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Volumn 186, Issue 1, 2000, Pages 61-65

Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus

Author keywords

Actinomycetes; Anticancer; Antitumor; Polyketide; Streptomyces

Indexed keywords

ANTINEOPLASTIC AGENT; MITHRAMYCIN; POLYKETIDE;

EID: 0034193797     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(00)00116-6     Document Type: Article
Times cited : (19)

References (19)
  • 1
    • 0344994565 scopus 로고    scopus 로고
    • The biosynthesis of aureolic acid group antibiotics
    • Rohr J., Méndez C., Salas J.A. The biosynthesis of aureolic acid group antibiotics. Bioorg. Chem. 27:1999;41-54
    • (1999) Bioorg. Chem. , vol.27 , pp. 41-54
    • Rohr, J.1    Méndez, C.2    Salas, J.A.3
  • 2
    • 0001747786 scopus 로고    scopus 로고
    • Genetic contributions to understanding polyketide synthase
    • Hopwood D.A. Genetic contributions to understanding polyketide synthase. Chem. Rev. 97:1997;2465-2497
    • (1997) Chem. Rev. , vol.97 , pp. 2465-2497
    • Hopwood, D.A.1
  • 3
    • 0030090909 scopus 로고    scopus 로고
    • Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents
    • Blanco G., Fu H., Méndez C., Khosla C., Salas J.A. Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents. Chem. Biol. 3:1996;193-196
    • (1996) Chem. Biol. , vol.3 , pp. 193-196
    • Blanco, G.1    Fu, H.2    Méndez, C.3    Khosla, C.4    Salas, J.A.5
  • 4
    • 0029934431 scopus 로고    scopus 로고
    • Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin
    • Lombó F., Blanco G., Fernández E., Méndez C., Salas J.A. Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin. Gene. 172:1996;87-91
    • (1996) Gene , vol.172 , pp. 87-91
    • Lombó, F.1    Blanco, G.2    Fernández, E.3    Méndez, C.4    Salas, J.A.5
  • 6
    • 0031690038 scopus 로고    scopus 로고
    • Identification of two genes from Streptomyces argillaceus encoding two glycosyltransferases involved in the transfer of a disaccharide during the biosynthesis of the antitumor drug mithramycin
    • Fernández E., Weißbach U., Sánchez Reillo C., Braña A.F., Méndez C., Rohr J., Salas J.A. Identification of two genes from Streptomyces argillaceus encoding two glycosyltransferases involved in the transfer of a disaccharide during the biosynthesis of the antitumor drug mithramycin. J. Bacteriol. 180:1998;4929-4937
    • (1998) J. Bacteriol. , vol.180 , pp. 4929-4937
    • Fernández, E.1    Weißbach, U.2    Sánchez Reillo, C.3    Braña, A.F.4    Méndez, C.5    Rohr, J.6    Salas, J.A.7
  • 7
    • 0033984935 scopus 로고    scopus 로고
    • Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus
    • Blanco G., Fernández E., Fernández-Lozano M.J., Braña A.F., Weißbach U., Künzel E., Rohr J., Méndez C., Salas J.A. Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus. Mol. Gen. Genet. 262:2000;991-1000
    • (2000) Mol. Gen. Genet. , vol.262 , pp. 991-1000
    • Blanco, G.1    Fernández, E.2    Fernández-Lozano, M.J.3    Braña, A.F.4    Weißbach, U.5    Künzel, E.6    Rohr, J.7    Méndez, C.8    Salas, J.A.9
  • 9
    • 0032902411 scopus 로고    scopus 로고
    • The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster
    • Lombó F., Braña A.F., Méndez C., Salas J.A. The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster. J. Bacteriol. 181:1999;642-647
    • (1999) J. Bacteriol. , vol.181 , pp. 642-647
    • Lombó, F.1    Braña, A.F.2    Méndez, C.3    Salas, J.A.4
  • 10
    • 0029840323 scopus 로고    scopus 로고
    • An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus
    • Fernández E., Lombó F., Méndez C., Salas J.A. An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus. Mol. Gen. Genet. 251:1996;692-698
    • (1996) Mol. Gen. Genet. , vol.251 , pp. 692-698
