Effect of mitogens on growth and contractile responses of rat small arteries: In vitro studies

Acta Physiologica Scandinavica

Volumn 169, Issue 2, 2000, Pages 103-113

  Schiotz L M ^a   Buus, C L ^a   Hessellund, A ^a   Mulvany, M J ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Angiotensin; Organ culture; Platelet derived growth factor; Proliferation; Protein synthesis; Rat; Remodelling; Resistance artery

Indexed keywords

ACETYLCHOLINE; ANGIOTENSIN II; ANTICOAGULANT AGENT; BRADYKININ; DIAGNOSTIC AGENT; DNA; MITOGENIC AGENT; PHENYLEPHRINE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB; THYMIDINE; TRITIUM; VASOCONSTRICTOR AGENT; VASODILATOR AGENT;

ANIMAL; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL DIVISION; CYTOLOGY; DRUG EFFECT; IN VITRO STUDY; MALE; MESENTERIC ARTERY; METABOLISM; NICK END LABELING; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; RAT; VASCULAR RESISTANCE; VASOCONSTRICTION; WISTAR RAT;

ACETYLCHOLINE; ANGIOTENSIN II; ANIMALS; ANTICOAGULANTS; APOPTOSIS; BRADYKININ; CELL DIVISION; DNA; IN SITU NICK-END LABELING; MALE; MESENTERIC ARTERIES; MITOGENS; ORGAN CULTURE TECHNIQUES; PHENYLEPHRINE; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, WISTAR; THYMIDINE; TRITIUM; VASCULAR RESISTANCE; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS;

EID: 0034203959     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201x.2000.00726.x     Document Type: Article

References (49)

