEGEV, I. Subthreshold oscillations and resonant frequency in guinea-pig cortical neurons: physiology and modelling. J. Physiol. (Lond.) 483: 621-640, 1995.
20. HOCHMAN, S., JORDAN, L. M., AND MACDONALD, J. F. N-methyl-D-aspartate receptor-mediated voltage oscillations in neurons surrounding the central canal in slices of rat spinal cord. J. Neurophysiol 72: 565-577, 1994.
21. HOCKBERGER, P. E., TSENG, H.-Y., AND CONNOR, J. A. Immunocytochemical and electrophysiological differentiation of rat cerebellar granule cells in explant cultures. J. Neurosci. 7: 1370-1383, 1987.
22. HORN, D. AND MARTY, A. Muscarinic activation of ionic currents measured by a new whole-cell recording method. J. Gen. Physiol. 92: 145-159, 1988.
23. ITO, M. Granule Cells. In: The Cerebellum and Neuronal Control. New York: Raven, 1984, p. 74-93.
24. + channel and rescue of weaver granule cells. Neuron 16: 941-952, 1996.
25. + channels amplify EPSPs in hippocampal CA1 pyramidal cells. J. Neurophysiol. 76: 2181-2191, 1996.
26. LLINAS, R. R. The intrinsic electrophysiological properties of mammalian central neurons: insights into central nervous system function. Science 242: 1654-1664, 1988.
27. MAGISTRETTI, J., MANTEGAZZA, M., GUATTEO, E., AND WANKE, E. Action potentials recorded with patch-clamp amplifiers: are they genuine? Trends Neurosci. 19: 530-534, 1996.
28. MAINEN, Z. F. AND SEJNOWSKI, T. J. Influence of dendritic structure on firing pattern in model neocortical neurons. Nature 382: 363-366, 1996.
29. MARCHETTI, C., AMICO, C., AND USAI, C. Functional characterization of the effect of nimodipine on the calcium current in rat cerebellar granule cells. J. Neurophysiol. 73: 1169-1180, 1995.
30. MCCORMICK, D. A., CONNORS, B. W., LIGHTHALL, J. W., AND PRINCE, D. A. Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex. J. Neurophysiol. 54: 782-806, 1985.
31. MCCORMICK, D. A, HUGUENARD, J., AND STROWBRIDGE, B. W. Determinant of state-dependent processing in thalamus by single neuron properties and neuromodulators. In: Single Neuron Computation, edited by T. McKenna, J. Davis, and S. F. Zornetzer. London, UK: Academic, 1992, p. 259-290.
32. + channels from mammalian skeletal muscle. Nature 313: 316-318, 1985.
33. 2+ channel currents in rat cerebellar granule cells. J. Neurosci. 15: 2995-3012, 1995.
34. ROSSI, P., D'ANGELO, E., MAGISTRETTI, J., TOSELLI, M., AND TAGLIETTI, V. Age-dependent expression of high-voltage activated calcium currents during cerebellar granule cell development in situ. Pflügers Arch. 429: 107-116, 1994.
35. RUDY, B. Diversity and ubiquity of K channels. Neuroscience 25: 729-749, 1988.
36. SCHWINDT, P. C. Ionic currents governing input-output relations of Betz cells. In: Single Neuron Computation, edited by T. McKenna, J. Davis, and S. F. Zornetzer. London, UK: Academic, 1992, p. 235-258.
37. SCHWINDT, P., O'BRIEN, J. A., AND CRILL, W. Quantitative analysis of firing properties of pyramidal neurons from layer 5 of rat sensorimotor cortex. J. Neurophysiol. 77: 2484-2498, 1997.
38. SILVA, L. R., AMITAI, Y., AND CONNORS, B. W. Intrinsic oscillations of neocortex generated by layer 5 pyramidal neurons. Science 251: 432-435, 1991.
39. SILVER, R. A., TRAYNELIS, S. F., AND CULL-CANDY, S. G. Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ. Nature 355: 163-166, 1992.
40. SIMON, S. M. AND LLINAS, R. R. Compartmentalization of the submembrane calcium activity during calcium influx and its significance in transmitter release. Biophys. J. 48: 485-498, 1985.
41. STEWART, R. R., Bossu, J.-L., MUZET, M., DUPONT, J.-L., AND FELTZ, A. Voltage-activated ionic currents in differentiating rat cerebellar granule neurons cultured from the external germinal layer. J. Neurobiol. 28: 419-432, 1995.
42. STORM, J. F. Potassium currents in hippocampal pyramidal cells. Prog. Brain Res. 83: 161-187, 1990.
43. + current in cerebellar granule cells. Proc. Natl. Acad. Sci. USA 93: 11191-11195, 1996.
44. + currents that fail to inactivate. Trends Neurosci. 16: 455-460, 1993.
45. + current sensitive to muscarinic receptor activation in rat cultured cerebellar granule neurons. J. Physiol. (Lond.) 491: 401-412, 1996.