Variation in sensitizing effect of caffeine in human tumour cell lines after γ-irradiation

Radiotherapy and Oncology

Volumn 54, Issue 3, 2000, Pages 261-271

  Valenzuela, Maria Teresa ^a   Mateos, Santiago ^b   Ruiz De Almodóvar, J Mariano ^a   McMillan, Trevor J ^c  

^a Laboratoio Invest Medicas y B   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

^c Inst Environ Nat Sci   (United Kingdom)

Author keywords

Caffeine; Cell cycle; p53; Radiation

Indexed keywords

CAFFEINE; PROTEIN P53;

ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL SPECIFICITY; CELL STRAIN MCF 7; CLONOGENIC ASSAY; CONTROLLED STUDY; FLOW CYTOMETRY; GAMMA IRRADIATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RADIOSENSITIZATION; TUMOR CELL LINE; VARIANCE;

BREAST NEOPLASMS; CAFFEINE; CELL CYCLE; FEMALE; G1 PHASE; G2 PHASE; GAMMA RAYS; HUMANS; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; RHABDOMYOSARCOMA; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; URINARY BLADDER NEOPLASMS;

EID: 0034161913     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-8140(99)00180-2     Document Type: Article

References (40)

1. Baker S.J., Markowitz S., Fearon E.R., Willson J.K., Vogelstein B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science. 249:1990;912-915.
2. Bhattacharjee S.B., Bhattacharyya N., Chatterjeb S. Influence of caffeine on X-ray-induced killing and mutation in V7 cells. Radiat. Res. 109:1987;310-318.
3. Bunz F., Dutnaux A., Lengauer C., et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science. 282:1998;1497-1501.
4. Crompton N.E.A., Ham J., Jaussi R., Burkart W. Staurosporine and radiation induced G2 cell cycle blocks are equally released by caffeine. Radiat. Res. 135:1993;372-379.
5. Fingert H.J., Pu A.T., Chen Z.Y., Googe P.B., Alley M.C., Pardee A.B. In vivo and in vitro enhanced antitumor effects by pentoxifylline in human cancer cells treated with thiotepa. Cancer Res. 48:1988;4375-4381.
6. Friedman H.S., Schold S.C. Jr, Varia M., Bigner D.D. Chemotherapy and radiation therapy of human medulloblastoma in athymic nude mice. Cancer Res. 43:1983;3088-3093.
7. Gilligan D., Mort C., McMillan T.J., Peacock J.H., Titley J., Ormerod M.G. Application of a bromodeoxyuridine-Hoechst/ethidium bromide technique for the analysis of radiation-induced cell cycle delays in asynchronous cell populations. Int. J. Radiat. Biol. 69:1996;251-257.
8. Ham J., Weller E.M., Jung T., Burkart W. Effects of ionizing- and UV B-radiation on proteins controlling cell cycle progression in human cells: comparison of MCF-7 adenocarcinoma and the SCL-2 squasmous cell carcinoma cell line. Int. J. Radiat. Biol. 70:1996;261-271.
9. Harris C.C. Structure and function of p53 tumor-suppressor gene: clues for rational cancer-therapeutic strategies. J. Nat. Cancer Inst. 88:1996;1442-1455.
10. Hartwell L.H., Kastan M.B. Cell cycle control and cancer. Science. 266:1994;1821-1825.
11. Iliakis G., Nusse M. Effects of caffeine on X-irradiated synchronous, asynchronous and plateau phase mouse ascites cells: the importance of progression through the cell cycle for caffeine enhancement of killing. Int. J. Radiat. Biol. Relat Stud. Phys. Chem. Med. 43:1983;649-663.
12. Kastan M.B., Canman C.E., Leonard C.J. p53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev. 14:1995;3-15.
13. Kastan M.B., Onyekwere O., Sidransky D., Vogelstein B., Craig R.W. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51:1991;6304-6311.
14. Kaufmann W.K., Paules R.S. DNA damage and cell cycle checkpoints. FASEB J. 10:1996;238-247.
15. Kelland L.R., Steel G.G. Modification of radiation dose-rate sparing effects in a human carcinoma of the cervix cell line by inhibitors of DNA repair. Int. J. Radiat. Biol. 54:1988;229-244.
16. Kim S.H., Khil M.S., Ryu S., Kim J.H. Enhancement of radiation response on human carcinoma cells in culture by pentoxifylline. Int. J. Radiat. Oncol. Biol. Phys. 25:1993;61-65.
17. Kuerbitz S.J., Plunkett B.S., Walsh W.V., Kastan M.B. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA. 89:1992;7491-7495.
