cDNA cloning and characterization of human Δ5-desaturase involved in the biosynthesis of arachidonic acid

Biochemical Journal

Volumn 347, Issue 3, 2000, Pages 719-724

  Leonard, Amanda E ^a   Kelder, Bruce ^b   Bobik, Emil G ^a   Chuang, Lu Te ^a   Parker Barnes, Jennifer M ^a   Thurmond, Jennifer M ^a   Kroeger, Paul E ^a   Kopchick, John J ^b   Huang, Yung Sheng ^a   Mukerji, Pradip ^a  

^a ABBOTT LABORATORIES   (United States)

^b OHIO UNIVERSITY   (United States)

Author keywords

Chromosome 11; Dihomo linolenic acid (DGLA); Long chain polyunsaturated fatty acids

Indexed keywords

ACYL COENZYME A DESATURASE; ARACHIDONIC ACID; COMPLEMENTARY DNA; DEOXYRIBONUCLEASE I;

ADRENAL GLAND; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; BIOSYNTHESIS; BRAIN; CHROMOSOME 11Q; CONTROLLED STUDY; DATA BASE; DNA LIBRARY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; EXPRESSED SEQUENCE TAG; FIBROBLAST CULTURE; GENE EXPRESSION; GENE MAPPING; HUMAN; HUMAN TISSUE; LIVER; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETINA MACULA VITELLIFORM DEGENERATION; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

8,11,14-EICOSATRIENOIC ACID; AMINO ACID SEQUENCE; ANIMALS; ARACHIDONIC ACID; CHROMOSOMES, HUMAN, PAIR 11; CLONING, MOLECULAR; DATABASES, FACTUAL; DNA, COMPLEMENTARY; EXPRESSED SEQUENCE TAGS; FATTY ACID DESATURASES; FATTY ACIDS; GAMMA-LINOLENIC ACID; GENE EXPRESSION PROFILING; HUMANS; L CELLS (CELL LINE); LINOLEOYL-COA DESATURASE; MICE; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PHYSICAL CHROMOSOME MAPPING; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; TRANSFECTION;

EID: 0034192327     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3470719     Document Type: Article

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