    • Fernández, E.1    Lombó, F.2    Méndez, C.3    Salas, J.A.4
  • 12
    • 0000182975 scopus 로고
    • XL1-Blue: A high efficiency plasmid transforming recA Escherichia coli strain with beta-galactosidase selection
    • Bullock W.O., Fernández J.M., Short J.N. XL1-Blue: a high efficiency plasmid transforming recA Escherichia coli strain with beta-galactosidase selection. Biotechniques. 5:1987;376
    • (1987) Biotechniques , vol.5 , pp. 376
    • Bullock, W.O.1    Fernández, J.M.2    Short, J.N.3
  • 13
    • 0034007775 scopus 로고    scopus 로고
    • Identification and expression of genes involved in L-oleandrose biosynthesis and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus
    • in press
    • Aguirrezabalaga, I., Olano, C., Allende, N., Rodriguez, L., Braña, A.F., Méndez, C. and Salas, J.A. (2000) Identification and expression of genes involved in L-oleandrose biosynthesis and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus. Antimicrob. Agents Chemother., in press
    • (2000) Antimicrob. Agents Chemother.
    • Aguirrezabalaga, I.1    Olano, C.2    Allende, N.3    Rodriguez, L.4    Braña, A.F.5    Méndez, C.6    Salas, J.A.7
  • 14
    • 0025967413 scopus 로고
    • Plasmid cloning vectors that integrate site-specifically in Streptomyces spp.
    • Kuhstoss S., Richardson M.A., Rao N.R. Plasmid cloning vectors that integrate site-specifically in Streptomyces spp. Gene. 97:1991;143-146
    • (1991) Gene , vol.97 , pp. 143-146
    • Kuhstoss, S.1    Richardson, M.A.2    Rao, N.R.3
  • 15
    • 0022404392 scopus 로고
    • Cloning and analysis of the promoter region of the erythromycin resistance gene (ermE) of Streptomyces erythraeus
    • Bibb M.J., Janssen G.R., Ward J.M. Cloning and analysis of the promoter region of the erythromycin resistance gene (ermE) of Streptomyces erythraeus. Gene. 38:1985;215-226
    • (1985) Gene , vol.38 , pp. 215-226
    • Bibb, M.J.1    Janssen, G.R.2    Ward, J.M.3
  • 16
    • 0029950580 scopus 로고    scopus 로고
    • The Streptomyces peucetius drrC gene encodes a UvrA-like protein involved in daunorubicin resistance and production
    • Lomovskaya N., Hong S.K., Kim S.U., Fonstein L., Furuya K., Hutchinson R.C. The Streptomyces peucetius drrC gene encodes a UvrA-like protein involved in daunorubicin resistance and production. J. Bacteriol. 178:1996;3238-3245
    • (1996) J. Bacteriol. , vol.178 , pp. 3238-3245
    • Lomovskaya, N.1    Hong, S.K.2    Kim, S.U.3    Fonstein, L.4    Furuya, K.5    Hutchinson, R.C.6
  • 17
    • 0023025816 scopus 로고
    • Sequences of Escherichia coli uvrA gene and protein reveal two potential ATP binding sites
    • Hussain I., Van Houten B., Thomas D.C., Sancar A. Sequences of Escherichia coli uvrA gene and protein reveal two potential ATP binding sites. J. Biol. Chem. 261:1986;4895-4901
    • (1986) J. Biol. Chem. , vol.261 , pp. 4895-4901
    • Hussain, I.1    Van Houten, B.2    Thomas, D.C.3    Sancar, A.4
  • 18
    • 0024677088 scopus 로고
    • Micrococcus luteus homolog of the Escherichia coli uvrA gene: Identification of a mutation in the UV-sensitive mutant DB7
    • Shiota S., Nakayama H. Micrococcus luteus homolog of the Escherichia coli uvrA gene: identification of a mutation in the UV-sensitive mutant DB7. Mol. Gen. Genet. 217:1989;332-340
    • (1989) Mol. Gen. Genet. , vol.217 , pp. 332-340
    • Shiota, S.1    Nakayama, H.2
  • 19
    • 0021760092 scopus 로고
    • A comprehensive set of sequence analysis programs for the VAX
    • Devereux J., Haeberli P., Smithies O. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:1984;387-395
    • (1984) Nucleic Acids Res. , vol.12 , pp. 387-395
    • Devereux, J.1    Haeberli, P.2    Smithies, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.