18. Lau C.C., Pardee A.B. Mechanism by which caffeine potentiates lethality of nitrogen mustard. Proc. Natl. Acad. Sci. USA. 79:1982;2942-2946.
19. Leeper D.B., Schneiderman M.H., Dewey W.C. Radiation induced division delay in synchronized Chinese hamster ovary cells in monolayer culture. Radiat. Res. 50:1972;401-417.
20. Little J.B. Delayed initation of DNA synthesis in irradiated human diploid cells. Nature. 218:1968;1064-1065.
21. Martinez J., Georgoff I., Martinez J., Levine A.J. Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes Dev. 5:1991;151-159.
22. Masters J.R.W., Hepbunn P.J., Walker L., et al. Tissue culture models of transitional cell carcinoma: characterization of 22 human urothelial cell lines. Cancer Res. 4:1986;3630-3636.
23. McIlwrath A.J., Vasey P.A., Ross G.M., Brown R. Cell cycle arrests and radiosensitivity of human tumour cell lines: dependence on wild-type p53 for radiosensitivity. Cancer Res. 54:1994;3718-3722.
24. McKenna W.G., Iliakis G., Weiss M.C., Bernhard E.J., Muschel R.J. Increased G2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes H-ras and v-myc. Radiat Res. 125:1991;283-287.
25. Murnane J.P. Cell cycle regulation in response to DNA damage in mammalian cells: a historical perspective. Cancer Metastasis Rev. 14:1995;17-29.
26. Musk S.R. Resuction of radiation-induced cell cycle blocks by caffeine does not necessarily lead to increased cell killing. Radiat. Res. 125:1991;262-266.
27. Musk S.R., Steel G.G. Override of the radiation-induced mitotic block in human tumor cells by methylxantines and its relationship to the potentiation of cytotoxicity. Int. J. Radiat. Biol. 57:1990;1105-1112.
28. Painter R.B., Roberston J.S. Effect of irradiation and theory of role of mitotic delay on the time course of labelling of HeLa S3 cells with tritiated thymidine. Radiat. Res. 11:1959;206-217.
29. Poot M., Ormerod M.G. Ormerod M.G. Analysis of cell proliferation by the bromodeoxyuridine Hoechst/ethiduium bromide. Flow cytometry. A practical approach. 2nd ed :1994;157-167 IRL Press at Oxford University Press, UK.
30. Powell S.N., Defrank J.S., Connel P., et al. Differential sensitivity of p53(-) and p53(+) cells to caffeine-induced radiosensitization and override of G2 delay. Cancer Res. 55:1995;1643-1648.
31. Ribeiro J.C., Barnetson A.R., Fisher R.J., Mameghan H., Russell P.J. Relationship between radiation response and p53 status in human bladder cancer cells. Int. J. Radiat. Biol. 72:1997;11-20.
32. Russell K.J., Wiens L.W., Demers G.W., Galloway D.A., Plon S.E., Groudine M. Abrogation of the G2 checkpoint results in differential radiosensitization of G1 checkpoint-deficient and G1 checkpoint-competent cells. Cancer Res. 55:1995;1639-1642.
33. Siles E., Villalobos M., Jones L., et al. Apoptosis after gamma irradiation. Is it an important cell death modality? Br. J. Cancer. 78:1998;1600-1606.
34. Siles E., Villalobos M., Valenzuela M.T., et al. Relationship between p53 status and radiosensitivity in human tumor cell lines. Br. J. Cancer. 73:1996;581-588.
35. Soule H.D., Vazquez A., Long A., Albert S., Brennan M.A. Human cell lines from a pleural effusion derived from a breast carcinoma. J. Natl. Cancer Inst. 51:1973;1409-1413.
36. Stewart N., Hicks G.G., Paraskevas F., Mowat M. Evidence for a second cell cycle block at G2/M by p53. Oncogene. 10:1995;109-115.
37. Su L.-N., Little J.B. Prolonged cell cycle delay in radioresistant human cell lines transfected with activated ras oncogene and/or simian virus 40T-antigen. Radiat. Res. 133:1993;73-79.
38. Teicher B.A., Holden S.A., Herman T.S., Epelbaum R., Pardee A.B., Dezube B. Efficacy of pentoxifylline as a modulator of alkylating agent activity in vitro and in vivo. Anticancer Res. 11:1991;1555-1560.
39. Walters R., Gurley L.R., Tobey R.A. Effects of caffeine on radiation induced phenomena associated with cell cycle traverse of mammalian cells. Biophys. J. 14:1974;99-118.
40. Wolloch E.H., Sevin B.U., Perras J.P., et al. Cell kinetic perturbations after irradiation and caffeine in the BG-1 ovarian carcinoma cell line. Gynecol. Oncol. 43:1991;29-36.