Effect of chloroquine and leupeptin on intracellular accumulation of amyloid-beta (Aβ) 1-42 peptide in a murine N9 microglial cell line

FEBS Letters

Volumn 436, Issue 3, 1998, Pages 439-444

  Chu, Teresa ^a   Tran, Thuy ^a   Yang, Fusheng ^a   Beech, Walter ^b   Cole, Greg M ^a,b,c   Frautschy, Sally A ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

A4 amyloid; Alzheimer's disease; Chloroquine; Leupeptin; Lysosome; Microglia

Indexed keywords

AMYLOID BETA PROTEIN; CHLOROQUINE; FUCOIDIN; LEUPEPTIN; SCAVENGER RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL LINE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VITRO STUDY; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

AMYLOID BETA-PROTEIN; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELLS, CULTURED; CHLOROQUINE; KINETICS; LEUPEPTINS; MEMBRANE PROTEINS; MICE; MICROGLIA; PEPTIDE FRAGMENTS; POLYSACCHARIDES; RATS; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LIPOPROTEIN; RECEPTORS, SCAVENGER; SCAVENGER RECEPTORS, CLASS B;

EID: 0031785364     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)01161-2     Document Type: Article

References (36)

1. Scheuner, D., Eckman, C., Jensen, M., Song, X., Citron, M., Suzuki, N., Bird, T.D., Hardy, J., Hutton, M., Kukull, W., Larson, E., Levy-Lahad, E., Viitanen, M., Peskind, E., Poorkaj, P., Schellenberg, G., Tanzi, R., Wasco, W., Lannfelt, L., Selkoe, D. and Younkin, S. (1996) Nature Med. 2, 864-870.
2. Mullan, M., Houlden, H., Windelspecht, M., Fidani, L., Lombardi, C., Diaz, P., Rossor, M., Crook, R., Hardy, J., Duff, K. and Crawford, F. (1992) Nature Genet. 2, 340-342.
3. Haass, C. and Selkoe, D.J. (1993) Cell 75, 1039-1042.
4. Shoji, M., Golde, T.E., Ghiso, J., Cheung, T.T., Estus, S., Shaffer, L.M., Cai, X.D., McKay, D.M., Tintner, R., Frangione, B. and Younkin, S.G. (1992) Science 258, 126-129.
5. Seubert, P., Vigo-Pelfrey, C., Esch, F., Lee, M., Dovey, H., Davis, D., Sinha, S., Schlossmacher, M., Whaley, J., Swindlehurst, C., McCormack, R., Wolfert, R., Selkoe, D., Lieberburg, I. and Schenk, D. (1992) Nature 359, 325-327.
6. Burdick, D., Kosmoski, J., Knauer, M.F. and Glabe, C.G. (1997) Brain Res. 746, 275-284.
7. Ida, N., Masters, C.L. and Beyreuther, K. (1996) FEBS Lett. 394, 174-178.
8. Itagaki, S., McGeer, P.L., Akiyama, H., Zhu, S. and Selkoe, D. (1989) J. Neuroimmunol. 24, 173-182.
9. Shaffer, L.M., Dority, M.D., Gupta-Bansal, R., Frederickson, R.C.A., Younkin, S.G. and Brunden, K.R. (1995) Neurobiol. Aging 16, 737-745.
10. Mentlein, R., Ludwig, R. and Martensen, I. (1998) J. Neurochem. 70, 721-726.
11. Ard, M.D., Cole, G.M., Wei, J., Mehrle, A.P. and Fratkin, J.D. (1996) J. Neurosci. Res. 43, 190-202.
12. Paresce, D.M., Ghosh, R.N. and Maxfield, F.R. (1996) Neuron 17, 553-565.
13. Cole, G.M., Huynh, T.V. and Saitoh, T. (1989) Neurochem. Res. 14, 933-939.
14. Haass, C., Koo, E., Mellon, A., Hung, A.Y. and Selkoe, D.J. (1992) Nature 357, 500-503.
15. Golde, T.E., Estrus, S., Younkin, H.Y., Selkoe, D.J. and Younkin, S.G. (1992) Science 255, 728-730.
16. Cataldo, A.M. and Nixon, R.A. (1990) Proc. Natl. Acad. Sci. USA 87, 3861-3865.
17. Cataldo, A.M., Barnett, J.L., Mann, D.M. and Nixon, R.A. (1996) J. Neuropathol. Exp. Neurol. 55, 704-715.
18. Yang, F., Mak, K., Vinters, H.V., Frautschy, S.A. and Cole, G.M. (1994) NeuroReport 15, 2117-2120.
19. Corradin, S.B., Mauel, J., Donini, S.D., Quattrocchi, E. and Ricciardi-Castagnoli, P. (1993) Glia 7, 255-262.
20. Seglen, P.O. (1983) Methods Enzymol. 96, 737-764.
21. Grinde, B. and Seglen, P.O. (1980) Biochim. Biophys. Acta 632, 73-86.
22. Roher, A.E., Lowenson, J.D., Clarke, S., Woods, A.S., Cotter, R.J., Gowing, E. and Ball, M.J. (1993) Proc. Natl. Acad. Sci. USA 90, 10836-10840.
23. Iwatsubo, T., Odaka, A., Suzuki, N., Mizusawa, H., Nukina, N. and Ihara, Y. (1994) Neuron 13, 45-53.
24. Knauer, M.F., Soreghan, B., Burdick, D., Kosmoski, J. and Glabe, C.G. (1992) Proc. Natl. Acad. Sci. USA 89, 7437-7441.
25. Burdick, D., Soreghan, B., Kwon, M., Kosmoski, J., Knauer, M., Henschen, A., Yates, J., Cotman, C. and Glabe, C. (1992) J. Biol. Chem. 267, 546-554.
26. Paresce, D.M., Chung, H. and Maxneid, F.R. (1997) J. Biol. Chem. 272, 29390-29397.
27. Buktenica, S., Olenick, S.J., Salgia, R. and Frankfater, A. (1987) J. Biol. Chem. 262, 9469-9476.
28. Qiu, W.Q., Ye, Z., Kholodenko, D., Seubert, P. and Selkoe, D.J. (1997) J. Biol. Chem. 272, 6641-6646.
29. Naidu, A., Quon, D. and Cordell, B. (1995) J. Biol. Chem. 270, 1369-1374.
30. Cataldo, A.M., Hamilton, D.J. and Nixon, R.A. (1994) Brain Res. 640, 68-80.
31. Cataldo, A.M., Hamilton, D.J., Barnett, J.L., Paskevich, P.A. and Nixon, R.A. (1996) J. Neurosci. 16, 186-199.
32. Amano, T., Nakanishi, H., Kondo, T., Tanaka, T., Oka, M. and Yamamoto, K. (1995) Mech. Aging Dev. 83, 133-141.
33. Hamazaki, H. (1996) FEBS Lett. 396, 139-142.
34. McDermott, J.R. and Gibson, A.M. (1996) NeuroReport 7, 2163-2166.
35. Allsop, D., Haga, S., Haga, C., Ikeda, S., Mann, D.M. and Ishii, T. (1989) Neuropathol. Appl. Neurol. 15, 531-542.
36. Probst, A., Langui, D., Ipsen, S., Robakis, N. and Ulrich, J. (1991) Acta Neuropathol. 83, 21-29.