1. Allen, S.P., Liang, H.M., Hill, M.A. & Prewitt, R.L. 1996. Elevated pressure stimulates protooncogene expression in isolated mesenteric arteries. Am J Pbjsiol 21\, H1517-HI 523.
2. Araki, S., Kawahara, Y., Kariya, K. et al. 1990. Stimulation of platelet-derived growth factor-induced DNA synthesis by angiotensin II in rabbit vascular smooth muscle cells. Biochem Biopbjs Res Commun 168, 350-357.
3. Bardy, N., Merval, R., Benessiano, J., Samuel, J.L. & Tedgui, A. 1996. Pressure and angiotensin II synergistically induce aortic fibronectin expression in organ culture model of rabbit aorta. Evidence for a pressure-induced tissue reninangiotensin system. Ore Res 79, 70-78.
4. Berk, B.C. & Corson, M.A. 1997. Angiotensin II signal transduction in vascular smooth muscle: Role of tyrosine kinases. Cm Res 80, 607-616.
5. Birukov, K.G., Lehoux, S., Birukova, A.A., Merval, R., Tkachuk, V.A. & Tedgui, A. 1997. Increased pressure induces sustained protein kinase C-independent herbimycin A-sensitive activadon of extracellular signal-related kinase 1/2 in the rabbit aorta in organ culture. Circ Res 81, 895-903.
6. Buus, C.L., Schiotz, L.M. & Mulvany, M.J. 1999. Growth and contractile responses of cultured resistance arteries (Abstract). Hypertension 34, 698.
7. De Mey, J.G.R., Uitendaal, M.P., Boonen, H.C.M., Vrijdag, M.J.J.F., Daemen, MJ.A.P. & Struyker-Boudier, H.A.J. 1989. Acute and long-term effects of tissue culture on contractile reactivity in renal arteries of the rat. Circ Res 65, 1125-1135.
8. De Mey, J.G.R., Uitendaal, M.P., Boonen, H.C., Schiffers, P.M. & Fazzi, G.E. 1991. Growth responses in isolated elastic, muscular and resistance-sized arterial segments of the rat. Blood Vessels 28, 372-385.
9. Fenger Gron, J., Mulvany, MJ. & Christensen, K.L. 1997. Intestinal blood flow is controlled by both feed arteries and microcirculatory resistance vessels in freely moving rats. J Plysiol Loud 498, 215-224.
10. Folkow, B. 1982. Physiological aspects of primary hypertension. Phjsiol Rev 62, 347-504.
11. Geisterfer, A.A.T., Peach, MJ. & Owens, G.K. 1988. Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells. Circ Res 62, 749-756.
12. Griendling, K.K., Lassegue, B. & Alexander, RAX'. 1996. Angiotensin receptors and their therapeutic implications. Annti Rev Pharmacol Toxicol 36, 281-306.
13. Griffin, S.A., Brown, W.C., Macpherson, F. et al. 1991. Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanism. Hypertension 17, 626-635.
14. Hafizi, S., Nobin, R., Allen, S.P., Chester, A.H. & Yacoub, M.H. 1998. Contrasting effects of platelet-derived growth factor (PDGF) isomers on mitogenesis, contraction and intracellular calcium concentration in human vascular smooth muscle. Acta Plysiol Scand 164, 191-199.
15. Holt, C.M., Francis, S.E., Gadsdon, P.A., Violaris, A., Izzat, M.B. & Angelini, G.D. 1994. Release of platelet derived growth factor in serum-free organ culture of human coronary artery. Cardioiasc Res 28, 1170-1175.
16. Holycross, B.J., Peach, MJ. & Owens, G.K. 1993. Angiotensin II stimulates increased protein synthesis, not increased DNA synthesis, in intact rat aortic segments, in vitro. J Vasc Res 30, 80-86.
17. 2+ in rabbit isolated ear artery by platelet-derived growth factor. BrJ Pbarmacol 114, 138-142.
18. Hughes, A.D., Clunn, G.F., Refson, J. & Demoliou Mason, C. 1996. Platelet-derived growth factor (PDGF): Actions and mechanisms in vascular smooth muscle. Gen Pbarr/iacol 27, 1079-1089.
19. Ishibashi, K. & Bukoski, R.D. 1997. Myosin isoform expression and force generation in cultured resistance arteries. Am] Pbjsiol 272, C1144-C1150.
20. Kolpakov, V., Rekhter, M.D., Gordon, D., Wang, W.H. & Kulik, TJ. 1995. Effect of mechanical forces on growth and matrix protein synthesis in the in vitro pulmonary artery. Analysis of the role of individual cell types. Circ Res 77, 825-831.
21. Lehoux, S. & Tedgui, A. 1998. Signal transduction of mechanical stresses in the vascular wall. Hypertension 32, 338-345.
22. Lindqvist, A., Nilsson, B.O. & Hellstrand, P. 1997. Inhibition of calcium entry preserves contractility of arterial smooth muscle in culture. J Vasc Res 34, 103-108.
23. Linseman, D.A., Benjamin, C.W. & Jonesf D.A. 1995. Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells. J Bio! Cbem 210, 12563-12568.
24. Merrick, A.F., Shewring, L.D., Cunningham, S.A., Gustafsson, K. & Fabre, J.W. 1997. Organ culture of arteries for experimental studies of vascular endothelium in situ. Transpl Imatanol 5, 3-9.
