The use of AP-PCR and flaA-RFLP typing to investigate treatment failure in Helicobacter pylori infection

Clinical Microbiology and Infection

Volumn 6, Issue 5, 2000, Pages 265-267

  Adamsson, I ^a   Edlund, C ^a,b   Seensalu, R ^c   Engstrand, L ^d  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b SÖDERTÖRN UNIVERSITY   (Sweden)

^c ST GÖRAN S HOSPITAL   (Sweden)

^d Swedish Inst Infec Dis Control   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMOXICILLIN NM PHARMA; CAGA PROTEIN; CLARITHROMYCIN; FLAGELLIN; METRONIDAZOLE; OMEPRAZOLE; VIRULENCE FACTOR;

ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL THERAPY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; DNA FINGERPRINTING; GENE EXPRESSION; GENETIC VARIABILITY; GENOTYPE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR TYPING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RECURRENT INFECTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RIBOTYPING; STOMACH BIOPSY; SWEDEN; TREATMENT FAILURE; UNIVERSITY HOSPITAL;

BACTERIA (MICROORGANISMS); HELICOBACTER; HELICOBACTER PYLORI;

EID: 0034191852     PISSN: 1198743X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1469-0691.2000.00058.x     Document Type: Article

References (20)

1. Ge Z, Taylor D. Helicobacter pylori-molecular genetics and diagnostic typing. Br Med Bul 1998; 54: 31-8.
2. Forbes KJ, Fang Z, Pennington TH. Allelic variation in the Helicobacter pylori flagellin genes flaA and flaB: its consequences for strain typing schemes and population structure. Epidemiol Infect 1995; 114: 257-66.
3. Jorgensen M, Daskalopoulos G, Warburton V, Mitchell H, Hazell S. Multiple strain colonization and metronidazole resistance in Helicobacter pylori-infected patients: identification from sequential and multiple biopsy specimens. J Infect Dis 1996; 174: 631-5.
4. Owen RJ, Bickley J, Hurtado A, Fraser A, Pounder RE. Comparison of PCR-based restriction length polymorphism analysis of urease genes with tRNA gene profiling for monitoring Helicobacter pylori infections in patients on triple therapy. J Clin Microbiol 1994; 5: 1203-10.
5. Enroth H, Nyrén O, Engstrand L. One stomach-one strain: does Helicobacter pylori strain variation influence disease outcome? Dig Dis Sci 1999; 1: 102-7.
6. Marshall D, Chua A, Keeling N, Sullivan D, Coleman D, Smyth C. Molecular analysis of Helicobacter pylori populations in antral biopsies from individual patients using randomly amplified polymorphic DNA (RAPD) fingerprint. FEMS Immunol Med Microbiol 1995; 10: 317-24.
7. Censini S, Lange C, Xiang Z et al. Cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci USA 1996; 93: 14648-53.
8. van Doorn LJ, Figueiredo C, Sanna R et al. Expanding allelic diversity of Helicobacter pylori vacA. J Clin Microbiol 1998; 36: 2597-603.
9. Takata T, Fujimoto S, Anzai K et al. Analysis of the expression of cagA and vacA and the vacuolating activity in 167 isolates from patients with either peptic ulcers or non-ulcer dyspepsia. Am J Gastroenterol 1998; 93: 30-4.
10. Adamsson I, Nord CE, Sjöstedt S, Wikström B, Seensalu R. The value of different detection methods of Helicobacter pylori during treatment. J Clin Gastroenterol 1998; 27: 138-42.
11. Tummuru MKR, Cover TL, Blaser MJ. Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production. Infect Immun 1993; 61: 1799-809.
12. Atherton JC, Cao P, Peek RM, Tummuru MKR, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. J Biol Chem 1995; 270: 17771-7.
13. Taylor N, Fox J, Akopyants S et al. Long-term colonization with single and multiple strains of Helicobacter pylori assessed by DNA fingerprinting. J Clin Microbiol 1995; 33: 918-23.
14. Dore MP, Osato MS, Know DH, Graham D, El-Zaatari FAK. Demonstration of unexpected antibiotic resistance of genotypically identical Helicobacter pylori isolates. Clin Infect Dis 1998; 27: 84-9.
15. Weel JFL, van der Hulst RWM, Gerrits Y et al. The interrelationship between cytotoxin-associated geneA, vacuolating cytotoxin, and Helicobacter pylori-related diseases. J Infect Dis 1996; 173: 1171-5.
16. Parsonette J, Friedman GD, Orentreich N, Vogelman H. Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection. Gut 1997; 40: 297-301.
17. Go MF, Graham DY. Presence of the cagA gene in the majority of Helicobacter pylori strains is independent of whether the individual has duodenal ulcer or asymptomatic gastritis. Helicobacter 1996; 1: 107-11.
18. Mitchell HM, Hazell SL, Hu PJ. Serological response to specific Helicobacter pylori antigens: antibody against CagA antigen is not predictive of gastric cancer in a developing country. Am J Gastroenterol 1996; 9: 1785-8.
19. Atherton JC, Peek RMJ, Tham KT, Cover TL, Blaser MJ. Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori. Gastroenterology 1997; 112: 92-9.
20. Rudi J, Kolb C, Maiwald M et al. Diversity of Helicobacter pylori vacA genes and relationship to VacA and CagA protein expression, cytotoxin production, and associated disease. J Clin Microbiol 1998; 36: 944-8.