Persistent activation of G(s)α through limited proteolysis by calpain

Biochemical Journal

Volumn 347, Issue 3, 2000, Pages 733-740

  Sato Kusubata, Kaori ^a   Yajima, Yukiko ^a   Kawashima, Seiichi ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Adenylate cyclase; cAMP; Cholera toxin; Pituitary adenylate cyclase activating polypeptide (PACAP); Protease

Indexed keywords

ADENYLATE CYCLASE; CALPAIN; CALPASTATIN; CHOLERA TOXIN; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; LEUPEPTIN; ADCYAP1 PROTEIN, RAT; ANTIBODY; BENZYLOXYCARBONYLLEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCINE ALDEHYDE; CYSTEINE PROTEINASE INHIBITOR; DIPEPTIDE; NEUROPEPTIDE; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LOCALIZATION; HYPOPHYSIS CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; ADENOHYPOPHYSIS; ANIMAL; CELL CULTURE; CHEMISTRY; CYTOLOGY; CYTOSOL; DOSE RESPONSE; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; IMMUNOLOGY; KINETICS; METABOLISM; MOLECULAR WEIGHT; PROTEIN PROCESSING; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; ANIMALS; ANTIBODIES; CALPAIN; CELL MEMBRANE; CHOLERA TOXIN; CYCLIC AMP; CYSTEINE PROTEINASE INHIBITORS; CYTOSOL; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; KINETICS; MOLECULAR WEIGHT; NEUROPEPTIDES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; PITUITARY GLAND, ANTERIOR; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0034192481     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3470733     Document Type: Article

References (33)

1. 1 Gilman, A. G. (1987) Annu. Rev. Biochem. 56, 615-649
2. 2 McKenzie, F R. and Milligan, G. (1990) J. Biol. Chem. 265, 17084-17093
3. 3 Mitchell, F. M., Buckley, N. J. and Milligan, G. (1993) Biochem. J. 293, 495-499
4. 4 Yajima, Y., Akita, Y., Saito, T. and Kawashima, S. (1998) J. Biochem. (Tokyo) 123, 1024-1030
5. 5 Chang, F.-H. and Bourne, H. R. (1989) J. Biol. Chem. 264, 5352-5357
6. 6 Saido, T. C., Sorimachi, H. and Suzuki, K. (1994) FASEB J. 8, 814-822
7. 7 Kishimoto, A., Mikawa, K., Hashimoto, K., Yasuda, I., Tanaka, S., Tominaga, M., Kuroda, T. and Nishizuka, Y. (1989) J. Biol. Chem. 264, 4088-4092
8. 8 Banno, Y., Nakashima, S., Hachiya, T. and Nozawa, Y. (1995) J. Biol. Chem. 270, 4318-4324
9. 9 Oda, A., Druker, B. J., Ariyoshi, H., Smith, M. and Salzman, E. W. (1993) J. Biol. Chem. 268, 12603-12608
10. 10 Cooray, P., Yuan, Y., Schoenwaeleder, S. M., Mitchell, C. A., Salem, H. H. and Jackson, S. P. (1996) Biochem. J. 318, 41-47
11. 11 Trembly, J. and Hamet, P. (1984) Metab. Clin. Exp. 33, 689-695
12. 12 Kawashima, S., Ohsumi, M., Hayashi, M., Inomata, M., Nakamura, M. and Imahori, K. (1984) J. Biochem. (Tokyo) 95, 1231-1234
13. 13 Tashjian, Jr., A. H. (1979) Methods Enzymol. 58, 527-535
14. 14 Yajima, Y., Akita, Y. and Saito, T. (1986) J. Biol. Chem. 261, 2684-2689
15. 15 Laemmli, U.K. (1970) Nature (London) 227, 680-685
16. 16 Wedegaertner, P. B., Bourne, H. R. and von Zastrow, M. (1996) Mol. Biol. Cell 7, 1225-1233
17. 17 Clapham, D. E. and Neer, E. J. (1997) Annu. Rev. Pharmacol. Toxicol. 37, 167-203
18. 18 Tsubuki, S., Saito, Y., Tomioka, M., Ito, H. and Kawashima, S. (1996) J. Biochem. (Tokyo) 119, 572-576
19. 19 Eto, A., Akita, Y., Saido, T. C., Suzuki, K. and Kawashima, S. (1995) J. Biol. Chem. 270, 25115-25120
20. 20 Paulssen, R. H., Johansen, P. W., Gordeladze, J. O., Nymoen, Ø., Paulssen, E. J. and Gautvik, K. M. (1994) Eur. J. Biochem. 222, 97-103
21. 21 Levis, M. J. and Bourne, H. R. (1992) J. Cell Biol. 119, 1297-1307
22. 22 Milligan, G. (1993) Trends Pharmacol. Sci. 14, 413-418
23. 23 Sprang, S. R. (1997) Annu. Rev. Biochem. 66, 639-678
24. 24 Itoh, H. and Gilman, A. G. (1991) J. Biol. Chem. 266, 16226-16231
25. 25 Berlot, C. H. and Bourne, H. R. (1992) Cell 68, 911-922
26. 26 Antonelli, M., Birnbaumer, L., Allende, J. E. and Olate, J. (1994) FEBS Lett. 340, 249-254
27. 27 Markby, D. W., Onrust, R. and Bourne, H. R. (1993) Science 262, 1895-1901
28. 28 Osawa, S., Heasley, L. E., Dhanasekaran, N., Gupta, S. K., Woon, C. W., Berlot, C. and Johnson, G. L. (1990) Mol. Cell. Biol. 10, 2931-2940
29. 29 Chatterjee, T. K., Eapen, A. K. and Fisher, R. A. (1997) J. Biol. Chem. 272, 15481-15487
30. 30 Banno, Y., Asano, T. and Nozawa, Y. (1994) FEBS Lett. 340, 185-188
31. 31 Rock, M. T., Brooks, W. H. and Roszman, T. L. (1997) J. Biol. Chem. 272, 33377-33383
32. 32 Choi, Y. H., Lee, S. J., Nguyen, P.-M., Jang, J. S., Lee, J. L., Wu, M.-L., Takano, E., Maki, M., Henkart, P. A. and Trepel, J. B. (1997) J. Biol. Chem. 272, 28479-28484
33. 33 Spiegel, A. M., Gierschik, P., Levine, M. A. and Downs, Jr., R. W. (1985) N. Engl. J. Med. 312, 26-33