25. Aliriel, V.A., Alien, S.V., Schriver, S.D. & Prewitt, R.L. 1999. Genistein inhibits pressure-induced expression of f-fos in isolated mesenteric arteries. Hypertension 34, 132-137.
26. Mitsumata, M., Fishel, R.S., Nerem, R.M., Alexander, R.W. & Berk, B.C. 1993. Fluid shear stress stimulates plateletderived growth factor expression in endothelial cells. Am J P/ysio/265, H3-H8.
27. Mulvany, MJ., Baumbach, G.L., Aalkjcer, C. et al. 1996. Vascular remodelling (Letter to editors). Hypertension 28, 505-506.
28. Mulvany, MJ. & Halpern, W. 1977. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res 41, 19-26.
29. Mulvany, MJ. & Nyborg, N.C.B. 1980. An increased calcium sensitivity of mesenteric resistance vessels in young and adult spontaneously hypertensive rats. BrJ Phamiacol 71, 585-596.
30. Myllarniemi, M., Calderon, L., Lemstrom, K., Buchdunger, E. & Hayry, P. 1997. Inhibition of platelet-derived growth factor receptor tyrosine kinase inhibits vascular smooth muscle cell migration and prolifération. FASEB J 11, 1119-1126.
31. Owens, G.K. 1995. Regulation of differentiation of vascular smooth muscle cells. Plysiol Rev 75, 487-517.
32. Parker, S.B., Wade, S.S. & Prewitt, R.L. 1998. Pressure mediates angiotensin II-induced arterial hypertrophy and PDGF-A expression. Hypertension 32, 452-458.
33. Schieffer, B., Paxton, W.G., Marrero, M.B. & Bernstein, K.E. 1996. Importance of tyrosine phosphorylation in angiotensin II type 1 receptor signaling. Hypertension 27, 476-480.
34. Schiffers, P.M., Fazzi, G.E., van Ingen Schenau, D. & De Mey, J.G.R. 1994. Effects of candidate autocrine and paracrine mediators on growth responses in isolated rat arteries. Arterioscler Thromb 14, 420-426.
35. Sharifi, A.M. & Schiffrin, E.L. 1998. Apoptosis in vasculature of spontaneously hypertensive rats: Effect of an angiotensin converting enzyme inhibitor and a calcium channel antagonist. Am J Hypertem 11, 1108-1116.
36. Skalli, O., Schurch, W., Seemayer, T. et al. 1989. Myofibroblasts from diverse pathologic settings are heterogeneous in their content of acrin isoforms and intermediate filament proteins. Lab Invest 60, 275-285.
37. Stassen, F.R., Raat, N.J., Brouwers Geiler, D.L., Fazzi, G.E., Smits, J.F. & De Mey, J.G.R. 1997. Angiotensin II induces media hypertrophy and hyperreactivity in mesenteric but not epigastric small arteries of the rat. J Vasc Res 34, 289-297.
38. Su, E.J., Lombard), D.M., Siegal, J. & Schwanz, S.M. 1998. Angiotensin II induces vascular smooth muscle cell replication independent of blood pressure. Hypertension 31, 1331-1337.
39. Sudhir, K., Wilson, E., Chatterjee, K. & Ives, H.E. 1993. Mechanical strain and collagen potentiate mitogenic activity of angiotensin II in rat vascular smooth muscle cells. J Clin Invest 92, 3003-3007.
40. Takahashi, E. & Berk, B.C. 1998. MAP kinases and vascular smooth muscle function. Acta Pbjsiol Scand 164, 611-621.
41. Tulis, D.A. & Prewitt, R.L. 1998. Medial and endothelial platelet-derived growth factor A chain expression is regulated by in vivo exposure to elevated flow. J Vasc Res 35, 413-420.
42. Watts, S.W., Florian, J.A. & Monroe, K.M. 1998. Dissociation of angiotensin Il-stimulated activation of mitogen-acrivated protein. J Pharmacol Exp 77w286, 1431-1438.
43. Weber, H., Taylor, D.S. & Molloy, CJ. 1994. Angiotensin II induces delayed mitogenesis and cellular proliferation in rat aortic. J Clin Inrest 93, 788-798.
44. Wiener.J., Lombard!, D.M., Su, J.E. & Schwanz, S.M. 1996. Immunohistochemical and molecular characterization of the differential response of the rat mesenteric microvasculature to angiotensin-II infusion. J Vasc Res 35, 195-208.
45. Williams, B. 1998. Mechanical influences on vascular smooth muscle cell function. J Hjpertens 16, 1921-1929.
46. Wright, G., Wang, S., Bailey, G., Reichenbecher, V. & Wright, G.L. 1996. Effect of retinoic acid on contractile competence of vascular smooth muscle. AmJ Plysiol 270, H1363-H1370.
47. Yamawaki, H., Sato, K., Hori, M., Ozaki, H. & Karaki, H. 1999a. Impairment of endothelium-dependent relaxation in the arteries cultured with fetal bovine serum. EnrJ Pbarmacol 366, 237-242.
48. Yamawaki, H., Sato, K., Hori, M. et al. 1999b. Impairment of EDR by a long-term PDGF treatment in organ-cultured rabbit mesentery artery. Am J P/ysio/217, H318-H323.
49. Yang, Z., Oemar, B.S., Carrel, T., Kipfer, B., Julmy, F. & Luscher, T.F. 1998. Different proliferative properties of smooth muscle cells of human arterial and venous bypass vessels: Role of PDGF receptors, mitogen-activated protein kinase, and cyclin-dependent kinase inhibitors. Circulation 97, 181-187.