Activation of extracellular signal-regulated protein kinases is associated with a sensitized locomotor response to D2 dopamine receptor stimulation in unilateral 6-hydroxydopamine-lesioned rats

Journal of Neuroscience

Volumn 20, Issue 5, 2000, Pages 1849-1857

  Cai, Guoping ^a   Zhen, Xuechu ^a   Uryu, Kunihiro ^a   Friedman, Eitan ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Dopamine receptor; ERK pathway; Locomotion; Phosphorylation; Striatum; Supersensitivity

Indexed keywords

DOPAMINE 2 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; OXIDOPAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVATION; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MALE; NERVE CELL PLASTICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR SENSITIVITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 0034161438     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-05-01849.2000     Document Type: Article

References (64)

1. Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltie AR (1995) PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinasc kinase in vitro and in vivo. J Biol Chem 270:27489-27494.
2. Arnt J, Hyttel J (1984) Differential inhibition by dopamine D-1 and D-2 antagonists of circling behavior induced by dopamine agonists in rats with unilateral 6-hydroxydopamine lesions. Eur J Pharmacol 102:349-354.
3. Atkins CM, Selcher JC, Petraitis JJ, Trzaskos JM, Sweatt JD (1998) The MAPK cascade is required for mammalian associative learning. Nat Neurosci 1:602-609.
4. Berhow MT, Hiroi N, Nestler EJ (1996) Regulation of ERK (extracellular signal regulated kinase), part of the neurotrophin signal transduction cascade, in the rat mesolimbic dopamine system by chronic exposure to morphine or cocaine. J Neurosci 16:4707-4715.
5. Blumer KJ, Johnson GL (1994) Diversity in function and regulation of MAP kinase pathways. Trends Biol Sci 19:236-240.
6. Bogoyevitch MA, Andersson MB, Gillespie-Brown J, Clerk A, Glennon PE, Fuller SJ, Sugden PH (1996) Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy. Biochem J 314:115-121.
7. Boulton TG, Yaneopoulos GD, Gergory JS, Slavughter C, Moomaw C, Hsu J, Cobb MH (1990) An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control. Science 249:64-67.
8. Boulton TG, Nye SH, Robbins DJ, Ip NY, Radziejewska E, Morgenbesser SD, DePinho RA, Panayotatos N, Cobb MH Yancopoulos GD (1991) ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 65:663-675.
9. Brambilla R, Gnesutta N, Minichiello L, White G, Roylance AJ, Herron CE, Ramsey M, Wolfer DP, Cestari V, Rossi-Arnaud C, Grant SG, Chapman PF, Sturani E, Klein R (1997) A role for the Ras signaling pathway in synaptic transmission and long-term memory. Nature 390:281-286.
10. Butkerait P, Wang HY and Friedman E (1994) Increase in guanine nucleotide binding to striatal G proteins is associated with dopamine receptor supersensitivity. J Pharmacol Exp Ther 271:422-428.
11. 1 dopamine receptor/G protein coupling in unilateral 6-hydroxydopamine-lesioned rats. Soc Neurosci Abstr 24:859.
12. 1A receptor is sensitive not only to inhibitors of phosphatidylinositol 3-kinase, but to an inhibitor of phosphatidylinositol hydrolysis. J Biol Chem 271:22297-22300.
13. Creese I, Burt DR, Snyder SH (1977) Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity. Science 197:596-598.
14. Crespo P, Xu N, Simonds WF, Gutkind JS (1994) Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits. Nature 369:418-420.
15. Crespo P, Cachero TG, Xu N, Gutkind JS (1995) Dual effect of β-adrenergic receptors on mitogen-activated protein kinase. Evidence for a βγ-dependent activation and a Gαs-cAMP-mediated inhibition. J Biol Chem 270:25259-25265.
16. Crow T, Xue-Bian JJ, Siddiqi V, Rang Y, Neary JT (1998) Phosphorylation of mitogen-activated protein kinase by one-trial and multi-trial classical conditioning. J Neurosci 18:3480-3487.
