Effect of calmodulin antagonists on the compound action potential of the cochlea

Hearing Research

Volumn 145, Issue 1-2, 2000, Pages 59-64

  Tabuchi, Keiji ^a   Tsuji, Shigeki ^a   Hara, Akira ^a   Kusakari, Jun ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Calmodulin antagonist; Cochlea; Compound action potential; Ischemia

Indexed keywords

CALMODULIN; CALMODULIN INHIBITOR; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; TRIFLUOPERAZINE;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCHLEA INJURY; COCHLEA POTENTIAL; CONTROLLED STUDY; GUINEA PIG; HAIR CELL; ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY;

ACTION POTENTIALS; ANIMALS; CALMODULIN; COCHLEA; DIFFERENTIAL THRESHOLD; GUINEA PIGS; ISCHEMIA; PERFUSION; PERILYMPH; RECOVERY OF FUNCTION; REGIONAL BLOOD FLOW; REPERFUSION; SULFONAMIDES; TRIFLUOPERAZINE;

EID: 0034130011     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5955(00)00071-X     Document Type: Article

References (21)

1. Bobbin, R.P., Konishi, T., 1974. Action of cholinergic and anticholinergic drugs at the crossed olivo-cochlear bundle-hair cell junction. Acta Otolaryngol. 77, 55-65.
2. 2+ antagonist, reverses the negative summating potential recorded from the guinea pig cochlea. Hear. Res. 46, 277-288.
3. Bredt, D.S., Snyder, S.H., 1990. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc. Natl. Acad. Sci. USA 87, 682-685.
4. Clapham, D.E., 1995. Calcium signaling. Cell 80, 259-268.
5. Coling, D.E., Bartolami, S., Rhee, D., Neelands, T., 1998. Inhibition of calcium-dependent motility of cochlear outer hair cells by the protein kinase inhibitor, ML-9.. Hear. Res. 115, 175-183.
6. Dulon, D., Zajic, G., Schacht, J., 1990. Increasing intracellular free calcium induces circumferential contractions in isolated cochlear outer hair cells. J. Neurosci. 10, 1388-1397.
7. Imamura, S., Adams, J.C., 1996. Immunolocalization of peptide 19 and other calcium-binding proteins in the guinea pig cochlea. Anat. Embryol. 194, 407-418.
8. Jaramillo, F., 1995. Signal transduction in hair cells and its regulation by calcium. Neuron 15, 1227-1230.
9. Johnson, J.D., Wittenauer, L.A., 1983. A fluorescent calmodulin that reports the binding of hydrophobic inhibitory ligands. Biochem. J. 211, 473-479.
10. Kakehata, S., Nakagawa, T., Takasaka, T., Akaike, N., 1993. Cellular mechanism of acetylcholine-induced response in dissociated outer hair cells of guinea-pig cochlea. J. Physiol. 463, 227-244.
11. Kuroda, S., Nakai, A., Kristian, T., Siesjö, B.K., 1997. The calmodulin antagonist trifluoperazine in transient focal brain ischemia in rats. Anti-ischemic effect and therapeutic window. Stroke 28, 2539-2544.
12. Kusakari, J., Kambayashi, J., Kobayashi, T., Rokugo, M., Arakawa, E., Ohyama, K., Kaneko, Y., 1981. The effect of transient anoxia upon the cochlear potentials. Auris Nasus Larynx 8, 55-64.
13. Lahti, R.A., Evans, D.L., Stratman, N.C., Figur, L.M., 1993. Dopamine D4 versus D2 receptor selectivity of dopamine receptor antagonists: possible therapeutic implications. Eur. J. Pharmacol. 236, 483-486.
14. Pack, A.K., Slepecky, N.B., 1995. Cytoskeletal and calcium-binding proteins in the mammalian organ of Corti : cell type-specific proteins displaying longitudinal and radial gradients. Hear. Res. 91, 119-135.
15. Puschner, B., Schacht, J., 1997. Calmodulin-dependent protein kinases mediate calcium-induced slow motility of mammalian outer hair cells. Hear. Res. 110, 251-258.
16. Trzeciak, H.I., Kalacinski, W., Malecki, A., Kokot, D., 1995. Effect of neuroleptics on phospholipase A2 activity in the brain of rats. Eur. Arch. Psychiatry Clin. Neurosci. 245, 179-182.
17. Uematsu, D., Araki, N., Greenberg, J.H., Sladky, J., Reivich, M., 1991. Combined therapy with MK-801 and nimodipine for protection of ischemic brain damage. Neurology 41, 88-94.
18. Walker, R.G., Hudspeth, A.J., 1996. Calmodulin controls adaptation of mechanoelectrical transduction by hair cells of the bullfrog's sacculus. Proc. Natl. Acad. Sci. USA 93, 2203-2207.
19. Wang, K.K.W., Villalobo, A., Roufogalis, B.D., 1989. Calmodulin-binding proteins as calpain substrates. Biochem. J. 262, 693-706.
20. 2+ from hair cell stereocilia. J. Neurosci. 18, 610-624.
21. Zenner, H.P., Zimmermann, U., Schmitt, U., 1985. Reversible contraction of isolated mammalian cochlear hair cells. Hear. Res. 18, 127-133.