17. Della Rocca GJ, van Biesen T, Daaka Y, Luttrell DK, Luttrell LM, Lefkowitz RJ (1997) Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2 and Src Kinase. J Biol Chem 272:19125-19132.
18. English JD, Sweatt JD (1996) Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation. J Biol Chem 271:24329-24332.
19. English JD, Sweatt JD (1997) A requirement for the mitogen-activated protein kinase in hippocampal long term potentiation. J Biol Chem 272:19103-19106.
20. Faure M, Voyno-Yasenstskaya TA, Bourne HR (1994) cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells. J Biol Chem 269:7851-7854.
21. Fiorc RS, Bayer VE, Pelech SL, Posada J, Cooper JA, Baraban JM (1993) p42 mitogen-activated protein kinase in brain: prominent localization in neuronal cell bodies and dendrites. Neuroscience 55:463-472.
22. ras independent pathway. J Biol Chem 270:3491-3494.
23. 1A receptor via a G protein βγ-subunit-initiated pathway. Biochemistry 35:13716-13722.
24. Gerfen CR (1995) Dopamine receptor function in the basal ganglia. Clin Neuropharmacol 18:5162-5177.
25. Gizang-Ginsberg E, Ziff EB (1990) Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-Fos. Genes Dev 4:477-491.
26. Glennon PE, Kaddoura S, Sale EM, Sale GJ, Fuller SJ, Sugden PH (1996) Depiction of mitogen-activated protein kinase using an anti-sense oligodeoxynucleotide approach downregulates the phenyl-ephrine-induced hypertrophic response in rat cardiac myocytes. Circ Res 78:954-961.
27. Hanford DS, Glembotski CC (1996) Stabilization of B-type natriuretic peptide mRNA in cardiac myocytes by alpha-adrenergic receptor activation: potential roles for protein kinase C and mitogen-activated protein kinase. Mol Endocrinol 10:1719-1727.
28. Haycock JW, Ahn NG, Cobb MH, Krebs EG (1992) ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. Proc Natl Acad Sci USA 89:2365-2369.
29. 1 receptor stimulation. J Neurosci 10:2318-2329.
30. 1 adrenergic receptors activate phosphatidylinositol 3-kinase in human vascular smooth muscle cells. J Biol Chem 271:8977-8982.
31. Impey S, Obrietan K, Wong ST, Poser S, Yano S, Wayman G, Deloulme JC, Chan G, Storm DR (1998) Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation. Neuron 21:869-883.
32. Kitai ST (1981) Anatomy and physiology of the neostriatum. Adv Biochem Psycopharmacol 30:1-21.
33. Koch WJ, Hawes BE, Allen LF, Lefkowitz RJ (1994) Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras. Proc Natl Acad Sci USA 91:12706-12710.
34. 2 dopamine receptor stimulation of mitogenesis in transfected Chinese hamster ovary cells: relationship to dopamine stimulation of tyrosine phosphorylations. J Pharmacol Exp Ther 267:1573-1581.
35. Lewis SE, Rao MS, Symes AJ, Daurer WT, Fink JS, Landis SC, Hyman SE (1994) Coordinated regulation of choline acetyltransferase, tyrosine hydroxylase, and neuropeptide mRNAs by ciliary neurotrophic factor and leukemia inhibitory factor in cultured sympathetic neurons. J Neurochem 63:429-438.
36. Luttrell LM, Della Rocca GJ, van Biesen T, Luttrell DK, Lefkowitz RJ (1997) Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated ras activation. J Biol Chem 272:4637-4644.
37. Marcotte ER, Sullivan RM, Mishra RK (1994) Striatal G-proteins: effects of unilateral 6-hydroxydopamine lesions. Neurosci Lett 169:195-198.
38. Martin KC, Michael D, Rose JC, Barad M, Casadio A, Zhu H, Kandel ER (1997) MAP kinase translocated into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia. Neuron 18:899-912.
39. 2 dopamine receptors as a function of aging and chronic rcserpine treatment following irreversible modification: a key to receptor regulatory mechanisms. J Neurosci 7:1484-1491.
40. Oh JD, Dotto PD, Chase TN (1997) Protein kinase A inhibitor attenuates levodopa-induced motor response alterations in hemiparkinsonian rat. Neurosci Lett 228:5-8.
41. Pace AM, Faure M, Bourne HR (1995) Gi2-mediated activation of the MAP kinase cascade. Mol Biol Cell 6:1685-1695.
42. Pende M, Fisher TL, Simpson PB, Russell JT, Blenis J, Gallo V (1997) Neurotransmitter- and growth factor-induced cAMP response element binding protein phosphorylation in glial cell progenitors: role of calcium ions, protein kinase C, and mitogen-activated protein kinase/ ribosomal S6 kinase pathway. J Neurosci 17:1291-1301.
43. 2 dopamine receptors. J Neurochcm 62:411-420.
44. Rabinovsky ED, Ramchatesingh J, McManaman JL (1995) Regulation of tyrosine hydroxylase gene expression in IMR-32 neuroblastoma cells by basic fibroblast growth factor and ciliary neurotrophic factor. J Neurochcm 64:2401-2412.
45. 1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy. J Biol Chem 272:14057-14061.
46. Robinson MJ, Cobb MH (1997) Mitogen-activated protein kinase pathways. Curr Opin Cell Biol 9:180-186.
47. 2 dopamine receptors in response to a prolonged reserpine treatment in mice. J Pharmacol Exp Ther 252:810-816.
48. Sale EM, Atkinson PGP and Sale GJ (1995) Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DMA synthesis. EMBO J 14:674-684.
49. 2 dopamine receptors is restricted to the ventro- and dorsolateral regions of the striatum. Neurosci Lett 74:180-186.
50. Schlessinger J, Ullrich A (1992) Growth factor signaling by receptor tyrosine kinases. Neuron 9:383-391.
51. Seger R, Kerbs E (1995) The MAPK signaling cascade. FASEB J 9:726-735.
52. Silva AJ, Frankland PW, Marowitz Z, Friedman E, Lazlo G, Cioffi D, Jacks T, Bourtchuladze R (1997) A mouse model for the learning and memory deficits associated with neurolibromatosis type I. Nat Genet 15:281-284.
53. Skoulakis EM, Davis RL (1996) Olfactory learning deficits in mutants for leonardo, a Drosophila gene. 17:931-944.
54. Sokoloff P, Schwartz JC (1995) Novel dopamine receptors half a decade later. Trends Pharmacol Sci 16:270-275.
55. Takahashi T, Kawahara Y, Okuda M, Ueno H, Takeshita A, Yokoyama M (1997) Angiotensin II stimulates mitogen-activated protein kinases and protein synthesis by a Ras-independent pathway in vascular smooth muscle cells. J Biol Chem 272:16018-16022.
56. Touhara K, Hawes BE, van Biesen T, Lefkowitz RJ (1995) G protein βγ subunits stimulate phosphorylation of Shc adaptor protein. Proc Natl Acad Sci USA 92:9284-9287.
57. van Biesen T, Hawes BE, Luttrell DK, Krueger KM, Touhara K, Porfiri E, Sakauc M, Luttrell LM, Lefkowitz RJ (1995) Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signaling pathway. Nature 376:781-784.
58. Wan Y, Kurosaki T, Huang XY (1996) Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors. Nature 380:541-544.
59. Xing M, Insel PA (1996) Protein kinase C-dependent activation of cytosolic phospholipase A2 and mitogen-activated protein kinase by alpha 1-adrenergic receptors in Madin-Darby canine kidney cells. J Clin Invest 97:1302-1310.
60. Yan Y, Chi PP, Bourne HR (1997) RGS4 inhibits Gq-mediated activation of mitogen-activated protein kinase and phosphoinositide synthesis. J Biol Chem 272:11924-11927.
61. 1-like receptor stimulation inhibits hypertrophy induced by platelet-derived growth factor in cultured rat renal vascular smooth muscle cells. Hypertension 29:350-355.
62. Yu SM, Tsai SY, Guh JH, Ko FN, Teng CM, Ou JT (1996) Mechanism of catecholamine-induced proliferation of vascular smooth muscle cells. Circulation 94:547-554.
63. 1-dopamine receptor agonists mediate activation of p38 MAPK and JNK by a PKA-dependent mechanism in SK-N-MC human neuroblastoma cells. Mol Pharmacol 54:453-458.
64. 4 dopamine receptors (DAR) requires Src, SHC-Grb2 via Gi protein. Soc Neurosci Abstr 24:859.